Page last updated: 2024-11-01

nicardipine and Spasm

nicardipine has been researched along with Spasm in 7 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Spasm: An involuntary contraction of a muscle or group of muscles. Spasms may involve SKELETAL MUSCLE or SMOOTH MUSCLE.

Research Excerpts

ExcerptRelevanceReference
"Nicardipine is a safe and effective alternative of verapamil in preventing spasm of radial artery conduit."6.90Preventing spasm of the radial artery conduit during coronary artery bypass grafting: Nicardipine versus verapamil. ( Haanschoten, M; Özdemir, AB; Özdemir, HI; Soliman-Hamad, MA; van Dijk, CHB; van Straten, BHM, 2019)
" 1) H2O2 dissolved in different concentrations produced arterial contractions similar to those by equimolar Oxy-Hb, showing similar dose-response curves."5.27[On the mechanism underlying spasmogenic actions of oxy-hemoglobin on the cerebral artery, analyzed from the inhibitory effects of nicardipine, procaine and indomethacin]. ( Doi, M, 1988)
"Nicardipine is a safe and effective alternative of verapamil in preventing spasm of radial artery conduit."2.90Preventing spasm of the radial artery conduit during coronary artery bypass grafting: Nicardipine versus verapamil. ( Haanschoten, M; Özdemir, AB; Özdemir, HI; Soliman-Hamad, MA; van Dijk, CHB; van Straten, BHM, 2019)
"Arterial vasospasm is a common problem in microsurgery."1.29Porcine gastroepiploic artery as an in vitro experimental model to study vasodilators in microsurgery. ( Chen, D; Harakal, C; Kim, DC; Mitra, A; Perrotta, VJ; Shuman, CA; Wendling, WW, 1996)
" 1) H2O2 dissolved in different concentrations produced arterial contractions similar to those by equimolar Oxy-Hb, showing similar dose-response curves."1.27[On the mechanism underlying spasmogenic actions of oxy-hemoglobin on the cerebral artery, analyzed from the inhibitory effects of nicardipine, procaine and indomethacin]. ( Doi, M, 1988)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's4 (57.14)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Bouchahda, N2
Ben Abdessalem, MA2
Ben Hlima, N2
Ben Messaoud, M2
Denguir, H2
Boussaada, MM2
Saoudi, W2
Jamel, A2
Hassine, M2
Bouraoui, H2
Mahjoub, M2
Mahdhaoui, A2
Jeridi, G2
Betbout, F2
Gamra, H2
Özdemir, HI1
van Dijk, CHB1
Özdemir, AB1
van Straten, BHM1
Haanschoten, M1
Soliman-Hamad, MA1
Kim, DC1
Chen, D1
Perrotta, VJ1
Shuman, CA1
Wendling, WW1
Harakal, C1
Mitra, A1
Grigore, AM1
Castro, JL1
Swistel, D1
Thys, DM1
Mychaskiw, G1
Hoehner, P1
Radermecker, MA1
Larbuisson, R1
Doi, M1

Trials

2 trials available for nicardipine and Spasm

ArticleYear
Combination Therapy With Nicardipine and Isosorbide Dinitrate to Prevent Spasm in Transradial Percutaneous Coronary Intervention (from the NISTRA Multicenter Double-Blind Randomized Controlled Trial).
    The American journal of cardiology, 2023, 02-01, Volume: 188

    Topics: Double-Blind Method; Humans; Isosorbide Dinitrate; Midazolam; Morphine Derivatives; Nicardipine; Per

2023
Combination Therapy With Nicardipine and Isosorbide Dinitrate to Prevent Spasm in Transradial Percutaneous Coronary Intervention (from the NISTRA Multicenter Double-Blind Randomized Controlled Trial).
    The American journal of cardiology, 2023, 02-01, Volume: 188

    Topics: Double-Blind Method; Humans; Isosorbide Dinitrate; Midazolam; Morphine Derivatives; Nicardipine; Per

2023
Combination Therapy With Nicardipine and Isosorbide Dinitrate to Prevent Spasm in Transradial Percutaneous Coronary Intervention (from the NISTRA Multicenter Double-Blind Randomized Controlled Trial).
    The American journal of cardiology, 2023, 02-01, Volume: 188

    Topics: Double-Blind Method; Humans; Isosorbide Dinitrate; Midazolam; Morphine Derivatives; Nicardipine; Per

2023
Combination Therapy With Nicardipine and Isosorbide Dinitrate to Prevent Spasm in Transradial Percutaneous Coronary Intervention (from the NISTRA Multicenter Double-Blind Randomized Controlled Trial).
    The American journal of cardiology, 2023, 02-01, Volume: 188

    Topics: Double-Blind Method; Humans; Isosorbide Dinitrate; Midazolam; Morphine Derivatives; Nicardipine; Per

2023
Preventing spasm of the radial artery conduit during coronary artery bypass grafting: Nicardipine versus verapamil.
    Journal of cardiac surgery, 2019, Volume: 34, Issue:12

    Topics: Administration, Topical; Calcium Channel Blockers; Coronary Artery Bypass; Female; Humans; Linear Mo

2019

Other Studies

5 other studies available for nicardipine and Spasm

ArticleYear
Porcine gastroepiploic artery as an in vitro experimental model to study vasodilators in microsurgery.
    Annals of plastic surgery, 1996, Volume: 36, Issue:5

    Topics: Animals; Arteries; Culture Techniques; Diltiazem; Microsurgery; Nicardipine; Spasm; Swine; Vasodilat

1996
Nicardipine infusion for the prevention of radial artery spasm during myocardial revascularization.
    Journal of cardiothoracic and vascular anesthesia, 1998, Volume: 12, Issue:5

    Topics: Aged; Coronary Artery Bypass; Humans; Male; Nicardipine; Peripheral Vascular Diseases; Radial Artery

1998
Nicardipine infusion for radial artery spasm--a cautionary note.
    Journal of cardiothoracic and vascular anesthesia, 1999, Volume: 13, Issue:4

    Topics: Calcium Channel Blockers; Coronary Artery Bypass; Humans; Nicardipine; Radial Artery; Spasm; Vasocon

1999
Nicardipine protocol for coronary artery bypass grafting using the radial artery: clinical and angiographic data.
    Journal of cardiothoracic and vascular anesthesia, 1999, Volume: 13, Issue:4

    Topics: Calcium Channel Blockers; Coronary Artery Bypass; Humans; Nicardipine; Radial Artery; Spasm; Vasocon

1999
[On the mechanism underlying spasmogenic actions of oxy-hemoglobin on the cerebral artery, analyzed from the inhibitory effects of nicardipine, procaine and indomethacin].
    No shinkei geka. Neurological surgery, 1988, Volume: 16, Issue:2

    Topics: Animals; Cattle; Cerebral Arterial Diseases; In Vitro Techniques; Indomethacin; Muscle, Smooth, Vasc

1988