nicardipine has been researched along with Pheochromocytoma in 20 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Calcium channel blockade with nicardipine (NC) is an alternative to phenoxybenzamine (PB) preparation for resection of a pheochromocytoma." | 7.78 | Utility of oral nicardipine and magnesium sulfate infusion during preparation and resection of pheochromocytomas. ( Doherty, GM; Fox, AC; Gauger, PG; Laird, AM; Miller, BS; Siddiqi, HK; Yang, HY, 2012) |
| " Blood pressure was maintained by bolus administration of nicardipine for the removal of pheochromocytoma." | 7.70 | Anesthetic management for pheochromocytoma resection using spinal cord stimulation and intravenous nicardipine--a case report. ( Hanzawa, K; Motoyama, Y; Shiraishi, M, 1999) |
| "Four patients underwent surgical removal of pheochromocytoma under balanced anesthesia with fentanyl, sevoflurane and epidural anesthesia combined with continuous infusion of nicardipine and nitroglycerin." | 7.68 | [Anesthetic management of patients with pheochromocytoma for adrenalectomy using balanced anesthesia with continuous infusion of nicardipine and nitroglycerin]. ( Moriwaki, K; Mukaida, K; Sanuki, M; Sato, N; Yuge, O, 1993) |
| "Calcium channel blockade with nicardipine (NC) is an alternative to phenoxybenzamine (PB) preparation for resection of a pheochromocytoma." | 3.78 | Utility of oral nicardipine and magnesium sulfate infusion during preparation and resection of pheochromocytomas. ( Doherty, GM; Fox, AC; Gauger, PG; Laird, AM; Miller, BS; Siddiqi, HK; Yang, HY, 2012) |
| " Nicardipine provides a good control of vasoconstriction during phaeochromocytoma surgery with limited risk of serious hypotension after tumour removal." | 3.70 | Haemodynamic heterogeneity and treatment with the calcium channel blocker nicardipine during phaeochromocytoma surgery. ( Colson, P; Dareau, S; Mann, C; Ribstein, J; Ryckwaert, F, 1998) |
| " Blood pressure was maintained by bolus administration of nicardipine for the removal of pheochromocytoma." | 3.70 | Anesthetic management for pheochromocytoma resection using spinal cord stimulation and intravenous nicardipine--a case report. ( Hanzawa, K; Motoyama, Y; Shiraishi, M, 1999) |
| "Four patients underwent surgical removal of pheochromocytoma under balanced anesthesia with fentanyl, sevoflurane and epidural anesthesia combined with continuous infusion of nicardipine and nitroglycerin." | 3.68 | [Anesthetic management of patients with pheochromocytoma for adrenalectomy using balanced anesthesia with continuous infusion of nicardipine and nitroglycerin]. ( Moriwaki, K; Mukaida, K; Sanuki, M; Sato, N; Yuge, O, 1993) |
| "The inhibitory effect of nicardipine, a potent Ca2+ channel blocker in muscular cells, on the Ca2+ channel of clonal rat pheochromocytoma cells (PC12h) and cultured rat adrenal medullary cells was studied during the neuronal differentiation mediated by nerve growth factor (NGF)." | 3.67 | Neuronal differentiation of Ca2+ channel by nerve growth factor. ( Hatanaka, H; Takahashi, M; Tsukui, H, 1985) |
| "This study investigates the role of nicardipine hydrochloride in preoperative and intraoperative blood pressure control and intraoperative catecholamines (norepinephrine and epinephrine) release in 10 patients undergoing pheochromocytoma resection." | 3.67 | Exclusive use of calcium channel blockers in preoperative and intraoperative control of pheochromocytomas: hemodynamics and free catecholamine assays in ten consecutive patients. ( Carnaille, B; Cecat, P; Petillot, P; Proye, C; Racadot, N; Sautier, M; Thevenin, D; Verin, P, 1989) |
| "Nicardipine, one of the dihydropyridine derivatives, in a nanomolar concentration range suppressed the high K+ -induced neurotransmitter release from cultured neuronal cells (chick embryonic neural retina cells and clonal rat pheochromocytoma cells)." | 3.66 | Dihydropyridines as potent calcium channel blockers in neuronal cells. ( Ogura, A; Takahashi, M, 1983) |
| "Nicardipine was used to control hypertensive episodes." | 1.27 | Blood glucose control by an artificial endocrine pancreas in a patient with phaeochromocytoma. ( Hamaji, M; Kawamori, R; Kawashima, Y; Mashimo, T; Miyata, M; Nakao, K; Shichiri, M, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (35.00) | 18.7374 |
| 1990's | 8 (40.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fukagawa, H | 1 |
| Hashiguchi, M | 1 |
| Ayabe, Y | 1 |
| Ando, T | 1 |
| Nakamura, K | 1 |
| Siddiqi, HK | 1 |
| Yang, HY | 1 |
| Laird, AM | 1 |
| Fox, AC | 1 |
| Doherty, GM | 1 |
| Miller, BS | 1 |
| Gauger, PG | 1 |
| Henry, A | 1 |
| Charpiat, B | 1 |
| Vial, T | 1 |
| Franchini, S | 1 |
| Cuilleret, FJ | 1 |
| Milon, H | 1 |
| Lebuffe, G | 1 |
| Dosseh, ED | 1 |
| Tek, G | 1 |
| Tytgat, H | 1 |
| Moreno, S | 1 |
| Tavernier, B | 3 |
| Vallet, B | 1 |
| Proye, CA | 1 |
| Ogura, A | 2 |
| Takahashi, M | 3 |
| Sanuki, M | 1 |
| Yuge, O | 1 |
| Sato, N | 1 |
| Moriwaki, K | 1 |
| Mukaida, K | 1 |
| Koizumi, S | 1 |
| Nakazawa, K | 1 |
| Inoue, K | 1 |
| Proye, C | 3 |
| Scherpereel, P | 3 |
| Combemale, F | 1 |
| Carnaille, B | 2 |
| Hautier, MB | 1 |
| Thevenot, A | 1 |
| Colson, P | 2 |
| Ryckwaert, F | 1 |
| Ribstein, J | 2 |
| Mann, C | 1 |
| Dareau, S | 1 |
| Shiraishi, M | 1 |
| Hanzawa, K | 1 |
| Motoyama, Y | 1 |
| Atallah, F | 1 |
| Bastide-Heulin, T | 1 |
| Soulié, M | 1 |
| Crouzil, F | 1 |
| Galiana, A | 1 |
| Samii, K | 1 |
| Virenque, C | 1 |
| Schettini, G | 1 |
| Meucci, O | 1 |
| Grimaldi, M | 1 |
| Florio, T | 1 |
| Landolfi, E | 1 |
| Scorziello, A | 1 |
| Ventra, C | 1 |
| Chaptal, PA | 1 |
| Mimran, A | 1 |
| Roquefeuil, B | 1 |
| Tsukui, H | 1 |
| Hatanaka, H | 1 |
| Thevenin, D | 2 |
| Cecat, P | 1 |
| Petillot, P | 2 |
| Verin, P | 1 |
| Sautier, M | 1 |
| Racadot, N | 2 |
| Grim, M | 1 |
| Messiant, F | 1 |
| Arai, T | 1 |
| Hatano, Y | 1 |
| Ishida, H | 1 |
| Mori, K | 1 |
| Hamaji, M | 1 |
| Miyata, M | 1 |
| Kawamori, R | 1 |
| Shichiri, M | 1 |
| Mashimo, T | 1 |
| Nakao, K | 1 |
| Kawashima, Y | 1 |
1 trial available for nicardipine and Pheochromocytoma
| Article | Year |
|---|---|
[Exclusive use of calcium channel blockers and cardioselective beta-blockers in the pre- and per-operative management of pheochromocytomas. 70 cases].
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Calciu | 1998 |
19 other studies available for nicardipine and Pheochromocytoma
| Article | Year |
|---|---|
[Anesthetic management of undiagnosed pheochromocytoma: a case report].
Topics: Adrenal Gland Neoplasms; Anesthesia; Antihypertensive Agents; Humans; Hypertension; Intraoperative C | 2008 |
Utility of oral nicardipine and magnesium sulfate infusion during preparation and resection of pheochromocytomas.
Topics: Administration, Oral; Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Adult; Aged; Antihypert | 2012 |
Pheochromocytoma unmasked by amisulpride and tiapride.
Topics: Adult; Amisulpride; Antipsychotic Agents; Calcium Channel Blockers; Headache; Humans; Hypertension; | 2005 |
The effect of calcium channel blockers on outcome following the surgical treatment of phaeochromocytomas and paragangliomas.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Blood Pressure; Calcium Channel Blockers; Chi-Squa | 2005 |
Differential effect of a dihydropyridine derivative to Ca2+ entry pathways in neuronal preparations.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Cerebral Cortex; Clone Cells; Do | 1984 |
Dihydropyridines as potent calcium channel blockers in neuronal cells.
Topics: Adrenal Gland Neoplasms; Animals; Calcium; Calcium Channel Blockers; Calcium Chloride; Chick Embryo; | 1983 |
[Anesthetic management of patients with pheochromocytoma for adrenalectomy using balanced anesthesia with continuous infusion of nicardipine and nitroglycerin].
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Anesthesia, Epidural; Female; Humans; Infusions, Intr | 1993 |
Inhibition by Zn2+ of uridine 5'-triphosphate-induced Ca(2+)-influx but not Ca(2+)-mobilization in rat phaeochromocytoma cells.
Topics: Adenosine Triphosphate; Adrenal Gland Neoplasms; Animals; Calcium; Cells, Cultured; Dopamine; Dose-R | 1995 |
[Hemodynamic management in the surgery of pheochromocytoma].
Topics: Adrenal Gland Neoplasms; Antihypertensive Agents; Hemodynamics; Humans; Nicardipine; Pheochromocytom | 1996 |
Haemodynamic heterogeneity and treatment with the calcium channel blocker nicardipine during phaeochromocytoma surgery.
Topics: Adrenal Gland Neoplasms; Adult; Aged; Arrhythmias, Cardiac; Calcium Channel Blockers; Female; Hemody | 1998 |
Anesthetic management for pheochromocytoma resection using spinal cord stimulation and intravenous nicardipine--a case report.
Topics: Adrenal Gland Neoplasms; Adult; Anesthesia; Blood Pressure; Calcium Channel Blockers; Female; Humans | 1999 |
Haemodynamic changes during retroperitoneoscopic adrenalectomy for phaeochromocytoma.
Topics: Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Female; Hemodynamics; Humans; Intraoperat | 2001 |
Dihydropyridine modulation of voltage-activated calcium channels in PC12 cells: effect of pertussis toxin pretreatment.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1991 |
[Pre- and postoperative antihypertensive treatment with calcium antagonist in pheochromocytoma].
Topics: Adrenal Gland Neoplasms; Adult; Calcium Channel Blockers; Female; Hemodynamics; Humans; Hypertension | 1990 |
Neuronal differentiation of Ca2+ channel by nerve growth factor.
Topics: Adrenal Gland Neoplasms; Adrenal Medulla; Animals; Calcium; Cell Differentiation; Cell Line; Clone C | 1985 |
Exclusive use of calcium channel blockers in preoperative and intraoperative control of pheochromocytomas: hemodynamics and free catecholamine assays in ten consecutive patients.
Topics: Adrenal Gland Neoplasms; Adult; Blood Pressure; Epinephrine; Female; Heart Rate; Hemodynamics; Human | 1989 |
[Surgery for pheochromocytoma: preparation and control of peroperative hemodynamic variations with injectable nicardipine].
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Female; Hemodynamics; Humans; Intraoperative Perio | 1989 |
Use of nicardipine in the anesthetic management of pheochromocytoma.
Topics: Adult; Anesthesia, Local; Blood Pressure; Cardiac Output; Epinephrine; Female; Fentanyl; Heart Rate; | 1986 |
Blood glucose control by an artificial endocrine pancreas in a patient with phaeochromocytoma.
Topics: Adrenal Gland Neoplasms; Blood Glucose; Calcium Channel Blockers; Catecholamines; Diabetes Mellitus, | 1985 |