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nicardipine and Left Ventricular Hypertrophy

nicardipine has been researched along with Left Ventricular Hypertrophy in 6 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Research Excerpts

ExcerptRelevanceReference
"The effects of long-term treatment with sustained-release nicardipine (nicardipine SR) on left ventricular hypertrophy and function were studied."7.69Effects of long-term treatment with sustained-release nicardipine on left ventricular hypertrophy and function in patients with essential hypertension. ( Hiwada, K; Imamura, Y; Joh, T; Matsubara, W; Ochi, T; Sumimoto, T, 1994)
"We investigated the potential role of increased plasma adrenomedullin and brain natriuretic peptide (BNP) levels in a patient with malignant hypertension."7.69Antihypertensive therapy reduces increased plasma levels of adrenomedullin and brain natriuretic peptide concomitant with regression of left ventricular hypertrophy in a patient with malignant hypertension. ( Ishikawa, K; Kangawa, K; Kawano, Y; Kitamura, K; Matsuo, H; Matsuoka, H; Nishikimi, T; Omae, T; Saito, Y; Yoshihara, F, 1996)
"The aim of this study was to compare the effects of a calcium antagonist, nicardipine SR, with an angiotensin-converting enzyme (ACE) inhibitor, alacepril, on the regression of left ventricular hypertrophy (LVH) and function."5.08Both a calcium antagonist and ACE inhibitor reverse hypertrophy in hypertension but a calcium antagonist also depresses contractility. ( Hiwada, K; Ito, T; Joh, T; Muneta, S; Ochi, T; Sumimoto, T, 1997)
" Although the role of antihypertensive therapy in regression of LVH remains controversial, the calcium antagonist nicardipine appears to have an important role to play in the treatment of LVH in hypertension and in congestive heart failure."4.78Therapeutic advances in the treatment of left ventricular hypertrophy. ( Natsume, T, 1993)
"The effects of long-term treatment with sustained-release nicardipine (nicardipine SR) on left ventricular hypertrophy and function were studied."3.69Effects of long-term treatment with sustained-release nicardipine on left ventricular hypertrophy and function in patients with essential hypertension. ( Hiwada, K; Imamura, Y; Joh, T; Matsubara, W; Ochi, T; Sumimoto, T, 1994)
"We investigated the potential role of increased plasma adrenomedullin and brain natriuretic peptide (BNP) levels in a patient with malignant hypertension."3.69Antihypertensive therapy reduces increased plasma levels of adrenomedullin and brain natriuretic peptide concomitant with regression of left ventricular hypertrophy in a patient with malignant hypertension. ( Ishikawa, K; Kangawa, K; Kawano, Y; Kitamura, K; Matsuo, H; Matsuoka, H; Nishikimi, T; Omae, T; Saito, Y; Yoshihara, F, 1996)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (66.67)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kosaka, T1
Nakagawa, M1
Ishida, M1
Iino, K1
Watanabe, H1
Hasegawa, H1
Ito, H1
Rakić, D1
Rumboldt, Z1
Bagatin, J1
Polić, S1
Sumimoto, T2
Hiwada, K2
Ochi, T2
Matsubara, W1
Joh, T2
Imamura, Y1
Natsume, T1
Ito, T1
Muneta, S1
Nishikimi, T1
Matsuoka, H1
Ishikawa, K1
Yoshihara, F1
Kawano, Y1
Kitamura, K1
Saito, Y1
Kangawa, K1
Matsuo, H1
Omae, T1

Reviews

1 review available for nicardipine and Left Ventricular Hypertrophy

ArticleYear
Therapeutic advances in the treatment of left ventricular hypertrophy.
    European heart journal, 1993, Volume: 14 Suppl D

    Topics: Animals; Antihypertensive Agents; Heart Failure; Hemodynamics; Humans; Hypertension; Hypertrophy, Le

1993

Trials

3 trials available for nicardipine and Left Ventricular Hypertrophy

ArticleYear
Cardioprotective effect of an L/N-type calcium channel blocker in patients with hypertensive heart disease.
    Journal of cardiology, 2009, Volume: 54, Issue:2

    Topics: Adult; Aged; Calcium Channel Blockers; Dihydropyridines; Female; Heart; Humans; Hypertension; Hypert

2009
Effects of four antihypertensive monotherapies on cardiac mass and function in hypertensive patients with left ventricular hypertrophy: randomized prospective study.
    Croatian medical journal, 2002, Volume: 43, Issue:6

    Topics: Adult; Aged; Antihypertensive Agents; Chlorthalidone; Croatia; Echocardiography; Female; Heart Ventr

2002
Both a calcium antagonist and ACE inhibitor reverse hypertrophy in hypertension but a calcium antagonist also depresses contractility.
    Cardiovascular drugs and therapy, 1997, Volume: 11, Issue:1

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Captopril; Double-B

1997

Other Studies

2 other studies available for nicardipine and Left Ventricular Hypertrophy

ArticleYear
Effects of long-term treatment with sustained-release nicardipine on left ventricular hypertrophy and function in patients with essential hypertension.
    Journal of clinical pharmacology, 1994, Volume: 34, Issue:3

    Topics: Aged; Delayed-Action Preparations; Humans; Hypertension; Hypertrophy, Left Ventricular; Middle Aged;

1994
Antihypertensive therapy reduces increased plasma levels of adrenomedullin and brain natriuretic peptide concomitant with regression of left ventricular hypertrophy in a patient with malignant hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 1996, Volume: 19, Issue:2

    Topics: Adrenomedullin; Antihypertensive Agents; Atrial Fibrillation; Blood Pressure; Echocardiography; Elec

1996