nicardipine has been researched along with Osteosarcoma in 3 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study evaluates in osteosarcoma cells, the effects of a calcium channel inhibitor nicardipine in 24-hydroxylase activity and 45Ca desaturation curve in presence of 1,25-dihydroxycholecalciferol (1,25(OH)2D3)." | 3.67 | Calcium-transport in quiescent and 1,25-dihydroxycholecalciferol-stimulated human osteosarcoma cells. Role in 24 hydroxylase enhancement. ( Cancela, L; Ly, SY; Rebut-Bonneton, C, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ramachandra, M | 1 |
| Ambudkar, SV | 1 |
| Gottesman, MM | 1 |
| Pastan, I | 1 |
| Hrycyna, CA | 1 |
| Yamaguchi, DT | 1 |
| Green, J | 1 |
| Kleeman, CR | 1 |
| Muallem, S | 1 |
| Rebut-Bonneton, C | 1 |
| Ly, SY | 1 |
| Cancela, L | 1 |
3 other studies available for nicardipine and Osteosarcoma
| Article | Year |
|---|---|
Functional characterization of a glycine 185-to-valine substitution in human P-glycoprotein by using a vaccinia-based transient expression system.
Topics: 3T3 Cells; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; ATP Binding Cassette Transpor | 1996 |
Characterization of volume-sensitive, calcium-permeating pathways in the osteosarcoma cell line UMR-106-01.
Topics: Calcium; Cell Membrane Permeability; Cytosol; Diltiazem; Electric Conductivity; Kinetics; Lanthanum; | 1989 |
Calcium-transport in quiescent and 1,25-dihydroxycholecalciferol-stimulated human osteosarcoma cells. Role in 24 hydroxylase enhancement.
Topics: Calcitriol; Calcium; Cycloheximide; Cytochrome P-450 Enzyme System; Humans; Nicardipine; Osteosarcom | 1988 |