nicardipine has been researched along with Muscle Contraction in 154 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of nicardipine, a calcium channel blocker, on diaphragmatic fatigue were studied in 20 anaesthetized, mechanically ventilated dogs divided into two groups: control group (Group C, n = 10) and nicardipine group (Group N, n = 10)." | 7.69 | Nicardipine enhances diaphragmatic fatigue. ( Amaha, K; Fujii, Y; Toyooka, H, 1994) |
| " To evaluate relative contribution of Ca2+ entry through the L-type voltage-gated calcium channels and Ca2+ -induced Ca2+ -release (CICR) mechanisms in initiation of vascular smooth muscle contraction induced by P2XRs activation, we have applied P2X receptor agonist -meATP (10 microM) and measured changes in phasic isometric tension of endothelium-denuded mesenteric artery rings in the presence of antagonists IP3Rs (60 mcmol/l APB) or RyRs (100 mcmol/l tetracaine) combined with on-off modulation of the L-type calcium channels by nicardipine (5 microM)." | 3.75 | [Effects of modulators of calcium metabolism on mesenteric artery contractions during activation of P2X receptors in guinea-pig]. ( Bolton, TB; Buryĭ, VA; Hordiienko, DV; Sahach, VF; Sukhanova, KhIu, 2009) |
| "We studied the effects of hydralazine, nicardipine, nitroglycerin, and fenoldopam (a dopamine D1-agonist) on isolated human umbilical arteries (HUA) from patients classified as normotensive and with pregnancy-induced hypertension (PIH)." | 3.72 | The vasodilatory effects of hydralazine, nicardipine, nitroglycerin, and fenoldopam in the human umbilical artery. ( Arias, ME; Levy, JH; Sato, N; Szlam, F; Tanaka, KA; Tsuda, A, 2003) |
| " An L-type Ca2+ channel blocker, nicardipine, did not suppress the electrical field stimulation-induced smooth muscle contraction and did not alter the inhibitory effect of epinastine." | 3.70 | Effects of epinastine hydrochloride on cholinergic neuro-effector transmission in canine tracheal smooth muscle. ( Aizawa, H; Hara, N; Hirose, T; Inoue, H; Matsumoto, K; Nakano, H; Nishima, S; Takahashi, N, 1998) |
| "The effects of nicardipine, a calcium channel blocker, on diaphragmatic fatigue were studied in 20 anaesthetized, mechanically ventilated dogs divided into two groups: control group (Group C, n = 10) and nicardipine group (Group N, n = 10)." | 3.69 | Nicardipine enhances diaphragmatic fatigue. ( Amaha, K; Fujii, Y; Toyooka, H, 1994) |
| " Mitragynine (3-10 microM) did not show any effect on the smooth muscle contraction induced by acetylcholine or histamine." | 3.69 | Inhibitory effect of mitragynine, an alkaloid with analgesic effect from Thai medicinal plant Mitragyna speciosa, on electrically stimulated contraction of isolated guinea-pig ileum through the opioid receptor. ( Horie, S; Watanabe, K; Yamamoto, LT; Yano, S, 1997) |
| "We have assessed the potential antihypertensive effect of a new slow channel blocker, nicardipine, in a group of patients with essential hypertension." | 3.66 | The effect of a new calcium channel blocker nicardipine on 24-hour ambulatory blood pressure and the pressor response to isometric and dynamic exercise. ( Hornung, RS; Jones, RI; Raftery, EB; Sonecha, T, 1983) |
| "Cardiovascular diseases are a leading cause of hospitalizations and death in the United States and elsewhere in the world." | 2.46 | Cardiovascular pharmacology: an update. ( Fox, CJ; Kaye, AD; Liu, H; Zhang, S, 2010) |
| "In nicardipine pretreated condition, the concentration-response curves for the negative inotropic effect of potassium channel blockers were shifted to the right by the increasing concentration of carbachol from 0." | 1.32 | Inhibitory effects of potassium channel blockers on carbachol-induced contraction in rat detrusor muscle. ( Ahn, SC; Oh, SJ, 2003) |
| " The dose-response curves for the effects of aminophylline in the presence of Ni2+ on Td and dT/dt max during direct single-pulse stimulation were significantly shifted to the right." | 1.29 | Some new evidence on antifatigue action of aminophylline on the isolated hemidiaphragm of the rat. ( Prostran, M; Todorović, Z; Varagić, VM, 1993) |
| "Calcium gluconate (300 mg) was then infused in all animals, and reversal of neuromuscular blockade was measured using the nerve stimulator to compare the saline- and nicardipine-treated groups." | 1.29 | Effect of nicardipine on the reversal of magnesium toxicity by calcium gluconate in nonpregnant rabbits. ( Holbrook, RH; Moir, M, 1993) |
| "In ryanodine-treated smooth muscle cells, Y-26763 hyperpolarized the membrane and potently inhibited the membrane depolarization induced by Hist." | 1.29 | Effect of membrane hyperpolarization induced by a K+ channel opener on histamine-induced Ca2+ mobilization in rabbit arterial smooth muscle. ( Itoh, T; Suzuki, A; Suzuki, H; Watanabe, Y, 1996) |
| " Tolerance of the antihypertensive effect of TC-81 in daily dosing for 2 weeks and the rebound phenomena after discontinuance of the treatment were not observed in RHD." | 1.28 | Antihypertensive effect of the new dihydropyridine calcium antagonist (+-)-3-(benzylmethylamino)-2,2-dimethylpropyl methyl 4-(2-fluoro-5-nitrophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedica rbo xylate hydrochloride in dogs. ( Aoki, K; Kishimoto, T; Naruchi, T; Okamiya, Y; Sunakawa, K; Takeshita, T; Tanabe, H, 1992) |
| "Caffeine contracture was inhibited by the calcium antagonists at 20 degrees C." | 1.28 | Dependence of contractile responses by some calcium antagonists on external calcium in the skeletal muscle. ( Hatae, J; Kawata, H, 1990) |
| " Further, the decrease of the vascular tone induced by long-term administration of the angiotensin converting enzyme inhibitor may be due to a reduction of increased [Ca2+]i in SHR." | 1.28 | Cytosolic free calcium of aorta in hypertensive rats. Chronic inhibition of angiotensin converting enzyme. ( Ikeda, M; Karaki, H; Koike, H; Ozaki, H; Sada, T; Sato, K, 1990) |
| "The relaxant effects of five organic calcium antagonists (nicardipine, diltiazem, PY 108068, verapamil and bepridil) on guinea-pig isolated trachea were tested against contractions induced by acetylcholine, histamine, 5-hydroxytryptamine, potassium chloride (KCl) and tetraethylammonium (TEA) in a medium containing the normal amount of calcium and against calcium dose-response curves in a calcium-free, potassium-enriched medium." | 1.27 | Effects of five different organic calcium antagonists on guinea-pig isolated trachea. ( Advenier, C; Cerrina, J; Duroux, P; Floch, A; Renier, A, 1984) |
| " Nicardipine at 10(-7) mol/l shifted to the right the dose-response curve for Ca of the phasic contraction evoked by electrical stimulation with an alternating current, and at higher concentration it reduced the maximum tension and slope of the dose-response curve." | 1.27 | Calcium antagonistic properties of nicardipine, a dihydropyridine derivative assessed in isolated cerebral arteries and cardiac muscle. ( Ishii, K; Kato, H; Kurihara, J; Miyajima, Y; Nakayama, K, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 44 (28.57) | 18.7374 |
| 1990's | 75 (48.70) | 18.2507 |
| 2000's | 30 (19.48) | 29.6817 |
| 2010's | 4 (2.60) | 24.3611 |
| 2020's | 1 (0.65) | 2.80 |
| Authors | Studies |
|---|---|
| Marciniak, G | 1 |
| Delgado, A | 1 |
| Leclerc, G | 1 |
| Velly, J | 1 |
| Decker, N | 1 |
| Schwartz, J | 1 |
| Yamamoto, K | 2 |
| Fujita, M | 1 |
| Tabashi, K | 1 |
| Kawashima, Y | 1 |
| Kato, E | 1 |
| Oya, M | 1 |
| Iso, T | 2 |
| Iwao, J | 1 |
| Chen, Q | 1 |
| Jiang, Z | 1 |
| Zhang, J | 2 |
| Cao, L | 1 |
| Chen, Z | 1 |
| Schwerdtfeger, LA | 1 |
| Ryan, EP | 1 |
| Tobet, SA | 1 |
| Daniel, EE | 3 |
| Eteraf, T | 1 |
| Sommer, B | 1 |
| Cho, WJ | 1 |
| Elyazbi, A | 1 |
| Aoshima, D | 1 |
| Murata, T | 1 |
| Hori, M | 2 |
| Ozaki, H | 5 |
| Sukhanova, KhIu | 1 |
| Buryĭ, VA | 1 |
| Sahach, VF | 1 |
| Bolton, TB | 1 |
| Hordiienko, DV | 1 |
| Roberts, RR | 1 |
| Ellis, M | 1 |
| Gwynne, RM | 1 |
| Bergner, AJ | 1 |
| Lewis, MD | 1 |
| Beckett, EA | 1 |
| Bornstein, JC | 1 |
| Young, HM | 1 |
| Liu, H | 1 |
| Fox, CJ | 1 |
| Zhang, S | 1 |
| Kaye, AD | 1 |
| Kitazawa, T | 1 |
| Hennig, GW | 1 |
| Smith, CB | 1 |
| O'Shea, DM | 1 |
| Smith, TK | 1 |
| Xi, Q | 1 |
| Ziogas, J | 1 |
| Roberts, JA | 1 |
| Evans, RJ | 1 |
| Angus, JA | 1 |
| Sato, N | 1 |
| Tanaka, KA | 1 |
| Szlam, F | 1 |
| Tsuda, A | 1 |
| Arias, ME | 1 |
| Levy, JH | 1 |
| Hirota, K | 1 |
| Hashiba, E | 1 |
| Yoshioka, H | 1 |
| Kabara, S | 1 |
| Matsuki, A | 2 |
| Fujii, Y | 4 |
| Miller, SM | 1 |
| Szurszewski, JH | 1 |
| El Sayah, M | 1 |
| Calixto, JB | 3 |
| Oh, SJ | 1 |
| Ahn, SC | 1 |
| Grumann Júnior, A | 1 |
| Alves, RV | 1 |
| Boddy, G | 1 |
| Hong, SJ | 3 |
| Liang, HC | 1 |
| Shen, CJ | 1 |
| Iizuka, T | 1 |
| Nagai, M | 1 |
| Unno, T | 2 |
| Matsuyama, H | 1 |
| Sakamoto, T | 1 |
| Uchiyama, M | 1 |
| Izumi, Y | 1 |
| Okamoto, H | 2 |
| Yamada, M | 1 |
| Wess, J | 1 |
| Komori, S | 2 |
| Saleh, S | 1 |
| Yeung, SY | 1 |
| Prestwich, S | 1 |
| Pucovsky, V | 1 |
| Greenwood, I | 1 |
| Obara, K | 1 |
| Uchino, M | 1 |
| Koide, M | 1 |
| Yamanaka, A | 1 |
| Nakayama, K | 6 |
| Hashitani, H | 2 |
| Suzuki, H | 4 |
| Daitoku, K | 1 |
| Seya, K | 1 |
| Furukawa, K | 1 |
| Motomura, S | 1 |
| Guo, HS | 1 |
| Yang, YZ | 1 |
| Zou, Y | 1 |
| Xu, J | 1 |
| Cai, ZX | 1 |
| Qi, QH | 1 |
| Clark, J | 1 |
| Milakovic, M | 1 |
| Cull, A | 1 |
| Klose, MK | 1 |
| Mercier, AJ | 1 |
| Kou, K | 1 |
| Siegel, H | 1 |
| Jim, K | 1 |
| Bolger, GT | 1 |
| Gengo, P | 1 |
| Triggle, DJ | 1 |
| Nishikori, K | 1 |
| Takenaka, T | 2 |
| Maeno, H | 2 |
| Fujiwara, S | 2 |
| Kuriyama, H | 1 |
| Ohizumi, Y | 1 |
| Kajiwara, A | 1 |
| Yasumoto, T | 1 |
| Advenier, C | 7 |
| Cerrina, J | 2 |
| Duroux, P | 2 |
| Floch, A | 2 |
| Pradel, J | 1 |
| Renier, A | 3 |
| Lefer, AM | 1 |
| Leprán, I | 1 |
| Roth, DM | 1 |
| Smith, JB | 1 |
| Jones, RI | 1 |
| Hornung, RS | 1 |
| Sonecha, T | 1 |
| Raftery, EB | 1 |
| Takata, Y | 5 |
| Kato, H | 7 |
| Ishii, K | 4 |
| Terai, M | 1 |
| Low, AM | 1 |
| Loke, JC | 1 |
| Kwan, CY | 1 |
| Suzuki, S | 1 |
| Uegomori, T | 1 |
| Ozaki, S | 1 |
| Chiba, Y | 1 |
| Misawa, M | 1 |
| Debdi, M | 1 |
| Seylaz, J | 1 |
| Sercombe, R | 1 |
| Cousins, HM | 2 |
| Edwards, FR | 2 |
| Hirst, GD | 2 |
| Macdonald, RL | 1 |
| Han, H | 1 |
| Yoshida, K | 1 |
| Iwase, J | 1 |
| Murakami, F | 1 |
| Usui, A | 1 |
| Hibi, M | 1 |
| Kawamura, M | 1 |
| Sato, K | 3 |
| Sanders, KM | 2 |
| Gerthoffer, WT | 1 |
| Publicover, NG | 2 |
| Tanaka, Y | 3 |
| Hata, S | 2 |
| Ishiro, H | 2 |
| Day, TA | 1 |
| Bennett, JL | 2 |
| Pax, RA | 2 |
| Saïag, B | 1 |
| Milon, D | 1 |
| Bentue-Ferrer, D | 1 |
| Allain, H | 1 |
| Rault, B | 1 |
| Van den Driessche, J | 1 |
| Spina, D | 1 |
| Goldie, RG | 2 |
| Naline, E | 5 |
| Candenas, ML | 2 |
| Palette, C | 1 |
| Moreau, J | 1 |
| Norte, M | 1 |
| Martin, JD | 1 |
| Pays, M | 1 |
| Toyooka, H | 3 |
| Amaha, K | 1 |
| Prostran, M | 1 |
| Todorović, Z | 1 |
| Varagić, VM | 1 |
| Kamata, K | 3 |
| Arai, Y | 1 |
| Kasuya, Y | 6 |
| Wendt, IR | 1 |
| Blair, KL | 1 |
| Bobo, MH | 1 |
| Magous, R | 2 |
| Christen, MO | 2 |
| Bali, JP | 2 |
| Le, SQ | 1 |
| Wasserstrum, N | 1 |
| Mombouli, JV | 1 |
| Vanhoutte, PM | 1 |
| Abe, A | 1 |
| Karaki, H | 4 |
| Matsui, T | 2 |
| Kaizu, H | 1 |
| Itoh, S | 1 |
| Asano, T | 3 |
| Bodelsson, G | 1 |
| Stjernquist, M | 1 |
| Kase, N | 1 |
| Yamura, T | 1 |
| Ohnishi, H | 1 |
| Moir, M | 1 |
| Holbrook, RH | 1 |
| Shimizu, K | 1 |
| Kaneda, T | 1 |
| Chihara, H | 1 |
| Kaburagi, T | 1 |
| Nakajyo, S | 1 |
| Urakawa, N | 2 |
| Kanda, M | 2 |
| Shirahase, H | 1 |
| Wada, K | 2 |
| Nakamura, S | 1 |
| Matsui, H | 2 |
| Fukata, F | 1 |
| Watanabe, Y | 1 |
| Suzuki, A | 1 |
| Itoh, T | 2 |
| Safak, C | 3 |
| Ozkanli, F | 1 |
| Erol, K | 3 |
| Aktan, Y | 1 |
| Simsek, R | 2 |
| Altas, Y | 1 |
| Boydag, S | 1 |
| Watanabe, K | 1 |
| Yano, S | 1 |
| Horie, S | 1 |
| Yamamoto, LT | 1 |
| Sato, T | 1 |
| Zsigmond, EK | 1 |
| Rabito, SF | 1 |
| Kageyama, M | 1 |
| Fujita, H | 1 |
| Nakata, K | 1 |
| Shirasawa, E | 1 |
| Shiraishi, Y | 1 |
| Ohashi, M | 1 |
| Kanmura, Y | 1 |
| Yamaguchi, S | 1 |
| Yoshimura, N | 1 |
| Inoue, K | 2 |
| Kamisaki, T | 1 |
| Takahashi, K | 1 |
| Sato, M | 1 |
| Sugai, K | 1 |
| Yanagisawa, T | 1 |
| Motohashi, O | 1 |
| Suzuki, M | 1 |
| Yoshimoto, T | 1 |
| Takahashi, N | 1 |
| Aizawa, H | 1 |
| Inoue, H | 1 |
| Matsumoto, K | 1 |
| Nakano, H | 1 |
| Hirose, T | 1 |
| Nishima, S | 1 |
| Hara, N | 1 |
| Uchida, K | 1 |
| Yuzuki, R | 1 |
| Kamikawa, Y | 1 |
| Takemoto, M | 1 |
| Ito, Y | 1 |
| Takagi, K | 1 |
| Ogino, K | 1 |
| Tomita, T | 1 |
| Japelj, I | 1 |
| Budihna, MV | 1 |
| Stanovnik, L | 1 |
| Krisch, I | 1 |
| Nishijima, H | 1 |
| Uchida, R | 1 |
| Kameyama, K | 1 |
| Kawakami, N | 1 |
| Ohkubo, T | 1 |
| Kitamura, K | 1 |
| Pape, D | 1 |
| Goineau, S | 1 |
| Guillo, P | 1 |
| Durand-Castel, X | 1 |
| Bellissant, E | 1 |
| Hay, DW | 2 |
| Luttmann, MA | 1 |
| Muccitelli, RM | 1 |
| Kageyama, S | 1 |
| Fujita, K | 1 |
| Suzuki, K | 1 |
| Shinbo, H | 1 |
| Masuda, N | 1 |
| Uchida, W | 1 |
| Shimamura, K | 1 |
| Sekiguchi, F | 1 |
| Sunano, S | 1 |
| Inaba, T | 1 |
| Ohashi, H | 1 |
| Takewaki, T | 1 |
| Boyer, JC | 1 |
| Balmes, JL | 1 |
| Sirmagül, B | 1 |
| Takeuchi, T | 1 |
| Sumiyoshi, M | 1 |
| Kitayama, M | 1 |
| Hirayama, N | 1 |
| Fujita, A | 1 |
| Hata, F | 1 |
| Rattan, S | 1 |
| Fan, YP | 1 |
| Puri, RN | 1 |
| Toda, N | 1 |
| Baba, H | 1 |
| Tanobe, Y | 1 |
| Okamura, T | 1 |
| Vila, JM | 3 |
| Martín de Aguilera, E | 2 |
| Irurzun, A | 3 |
| Aldasoro, M | 2 |
| Flor, B | 1 |
| Lluch, S | 3 |
| Sarria, B | 2 |
| Ebata, T | 1 |
| Sakata, K | 1 |
| Takano-Ohmuro, H | 1 |
| Tsuchiya, T | 1 |
| Sugi, H | 1 |
| Kato, I | 1 |
| Okamiya, Y | 1 |
| Kishimoto, T | 1 |
| Sunakawa, K | 1 |
| Aoki, K | 1 |
| Tanabe, H | 1 |
| Takeshita, T | 1 |
| Naruchi, T | 1 |
| Somasundaram, B | 1 |
| Tregear, RT | 1 |
| Trentham, DR | 1 |
| Nagata, K | 1 |
| Saito, H | 1 |
| Matsuki, N | 3 |
| Puybasset, L | 1 |
| Lagente, V | 1 |
| Rae, GA | 1 |
| Stevens, RJ | 1 |
| Blondfield, DP | 1 |
| Moummi, C | 1 |
| Gullikson, GW | 1 |
| Gaginella, TS | 1 |
| Dong, H | 1 |
| Lu, YQ | 1 |
| Yang, QQ | 1 |
| Wang, Q | 1 |
| Yang, ZC | 1 |
| Sugawa, M | 1 |
| Johshita, H | 2 |
| Takuwa, Y | 2 |
| Martinez, MC | 1 |
| Rodriguez, MD | 1 |
| Nishiyama, H | 1 |
| Miyata, N | 1 |
| Salom, JB | 1 |
| Torregrosa, G | 1 |
| Miranda, FJ | 1 |
| Alabadí, JA | 1 |
| Alvarez, C | 1 |
| Alborch, E | 1 |
| Nishimura, K | 1 |
| Miyawaki, N | 1 |
| Yamauchi, H | 1 |
| Chang, CC | 2 |
| Huang, CY | 2 |
| Kim, S | 1 |
| Morimoto, S | 1 |
| Koh, E | 1 |
| Morita, R | 1 |
| Kitano, S | 1 |
| Miyashita, Y | 1 |
| Fukuo, K | 1 |
| Imanaka, S | 1 |
| Ogihara, T | 1 |
| de Aguilera, EM | 1 |
| Galeote, MS | 1 |
| Tsuchiya, Y | 1 |
| Hosokawa, T | 1 |
| Adam, LP | 1 |
| Henderson, EG | 1 |
| Suzuki, T | 1 |
| Hoshi, H | 1 |
| Mitsui, Y | 1 |
| Kawata, H | 1 |
| Hatae, J | 2 |
| Edwards, R | 1 |
| Trizna, W | 1 |
| Sada, T | 1 |
| Koike, H | 1 |
| Ikeda, M | 1 |
| Matsuo, K | 2 |
| Uchida, S | 1 |
| Nakazawa, K | 1 |
| Shigenobu, K | 1 |
| Uchida, MK | 1 |
| Matran, R | 1 |
| Lockhart, A | 1 |
| Tricot, JF | 1 |
| Regoli, D | 1 |
| Turner, NC | 2 |
| Dollery, CT | 2 |
| Williams, AJ | 1 |
| D'Orleans-Juste, P | 2 |
| Finet, M | 1 |
| de Nucci, G | 2 |
| Vane, JR | 2 |
| Power, RF | 1 |
| Polak, JM | 1 |
| Bloom, SR | 1 |
| Chiou, LC | 1 |
| Hwang, LL | 1 |
| Goto, K | 2 |
| Kurihara, H | 1 |
| Ishikawa, T | 1 |
| Kimura, S | 2 |
| Yanagisawa, M | 2 |
| Masaki, T | 2 |
| Ninomiya, M | 1 |
| Tani, T | 1 |
| Nakajima, S | 1 |
| Ueda, M | 1 |
| Saito, A | 1 |
| Shiba, R | 1 |
| Nagase, H | 1 |
| Azuma, H | 1 |
| Nakajima, T | 1 |
| Kihara, H | 1 |
| Anraku, M | 1 |
| Ohno, M | 1 |
| Hashimura, S | 1 |
| Velena, AH | 1 |
| Dubur, GJ | 1 |
| Vitolina, RO | 1 |
| Kimenis, AA | 1 |
| Selga, MJ | 1 |
| Zarinsh, GV | 1 |
| Narusevicius, EV | 1 |
| Macianskiene, RA | 1 |
| Gendvilienè, VI | 1 |
| Simkhovich, BZ | 1 |
| Jayakody, RL | 2 |
| Senaratne, MP | 2 |
| Kappagoda, T | 1 |
| Osumi, S | 1 |
| Morishita, S | 1 |
| Usui, H | 1 |
| Kakeya, N | 1 |
| Salvador, A | 1 |
| del Pozo, E | 1 |
| Carlos, R | 1 |
| Baeyens, JM | 1 |
| Nakagomi, T | 1 |
| Kassell, NF | 1 |
| Sasaki, T | 1 |
| Lehman, RM | 1 |
| Torner, JC | 1 |
| Tsuchida, K | 1 |
| Yamazaki, R | 1 |
| Kaneko, K | 1 |
| Aihara, H | 1 |
| Sato, Y | 1 |
| Fujino, M | 1 |
| Kappagoda, CT | 1 |
| Hidaka, H | 1 |
| Kurihara, J | 1 |
| Miyajima, Y | 1 |
| Oomiya, A | 1 |
| Kokumi, N | 1 |
| Hagiwara, Y | 1 |
| Hara, T | 1 |
| Hirashima, T | 1 |
1 review available for nicardipine and Muscle Contraction
| Article | Year |
|---|---|
Cardiovascular pharmacology: an update.
Topics: Animals; Cardiovascular Agents; Cardiovascular Diseases; Diastole; Heart Failure; Humans; Hydrazones | 2010 |
153 other studies available for nicardipine and Muscle Contraction
| Article | Year |
|---|---|
New 1,4-dihydropyridine derivatives combining calcium antagonism and alpha-adrenolytic properties.
Topics: Animals; Aorta; Calcium Channel Blockers; Calcium Chloride; Cerebral Cortex; Chemical Phenomena; Che | 1989 |
Novel calcium antagonists. Synthesis and structure-activity relationship studies of benzothiazoline derivatives.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Guinea Pigs; Heart | 1988 |
Arecoline hydrobromide enhances jejunum smooth muscle contractility via voltage-dependent potassium channels in W/Wv mice.
Topics: Animals; Arecoline; Atropine; Dose-Response Relationship, Drug; Gastrointestinal Motility; Jejunum; | 2021 |
An organotypic slice model for ex vivo study of neural, immune, and microbial interactions of mouse intestine.
Topics: Animals; Anti-Bacterial Agents; Calcium Channel Blockers; Cell Proliferation; Enterocytes; Female; I | 2016 |
The role of caveolae and caveolin 1 in calcium handling in pacing and contraction of mouse intestine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2009 |
Time-dependent phenotypic and contractile changes of pulmonary artery in chronic hypoxia-induced pulmonary hypertension.
Topics: Actins; Amides; Animals; Cell Proliferation; Endothelin-1; Hypertension, Pulmonary; Hypoxia; Immunoh | 2009 |
[Effects of modulators of calcium metabolism on mesenteric artery contractions during activation of P2X receptors in guinea-pig].
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Endopl | 2009 |
The first intestinal motility patterns in fetal mice are not mediated by neurons or interstitial cells of Cajal.
Topics: Animals; Calcium Channels, L-Type; Cobalt; Colon; Duodenum; Female; Fetus; Gastrointestinal Motility | 2010 |
Contractile signaling pathways in mouse prostate smooth muscle.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Atropine; Calcium; Calcium Channel Blockers; Chol | 2013 |
Patterns of intracellular and intercellular Ca2+ waves in the longitudinal muscle layer of the murine large intestine in vitro.
Topics: Anesthetics, Local; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; | 2002 |
Involvement of T-type calcium channels in excitatory junction potentials in rat resistance mesenteric arteries.
Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Electric Stimul | 2002 |
The vasodilatory effects of hydralazine, nicardipine, nitroglycerin, and fenoldopam in the human umbilical artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Dopamine; Dose-Response Relation | 2003 |
Effects of three different L-type Ca2+ entry blockers on airway constriction induced by muscarinic receptor stimulation.
Topics: Animals; Bronchoconstriction; Calcium Channel Blockers; Calcium Channels, L-Type; Diltiazem; Dogs; D | 2003 |
Effects of diltiazem compared with nicardipine on diaphragmatic fatigability in vivo.
Topics: Animals; Calcium Channel Blockers; Diaphragm; Diltiazem; Dogs; Electric Stimulation; Female; Male; M | 2003 |
Circumferential, not longitudinal, colonic stretch increases synaptic input to mouse prevertebral ganglion neurons.
Topics: Afferent Pathways; Animals; Colon; Excitatory Postsynaptic Potentials; Ganglia, Sympathetic; Male; M | 2003 |
New evidence on the mechanisms underlying bradykinin-mediated contraction of the pig iris sphincter in vitro.
Topics: Animals; Benzamides; Bradykinin; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Re | 2003 |
Inhibitory effects of potassium channel blockers on carbachol-induced contraction in rat detrusor muscle.
Topics: 4-Aminopyridine; Animals; Calcium; Calcium Channel Blockers; Carbachol; Dose-Response Relationship, | 2003 |
The role of calcium channels in substance P-induced contractile response in the rat iris.
Topics: Amiloride; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Econazole; In Vitro Techniq | 2003 |
Role of l-Ca(2+) channels in intestinal pacing in wild-type and W/W(V) mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2005 |
Alteration of cyclopiazonic acid-mediated contracture of mouse diaphragm after denervation.
Topics: Action Potentials; Animals; Biological Assay; Boron Compounds; Caffeine; Cromakalim; Crotalid Venoms | 2005 |
[Vasorelaxant effects of forsythiaside from the fruits of Forsythia suspensa].
Topics: Animals; Aorta; Calcium; Calcium Channels; Dose-Response Relationship, Drug; Extracellular Space; Fo | 2005 |
M(2) and M(3) muscarinic receptor-mediated contractions in longitudinal smooth muscle of the ileum studied with receptor knockout mice.
Topics: Animals; Calcium Channel Blockers; Carbachol; Cholinergic Agonists; Diamines; Female; Ileum; In Vitr | 2005 |
Electrophysiological and molecular identification of voltage-gated sodium channels in murine vascular myocytes.
Topics: Action Potentials; Animals; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Fem | 2005 |
Stretch-induced triphosphorylation of myosin light chain and myogenic tone in canine basilar artery.
Topics: Amides; Animals; Azepines; Basilar Artery; Calcium; Calcium Channel Blockers; Dogs; In Vitro Techniq | 2006 |
Properties of spontaneous Ca2+ transients recorded from interstitial cells of Cajal-like cells of the rabbit urethra in situ.
Topics: Adrenergic alpha-Agonists; Animals; Boron Compounds; Caffeine; Calcium Channel Blockers; Calcium Cha | 2007 |
Assessment of the effects of L- and N-type Ca2+ channel blocking drugs using canine blood-perfused papillary muscle preparations.
Topics: Adrenergic alpha-Agonists; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Chan | 2007 |
Effects of dendroaspis natriuretic peptide on calcium-activated potassium current and its mechanism.
Topics: Aminoquinolines; Animals; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug | 2008 |
Evidence for postsynaptic modulation of muscle contraction by a Drosophila neuropeptide.
Topics: Amiloride; Amino Acid Sequence; Animals; Calcium Channels, L-Type; Calcium Channels, T-Type; Dose-Re | 2008 |
Electrical components contributing to the nerve-mediated contractions in the smooth muscles of the rabbit ear artery.
Topics: Action Potentials; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Female; Guanethi | 1983 |
Specific and non-specific desensitization of guinea-pig ileal smooth muscle.
Topics: Animals; Calcium; Calcium Channel Blockers; Dioxolanes; Guinea Pigs; Histamine; Ileum; In Vitro Tech | 1984 |
A possible mechanism for relaxation of rat uterine smooth muscle by nicardipine hydrochloride (YC-93), a new potent vasodilator.
Topics: Adenosine Triphosphatases; Adenylyl Cyclases; Animals; Female; In Vitro Techniques; Microsomes; Musc | 1981 |
Nicardipine actions on smooth muscle cells and neuromuscular transmission in the guinea-pig basilar artery.
Topics: Adenosine Triphosphate; Animals; Basilar Artery; Calcium; Electric Stimulation; Female; Guinea Pigs; | 1983 |
Excitatory effect of the most potent marine toxin, maitotoxin, on the guinea-pig vas deferens.
Topics: Animals; Calcium; Calcium Channel Blockers; Cell Membrane; Chlorpheniramine; Dose-Response Relations | 1983 |
Sodium cromoglycate, verapamil and nicardipine antagonism to leukotriene D4 bronchoconstriction.
Topics: Airway Resistance; Animals; Bronchi; Cromolyn Sodium; Guinea Pigs; Lung Compliance; Male; Muscle Con | 1983 |
Specificity of anti-leukotriene actions of nicardipine.
Topics: Animals; Cats; Coronary Vessels; Guinea Pigs; In Vitro Techniques; Lung; Male; Muscle Contraction; M | 1984 |
Effects of five different organic calcium antagonists on guinea-pig isolated trachea.
Topics: Animals; Anti-Arrhythmia Agents; Bepridil; Calcium Channel Blockers; Diltiazem; Dose-Response Relati | 1984 |
The effect of a new calcium channel blocker nicardipine on 24-hour ambulatory blood pressure and the pressor response to isometric and dynamic exercise.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Female; Heart Rate; Humans; Hypertension; Iso | 1983 |
Effects of Ca antagonists on the norepinephrine release and contractile responses of isolated canine saphenous veins to transmural nerve stimulation.
Topics: Adrenergic Fibers; Animals; Calcium; Calcium Channel Blockers; Diltiazem; Dogs; Electric Stimulation | 1984 |
Effect of Ca-antagonists on the contraction of cerebral and peripheral arteries produced by electrical and mechanical stimuli.
Topics: Animals; Arteries; Calcium Channel Blockers; Cerebral Arteries; Dogs; Electric Stimulation; Humans; | 1983 |
Inhibition of calcium influx in rabbit aorta by nicardipine hydrochloride (YC-93).
Topics: Animals; Aorta, Thoracic; Biological Transport; Calcium; In Vitro Techniques; Lanthanum; Muscle Cont | 1981 |
Sensitivity to protein kinase C inhibitors of nicardipine-insensitive component of high K+ contracture in rat and guinea-pig aorta.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aorta, Thoracic; Calcium; Guinea Pigs; Hyper | 1994 |
Effects of benidipine hydrochloride on contractions induced by some contractile agents in isolated cerebral and mesenteric arteries of dogs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcium Channel Blocker | 1995 |
Alteration in Ca2+ availability involved in antigen-induced airway hyperresponsiveness in rats.
Topics: Acetylcholine; Animals; Antigens, Helminth; Ascaris suum; Bronchial Hyperreactivity; Bronchoconstric | 1995 |
Increased influence of calcium and nicardipine on rabbit basilar artery reactivity after brief subarachnoid hemorrhage.
Topics: Animals; Basilar Artery; Calcium; Extracellular Space; In Vitro Techniques; Isometric Contraction; M | 1993 |
Neuronally released and applied acetylcholine on the longitudinal muscle of the guinea-pig ileum.
Topics: Acetylcholine; Animals; Barium; Female; Guinea Pigs; Ileum; Male; Membrane Potentials; Muscle Contra | 1995 |
Angioplasty reduces pharmacologically mediated vasoconstriction in rabbit carotid arteries with and without vasospasm.
Topics: Acetylcholine; Analysis of Variance; Angioplasty; Animals; Carotid Arteries; In Vitro Techniques; Is | 1995 |
The effects of calcium antagonists and prostaglandin E1 on isolated canine coronary arterial tension.
Topics: Alprostadil; Animals; Calcium; Calcium Channel Blockers; Coronary Vessels; Data Interpretation, Stat | 1994 |
Sources of calcium utilized in cholinergic responses in canine colonic smooth muscle.
Topics: Acetylcholine; Animals; Caffeine; Calcium; Colon; Dogs; Female; Male; Muscle Contraction; Muscle, Sm | 1994 |
Quick stretch increases the production of inositol 1,4,5-trisphosphate (IP3) in porcine coronary artery.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Animals; Atropine; Carbamates; Coronary Vessels; Female; | 1994 |
Serotonin and its requirement for maintenance of contractility in muscle fibres isolated from Schistosoma mansoni.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Antimony Potassium Tartrate; Calcium; Cobalt; Colfo | 1994 |
Inhibitor effects of diltiazem, nicardipine, nifedipine and verapamil on the norepinephrine-induced contractions of the canine saphenous vein in calcium-free medium.
Topics: Animals; Calcium; Calcium Channel Blockers; Culture Media; Diltiazem; Dogs; Electrophysiology; Muscl | 1994 |
Contractile properties of synthetic cationic polypeptides in guinea-pig isolated trachea.
Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; Glycopeptides; Guinea Pigs; Heparin; I | 1994 |
Stretching releases Ca2+ from intracellular storage sites in canine cerebral arteries.
Topics: Animals; Basilar Artery; Caffeine; Calcium; Calcium Channel Blockers; Carbamates; Cholera Toxin; Dog | 1994 |
Effects of okadaic acid on the human isolated bronchus.
Topics: Acetylcholine; Bronchi; Cadmium; Cadmium Compounds; Caffeine; Dose-Response Relationship, Drug; Ethe | 1994 |
Nicardipine enhances diaphragmatic fatigue.
Topics: Animals; Atrial Function, Right; Blood Pressure; Cardiac Output; Diaphragm; Dogs; Electromyography; | 1994 |
Some new evidence on antifatigue action of aminophylline on the isolated hemidiaphragm of the rat.
Topics: Adrenergic beta-Antagonists; Aminophylline; Animals; Calcium; Diaphragm; Electric Stimulation; Femal | 1993 |
Mechanism of the contractile response to platelet-activating factor (PAF) of the rat stomach fundus. I. PAF-induced contractile response and calcium mobilization.
Topics: Animals; Calcium; Gastric Fundus; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nic | 1993 |
Cholinergic neuromuscular transmission in the longitudinal muscle of the guinea-pig ileum.
Topics: Action Potentials; Animals; Calcium; Cholinergic Fibers; Diltiazem; Electric Stimulation; Electrophy | 1993 |
Schistosoma mansoni: myogenic characteristics of phorbol ester-induced muscle contraction.
Topics: Acetylcholine; Animals; Cadmium; Calcimycin; Calcium; Calcium Channels; Carbachol; Cell Membrane Per | 1994 |
Effect of pinaverium and other calcium channel blockers on contraction of isolated gastric antral smooth muscle cells caused by gastrointestinal hormones.
Topics: Animals; Calcium; Calcium Channel Blockers; Diltiazem; Gastrins; Gastrointestinal Hormones; In Vitro | 1994 |
Role of extracellular calcium and calcium channels in the response of human placental venous smooth muscle to endothelin-1.
Topics: Adult; Calcium; Calcium Channels; Endothelins; Extracellular Space; Female; Humans; In Vitro Techniq | 1993 |
Synergistic effects of cyclic AMP-related vasodilators and the phosphatase inhibitor okadaic acid.
Topics: Animals; Aorta; Atrial Natriuretic Factor; Bucladesine; Colforsin; Drug Synergism; Ethers, Cyclic; M | 1993 |
The role of active smooth-muscle contraction in the occurrence of chronic vasospasm in the canine two-hemorrhage model.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Basilar Artery; Dogs; Female; Ischemic Attac | 1994 |
Characterization of endothelin receptors and localization of 125I-endothelin-1 binding sites in human umbilical artery.
Topics: Arginine; Binding Sites; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothel | 1993 |
[Pharmacological profile of F-0401, a novel dihydropyridine derivative. (2). The vasodilator action of F-0401 in isolated canine arteries].
Topics: Animals; Arteries; Calcium Channels; Dihydropyridines; Dogs; Female; In Vitro Techniques; Male; Musc | 1993 |
Effect of nicardipine on the reversal of magnesium toxicity by calcium gluconate in nonpregnant rabbits.
Topics: Animals; Calcium Gluconate; Depression, Chemical; Electric Stimulation; Female; Magnesium; Muscle Co | 1993 |
Electrical and mechanical responses produced by nerve stimulation in detrusor smooth muscle of the guinea-pig.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Atropine; Calcium Channel Blockers; Electric Stimula | 1995 |
Effects of phenylephrine on the contractile tension and cytosolic Ca2+ level in rat anococcygeus muscle.
Topics: Adrenergic alpha-Agonists; Animals; Calcium; Calcium Channel Blockers; Cytosol; In Vitro Techniques; | 1995 |
Effects of the novel water-soluble calcium antagonist (+/-)-3-(4-allyl-1-piperazinyl)-2,2-dimethylpropyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate dihydrochloride on the endothelium-independent and endothelium-dependent c
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Calcium Channel Blockers; Cerebral Arteries; Dihydrop | 1996 |
Effect of membrane hyperpolarization induced by a K+ channel opener on histamine-induced Ca2+ mobilization in rabbit arterial smooth muscle.
Topics: Animals; Benzopyrans; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Histamine | 1996 |
3-Acetyl-4-aryl-5-oxo-2,7,7-trimethyl-1,4,5,6,7,8-hexahydro-quinoline derivatives and their calcium antagonistic activities.
Topics: Animals; Calcium Channel Blockers; Female; Guinea Pigs; In Vitro Techniques; Magnetic Resonance Spec | 1995 |
One pot synthesis of some new substituted hexahydro 2H-1,3-benzoxazine derivatives.
Topics: Animals; Calcium Channel Blockers; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Sm | 1996 |
Inhibitory effect of mitragynine, an alkaloid with analgesic effect from Thai medicinal plant Mitragyna speciosa, on electrically stimulated contraction of isolated guinea-pig ileum through the opioid receptor.
Topics: Acetylcholine; Analgesics; Animals; Clonidine; Diterpene Alkaloids; Electric Stimulation; Guinea Pig | 1997 |
Ketamine relaxes airway smooth muscle contracted by endothelin.
Topics: Anesthetics, Dissociative; Animals; Calcium; Calcium Channels; Carbachol; Egtazic Acid; Endothelin-1 | 1997 |
Involvement of both L- and N-type voltage-dependent Ca2+ channels in KCl- and veratridine-evoked transmitter release from non-adrenergic, non-cholinergic nerves in the rabbit iris sphincter muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1997 |
Possible mechanisms underlying the midazolam-induced relaxation of the noradrenaline-contraction in rabbit mesenteric resistance artery.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; In Vitro Techniques; Male; Membrane Potentials | 1997 |
Regional differences in calcium sensitivity in the guinea-pig intestine.
Topics: Adrenergic alpha-Agonists; Animals; Atropine; Calcium; Calcium Channel Blockers; Guinea Pigs; In Vit | 1997 |
Measurement of intracellular Ca2+ concentration changes by use of fura-2 in the generation of myogenic contraction of dog cerebral artery in response to quick stretch.
Topics: Animals; Calcium; Calcium Channel Blockers; Cerebral Arteries; Diltiazem; Dogs; Female; Fluorescent | 1998 |
Levcromakalim decreases vascular tone, cytoplasmic Ca2+ and Ca2+ sensitivity in canine basilar artery.
Topics: Animals; Basilar Artery; Calcium; Calcium Channel Blockers; Cromakalim; Cytoplasm; Dogs; Dose-Respon | 1998 |
Effects of epinastine hydrochloride on cholinergic neuro-effector transmission in canine tracheal smooth muscle.
Topics: Animals; Calcium Channel Blockers; Cholinergic Agents; Cholinergic Fibers; Dibenzazepines; Dogs; Ele | 1998 |
Ba2+ selectively inhibits receptor-mediated contraction of the esophageal muscularis mucosae.
Topics: Acetylcholine; Animals; Barium; Barium Compounds; Calcium Channels; Chlorides; Cholinergic Antagonis | 1998 |
Effects of excess K+ on carbachol-induced contractions in the guinea-pig tracheal muscle.
Topics: Animals; Calcium; Calcium Channel Blockers; Carbachol; Drug Combinations; Guinea Pigs; Muscle Contra | 1998 |
Stereoselective and endothelium-independent action of nicardipine on the isolated porcine coronary artery.
Topics: Animals; Calcium Channel Blockers; Coronary Vessels; Dose-Response Relationship, Drug; Endothelium, | 1999 |
Mechanisms mediating the vasorelaxing action of eugenol, a pungent oil, on rabbit arterial tissue.
Topics: Animals; Aorta, Thoracic; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Dose-Response Relation | 1999 |
Endothelin, but not angiotensin II, contributes to the hypoxic contractile response of large isolated pulmonary arteries in the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhib | 1999 |
Endothelin receptors and calcium translocation pathways in human airways.
Topics: Bronchi; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Endothelin Receptor An | 1999 |
Effect of age on the responses of rat bladder detrusor strips to adenosine triphosphate.
Topics: Acetylcholine; Adenosine Triphosphate; Aging; Animals; Dose-Response Relationship, Drug; Egtazic Aci | 2000 |
Altered beta-adrenoceptor-mediated responses in the gastric smooth muscle of hypertensive rats.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Calcium Channel Blockers; Colforsin; Electrophysiology; | 2000 |
Different effects of olprinone on contractility in nonfatigued and fatigued diaphragm in dogs.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Calcium Channel Blockers; Cyclic Nucleotide Phosphodie | 2000 |
Role of Ca2+ mobilization in muscarinic receptor-mediated membrane depolarization in guinea pig ileal smooth muscle cells.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Carbachol; Cholinergic Agonists; Enzym | 2000 |
Contraction of human colonic circular smooth muscle cells is inhibited by the calcium channel blocker pinaverium bromide.
Topics: Adult; Aged; Aged, 80 and over; Binding Sites; Calcium Channel Blockers; Calcium Channels, L-Type; C | 2001 |
Synthesis of hexahydroquinoline derivatives possessing calcium antagonistic activity.
Topics: Animals; Calcium Channel Blockers; Female; In Vitro Techniques; Magnetic Resonance Spectroscopy; Mal | 2001 |
Origin of Ca2+ necessary for carbachol-induced contraction in longitudinal muscle of the proximal colon of rats.
Topics: Aminobenzoates; Animals; Caffeine; Calcium; Calcium Channel Blockers; Carbachol; Chlorobenzoates; Ci | 2001 |
Comparison of angiotensin II (Ang II) effects in the internal anal sphincter (IAS) and lower esophageal sphincter smooth muscles.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Anal Canal; Angiotensin II; Animals; Dose-Response Re | 2002 |
Mechanism of relaxation induced by K+ and nicotine in dog duodenal longitudinal muscle.
Topics: Adenosine Triphosphate; Animals; Apamin; Atropine; Bradykinin; Cations, Monovalent; Cyclic GMP; Dogs | 1992 |
Changes in muscarinic responsiveness, muscarinic receptor density and Ca2+ mobilization of the urinary bladder in streptozotocin-induced diabetic rats.
Topics: Acetylcholine; Animals; Blood Glucose; Body Weight; Calcium; Calcium Channels; Diabetes Mellitus, Ex | 1992 |
Contractile response of human omental arteries to endothelin.
Topics: Adult; Aged; Arteries; Calcium; Calcium Channels; Electric Stimulation; Endothelins; Endothelium, Va | 1992 |
Effect of epithelium removal and of enkephalin inhibition on the bronchoconstrictor response to three endothelins of the human isolated bronchus.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1992 |
Dobutamine increases diaphragmatic contractility in dogs.
Topics: Alprostadil; Anesthesia, Intravenous; Animals; Blood Pressure; Cardiac Output; Diaphragm; Dobutamine | 1992 |
Receptor agonists induce myosin phosphorylation-dependent and phosphorylation-independent contractions in vascular smooth muscle.
Topics: Animals; Calcium; Dinoprost; Drug Interactions; Male; Muscle Contraction; Muscle, Smooth, Vascular; | 1992 |
Antihypertensive effect of the new dihydropyridine calcium antagonist (+-)-3-(benzylmethylamino)-2,2-dimethylpropyl methyl 4-(2-fluoro-5-nitrophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedica rbo xylate hydrochloride in dogs.
Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyrid | 1992 |
GTP gamma S causes contraction of skinned frog skeletal muscle via the DHP-sensitive Ca2+ channels of sealed T-tubules.
Topics: Animals; Binding Sites; Binding, Competitive; Caffeine; Calcium Channels; Dihydropyridines; Egtazic | 1991 |
Efficient Ca2+ mobilization induced by neurokinin A in rat vas deferens.
Topics: Animals; Calcium; Calcium Chloride; Epididymis; In Vitro Techniques; Kinetics; Male; Muscle Contract | 1991 |
Contractile activity of three endothelins (ET-1, ET-2 and ET-3) on the human isolated bronchus.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
Mechanism of endothelin-induced contraction in guinea-pig trachea: comparison with rat aorta.
Topics: Animals; Aorta, Thoracic; Calcium; Carbachol; Endothelins; Guinea Pigs; In Vitro Techniques; Male; M | 1990 |
Effects of endothelins on nerve-mediated contractions of the mouse vas deferens.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
Simultaneous measurement of membrane potential, cytosolic Ca2+, and tension in intact smooth muscles.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1991 |
Effect of endothelin-1 on guinea pig gallbladder smooth muscle in vitro.
Topics: Animals; Arachidonic Acid; Atropine; Calcium; Cations, Divalent; Diltiazem; Endothelins; Gallbladder | 1992 |
Antagonistic effects of dihydropyridines and verapamil on CaCl2 and 5-HT-evoked contraction in porcine coronary artery.
Topics: Animals; Calcium Chloride; Coronary Vessels; Dihydropyridines; Felodipine; In Vitro Techniques; Musc | 1991 |
Activation of the protein kinase C-mediated contractile system in canine basilar artery undergoing chronic vasospasm.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Basilar Artery; Chronic Disease; Dinoprost; | 1991 |
Endothelin action on goat cerebral arteries.
Topics: Animals; Calcium; Cerebral Arteries; Endothelins; Endothelium, Vascular; Female; Goats; In Vitro Tec | 1990 |
Changes in responsiveness of the canine basilar artery to endothelin-1 after subarachnoid hemorrhage.
Topics: Animals; Basilar Artery; Calcium; Calcium Channel Blockers; Dihydropyridines; Dogs; Endothelins; In | 1991 |
Effects of Ca2+ entry blockers on CaCl2-, KCl- and noradrenaline-induced contractions of goat cerebral arteries.
Topics: Animals; Calcium Channel Blockers; Calcium Chloride; Cerebral Arteries; Egtazic Acid; Female; Goats; | 1990 |
Tissue selectivity of the novel calcium antagonist sesamodil fumarate in isolated smooth muscles and cardiac muscles.
Topics: Animals; Calcimycin; Calcium Channel Blockers; Diltiazem; Guinea Pigs; Heart; Male; Muscle Contracti | 1990 |
Organic calcium channel antagonists provoke acetylcholine receptor autodesensitization on train stimulation of motor nerve.
Topics: Animals; Bungarotoxins; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Diaph | 1990 |
Nicorandil is a potent dilator of endothelin-induced vascular contraction.
Topics: Animals; Aorta; Calcium; Dose-Response Relationship, Drug; Endothelins; Muscle Contraction; Muscle, | 1990 |
Role of endothelium and calcium channels in endothelin-induced contraction of human cerebral arteries.
Topics: Adult; Aged; Calcium Channels; Cerebral Arteries; Endothelins; Endothelium, Vascular; Female; Humans | 1990 |
Influence of ouabain on the cholinergic neurotransmission in the canine trachea.
Topics: Acetylcholine; Animals; Atropine; Dogs; Electric Stimulation; In Vitro Techniques; Male; Muscle Cont | 1990 |
Calcium channel effectors are potent non-competitive blockers of acetylcholine receptors.
Topics: Animals; Bepridil; Calcium Channel Agonists; Calcium Channels; Cell Membrane; Electric Conductivity; | 1990 |
Endothelin stimulates hypertrophy and contractility of neonatal rat cardiac myocytes in a serum-free medium.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Cells, Cultured; Endothelins; In Vi | 1990 |
Dependence of contractile responses by some calcium antagonists on external calcium in the skeletal muscle.
Topics: Animals; Caffeine; Calcium; Membrane Potentials; Muscle Contraction; Muscles; Nicardipine; Ranidae; | 1990 |
Response of isolated intracerebral arterioles to endothelins.
Topics: Animals; Arterioles; Cerebral Cortex; Endothelins; Muscle Contraction; Nicardipine; Rats; Rats, Inbr | 1990 |
Cytosolic free calcium of aorta in hypertensive rats. Chronic inhibition of angiotensin converting enzyme.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Calcium; Cytosol; Hypertension; Male; Musc | 1990 |
Effects of Ca antagonists on the norepinephrine release and contractile responses of isolated canine saphenous veins to high KCl.
Topics: 1-Methyl-3-isobutylxanthine; Anesthetics, Local; Animals; Calcium Channel Blockers; Diltiazem; Dogs; | 1985 |
[Synergism of the calcium reversal phenomenon of potassium depolarizing in the rat uterine muscle by Bay k-8644, a calcium agonist].
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1985 |
Effects of Bay K 8644 on contraction of the human isolated bronchus and guinea-pig isolated trachea.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1986 |
Contractile response and electrophysiological properties in enzymatically dispersed smooth muscle cells of rat vas deferens.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Cesium; In Vitro Techniques; Ion Channels; Male; | 1987 |
Opposite effects of Bay k 8644 and nicardipine on the inhibitory effect of Ca2+ on rat myometrium.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1987 |
Role of extracellular calcium in the effects of substance P and neurokinin A on guinea pig trachea and human bronchus.
Topics: Animals; Bronchi; Calcium; Guinea Pigs; Humans; In Vitro Techniques; Isoproterenol; Male; Muscle Con | 1988 |
Differential effects of verapamil, nicardipine and diltiazem on Ca2+-dependent and Ca2+-independent noradrenaline release and contraction in isolated canine saphenous veins.
Topics: Animals; Calcium; Diltiazem; Dogs; Female; In Vitro Techniques; Ion Channels; Male; Muscle Contracti | 1988 |
Endothelin-1-induced contractions of vascular and tracheal smooth muscle: effects of nicardipine and BRL 34915.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Cromakalim; Endothelins; Guinea Pigs; In Vitro Techniques; Mu | 1989 |
Pharmacology of endothelin-1 in isolated vessels: effect of nicardipine, methylene blue, hemoglobin, and gossypol.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1989 |
Endothelin-1 contracts isolated vessels independently of dihydropyridine-sensitive Ca2+ channel activation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1989 |
Endothelin-induced contractions of tracheal smooth muscle and identification of specific endothelin binding sites in the trachea of the rat.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1989 |
Nicardipine inhibits axon conduction but causes dual changes of acetylcholine release in the mouse motor nerve.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1989 |
Endothelin activates the dihydropyridine-sensitive, voltage-dependent Ca2+ channel in vascular smooth muscle.
Topics: Animals; Calcium; Calcium Channels; Coronary Vessels; Endothelins; In Vitro Techniques; Membrane Pot | 1989 |
Effects of S-312, a new calcium antagonist, on the mechanical and electrophysiological responses of isolated cardiovascular preparations.
Topics: Animals; Arteries; Calcium Channel Blockers; Cecum; Dihydropyridines; Electrophysiology; Guinea Pigs | 1989 |
Vasoconstrictor response of large cerebral arteries of cats to endothelin, an endothelium-derived vasoactive peptide.
Topics: Animals; Calcium; Cats; Cerebral Arteries; Endothelins; Female; In Vitro Techniques; Indomethacin; M | 1989 |
Contractile effects of jellyfish toxin extracted from Carybdea rastonii on isolated rabbit aorta.
Topics: Animals; Aorta, Thoracic; Chlorpromazine; Cnidarian Venoms; Drug Interactions; In Vitro Techniques; | 1986 |
Tetrodotoxin-unaffected depolarization of frog muscles induced by the venom of jellyfish (Genus aurelia).
Topics: Aminopyridines; Animals; Cnidarian Venoms; Hydrogen-Ion Concentration; In Vitro Techniques; Membrane | 1988 |
Effect of ryodipine on electromechanical parameters of heart and vessels, cAMP phosphodiesterase activity and swelling-contraction cycle of mitochondria.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Anura; Calcium Channel Blockers; Cardiovascular Agents | 1985 |
Differential effects of Ca antagonists on the noradrenaline release and contraction evoked by nerve stimulation in the presence of 4-aminopyridine.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium Channel Blockers; Diltiazem; Dogs; Electric Stimul | 1987 |
Effects of nicardipine and diltiazem on alpha-adrenoceptor responses in canine saphenous veins.
Topics: Animals; Azepines; Diltiazem; Dogs; Female; In Vitro Techniques; Male; Methoxamine; Muscle Contracti | 1987 |
Antihypertensive effect of NKY-722, a new water-soluble 1,4-dihydropyridine derivative, on conscious spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Dihydropyridines; Dogs; Dose-Response Relationship | 1988 |
Differential effects of calcium channel blocking agents on pancuronium- and suxamethonium-induced neuromuscular blockade.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Drug Synergism; Female; In Vitro Techniques; Muscle Co | 1988 |
Effect of hypoxia on the contractile response to KCl, prostaglandin F2 alpha, and hemoglobin.
Topics: Animals; Basilar Artery; Calcium; Dinoprost; Dogs; Endothelium, Vascular; Female; Hemoglobins; Hypox | 1987 |
Effects of the new calcium antagonist 2-nitratopropyl-3-nitratopropyl-2,6-dimethyl-4-(3-nitrophe nyl)- 1,4-dihydropyridine-3,5-dicarboxylate on cerebral circulation in dogs.
Topics: Animals; Basilar Artery; Calcium Channel Blockers; Cerebrovascular Circulation; Dihydropyridines; Di | 1987 |
Effects of nicardipine on frog skeletal muscle in normal and calcium-free media.
Topics: Action Potentials; Animals; Calcium; Calcium Channel Blockers; Muscle Contraction; Muscles; Nicardip | 1986 |
Inhibition of excitation-contraction coupling by a Ca channel blocker nicardipine at low temperature in frog twitch fibers.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Cold Temperature; Electrophysiology; Muscle Co | 1987 |
Effect of calcium antagonists on adrenergic mechanisms in canine saphenous veins.
Topics: Animals; Benzazepines; Calcium Channel Blockers; Diltiazem; Dogs; In Vitro Techniques; Muscle Contra | 1986 |
Intracellular Ca++ antagonist, HA1004: pharmacological properties different from those of nicardipine.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Coronary Circulation; Dogs; Heart Ventricles; | 1985 |
Calcium antagonistic properties of nicardipine, a dihydropyridine derivative assessed in isolated cerebral arteries and cardiac muscle.
Topics: Animals; Basilar Artery; Calcium Channel Blockers; Cardiac Glycosides; Cerebral Arteries; Cymarine; | 1985 |
[Effect of calcium antagonists on the portal vein].
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Carbon Tetrachloride Poisoning; Cats; Diltiazem; | 1985 |