nicardipine has been researched along with Necrosis in 4 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was designed to investigate whether two L-type calcium antagonists, verapamil and nicardipine reduce the myocardial necrosis (infarct size) following ischemia and reperfusion." | 7.70 | [Comparison of effects of verapamil and those of nicardipine on myocardial ischemia and reperfusion injury: a study in an in situ rabbit model]. ( Furuya, M; Yoshida, K, 1999) |
| "This study was designed to investigate whether two L-type calcium antagonists, verapamil and nicardipine reduce the myocardial necrosis (infarct size) following ischemia and reperfusion." | 3.70 | [Comparison of effects of verapamil and those of nicardipine on myocardial ischemia and reperfusion injury: a study in an in situ rabbit model]. ( Furuya, M; Yoshida, K, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arora, S | 1 |
| Alfayoumi, F | 1 |
| Khawaja, AT | 1 |
| Dua, A | 1 |
| Srinivasan, V | 1 |
| Gradman, AH | 1 |
| Senoo, Y | 1 |
| Murakami, T | 1 |
| Kawakami, S | 1 |
| Teramoto, S | 1 |
| Nakamura, K | 1 |
| Hatakeyama, T | 1 |
| Furuta, S | 1 |
| Sakaki, S | 1 |
| Furuya, M | 1 |
| Yoshida, K | 1 |
1 trial available for nicardipine and Necrosis
| Article | Year |
|---|---|
Effect of intracoronary nicardipine on cardiac enzymes after elective percutaneous coronary intervention.
Topics: Angioplasty, Balloon, Coronary; Biomarkers; Calcium Channel Blockers; Coronary Artery Disease; Creat | 2009 |
3 other studies available for nicardipine and Necrosis
| Article | Year |
|---|---|
Changes in systemic redistribution of blood flow by vasodilators.
Topics: Animals; Blood Circulation; Blood Gas Analysis; Blood Pressure; Cardiac Output; Chlorpromazine; Dogs | 1984 |
The role of early Ca2+ influx in the pathogenesis of delayed neuronal death after brief forebrain ischemia in gerbils.
Topics: Animals; Autoradiography; Brain; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Cell Deat | 1993 |
[Comparison of effects of verapamil and those of nicardipine on myocardial ischemia and reperfusion injury: a study in an in situ rabbit model].
Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Disease Models, Animal; Myocardial Ischem | 1999 |