Page last updated: 2024-11-01

nicardipine and Neuromuscular Blockade

nicardipine has been researched along with Neuromuscular Blockade in 5 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Neuromuscular Blockade: The intentional interruption of transmission at the NEUROMUSCULAR JUNCTION by external agents, usually neuromuscular blocking agents. It is distinguished from NERVE BLOCK in which nerve conduction (NEURAL CONDUCTION) is interrupted rather than neuromuscular transmission. Neuromuscular blockade is commonly used to produce MUSCLE RELAXATION as an adjunct to anesthesia during surgery and other medical procedures. It is also often used as an experimental manipulation in basic research. It is not strictly speaking anesthesia but is grouped here with anesthetic techniques. The failure of neuromuscular transmission as a result of pathological processes is not included here.

Research Excerpts

ExcerptRelevanceReference
"The objective of this study was to identify the effects of nicardipine on neuromuscular blockade of rocuronium, such as the onset time and intubation conditions, using a nicardipine dose that attenuates cardiovascular responses during endotracheal intubation."9.22Effects of nicardipine on the onset time and intubation conditions of rocuronium-induced neuromuscular blockade. ( Chung, WS; Kim, YH; Ko, YK; Lee, JU; Lee, SY; Lim, CS; Park, SI, 2016)
" She developed a prolonged and deep neuromuscular blockade, which was antagonized three hours later with neostigmine."3.83Prolonged neuromuscular block in a preeclamptic patient induced by magnesium sulfate. ( Berdai, MA; Harandou, M; Labib, S, 2016)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Han, J1
Oh, AY1
Grandjean, B1
Guerci, P1
Raft, J1
Fuchs-Buder, T1
Bouaziz, H1
Lee, SY1
Kim, YH1
Ko, YK1
Park, SI1
Lee, JU1
Chung, WS1
Lim, CS1
Berdai, MA1
Labib, S1
Harandou, M1
Saitoh, Y1
Narumi, Y1
Fujii, Y1

Trials

2 trials available for nicardipine and Neuromuscular Blockade

ArticleYear
Effects of nicardipine on the onset time and intubation conditions of rocuronium-induced neuromuscular blockade.
    Journal of clinical anesthesia, 2016, Volume: 32

    Topics: Adolescent; Adult; Androstanols; Calcium Channel Blockers; Double-Blind Method; Drug Synergism; Fema

2016
Post-tetanic count and train-of-four responses during neuromuscular block produced by vecuronium and infusion of nicardipine.
    British journal of anaesthesia, 1999, Volume: 83, Issue:2

    Topics: Adult; Analysis of Variance; Anesthesia Recovery Period; Calcium Channel Blockers; Electric Stimulat

1999

Other Studies

3 other studies available for nicardipine and Neuromuscular Blockade

ArticleYear
Precipitation of sugammadex with nicardipine and labetalol: A laboratory research.
    Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:5

    Topics: Labetalol; Neuromuscular Blockade; Neuromuscular Nondepolarizing Agents; Nicardipine; Research; Suga

2023
[Sugammadex and profound rocuronium neuromuscular blockade induced by magnesium sulphate].
    Annales francaises d'anesthesie et de reanimation, 2013, Volume: 32, Issue:5

    Topics: Abortion, Therapeutic; Acetylcholine; Adult; Androstanols; Anesthesia, General; Calcium Signaling; E

2013
Prolonged neuromuscular block in a preeclamptic patient induced by magnesium sulfate.
    The Pan African medical journal, 2016, Volume: 25

    Topics: Adult; Anesthesia, General; Cesarean Section; Female; HELLP Syndrome; Humans; Magnesium Sulfate; Neo

2016