Page last updated: 2024-11-01

nicardipine and Tachycardia

nicardipine has been researched along with Tachycardia in 8 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Tachycardia: Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia.

Research Excerpts

ExcerptRelevanceReference
"We compared the efficacy of the combination of enalaprilat/labetalol with that of enalaprilat/nicardipine to prevent emergence postcraniotomy hypertension."9.09A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery. ( Broad, C; Ferri, E; Kross, RA; Leung, D; Melendez, JA; Pratila, M; Veronesi, M, 2000)
"Intravenous diltiazem (10-300 micrograms/kg), verapamil (10-300 micrograms/kg), nifedipine (1-100 micrograms/kg) and nicardipine (1-100 micrograms/kg) inhibited the tachycardia caused by cardiac sympathetic nerve stimulation (SNS, 0."7.68Inhibitory effects of diltiazem, verapamil, nifedipine, and nicardipine on sympathetic tachycardia in decentralized hearts of anesthetized dogs. ( Kimura, T; Mukaiyama, O; Satoh, E; Satoh, S, 1990)
"We compared the efficacy of the combination of enalaprilat/labetalol with that of enalaprilat/nicardipine to prevent emergence postcraniotomy hypertension."5.09A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery. ( Broad, C; Ferri, E; Kross, RA; Leung, D; Melendez, JA; Pratila, M; Veronesi, M, 2000)
" This study was designed to investigate the acute effects of local application of a SMF to neck or pelvic region under pharmacologically modulated BP; norepinephrine (NE)-induced hypertension as well as an L-type voltage-gated Ca(2+) channel blocker, nicardipine (NIC)-induced hypotension in conscious rabbits."3.73Effects of neck exposure to 5.5 mT static magnetic field on pharmacologically modulated blood pressure in conscious rabbits. ( Ohkubo, C; Okano, H, 2005)
"Intravenous diltiazem (10-300 micrograms/kg), verapamil (10-300 micrograms/kg), nifedipine (1-100 micrograms/kg) and nicardipine (1-100 micrograms/kg) inhibited the tachycardia caused by cardiac sympathetic nerve stimulation (SNS, 0."3.68Inhibitory effects of diltiazem, verapamil, nifedipine, and nicardipine on sympathetic tachycardia in decentralized hearts of anesthetized dogs. ( Kimura, T; Mukaiyama, O; Satoh, E; Satoh, S, 1990)
"Nicardipine was given by slow intravenous injection."1.27Baroreflex sensitivity alteration following transient hemispheric ischaemia in rats: protective effect of alphamethyldopa and guanfacine. ( Elghozi, JL; Meyer, P; Saad, MA, 1986)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's4 (50.00)18.2507
2000's2 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Okano, H1
Ohkubo, C1
Wig, J1
Sharma, M1
Baichoo, N1
Agarwal, A1
Wu, KD1
Hsieh, BS1
Chu, TS1
Yen, TS1
Kumagai, K1
Suzuki, H1
Ichikawa, M1
Jimbo, M1
Nishizawa, M1
Ryuzaki, M1
Saruta, T1
Kross, RA1
Ferri, E1
Leung, D1
Pratila, M1
Broad, C1
Veronesi, M1
Melendez, JA1
Satoh, E1
Mukaiyama, O1
Kimura, T1
Satoh, S1
Saad, MA1
Elghozi, JL1
Meyer, P1
Rousseau, MF1
Hanet, C1
Pardonge-Lavenne, E1
Van den Berghe, G1
Van Hoof, F1
Pouleur, H1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficiency of Intravenous Lidocaine to Reduce Coughing and the Hemodynamic Changes Associated to Tracheal Extubation[NCT03731429]Phase 4144 participants (Anticipated)Interventional2019-04-05Recruiting
Nicardipine Versus Esmolol for Management of Emergence Hypertension After Craniotomy[NCT01951950]Phase 140 participants (Actual)Interventional2013-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Failure of Drug to Control Systolic Blood Pressure (SBP) < 140 mmHg

(NCT01951950)
Timeframe: 1 hour postoperatively

Interventionparticipants (Number)
Nicardipine1
Esmolol11

Trials

2 trials available for nicardipine and Tachycardia

ArticleYear
Nicardipine and verapamil attenuate the pressor response to laryngoscopy and intubation.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:12

    Topics: Adult; Anesthesia, General; Blood Pressure; Diastole; Double-Blind Method; Elective Surgical Procedu

1994
A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Anesth

2000
A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Anesth

2000
A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Anesth

2000
A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Anesth

2000

Other Studies

6 other studies available for nicardipine and Tachycardia

ArticleYear
Effects of neck exposure to 5.5 mT static magnetic field on pharmacologically modulated blood pressure in conscious rabbits.
    Bioelectromagnetics, 2005, Volume: 26, Issue:6

    Topics: Animals; Baroreflex; Blood Pressure; Bradycardia; Calcium Channel Blockers; Carotid Sinus; Conscious

2005
The acute effect of nicardipine on the renin-angiotensin-aldosterone system in salt-sensitive essential hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1993, Volume: 15, Issue:1

    Topics: Adult; Blood Pressure; Female; Furosemide; Heart Rate; Humans; Hypertension; Male; Middle Aged; Natr

1993
Comparison of early and late start of antihypertensive agents and baroreceptor reflexes.
    Hypertension (Dallas, Tex. : 1979), 1996, Volume: 27, Issue:2

    Topics: Aging; Animals; Antihypertensive Agents; Atenolol; Baroreflex; Blood Pressure; Enalapril; Heart Rate

1996
Inhibitory effects of diltiazem, verapamil, nifedipine, and nicardipine on sympathetic tachycardia in decentralized hearts of anesthetized dogs.
    Journal of cardiovascular pharmacology, 1990, Volume: 16, Issue:4

    Topics: Analysis of Variance; Animals; Blood Pressure; Coronary Circulation; Diltiazem; Dogs; Dose-Response

1990
Baroreflex sensitivity alteration following transient hemispheric ischaemia in rats: protective effect of alphamethyldopa and guanfacine.
    Clinical and experimental pharmacology & physiology, 1986, Volume: 13, Issue:7

    Topics: Animals; Blood Pressure; Enalapril; Guanfacine; Guanidines; Heart Rate; Ischemic Attack, Transient;

1986
Changes in myocardial metabolism during therapy in patients with chronic stable angina: a comparison of long-term dosing with propranolol and nicardipine.
    Circulation, 1986, Volume: 73, Issue:6

    Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Cardiac Pacing, Artificial; Chronic Disease; Exercise

1986