Page last updated: 2024-11-01

nicardipine and Pain

nicardipine has been researched along with Pain in 8 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"Three calcium (Ca) channel antagonists were administered to healthy adult volunteers by iontophoresis alone or in combination with lidocaine to study their effects on the pain threshold."5.08The effect of calcium channel antagonist administered by iontophoresis on the pain threshold. ( Honda, N; Miyagawa, A; Mizutani, A; Oyama, T; Taniguchi, K, 1995)
"We report a case of Cushing's disease revealed by recurrent rupture of Achilles tendon."1.35Spontaneous rupture of Achilles tendon and Cushing's disease. Case report. ( Batisse, M; Delorme, JP; Desbiez, F; Somda, F; Tauveron, I; Thieblot, P, 2008)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (62.50)18.2507
2000's2 (25.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baraldi, PG1
Preti, D1
Materazzi, S1
Geppetti, P1
Batisse, M1
Somda, F1
Delorme, JP1
Desbiez, F1
Thieblot, P1
Tauveron, I1
Shafton, AD1
Furness, JB1
Ferens, D1
Bogeski, G1
Koh, SL1
Lean, NP1
Kitchener, PD1
Taniguchi, K1
Miyagawa, A1
Mizutani, A1
Honda, N1
Oyama, T1
Hodoğluğil, U1
Güney, HZ1
Savran, B1
Güzey, C1
Görgün, CZ1
Zengil, H1
Yamashiro, K1
Tomiyama, N1
Ishida, A1
Terada, Y1
Mukawa, J1
Yoshii, Y1
Tasker, RR1
Albe-Fessard, D1
Ferri, C1
Cecchetti, R1
Cini, G1
Gambini, I1
La Civita, L1
Bernini, L1
Bombardieri, S1
Pasero, G1
Gürdal, H1
Sara, Y1
Tulunay, FC1

Reviews

1 review available for nicardipine and Pain

ArticleYear
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
    Journal of medicinal chemistry, 2010, Jul-22, Volume: 53, Issue:14

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Asthma; Humans; Ion Channel Gating; Neurons; Pain; Pe

2010

Trials

2 trials available for nicardipine and Pain

ArticleYear
The effect of calcium channel antagonist administered by iontophoresis on the pain threshold.
    Acta anaesthesiologica Belgica, 1995, Volume: 46, Issue:2

    Topics: Adult; Calcium Channel Blockers; Diltiazem; Drug Combinations; Female; Humans; Iontophoresis; Lidoca

1995
Slow-releasing nicardipine in the treatment of Raynaud's phenomena without underlying diseases.
    Clinical rheumatology, 1992, Volume: 11, Issue:1

    Topics: Adult; Aged; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Middle Aged; Ni

1992

Other Studies

5 other studies available for nicardipine and Pain

ArticleYear
Spontaneous rupture of Achilles tendon and Cushing's disease. Case report.
    Annales d'endocrinologie, 2008, Volume: 69, Issue:6

    Topics: Absorptiometry, Photon; Achilles Tendon; Adrenalectomy; Adult; Diabetes Complications; Hormones; Hum

2008
The visceromotor responses to colorectal distension and skin pinch are inhibited by simultaneous jejunal distension.
    Pain, 2006, Volume: 123, Issue:1-2

    Topics: Abdominal Muscles; Afferent Pathways; Analgesia; Animals; Calcium Channel Blockers; Calcium Channels

2006
Temporal variation in the interaction between calcium channel blockers and morphine-induced analgesia.
    Chronobiology international, 1996, Volume: 13, Issue:3

    Topics: Analgesia; Animals; Calcium Channel Blockers; Circadian Rhythm; Diltiazem; Drug Synergism; Male; Mic

1996
Characteristics of neurons with high-frequency discharge in the central nervous system and their relationship to chronic pain. Experimental and clinical investigations.
    Stereotactic and functional neurosurgery, 1997, Volume: 68, Issue:1-4 Pt 1

    Topics: Animals; Calcium Channel Blockers; Chronic Disease; Denervation; Disease Models, Animal; Electric St

1997
Effects of calcium channel blockers on formalin-induced nociception and inflammation in rats.
    Pharmacology, 1992, Volume: 44, Issue:5

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Diltiazem; F

1992