nicardipine has been researched along with Myocardial Ischemia in 8 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was designed to investigate whether two L-type calcium antagonists, verapamil and nicardipine reduce the myocardial necrosis (infarct size) following ischemia and reperfusion." | 7.70 | [Comparison of effects of verapamil and those of nicardipine on myocardial ischemia and reperfusion injury: a study in an in situ rabbit model]. ( Furuya, M; Yoshida, K, 1999) |
| "We assessed the efficacy of a continuous infusion of nicardipine and nitroglycerin in reducing the incidence and severity of perioperative myocardial ischemia during elective coronary artery bypass grafting procedures in a prospective, randomized, controlled study." | 5.09 | Antiischemic effects of nicardipine and nitroglycerin after coronary artery bypass grafting. ( Apostolidou, IA; Despotis, GJ; Hauptmann, EL; Hogue, CW; Lappas, DG; McCawley, CA; Skubas, NJ, 1999) |
| "This study was designed to investigate whether two L-type calcium antagonists, verapamil and nicardipine reduce the myocardial necrosis (infarct size) following ischemia and reperfusion." | 3.70 | [Comparison of effects of verapamil and those of nicardipine on myocardial ischemia and reperfusion injury: a study in an in situ rabbit model]. ( Furuya, M; Yoshida, K, 1999) |
| "The purpose of this study was to evaluate the effects of the chronic administration of a calcium channel blocker, nicardipine, on systolic and diastolic alterations occurring during myocardial stunning in isolated rabbit hearts." | 1.29 | Chronic administration of nicardipine attenuates myocardial stunning in isolated rabbit hearts. ( Cingolani, HE; Gelpi, RJ; Moreyra, AE; Mosca, SM, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tabouy, L | 1 |
| Chauvet-Monges, AM | 1 |
| Salducci, MD | 1 |
| Crevat, A | 1 |
| Moreyra, AE | 1 |
| Gelpi, RJ | 1 |
| Mosca, SM | 1 |
| Cingolani, HE | 1 |
| Furuya, Y | 1 |
| Atarashi, K | 1 |
| Tachibana, C | 1 |
| Kobayashi, N | 1 |
| Satoh, K | 1 |
| Ohe, Y | 1 |
| Amrani, M | 1 |
| Matta, A | 1 |
| Dion, RA | 1 |
| Pust, B | 1 |
| Surlan, M | 1 |
| Apostolidou, IA | 1 |
| Despotis, GJ | 2 |
| Hogue, CW | 2 |
| Skubas, NJ | 2 |
| McCawley, CA | 2 |
| Hauptmann, EL | 1 |
| Lappas, DG | 2 |
| Apostolidou, I | 1 |
| Bakola, A | 1 |
| Furuya, M | 1 |
| Yoshida, K | 1 |
2 trials available for nicardipine and Myocardial Ischemia
| Article | Year |
|---|---|
Antiischemic effects of nicardipine and nitroglycerin after coronary artery bypass grafting.
Topics: Aged; Coronary Artery Bypass; Coronary Disease; Dose-Response Relationship, Drug; Electrocardiograph | 1999 |
Effects of nicardipine and nitroglycerin on perioperative myocardial ischemia in patients undergoing coronary artery bypass surgery.
Topics: Calcium Channel Blockers; Coronary Artery Bypass; Female; Hemodynamics; Humans; Male; Middle Aged; M | 1999 |
6 other studies available for nicardipine and Myocardial Ischemia
| Article | Year |
|---|---|
Protective effect of some calcium antagonists against mitochondrial calcium injury.
Topics: Adenosine Triphosphate; Amlodipine; Animals; Antihypertensive Agents; Bepridil; Calcium Channel Bloc | 1994 |
Chronic administration of nicardipine attenuates myocardial stunning in isolated rabbit hearts.
Topics: Animals; Blood Pressure; Calcium; Free Radicals; Heart; Myocardial Contraction; Myocardial Ischemia; | 1994 |
[Comparison between diltiazem and nicardipine used during anesthesia for coronary revascularization].
Topics: Aged; Anesthesia, Inhalation; Depression, Chemical; Diltiazem; Female; Fentanyl; Hemodynamics; Human | 1994 |
Beneficial effect of nicardipine on perioperative myocardial ischemia.
Topics: Adult; Aged; Cardiac Surgical Procedures; Female; Humans; Intraoperative Complications; Male; Middle | 1993 |
Pre-PTCA detection of chronic but reversible postischemic myocardial dysfunction by nicardipine.
Topics: Administration, Oral; Adult; Aged; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Cinerad | 1998 |
[Comparison of effects of verapamil and those of nicardipine on myocardial ischemia and reperfusion injury: a study in an in situ rabbit model].
Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Disease Models, Animal; Myocardial Ischem | 1999 |