nicardipine has been researched along with Pregnancy in 84 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " After 30 inclusions, the study was stopped because of the high rate of persistent hypertension using ketanserin and the high rate of maternal side effects using dihydralazine and the apparent succesful use of the rescue drug nicardipine." | 9.20 | Ketanserin versus dihydralazine for the treatment of severe hypertension in early-onset preeclampsia: a double blind randomized controlled trial. ( Bijvank, SW; Duvekot, JJ; Edens, MA; Hanff, LM; Roofthooft, DW; Steegers, EA; Visser, W; Vulto, AG, 2015) |
| "Our results suggest that long-term treatment with nicardipine for severe pre-eclampsia is as effective and safe as a short- and medium-term treatment." | 9.10 | Long-term treatment with nicardipine for severe pre-eclampsia. ( Kinoshita, K; Seki, H; Takeda, S, 2002) |
| "Nicardipine and labetalol are effective and safe in the initial treatment of severe hypertension of pregnancy." | 9.10 | Short-term treatment of severe hypertension of pregnancy: prospective comparison of nicardipine and labetalol. ( Abroug, F; Boussarssar, M; Elatrous, S; Marghli, S; Nouira, S; Ouanes Besbes, L; Sakkouhi, M, 2002) |
| "To assess the efficacy in lowering blood pressure, and the safety for mother and foetus of an acute nicardipine therapy in severe pre-eclampsia." | 9.09 | Intravenous nicardipine for severe hypertension in pre-eclampsia--effects of an acute treatment on mother and foetus. ( Aya, AG; Eledjam, JJ; Hoffet, M; Mangin, R, 1999) |
| "Forty pregnant patients with mild or moderate hypertension received oral nicardipine 20 mg three times a day (mean duration of treatment 9 +/- 2." | 9.07 | Nicardipine treatment of hypertension during pregnancy. ( Carbonne, B; Jannet, D; Khelifati, Y; Milliez, J; Touboul, C, 1993) |
| "One hundred pregnant patients with mild or moderate hypertension followed at the Centre Hospitalier Intercommunal de Créteil (France) were randomly allocated to treatment with either nicardipine or metoprolol." | 9.07 | Nicardipine versus metoprolol in the treatment of hypertension during pregnancy: a randomized comparative trial. ( Carbonne, B; Jannet, D; Milliez, J; Sebban, E, 1994) |
| "Nicardipine is a potent drug to control hypertension during pregnancy with side effects including maternal headaches, nausea and tachycardia." | 8.90 | The optimal treatment of severe hypertension in pregnancy: update of the role of nicardipine. ( de Groot, CJ; Meuleman, T; Nooij, LS; Roelofs, R; Visser, S; Vos, P, 2014) |
| "To evaluate the efficacy and safety of intravenous nicardipine for the treatment of severe hypertension in pregnancy." | 8.86 | Nicardipine for the treatment of severe hypertension in pregnancy: a review of the literature. ( Duvekot, JJ; Nij Bijvank, SW, 2010) |
| "This multicenter, retrospective case series included all pregnant women beyond 20 weeks of gestation with severe antepartum hypertension that were treated with intravenous nicardipine." | 8.12 | Nicardipine for treating severe antepartum hypertension during pregnancy: Nine years of experience in more than 800 women. ( Cornette, JC; Duvekot, JJ; Edens, MA; Hengst, M; Huigen, S; Nij Bijvank, SW; Winkelen, AV, 2022) |
| "The aim of this study was to compare radial arterial catheter-derived pressure with oscillometric blood pressure in women with severe peripartum hypertension undergoing urgent treatment with intravenous nicardipine at a maternal intensive care unit." | 8.02 | Intra-arterial versus oscillometric blood pressure measurements in women with severe peripartum hypertension undergoing urgent treatment with nicardipine: An observational study. ( Gan, S; Lan, L; Li, L; Qi, H; Qin, J; Ren, L; Xiang, B; Yan, Y; Zhang, Y, 2021) |
| "To investigate the efficacy of low-dose intravenous nicardipine for emergent management of severe postpartum hypertension in maternal intensive care units (ICUs)." | 7.96 | Efficacy of low-dose nicardipine for emergent treatment of severe postpartum hypertension in maternal intensive care units: An observational study. ( Gan, S; Lan, L; Li, L; Qi, H; Qin, J; Ren, L; Yan, Y; Zhang, Y, 2020) |
| "The authors report a heart failure and a collapse following concurrently administration of nicardipine and magnesium sulfate." | 7.78 | [Complications of association magnesium sulfate with nicardipine during preeclampsia: report of 2 cases]. ( Alassas, N; Carles, G; Dallah, F; Helou, J; Ibrahim, N, 2012) |
| "We report three cases of acute pulmonary edema that occurred during treatment by intravenous tocolysis using nicardipine in twin pregnancy patients with no previous heart problems." | 7.75 | [Acute pulmonary edema occurred during tocolytic treatment using nicardipine in a twin pregnancy. Report of three cases]. ( Caroit, Y; Demeure, D; Desjars, P; Esbelin, J; Le Trong, A; Philippe, HJ; Pigeau, H; Winer, N, 2009) |
| " We report three cases of pulmonary edema during preterm labor associated with the use of calcium channel blocker, intravenous nicardipine, widely used for tocolysis in France." | 7.73 | [Acute pulmonary edema during preterm labor: role of nicardipine tocolysis (three cases)]. ( Apfelbaum, D; Boccara, F; Carbonne, B; Cohen, A; Janower, S; Lejeune, V, 2005) |
| "We report the case of a 38-year-old parturient at 30 weeks 2 days term of a multiple pregnancy who experienced acute pulmonary edema more than 48 hours after tocolytic treatment with nicardipine and salbutamol." | 7.73 | [Acute pulmonary edema during nicardipine and salbutamol therapy for preterm labor in twin pregnancy]. ( Chapuis, C; Debaty, G; Koch, FX; Menthonnex, E; Menthonnex, P; Pons, JC; Rancurel, E, 2005) |
| " Blood pressure was maintained by bolus administration of nicardipine for the removal of pheochromocytoma." | 7.70 | Anesthetic management for pheochromocytoma resection using spinal cord stimulation and intravenous nicardipine--a case report. ( Hanzawa, K; Motoyama, Y; Shiraishi, M, 1999) |
| "Nicardipine has been used extensively in different clinical settings including neurosurgery, cardiothoracic surgery, transplant medicine, and internal medicine patients." | 6.45 | Acute antihypertensive therapy in pregnancy-induced hypertension: is nicardipine the answer? ( Hankins, GD; Pacheco, LD; Vadhera, RB, 2009) |
| "Nicardipine was infused for a mean 11." | 5.40 | Placental transfer of intravenous nicardipine and disposition into breast milk during the control of hypertension in women with pre-eclampsia. ( Fukatsu, M; Ichinose, S; Masuko, H; Matsumura, H; Mera, A; Miyashita, A; Ono, Y; Seki, H; Takagi, K, 2014) |
| " After 30 inclusions, the study was stopped because of the high rate of persistent hypertension using ketanserin and the high rate of maternal side effects using dihydralazine and the apparent succesful use of the rescue drug nicardipine." | 5.20 | Ketanserin versus dihydralazine for the treatment of severe hypertension in early-onset preeclampsia: a double blind randomized controlled trial. ( Bijvank, SW; Duvekot, JJ; Edens, MA; Hanff, LM; Roofthooft, DW; Steegers, EA; Visser, W; Vulto, AG, 2015) |
| " In nicardipine group, the pregnancy was prolonged more than 48 hours in 87." | 5.13 | Nicardipine versus salbutamol in the treatment of premature labor: comparison of their efficacy and side effects. ( Abdennadheur, W; Amouri, H; Ben Amar, H; Gargouri, A; Guermazi, M; Hadj Taib, H; Kallel, W; Trabelsi, K; Zribi, A, 2008) |
| "Nicardipine and labetalol are effective and safe in the initial treatment of severe hypertension of pregnancy." | 5.10 | Short-term treatment of severe hypertension of pregnancy: prospective comparison of nicardipine and labetalol. ( Abroug, F; Boussarssar, M; Elatrous, S; Marghli, S; Nouira, S; Ouanes Besbes, L; Sakkouhi, M, 2002) |
| "Our results suggest that long-term treatment with nicardipine for severe pre-eclampsia is as effective and safe as a short- and medium-term treatment." | 5.10 | Long-term treatment with nicardipine for severe pre-eclampsia. ( Kinoshita, K; Seki, H; Takeda, S, 2002) |
| "To assess the efficacy in lowering blood pressure, and the safety for mother and foetus of an acute nicardipine therapy in severe pre-eclampsia." | 5.09 | Intravenous nicardipine for severe hypertension in pre-eclampsia--effects of an acute treatment on mother and foetus. ( Aya, AG; Eledjam, JJ; Hoffet, M; Mangin, R, 1999) |
| "Forty pregnant patients with mild or moderate hypertension received oral nicardipine 20 mg three times a day (mean duration of treatment 9 +/- 2." | 5.07 | Nicardipine treatment of hypertension during pregnancy. ( Carbonne, B; Jannet, D; Khelifati, Y; Milliez, J; Touboul, C, 1993) |
| "One hundred pregnant patients with mild or moderate hypertension followed at the Centre Hospitalier Intercommunal de Créteil (France) were randomly allocated to treatment with either nicardipine or metoprolol." | 5.07 | Nicardipine versus metoprolol in the treatment of hypertension during pregnancy: a randomized comparative trial. ( Carbonne, B; Jannet, D; Milliez, J; Sebban, E, 1994) |
| "Nicardipine is a potent drug to control hypertension during pregnancy with side effects including maternal headaches, nausea and tachycardia." | 4.90 | The optimal treatment of severe hypertension in pregnancy: update of the role of nicardipine. ( de Groot, CJ; Meuleman, T; Nooij, LS; Roelofs, R; Visser, S; Vos, P, 2014) |
| "To evaluate the efficacy and safety of intravenous nicardipine for the treatment of severe hypertension in pregnancy." | 4.86 | Nicardipine for the treatment of severe hypertension in pregnancy: a review of the literature. ( Duvekot, JJ; Nij Bijvank, SW, 2010) |
| "This multicenter, retrospective case series included all pregnant women beyond 20 weeks of gestation with severe antepartum hypertension that were treated with intravenous nicardipine." | 4.12 | Nicardipine for treating severe antepartum hypertension during pregnancy: Nine years of experience in more than 800 women. ( Cornette, JC; Duvekot, JJ; Edens, MA; Hengst, M; Huigen, S; Nij Bijvank, SW; Winkelen, AV, 2022) |
| "The aim of this study was to compare radial arterial catheter-derived pressure with oscillometric blood pressure in women with severe peripartum hypertension undergoing urgent treatment with intravenous nicardipine at a maternal intensive care unit." | 4.02 | Intra-arterial versus oscillometric blood pressure measurements in women with severe peripartum hypertension undergoing urgent treatment with nicardipine: An observational study. ( Gan, S; Lan, L; Li, L; Qi, H; Qin, J; Ren, L; Xiang, B; Yan, Y; Zhang, Y, 2021) |
| "To investigate the efficacy of low-dose intravenous nicardipine for emergent management of severe postpartum hypertension in maternal intensive care units (ICUs)." | 3.96 | Efficacy of low-dose nicardipine for emergent treatment of severe postpartum hypertension in maternal intensive care units: An observational study. ( Gan, S; Lan, L; Li, L; Qi, H; Qin, J; Ren, L; Yan, Y; Zhang, Y, 2020) |
| " She developed a prolonged and deep neuromuscular blockade, which was antagonized three hours later with neostigmine." | 3.83 | Prolonged neuromuscular block in a preeclamptic patient induced by magnesium sulfate. ( Berdai, MA; Harandou, M; Labib, S, 2016) |
| "Ten severely pre-eclamptic pregnant women who required intravenous nicardipine for severe hypertension were included in this prospective observational trial." | 3.83 | Hemodynamic effects of intravenous nicardipine in severely pre-eclamptic women with a hypertensive crisis. ( Buijs, EA; Cornette, J; Duvekot, JJ; Herzog, E; Meima, M; Rizopoulos, D; Roos-Hesselink, JW; Steegers, EA, 2016) |
| "Thirty-four spontaneous cases regarding pregnancy women who experienced APO following nicardipine treatment as tocolytic were collected." | 3.81 | Off-label use of nicardipine as tocolytic and acute pulmonary oedema: a post-marketing analysis of adverse drug reaction reports in EudraVigilance. ( Biagi, C; Buccellato, E; Cupelli, A; Melis, M; Motola, D; Sottosanti, L; Vaccheri, A, 2015) |
| "The authors report a heart failure and a collapse following concurrently administration of nicardipine and magnesium sulfate." | 3.78 | [Complications of association magnesium sulfate with nicardipine during preeclampsia: report of 2 cases]. ( Alassas, N; Carles, G; Dallah, F; Helou, J; Ibrahim, N, 2012) |
| "We report three cases of acute pulmonary edema that occurred during treatment by intravenous tocolysis using nicardipine in twin pregnancy patients with no previous heart problems." | 3.75 | [Acute pulmonary edema occurred during tocolytic treatment using nicardipine in a twin pregnancy. Report of three cases]. ( Caroit, Y; Demeure, D; Desjars, P; Esbelin, J; Le Trong, A; Philippe, HJ; Pigeau, H; Winer, N, 2009) |
| "We report the case of a 31-yr-old parturient at 34 weeks gestation of a twin pregnancy, who experienced acute pulmonary edema after tocolytic treatment with nifedipine, nicardipine and atosiban of > 48 hr in duration." | 3.74 | [Non-invasive ventilation for pulmonary edema associated with tocolytic agents during labour for a twin pregnancy]. ( Bazin, JE; Bolandard, F; Chanséaume, S; Constantin, JM; Gallot, D; Perbet, S; Vignaud, M; Zénut, M, 2008) |
| " We report three cases of pulmonary edema during preterm labor associated with the use of calcium channel blocker, intravenous nicardipine, widely used for tocolysis in France." | 3.73 | [Acute pulmonary edema during preterm labor: role of nicardipine tocolysis (three cases)]. ( Apfelbaum, D; Boccara, F; Carbonne, B; Cohen, A; Janower, S; Lejeune, V, 2005) |
| "Nicardipine infusion was started for temporizing management of pre-eclampsia at a dosage of 3 mg/h and was subsequently titrated according to blood pressure." | 3.73 | Intravenous use of the calcium-channel blocker nicardipine as second-line treatment in severe, early-onset pre-eclamptic patients. ( Bartels, PA; Bijvank, BN; Hanff, LM; Roofthooft, DW; Steegers, EA; Visser, W; Vulto, AG, 2005) |
| "We report the case of a 38-year-old parturient at 30 weeks 2 days term of a multiple pregnancy who experienced acute pulmonary edema more than 48 hours after tocolytic treatment with nicardipine and salbutamol." | 3.73 | [Acute pulmonary edema during nicardipine and salbutamol therapy for preterm labor in twin pregnancy]. ( Chapuis, C; Debaty, G; Koch, FX; Menthonnex, E; Menthonnex, P; Pons, JC; Rancurel, E, 2005) |
| "We studied the effects of hydralazine, nicardipine, nitroglycerin, and fenoldopam (a dopamine D1-agonist) on isolated human umbilical arteries (HUA) from patients classified as normotensive and with pregnancy-induced hypertension (PIH)." | 3.72 | The vasodilatory effects of hydralazine, nicardipine, nitroglycerin, and fenoldopam in the human umbilical artery. ( Arias, ME; Levy, JH; Sato, N; Szlam, F; Tanaka, KA; Tsuda, A, 2003) |
| " Blood pressure was maintained by bolus administration of nicardipine for the removal of pheochromocytoma." | 3.70 | Anesthetic management for pheochromocytoma resection using spinal cord stimulation and intravenous nicardipine--a case report. ( Hanzawa, K; Motoyama, Y; Shiraishi, M, 1999) |
| " Intermittent injection of nicardipine was quite effective to control the hypertension during anesthesia." | 3.69 | [Anesthesia for cesarean section in a patient with intracranial A-V malformation]. ( Kawada, K; Kubota, M; Ogawa, H; Tamakawa, S; Terao, M, 1995) |
| " Fifteen patients with mild pre-eclampsia were chronically treated with oral pindolol." | 3.68 | The effect of acute and chronic antihypertensive therapy on maternal and fetoplacental Doppler velocimetry. ( Bjornsson, S; Cameron, AD; Fairlie, FM; Mathers, A; Walker, JJ, 1992) |
| "Calcium channel blockers such as nicardipine act as arterial vasodilators and are effective in the treatment of hypertension." | 3.67 | Fetal vascular responses to maternal nicardipine administration in the hypertensive ewe. ( Parisi, VM; Salinas, J; Stockmar, EJ, 1989) |
| "Oral nicardipine is an effective, safe, and well-tolerated tocolytic agent." | 2.69 | Oral nicardipine versus intravenous magnesium sulfate for the treatment of preterm labor. ( Dickerson, GA; Fischer, RG; Larmon, JE; May, WL; Morrison, JC; Ross, BS, 1999) |
| "Nicardipine is a tocolytic agent as effective as salbutamol in the treatment of premature labor." | 2.68 | Nicardipine versus salbutamol in the treatment of premature labor. A prospective randomized study. ( Abankwa, A; Carbonne, B; Guyard, B; Jannet, D; Marpeau, L; Milliez, J, 1997) |
| "We present a case of diffuse cerebral vasospasm, which improved with intra-arterial nicardipine." | 2.47 | Intra-arterial nicardipine for the treatment of cerebral vasospasm in postpartum cerebral angiopathy: a case study and review of literature. ( Husmann, K; Lele, A; Lyon, T; Pollack, A; Reeves, A, 2011) |
| "Nicardipine has been used extensively in different clinical settings including neurosurgery, cardiothoracic surgery, transplant medicine, and internal medicine patients." | 2.45 | Acute antihypertensive therapy in pregnancy-induced hypertension: is nicardipine the answer? ( Hankins, GD; Pacheco, LD; Vadhera, RB, 2009) |
| "Risk factors for the development of preeclampsia include microvascular diseases, such as diabetes mellitus; vascular and connective tissue disorders; hypertension; antiphospholipid antibody syndrome; and nephropathy." | 2.45 | Pharmacotherapeutic options for the treatment of preeclampsia. ( Baldwin, K; McCoy, S, 2009) |
| "Hypertension that complicates preeclampsia in pregnancy is a disorder that requires special consideration in both prevention and pharmacologic treatment." | 2.43 | Pathophysiology and medical management of systemic hypertension in preeclampsia. ( Frishman, WH; Schlocker, SJ; Tejani, N; Veresh, M, 2006) |
| " Such data in pregnant women may affect the choice of optimal drug dosage and route of administration." | 2.42 | Pharmacokinetics of tocolytic agents. ( Cabrol, D; Carbonne, B; Tsatsaris, V, 2004) |
| "Severe hypertension is a common clinical problem in the United States, encountered in various clinical settings." | 2.41 | The diagnosis and management of hypertensive crises. ( Marik, PE; Varon, J, 2000) |
| "The worldwide incidence of coronavirus disease 2019 (COVID-19) infection is rapidly increasing, but there exists limited information on coronavirus disease 2019 in pregnancy." | 1.56 | Coronavirus disease 2019 in pregnancy: early lessons. ( Baptiste, C; Breslin, N; D'Alton, M; Fuchs, K; Goffman, D; Gyamfi-Bannerman, C; Miller, R, 2020) |
| "Nicardipine was infused for a mean 11." | 1.40 | Placental transfer of intravenous nicardipine and disposition into breast milk during the control of hypertension in women with pre-eclampsia. ( Fukatsu, M; Ichinose, S; Masuko, H; Matsumura, H; Mera, A; Miyashita, A; Ono, Y; Seki, H; Takagi, K, 2014) |
| "Glyburide (200 ng/mL) was introduced to maternal and fetal compartments through a recirculating 2 hour perfusion, and its transplacental transport was tested with (n = 8) or without (n = 8) cannabidoil." | 1.39 | Cannabidiol enhances xenobiotic permeability through the human placental barrier by direct inhibition of breast cancer resistance protein: an ex vivo study. ( Ben-Zvi, Z; Erez, O; Eshkoli, T; Feinshtein, V; Holcberg, G; Sheiner, E; Sheizaf, B, 2013) |
| "The antenatal diagnosis of aortic dissection carries a grave prognosis." | 1.39 | Successful management of aortic dissection in a patient with Marfan syndrome during pregnancy. ( Chang, CY; Chen, PH; Lam, CW; Yang, JM, 2013) |
| "Oxytocin is a commonly used uterotonic that can cause significant and even fatal hypotension, particularly when given as a bolus." | 1.35 | The hemodynamics of oxytocin and other vasoactive agents during neuraxial anesthesia for cesarean delivery: findings in six cases. ( Archer, TL; Carter, B; Knape, K; Liles, D; Wheeler, AS, 2008) |
| " The highest umbilical cord concentration found after maternal dosage of 4." | 1.34 | Nicardipine in pre-eclamptic patients: placental transfer and disposition in breast milk. ( Bartels, PA; Hanff, LM; Mathot, RA; Steegers, EA; Visser, W; Vulto, AG, 2007) |
| "We report here four cases of pulmonary edema in pregnant women treated with nicardipine (Loxen) for preterm labor." | 1.34 | [Pulmonary edema during calcium-channel blockers therapy: role of predisposing or pharmacologic factors?]. ( Akerman, G; Cabrol, D; Goffinet, F; Jacqmin, S; Mignon, A; Tsatsaris, V, 2007) |
| "We report a case of pulmonary edema induced by nicardipine therapy for tocolysis in a pregnant 27-yr-old patient admitted to our hospital for preterm labor with intact membranes at 27 wk of gestation." | 1.32 | Pulmonary edema induced by calcium-channel blockade for tocolysis. ( Adam, M; Bal, L; Brocas, E; Tenaillon, A; Thierry, S; Van de Louw, A, 2004) |
| "Rofecoxib has a potent tocolytic effect in vitro." | 1.31 | In vitro study of tocolytic effect of rofecoxib, a specific cyclo-oxygenase 2 inhibitor. Comparison and combination with other tocolytic agents. ( Benchaib, M; Doret, M; Gharib, C; Mellier, G; Pasquier, JC; Piacenza, JM, 2002) |
| "For the anesthetic management of moyamoya disease patients, especially in delivery, it is important to avoid hemodynamic changes and to maintain cerebral blood flow (CBF)." | 1.30 | Propofol anesthesia for cesarean section successfully managed in a patient with moyamoya disease. ( Furuya, A; Kumazawa, T; Matsukawa, T; Ozaki, M, 1998) |
| " It is suggested that a suitable dosage of fentanyl is effective without causing serious side effects for neonate." | 1.29 | [Anesthesia for a patient with HELLP syndrome]. ( Sakio, H; Satoh, T; Takahashi, H, 1996) |
| "When nicardipine (10(-5) M) was applied, contractions induced by 118mM-K+ were completely inhibited, but contractions induced by serotonin could not be completely abolished, i." | 1.28 | Effect of vasoconstrictor and vasodilator on isolated human umbilical vein. ( Ichihara, J; Izumi, H; Koyama, Y; Mohtai, H; Shirakawa, K, 1991) |
| "Nicardipine was then administered intravenously at 20 micrograms/kg/min over 2 minutes while the angiotensin II infusion was maintained." | 1.28 | Placental vascular responses to nicardipine in the hypertensive ewe. ( Parisi, VM; Salinas, J; Stockmar, EJ, 1989) |
| "Nicardipine HCl treatment was associated with a rise in pulse rate and concomitant fall in mean arterial pressure." | 1.27 | Cardiovascular and uterine blood flow changes during nicardipine HCl tocolysis in the rabbit. ( Holbrook, RH; Katz, M; Lirette, M, 1987) |
| "The effects of two dosage schedules of nicardipine, a calcium-entry blocker, were studied in the pregnant rabbit during induced preterm uterine contractions and compared with the effects of ritodrine hydrochloride." | 1.27 | Cardiovascular and tocolytic effects of nicardipine HCl in the pregnant rabbit: comparison with ritodrine HCl. ( Holbrook, RH; Katz, M; Lirette, M, 1987) |
| "Similarly, when premature labor was induced by ovariectomy (OVX) on day 16, OVX control rats (n = 6) receiving 5 microgram/day of estradiol delivered 82% of the fetuses within 48 hours of OVX, whereas the rats treated with nicardipine (n = 7) delivered only 4% of the fetuses." | 1.26 | Deactivation of the uterus during normal and premature labor by the calcium antagonist nicardipine. ( Csapo, AI; Henzl, MR; Puri, CP; Tarro, S, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (11.90) | 18.7374 |
| 1990's | 20 (23.81) | 18.2507 |
| 2000's | 29 (34.52) | 29.6817 |
| 2010's | 20 (23.81) | 24.3611 |
| 2020's | 5 (5.95) | 2.80 |
| Authors | Studies |
|---|---|
| Nij Bijvank, SW | 2 |
| Hengst, M | 1 |
| Cornette, JC | 1 |
| Huigen, S | 1 |
| Winkelen, AV | 1 |
| Edens, MA | 2 |
| Duvekot, JJ | 4 |
| Kim, MK | 1 |
| Choe, KR | 1 |
| Jeong, DE | 1 |
| Lee, KN | 1 |
| Cho, I | 1 |
| Kim, HJ | 1 |
| Park, JY | 1 |
| Qi, H | 2 |
| Qin, J | 2 |
| Ren, L | 2 |
| Li, L | 2 |
| Lan, L | 2 |
| Yan, Y | 2 |
| Gan, S | 2 |
| Zhang, Y | 2 |
| Breslin, N | 1 |
| Baptiste, C | 1 |
| Miller, R | 1 |
| Fuchs, K | 1 |
| Goffman, D | 1 |
| Gyamfi-Bannerman, C | 1 |
| D'Alton, M | 1 |
| Xiang, B | 1 |
| Grandjean, B | 1 |
| Guerci, P | 1 |
| Raft, J | 1 |
| Fuchs-Buder, T | 1 |
| Bouaziz, H | 1 |
| Feinshtein, V | 1 |
| Erez, O | 1 |
| Ben-Zvi, Z | 1 |
| Eshkoli, T | 1 |
| Sheizaf, B | 1 |
| Sheiner, E | 1 |
| Holcberg, G | 1 |
| Matsumura, H | 1 |
| Takagi, K | 1 |
| Seki, H | 2 |
| Ono, Y | 1 |
| Ichinose, S | 1 |
| Masuko, H | 1 |
| Fukatsu, M | 1 |
| Miyashita, A | 1 |
| Mera, A | 1 |
| Nooij, LS | 1 |
| Visser, S | 1 |
| Meuleman, T | 1 |
| Vos, P | 1 |
| Roelofs, R | 1 |
| de Groot, CJ | 1 |
| Zieleskiewicz, L | 1 |
| Boustiere, V | 1 |
| Bourgoin, A | 1 |
| Hammad, E | 1 |
| Leone, M | 1 |
| Bretelle, F | 1 |
| Cornette, J | 1 |
| Buijs, EA | 1 |
| Herzog, E | 1 |
| Roos-Hesselink, JW | 1 |
| Rizopoulos, D | 1 |
| Meima, M | 1 |
| Steegers, EA | 4 |
| Bejan-Angoulvant, T | 1 |
| Crochet, J | 1 |
| Jonville-Bera, AP | 1 |
| Melis, M | 1 |
| Cupelli, A | 1 |
| Sottosanti, L | 1 |
| Buccellato, E | 1 |
| Biagi, C | 1 |
| Vaccheri, A | 1 |
| Motola, D | 1 |
| Bijvank, SW | 1 |
| Visser, W | 3 |
| Roofthooft, DW | 2 |
| Vulto, AG | 3 |
| Hanff, LM | 3 |
| Diemunsch, P | 2 |
| Garcia, V | 1 |
| Lyons, G | 1 |
| Pottecher, J | 1 |
| Emmanuel, S | 1 |
| Berdai, MA | 1 |
| Labib, S | 1 |
| Harandou, M | 1 |
| Archer, TL | 1 |
| Knape, K | 1 |
| Liles, D | 1 |
| Wheeler, AS | 1 |
| Carter, B | 1 |
| Pollex, E | 1 |
| Lubetsky, A | 1 |
| Koren, G | 1 |
| Philippe, HJ | 1 |
| Le Trong, A | 1 |
| Pigeau, H | 1 |
| Demeure, D | 1 |
| Desjars, P | 1 |
| Esbelin, J | 1 |
| Caroit, Y | 1 |
| Winer, N | 1 |
| Tixier, H | 1 |
| Feyeux, C | 1 |
| Girod, S | 1 |
| Thouvenot, S | 1 |
| Morisse, M | 1 |
| Douvier, S | 1 |
| Sagot, P | 1 |
| Perbet, S | 1 |
| Constantin, JM | 1 |
| Bolandard, F | 1 |
| Vignaud, M | 1 |
| Gallot, D | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Treatment of Severe Hypertension During Pre-Eclampsia.A Preliminary Equivalence Study Between URAPIDIL and NICARDIPINE[NCT00409253] | Phase 3 | 72 participants (Anticipated) | Interventional | 2007-06-30 | Recruiting | ||
| Phase 2 Study of Clinical Utility of Combination Tocolysis in Preterm Labor[NCT01429545] | Phase 2 | 110 participants (Actual) | Interventional | 2007-04-30 | Completed | ||
| Randomized Double-Blinded Trial of Magnesium Sulfate Tocolysis Versus Nifedipine Tocolysis in Women With Preterm Labor Between 24 to 32 6/7 Weeks' Gestation[NCT00306462] | 33 participants (Actual) | Interventional | 2006-03-31 | Terminated (stopped due to No enrollment in past year, lack of interest) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 reviews available for nicardipine and Pregnancy
| Article | Year |
|---|---|
The optimal treatment of severe hypertension in pregnancy: update of the role of nicardipine.
Topics: Antihypertensive Agents; Female; Humans; Hypertension; Hypotension; Infant, Newborn; Labetalol; Nica | 2014 |
[Calcium channel blockers pharmacology and their use as tocolytics].
Topics: Adult; Calcium Channel Blockers; Female; Humans; Nicardipine; Nifedipine; Obstetric Labor, Premature | 2015 |
Pharmacotherapeutic options for the treatment of preeclampsia.
Topics: Female; Humans; Hydralazine; Magnesium Sulfate; Nicardipine; Nifedipine; Nitroprusside; Pre-Eclampsi | 2009 |
Acute antihypertensive therapy in pregnancy-induced hypertension: is nicardipine the answer?
Topics: Acute Disease; Blood Pressure Determination; Calcium Channel Blockers; Dose-Response Relationship, D | 2009 |
[Intrahospital management of women with preeclampsia].
Topics: Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents; Antihypertensive Agents; Female; Fetal Mon | 2010 |
Nicardipine for the treatment of severe hypertension in pregnancy: a review of the literature.
Topics: Antihypertensive Agents; Female; Humans; Hypertension, Pregnancy-Induced; Nicardipine; Pregnancy; Re | 2010 |
Intra-arterial nicardipine for the treatment of cerebral vasospasm in postpartum cerebral angiopathy: a case study and review of literature.
Topics: Adult; Brain; Female; Humans; Injections, Intra-Arterial; Magnetic Resonance Angiography; Magnetic R | 2011 |
Pharmacokinetics of tocolytic agents.
Topics: Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic | 2004 |
Pathophysiology and medical management of systemic hypertension in preeclampsia.
Topics: Adrenergic beta-Antagonists; Aspirin; Calcium; Calcium Channel Blockers; Cerebral Hemorrhage; Female | 2006 |
The diagnosis and management of hypertensive crises.
Topics: Antihypertensive Agents; Aortic Aneurysm; Aortic Dissection; Clonidine; Diazoxide; Enalaprilat; Fema | 2000 |
10 trials available for nicardipine and Pregnancy
| Article | Year |
|---|---|
Ketanserin versus dihydralazine for the treatment of severe hypertension in early-onset preeclampsia: a double blind randomized controlled trial.
Topics: Adult; Antihypertensive Agents; Dihydralazine; Double-Blind Method; Female; Gestational Age; Hospita | 2015 |
Urapidil versus nicardipine in preeclamptic toxaemia: A randomised feasibility study.
Topics: Antihypertensive Agents; Blood Pressure; Feasibility Studies; Female; Humans; Infant, Newborn; Nicar | 2015 |
Nicardipine versus salbutamol in the treatment of premature labor: comparison of their efficacy and side effects.
Topics: Adult; Albuterol; Female; Humans; Nicardipine; Obstetric Labor, Premature; Pregnancy; Prospective St | 2008 |
Short-term treatment of severe hypertension of pregnancy: prospective comparison of nicardipine and labetalol.
Topics: Adult; Antihypertensive Agents; Female; Humans; Hypertension; Labetalol; Nicardipine; Pre-Eclampsia; | 2002 |
Nicardipine versus metoprolol in the treatment of hypertension during pregnancy: a randomized comparative trial.
Topics: Adult; Birth Weight; Blood Pressure; Cesarean Section; Drug Administration Schedule; Female; Humans; | 1994 |
Nicardipine treatment of hypertension during pregnancy.
Topics: Administration, Oral; Adult; Blood Pressure; Female; Fetus; Heart Rate; Heart Rate, Fetal; Humans; H | 1993 |
Nicardipine versus salbutamol in the treatment of premature labor. A prospective randomized study.
Topics: Adult; Albuterol; Calcium Channel Blockers; Female; Follow-Up Studies; Humans; Nicardipine; Obstetri | 1997 |
Oral nicardipine versus intravenous magnesium sulfate for the treatment of preterm labor.
Topics: Administration, Oral; Adult; Female; Humans; Infusions, Intravenous; Magnesium Sulfate; Nicardipine; | 1999 |
Intravenous nicardipine for severe hypertension in pre-eclampsia--effects of an acute treatment on mother and foetus.
Topics: Acute Disease; Adult; Analysis of Variance; Antihypertensive Agents; Blood Pressure; Drug Administra | 1999 |
Long-term treatment with nicardipine for severe pre-eclampsia.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Drug Administration Schedule; Female; Gestational Ag | 2002 |
64 other studies available for nicardipine and Pregnancy
| Article | Year |
|---|---|
Nicardipine for treating severe antepartum hypertension during pregnancy: Nine years of experience in more than 800 women.
Topics: Antihypertensive Agents; Blood Pressure; Cesarean Section; Female; Humans; Hypertension; Hypotension | 2022 |
Use of continuous infusion of nicardipine to control persistent postpartum hypertension: A retrospective study.
Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Hypertension; Labetalol; Nicar | 2022 |
Efficacy of low-dose nicardipine for emergent treatment of severe postpartum hypertension in maternal intensive care units: An observational study.
Topics: Administration, Intravenous; Adult; Blood Pressure; Calcium Channel Blockers; Female; Humans; Hypert | 2020 |
Coronavirus disease 2019 in pregnancy: early lessons.
Topics: Acute Kidney Injury; Adult; Anesthesia, General; Anti-Bacterial Agents; Antihypertensive Agents; Azi | 2020 |
Intra-arterial versus oscillometric blood pressure measurements in women with severe peripartum hypertension undergoing urgent treatment with nicardipine: An observational study.
Topics: Adult; Antihypertensive Agents; Arterial Pressure; Atrial Pressure; Blood Pressure; Blood Pressure D | 2021 |
[Sugammadex and profound rocuronium neuromuscular blockade induced by magnesium sulphate].
Topics: Abortion, Therapeutic; Acetylcholine; Adult; Androstanols; Anesthesia, General; Calcium Signaling; E | 2013 |
Cannabidiol enhances xenobiotic permeability through the human placental barrier by direct inhibition of breast cancer resistance protein: an ex vivo study.
Topics: Analysis of Variance; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette | 2013 |
Placental transfer of intravenous nicardipine and disposition into breast milk during the control of hypertension in women with pre-eclampsia.
Topics: Adult; Antihypertensive Agents; Female; Fetal Blood; Humans; Infant, Newborn; Milk, Human; Nicardipi | 2014 |
Nicardipine and preterm labour: pulmonary oedema.
Topics: Calcium Channel Blockers; Female; Humans; Infant, Newborn; Nicardipine; Obstetric Labor, Premature; | 2014 |
Nicardipine-associated pulmonary edema in a parturient: use of chest ultrasound.
Topics: Adult; Calcium Channel Blockers; Female; Humans; Nicardipine; Obstetric Labor, Premature; Pregnancy; | 2014 |
Hemodynamic effects of intravenous nicardipine in severely pre-eclamptic women with a hypertensive crisis.
Topics: Administration, Intravenous; Adolescent; Adult; Antihypertensive Agents; Cardiac Output; Echocardiog | 2016 |
Off-label use of nicardipine as tocolytic and acute pulmonary oedema: a post-marketing analysis of adverse drug reaction reports in EudraVigilance.
Topics: Acute Disease; Administration, Intravenous; Administration, Oral; Adult; Adverse Drug Reaction Repor | 2015 |
Prolonged neuromuscular block in a preeclamptic patient induced by magnesium sulfate.
Topics: Adult; Anesthesia, General; Cesarean Section; Female; HELLP Syndrome; Humans; Magnesium Sulfate; Neo | 2016 |
The hemodynamics of oxytocin and other vasoactive agents during neuraxial anesthesia for cesarean delivery: findings in six cases.
Topics: Adult; Anesthesia, Epidural; Cesarean Section; Female; Hemodynamics; Humans; Monitoring, Intraoperat | 2008 |
The role of placental breast cancer resistance protein in the efflux of glyburide across the human placenta.
Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biologic | 2008 |
[Acute pulmonary edema occurred during tocolytic treatment using nicardipine in a twin pregnancy. Report of three cases].
Topics: Adult; Diagnosis, Differential; Female; Humans; Nicardipine; Obstetric Labor, Premature; Pregnancy; | 2009 |
Acute voluntary intoxication with selective serotonin reuptake inhibitors during the third trimester of pregnancy: therapeutic management of mother and fetus.
Topics: Adrenal Cortex Hormones; Adult; Antidotes; Calcium Channel Blockers; Charcoal; Citalopram; Depressio | 2008 |
[Non-invasive ventilation for pulmonary edema associated with tocolytic agents during labour for a twin pregnancy].
Topics: Adult; Apgar Score; Delivery, Obstetric; Female; Humans; Infant, Newborn; Nicardipine; Nifedipine; P | 2008 |
Isoflurane enhances spontaneous Ca(2+) oscillations in developing rat hippocampal neurons in vitro.
Topics: Anesthetics, Inhalation; Animals; Bicuculline; Calcium Channel Blockers; Calcium Channels, L-Type; C | 2009 |
Overlapping features of eclampsia and postpartum angiopathy.
Topics: Adult; Cerebrovascular Disorders; Eclampsia; Female; Headache; Humans; Methylprednisolone; Nicardipi | 2009 |
Comparison between atosiban and nicardipine in inducing hypotension during in-utero transfers for threatening premature delivery.
Topics: Adult; Antihypertensive Agents; Case-Control Studies; Female; France; Humans; Hypotension, Controlle | 2010 |
[Nifedipine or nicardipine in management of threatened preterm delivery: an observational population-based study].
Topics: Adult; Calcium Channel Blockers; Female; France; Humans; Nicardipine; Nifedipine; Pregnancy; Prematu | 2010 |
[Comparison of the rate of maternal complications of nifedipine and nicardipine in cases of preterm labor: historical study on two consecutive periods].
Topics: Adult; Calcium Channel Blockers; Female; France; Humans; Nicardipine; Nifedipine; Obstetric Labor, P | 2012 |
[Complications of association magnesium sulfate with nicardipine during preeclampsia: report of 2 cases].
Topics: Adolescent; Adult; Calcium Channel Blockers; Cesarean Section; Depression, Chemical; Drug Interactio | 2012 |
Successful management of aortic dissection in a patient with Marfan syndrome during pregnancy.
Topics: Adult; Aortic Aneurysm; Aortic Dissection; Blood Pressure; Calcium Channel Blockers; Coronary Angiog | 2013 |
In vitro study of tocolytic effect of rofecoxib, a specific cyclo-oxygenase 2 inhibitor. Comparison and combination with other tocolytic agents.
Topics: Analysis of Variance; Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cycl | 2002 |
The vasodilatory effects of hydralazine, nicardipine, nitroglycerin, and fenoldopam in the human umbilical artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Dopamine; Dose-Response Relation | 2003 |
[Therapeutics indications and prognosis of eclampsia at Dakar University Teaching Hospital].
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Antihypertensive Agents; Eclampsia; Female; Gestati | 2003 |
The in vitro effect of dual combinations of ritodrine, nicardipine and atosiban on contractility of pregnant rat myometrium.
Topics: Animals; Calcium Channel Blockers; Drug Combinations; Female; Myometrium; Nicardipine; Pregnancy; Pr | 2003 |
Acute pulmonary oedema during nicardipine therapy for premature labour; Report of five cases.
Topics: Adult; Diagnosis, Differential; Female; Humans; Nicardipine; Obstetric Labor, Premature; Pregnancy; | 2004 |
Pulmonary edema induced by calcium-channel blockade for tocolysis.
Topics: Adult; Calcium Channel Blockers; Female; Humans; Nicardipine; Pregnancy; Pulmonary Edema; Tocolysis | 2004 |
Nicardipine or labetalol as short-term treatment for severe hypertension of pregnancy.
Topics: Antihypertensive Agents; Female; Humans; Hypertension, Pregnancy-Induced; Labetalol; Nicardipine; Pr | 2004 |
Comment on the article "Acute pulmonary oedema during nicardipine therapy for premature labour. Report of five cases" by Vaast P., et al. [Eur J Obstet Gynecol Reprod Biol 2004;113:98-9].
Topics: Calcium Channel Blockers; Female; Humans; Nicardipine; Nifedipine; Obstetric Labor, Premature; Pregn | 2005 |
[Acute pulmonary edema during nicardipine and salbutamol therapy for preterm labor in twin pregnancy].
Topics: Adult; Albuterol; Female; Gestational Age; Humans; Nicardipine; Obstetric Labor, Premature; Pregnanc | 2005 |
Intravenous use of the calcium-channel blocker nicardipine as second-line treatment in severe, early-onset pre-eclamptic patients.
Topics: Adolescent; Adult; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Female; Fetus; | 2005 |
[Acute pulmonary edema during preterm labor: role of nicardipine tocolysis (three cases)].
Topics: Acute Disease; Adrenergic beta-Agonists; Adult; Calcium Channel Blockers; Drug Interactions; Female; | 2005 |
[Tocolysis with nifedipine: its use in current practice. Gynecol Obstet Fertil 2005;33:483-7].
Topics: Female; Humans; Nicardipine; Nifedipine; Obstetric Labor, Premature; Pregnancy; Pregnancy Outcome; P | 2006 |
Nicardipine in pre-eclamptic patients: placental transfer and disposition in breast milk.
Topics: Adolescent; Adult; Antihypertensive Agents; Calcium Channel Blockers; Female; Fetal Blood; Humans; I | 2007 |
[Pulmonary edema during calcium-channel blockers therapy: role of predisposing or pharmacologic factors?].
Topics: Adult; Calcium Channel Blockers; Diabetes Mellitus, Type 1; Diseases in Twins; Female; Fetofetal Tra | 2007 |
Comparison of the effects of nicardipine and nifedipine on isolated human myometrium.
Topics: Adult; Calcium Channel Blockers; Dinoprost; Female; Humans; Myometrium; Nicardipine; Nifedipine; Oxy | 1983 |
Deactivation of the uterus during normal and premature labor by the calcium antagonist nicardipine.
Topics: Animals; Calcium Channel Blockers; Female; Labor, Obstetric; Nicardipine; Nifedipine; Obstetric Labo | 1982 |
Inotropic effects of ryanodine and nicardipine on fetal, neonatal and adult guinea-pig myocardium.
Topics: Animals; Animals, Newborn; Calcium; Female; Guinea Pigs; Heart; Heart Atria; Heart Ventricles; In Vi | 1994 |
[Effects of calcium antagonists on prostaglandin E2 production in cultured human amnion cells].
Topics: Amnion; Calcium Channel Blockers; Cells, Cultured; Depression, Chemical; Diltiazem; Dinoprostone; Do | 1994 |
Role of extracellular calcium and calcium channels in the response of human placental venous smooth muscle to endothelin-1.
Topics: Adult; Calcium; Calcium Channels; Endothelins; Extracellular Space; Female; Humans; In Vitro Techniq | 1993 |
The effect of nicardipine on maternal and fetal hemodynamics and uterine blood flow in chronically instrumented pregnant goats.
Topics: Animals; Female; Fetus; Goats; Hemodynamics; Monitoring, Physiologic; Nicardipine; Pregnancy; Region | 1993 |
[Anesthesia for cesarean section in a patient with intracranial A-V malformation].
Topics: Adult; Anesthesia, Epidural; Anesthesia, General; Anesthesia, Obstetrical; Cerebral Hemorrhage; Cesa | 1995 |
Accidental nicardipine overdosage without serious maternal or neonatal consequence.
Topics: Adult; Calcium Channel Blockers; Drug Overdose; Female; Heart Rate, Fetal; Humans; Hypertension; Inf | 1996 |
Effects of antihypertensive drugs on maternal and fetal hemodynamics and uterine blood flow in pregnant goats--comparison of nicardipine and labetalol.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Carbon Dioxide; Female; Fetal Blood; Fetus; Goats; | 1996 |
[Anesthesia for a patient with HELLP syndrome].
Topics: Adult; Alprostadil; Anesthesia, General; Anesthesia, Obstetrical; Cesarean Section; Female; Fentanyl | 1996 |
Propofol anesthesia for cesarean section successfully managed in a patient with moyamoya disease.
Topics: Adult; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Intravenous; Anesthesia, Obstetrical; | 1998 |
[Anesthetic management for emergency cesarean section in a patient with intracranial hemorrhage due to ruptured arteriovenous malformation].
Topics: Adult; Anesthesia, General; Anesthesia, Obstetrical; Cerebral Hemorrhage; Cesarean Section; Emergenc | 1999 |
Anesthetic management for pheochromocytoma resection using spinal cord stimulation and intravenous nicardipine--a case report.
Topics: Adrenal Gland Neoplasms; Adult; Anesthesia; Blood Pressure; Calcium Channel Blockers; Female; Humans | 1999 |
Augmentation and suppression of action potentials by estradiol in the myometrium of pregnant rat.
Topics: Action Potentials; Animals; Calcium Channels; Estradiol; Female; In Vitro Techniques; Muscle, Smooth | 1999 |
The effect of acute and chronic antihypertensive therapy on maternal and fetoplacental Doppler velocimetry.
Topics: Blood Pressure; Brachial Artery; Female; Fetus; Humans; Hypertension; Infant, Newborn; Nicardipine; | 1992 |
Effects of endothelins, Bay K 8644 and other oxytocics in non-pregnant and late pregnant rat isolated uterus.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1991 |
Effect of vasoconstrictor and vasodilator on isolated human umbilical vein.
Topics: Female; Humans; In Vitro Techniques; Nicardipine; Oxytocin; Pregnancy; Serotonin; Umbilical Veins; V | 1991 |
Characterization of membrane calcium channels in nonpregnant and pregnant human uterus.
Topics: Adult; Binding Sites; Calcium Channels; Cell Membrane; Female; Humans; Middle Aged; Myometrium; Nica | 1989 |
Ovine fetal cardiorespiratory response to nicardipine.
Topics: Animals; Blood Pressure; Female; Fetus; Heart Rate; Heart Rate, Fetal; Nicardipine; Pregnancy; Sheep | 1989 |
Fetal vascular responses to maternal nicardipine administration in the hypertensive ewe.
Topics: Angiotensin II; Animals; Blood Gas Analysis; Female; Fetal Blood; Fetal Heart; Hypertension; Nicardi | 1989 |
Placental vascular responses to nicardipine in the hypertensive ewe.
Topics: Angiotensin II; Animals; Female; Hypertension; Nicardipine; Placenta; Pregnancy; Pregnancy Complicat | 1989 |
Effects of calcium entry blocker (nicardipine) tocolysis in rhesus macaques: fetal plasma concentrations and cardiorespiratory changes.
Topics: Animals; Female; Fetal Blood; Fetus; Macaca mulatta; Maternal-Fetal Exchange; Nicardipine; Obstetric | 1987 |
Cardiovascular and uterine blood flow changes during nicardipine HCl tocolysis in the rabbit.
Topics: Animals; Blood Pressure; Cardiac Output; Cardiovascular System; Female; Nicardipine; Placenta; Pregn | 1987 |
Cardiovascular and tocolytic effects of nicardipine HCl in the pregnant rabbit: comparison with ritodrine HCl.
Topics: Animals; Blood Pressure; Cardiovascular System; Dose-Response Relationship, Drug; Female; Heart Rate | 1987 |
Effect of nicardipine HCl on prematurely induced uterine activity in the pregnant rabbit.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Electromyograph | 1985 |