nicardipine has been researched along with Labor, Premature in 17 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our results suggest that long-term treatment with nicardipine for severe pre-eclampsia is as effective and safe as a short- and medium-term treatment." | 9.10 | Long-term treatment with nicardipine for severe pre-eclampsia. ( Kinoshita, K; Seki, H; Takeda, S, 2002) |
| "We report three cases of acute pulmonary edema that occurred during treatment by intravenous tocolysis using nicardipine in twin pregnancy patients with no previous heart problems." | 7.75 | [Acute pulmonary edema occurred during tocolytic treatment using nicardipine in a twin pregnancy. Report of three cases]. ( Caroit, Y; Demeure, D; Desjars, P; Esbelin, J; Le Trong, A; Philippe, HJ; Pigeau, H; Winer, N, 2009) |
| "We report the case of a 38-year-old parturient at 30 weeks 2 days term of a multiple pregnancy who experienced acute pulmonary edema more than 48 hours after tocolytic treatment with nicardipine and salbutamol." | 7.73 | [Acute pulmonary edema during nicardipine and salbutamol therapy for preterm labor in twin pregnancy]. ( Chapuis, C; Debaty, G; Koch, FX; Menthonnex, E; Menthonnex, P; Pons, JC; Rancurel, E, 2005) |
| " We report three cases of pulmonary edema during preterm labor associated with the use of calcium channel blocker, intravenous nicardipine, widely used for tocolysis in France." | 7.73 | [Acute pulmonary edema during preterm labor: role of nicardipine tocolysis (three cases)]. ( Apfelbaum, D; Boccara, F; Carbonne, B; Cohen, A; Janower, S; Lejeune, V, 2005) |
| " In nicardipine group, the pregnancy was prolonged more than 48 hours in 87." | 5.13 | Nicardipine versus salbutamol in the treatment of premature labor: comparison of their efficacy and side effects. ( Abdennadheur, W; Amouri, H; Ben Amar, H; Gargouri, A; Guermazi, M; Hadj Taib, H; Kallel, W; Trabelsi, K; Zribi, A, 2008) |
| "Our results suggest that long-term treatment with nicardipine for severe pre-eclampsia is as effective and safe as a short- and medium-term treatment." | 5.10 | Long-term treatment with nicardipine for severe pre-eclampsia. ( Kinoshita, K; Seki, H; Takeda, S, 2002) |
| "We report three cases of acute pulmonary edema that occurred during treatment by intravenous tocolysis using nicardipine in twin pregnancy patients with no previous heart problems." | 3.75 | [Acute pulmonary edema occurred during tocolytic treatment using nicardipine in a twin pregnancy. Report of three cases]. ( Caroit, Y; Demeure, D; Desjars, P; Esbelin, J; Le Trong, A; Philippe, HJ; Pigeau, H; Winer, N, 2009) |
| "We report the case of a 38-year-old parturient at 30 weeks 2 days term of a multiple pregnancy who experienced acute pulmonary edema more than 48 hours after tocolytic treatment with nicardipine and salbutamol." | 3.73 | [Acute pulmonary edema during nicardipine and salbutamol therapy for preterm labor in twin pregnancy]. ( Chapuis, C; Debaty, G; Koch, FX; Menthonnex, E; Menthonnex, P; Pons, JC; Rancurel, E, 2005) |
| " We report three cases of pulmonary edema during preterm labor associated with the use of calcium channel blocker, intravenous nicardipine, widely used for tocolysis in France." | 3.73 | [Acute pulmonary edema during preterm labor: role of nicardipine tocolysis (three cases)]. ( Apfelbaum, D; Boccara, F; Carbonne, B; Cohen, A; Janower, S; Lejeune, V, 2005) |
| "Oral nicardipine is an effective, safe, and well-tolerated tocolytic agent." | 2.69 | Oral nicardipine versus intravenous magnesium sulfate for the treatment of preterm labor. ( Dickerson, GA; Fischer, RG; Larmon, JE; May, WL; Morrison, JC; Ross, BS, 1999) |
| "Nicardipine is a tocolytic agent as effective as salbutamol in the treatment of premature labor." | 2.68 | Nicardipine versus salbutamol in the treatment of premature labor. A prospective randomized study. ( Abankwa, A; Carbonne, B; Guyard, B; Jannet, D; Marpeau, L; Milliez, J, 1997) |
| "We report here four cases of pulmonary edema in pregnant women treated with nicardipine (Loxen) for preterm labor." | 1.34 | [Pulmonary edema during calcium-channel blockers therapy: role of predisposing or pharmacologic factors?]. ( Akerman, G; Cabrol, D; Goffinet, F; Jacqmin, S; Mignon, A; Tsatsaris, V, 2007) |
| "Similarly, when premature labor was induced by ovariectomy (OVX) on day 16, OVX control rats (n = 6) receiving 5 microgram/day of estradiol delivered 82% of the fetuses within 48 hours of OVX, whereas the rats treated with nicardipine (n = 7) delivered only 4% of the fetuses." | 1.26 | Deactivation of the uterus during normal and premature labor by the calcium antagonist nicardipine. ( Csapo, AI; Henzl, MR; Puri, CP; Tarro, S, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.76) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 9 (52.94) | 29.6817 |
| 2010's | 4 (23.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zieleskiewicz, L | 1 |
| Boustiere, V | 1 |
| Bourgoin, A | 1 |
| Hammad, E | 1 |
| Leone, M | 1 |
| Bretelle, F | 1 |
| Bejan-Angoulvant, T | 1 |
| Crochet, J | 1 |
| Jonville-Bera, AP | 1 |
| Philippe, HJ | 1 |
| Le Trong, A | 1 |
| Pigeau, H | 1 |
| Demeure, D | 1 |
| Desjars, P | 1 |
| Esbelin, J | 1 |
| Caroit, Y | 1 |
| Winer, N | 1 |
| Trabelsi, K | 1 |
| Hadj Taib, H | 1 |
| Amouri, H | 1 |
| Abdennadheur, W | 1 |
| Ben Amar, H | 1 |
| Kallel, W | 1 |
| Zribi, A | 1 |
| Gargouri, A | 1 |
| Guermazi, M | 1 |
| Laas, E | 1 |
| Deis, S | 1 |
| Haddad, B | 1 |
| Kayem, G | 1 |
| Vaast, P | 1 |
| Dubreucq-Fossaert, S | 1 |
| Houfflin-Debarge, V | 1 |
| Provost-Helou, N | 1 |
| Ducloy-Bouthors, AS | 1 |
| Puech, F | 1 |
| Subtil, D | 1 |
| Carbonne, B | 4 |
| Papatsonis, DN | 1 |
| Flenady, VJ | 1 |
| Dekker, GA | 1 |
| King, JF | 1 |
| Chapuis, C | 1 |
| Menthonnex, E | 1 |
| Debaty, G | 1 |
| Koch, FX | 1 |
| Rancurel, E | 1 |
| Menthonnex, P | 1 |
| Pons, JC | 1 |
| Janower, S | 1 |
| Lejeune, V | 1 |
| Apfelbaum, D | 1 |
| Boccara, F | 1 |
| Cohen, A | 1 |
| Akerman, G | 1 |
| Mignon, A | 1 |
| Tsatsaris, V | 1 |
| Jacqmin, S | 1 |
| Cabrol, D | 1 |
| Goffinet, F | 1 |
| Csapo, AI | 1 |
| Puri, CP | 1 |
| Tarro, S | 1 |
| Henzl, MR | 1 |
| Jannet, D | 1 |
| Abankwa, A | 1 |
| Guyard, B | 1 |
| Marpeau, L | 1 |
| Milliez, J | 1 |
| Larmon, JE | 1 |
| Ross, BS | 1 |
| May, WL | 1 |
| Dickerson, GA | 1 |
| Fischer, RG | 1 |
| Morrison, JC | 1 |
| Seki, H | 1 |
| Takeda, S | 1 |
| Kinoshita, K | 1 |
| Ducsay, CA | 1 |
| Thompson, JS | 1 |
| Wu, AT | 1 |
| Novy, MJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Double-Blinded Trial of Magnesium Sulfate Tocolysis Versus Nifedipine Tocolysis in Women With Preterm Labor Between 24 to 32 6/7 Weeks' Gestation[NCT00306462] | 33 participants (Actual) | Interventional | 2006-03-31 | Terminated (stopped due to No enrollment in past year, lack of interest) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for nicardipine and Labor, Premature
| Article | Year |
|---|---|
[Calcium channel blockers pharmacology and their use as tocolytics].
Topics: Adult; Calcium Channel Blockers; Female; Humans; Nicardipine; Nifedipine; Obstetric Labor, Premature | 2015 |
4 trials available for nicardipine and Labor, Premature
| Article | Year |
|---|---|
Nicardipine versus salbutamol in the treatment of premature labor: comparison of their efficacy and side effects.
Topics: Adult; Albuterol; Female; Humans; Nicardipine; Obstetric Labor, Premature; Pregnancy; Prospective St | 2008 |
Nicardipine versus salbutamol in the treatment of premature labor. A prospective randomized study.
Topics: Adult; Albuterol; Calcium Channel Blockers; Female; Follow-Up Studies; Humans; Nicardipine; Obstetri | 1997 |
Oral nicardipine versus intravenous magnesium sulfate for the treatment of preterm labor.
Topics: Administration, Oral; Adult; Female; Humans; Infusions, Intravenous; Magnesium Sulfate; Nicardipine; | 1999 |
Long-term treatment with nicardipine for severe pre-eclampsia.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Drug Administration Schedule; Female; Gestational Ag | 2002 |
12 other studies available for nicardipine and Labor, Premature
| Article | Year |
|---|---|
Nicardipine and preterm labour: pulmonary oedema.
Topics: Calcium Channel Blockers; Female; Humans; Infant, Newborn; Nicardipine; Obstetric Labor, Premature; | 2014 |
Nicardipine-associated pulmonary edema in a parturient: use of chest ultrasound.
Topics: Adult; Calcium Channel Blockers; Female; Humans; Nicardipine; Obstetric Labor, Premature; Pregnancy; | 2014 |
[Acute pulmonary edema occurred during tocolytic treatment using nicardipine in a twin pregnancy. Report of three cases].
Topics: Adult; Diagnosis, Differential; Female; Humans; Nicardipine; Obstetric Labor, Premature; Pregnancy; | 2009 |
[Comparison of the rate of maternal complications of nifedipine and nicardipine in cases of preterm labor: historical study on two consecutive periods].
Topics: Adult; Calcium Channel Blockers; Female; France; Humans; Nicardipine; Nifedipine; Obstetric Labor, P | 2012 |
Acute pulmonary oedema during nicardipine therapy for premature labour; Report of five cases.
Topics: Adult; Diagnosis, Differential; Female; Humans; Nicardipine; Obstetric Labor, Premature; Pregnancy; | 2004 |
Comment on the article "Acute pulmonary oedema during nicardipine therapy for premature labour. Report of five cases" by Vaast P., et al. [Eur J Obstet Gynecol Reprod Biol 2004;113:98-9].
Topics: Calcium Channel Blockers; Female; Humans; Nicardipine; Nifedipine; Obstetric Labor, Premature; Pregn | 2005 |
[Acute pulmonary edema during nicardipine and salbutamol therapy for preterm labor in twin pregnancy].
Topics: Adult; Albuterol; Female; Gestational Age; Humans; Nicardipine; Obstetric Labor, Premature; Pregnanc | 2005 |
[Acute pulmonary edema during preterm labor: role of nicardipine tocolysis (three cases)].
Topics: Acute Disease; Adrenergic beta-Agonists; Adult; Calcium Channel Blockers; Drug Interactions; Female; | 2005 |
[Tocolysis with nifedipine: its use in current practice. Gynecol Obstet Fertil 2005;33:483-7].
Topics: Female; Humans; Nicardipine; Nifedipine; Obstetric Labor, Premature; Pregnancy; Pregnancy Outcome; P | 2006 |
[Pulmonary edema during calcium-channel blockers therapy: role of predisposing or pharmacologic factors?].
Topics: Adult; Calcium Channel Blockers; Diabetes Mellitus, Type 1; Diseases in Twins; Female; Fetofetal Tra | 2007 |
Deactivation of the uterus during normal and premature labor by the calcium antagonist nicardipine.
Topics: Animals; Calcium Channel Blockers; Female; Labor, Obstetric; Nicardipine; Nifedipine; Obstetric Labo | 1982 |
Effects of calcium entry blocker (nicardipine) tocolysis in rhesus macaques: fetal plasma concentrations and cardiorespiratory changes.
Topics: Animals; Female; Fetal Blood; Fetus; Macaca mulatta; Maternal-Fetal Exchange; Nicardipine; Obstetric | 1987 |