nicardipine has been researched along with Liver Cirrhosis in 4 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study was designed to compare the pharmacokinetic handling of a single oral dose of nicardipine in normal subjects and in patients with hepatic cirrhosis and to compare the sensitivity of the two groups to its hypotensive effect." | 1.28 | The effect of hepatic cirrhosis on the pharmacokinetics and blood pressure response to nicardipine. ( Conway, EL; Drummer, OH; Louis, WJ; McNeil, JJ; Razak, TA; Sewell, RB; Smallwood, RA, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| García-Pagán, JC | 1 |
| Feu, F | 1 |
| Luca, A | 1 |
| Fernández, M | 1 |
| Pizcueta, P | 1 |
| Bosch, J | 1 |
| Rodés, J | 1 |
| Iwao, T | 2 |
| Toyonaga, A | 2 |
| Ikegami, M | 2 |
| Oho, K | 2 |
| Sumino, M | 2 |
| Sakaki, M | 2 |
| Shigemori, H | 1 |
| Nakayama, M | 1 |
| Sasaki, E | 1 |
| Tanikawa, K | 1 |
| Sugawara, H | 1 |
| Takagi, K | 1 |
| Ohkubo, K | 1 |
| Inoue, R | 1 |
| Razak, TA | 1 |
| McNeil, JJ | 1 |
| Sewell, RB | 1 |
| Drummer, OH | 1 |
| Smallwood, RA | 1 |
| Conway, EL | 1 |
| Louis, WJ | 1 |
2 trials available for nicardipine and Liver Cirrhosis
| Article | Year |
|---|---|
Nicardipine increases hepatic blood flow and the hepatic clearance of indocyanine green in patients with cirrhosis.
Topics: Aged; Female; Hemodynamics; Humans; Hypertension, Portal; Indocyanine Green; Liver Circulation; Live | 1994 |
Effects of vasopressin and nicardipine on hemodynamics and liver function in patients with cirrhosis: comparison with vasopressin alone.
Topics: Aged; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension, Portal; Liver; Liver Ci | 1993 |
2 other studies available for nicardipine and Liver Cirrhosis
| Article | Year |
|---|---|
Nicardipine infusion improved hepatic function but failed to reduce hepatic venous pressure gradient in patients with cirrhosis.
Topics: Adult; Aged; Female; Hemodynamics; Humans; Hypertension, Portal; Infusions, Intravenous; Liver; Live | 1992 |
The effect of hepatic cirrhosis on the pharmacokinetics and blood pressure response to nicardipine.
Topics: Adult; Aged; Antipyrine; Biotransformation; Blood Pressure; Female; Half-Life; Humans; Liver; Liver | 1990 |