Page last updated: 2024-11-01

nicardipine and Marfan Syndrome

nicardipine has been researched along with Marfan Syndrome in 2 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Marfan Syndrome: An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome (type 1) is associated with mutations in the gene encoding FIBRILLIN-1 (FBN1), a major element of extracellular microfibrils of connective tissue. Mutations in the gene encoding TYPE II TGF-BETA RECEPTOR (TGFBR2) are associated with Marfan syndrome type 2.

Research Excerpts

ExcerptRelevanceReference
"The antenatal diagnosis of aortic dissection carries a grave prognosis."1.39Successful management of aortic dissection in a patient with Marfan syndrome during pregnancy. ( Chang, CY; Chen, PH; Lam, CW; Yang, JM, 2013)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chang, CY1
Yang, JM1
Lam, CW1
Chen, PH1
Minato, N1
Itoh, T1
Natsuaki, M1
Furukawa, K1
Rikitake, K1
Yamamoto, H1

Other Studies

2 other studies available for nicardipine and Marfan Syndrome

ArticleYear
Successful management of aortic dissection in a patient with Marfan syndrome during pregnancy.
    American journal of obstetrics and gynecology, 2013, Volume: 208, Issue:2

    Topics: Adult; Aortic Aneurysm; Aortic Dissection; Blood Pressure; Calcium Channel Blockers; Coronary Angiog

2013
Perioperative coronary artery spasm in modified Bentall's operation for annulo-aortic ectasia in Marfan's syndrome. A case report of perioperative chordal rupture of the mitral valve.
    The Journal of cardiovascular surgery, 1995, Volume: 36, Issue:2

    Topics: Angina Pectoris, Variant; Aortic Aneurysm, Thoracic; Aortic Valve Insufficiency; Chordae Tendineae;

1995