nicardipine has been researched along with Intraocular Pressure in 8 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the possible role of calcium channel blocker on changes in aqueous flare and intraocular pressure induced by prostaglandin E2 (PGE2) in pigmented rabbits, we examined the effects of nilvadipine and nicardipine (calcium channel blockers)." | 7.70 | Nilvadipine inhibits acute rise of aqueous flare and intraocular pressure induced by prostaglandin E2 in pigmented rabbits. ( Hayasaka, S; Hiraki, S; Zhang, XY, 1998) |
| "The effects of nicardipine hydrochloride (NH), a calcium channel blocker, on the intraocular pressure (IOP) and aqueous humor dynamics were studied in the rabbit eye." | 7.68 | [Effect of the calcium channel blocker nicardipine on intraocular pressure and aqueous humor dynamics in rabbit]. ( Sasaki, T, 1993) |
| " To evaluate the effects of dihydropyridine calcium channel blocker and nonselective beta-adrenergic antagonist on ocular perfusion, we investigated the short-term effects of single oral doses of nicardipine (40 mg) and propranolol (40 mg) on the blood flow velocity in the ophthalmic artery, intraocular pressure (IOP), systemic blood pressure, and heart rate in nine healthy Japanese male volunteers in a double-blind, placebo-controlled study using color Doppler imaging." | 5.08 | Short-term effects of nicardipine and propranolol on ocular and systemic hemodynamics in healthy Japanese subjects. ( Kotegawa, T; Matsukubo, S; Nakamura, K; Nakano, S; Nakatsuka, K; Tsutsumi, K; Yatsuka, YI, 1998) |
| "Timolol is widely used for the topical therapy of glaucoma." | 5.08 | Interaction between timolol eyedrops and oral nicardipine or oral diltiazem in healthy Japanese subjects. ( Kotegawa, T; Nakamura, K; Nakano, S; Nakatsuka, K; Tsutsumi, K; Yatsuka, YI, 1998) |
| "To evaluate the possible role of calcium channel blocker on changes in aqueous flare and intraocular pressure induced by prostaglandin E2 (PGE2) in pigmented rabbits, we examined the effects of nilvadipine and nicardipine (calcium channel blockers)." | 3.70 | Nilvadipine inhibits acute rise of aqueous flare and intraocular pressure induced by prostaglandin E2 in pigmented rabbits. ( Hayasaka, S; Hiraki, S; Zhang, XY, 1998) |
| "The authors evaluated the systemic and ocular hypotensive effects of nicardipine hydrochloride (Perdipine:NH) in 31 cases with acute hypertension (over 160/95 mmHg) during cataract surgery." | 3.68 | [Control of blood pressure by a calcium antagonist during cataract surgery]. ( Amemiya, T; Imai, M; Kato, Y; Sasaki, T, 1992) |
| "Intraocular pressure was reduced as the time passed." | 1.29 | [Effect of endothelin-1 on ocular circulation]. ( Azuma, I; Hamada, J; Moriya, S; Oku, H; Shimizu, K; Sugiyama, T, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maetani, S | 1 |
| Sugiyama, T | 2 |
| Oku, H | 2 |
| Shimamura, I | 1 |
| Shimizu, K | 2 |
| Hamada, J | 2 |
| Moriya, S | 2 |
| Kaji, Y | 1 |
| Hiraki, S | 2 |
| Hirata, H | 1 |
| Sasaki, T | 2 |
| Azuma, I | 1 |
| Yatsuka, YI | 2 |
| Matsukubo, S | 1 |
| Tsutsumi, K | 2 |
| Kotegawa, T | 2 |
| Nakamura, K | 2 |
| Nakano, S | 2 |
| Nakatsuka, K | 2 |
| Zhang, XY | 1 |
| Hayasaka, S | 1 |
| Kato, Y | 1 |
| Imai, M | 1 |
| Amemiya, T | 1 |
2 trials available for nicardipine and Intraocular Pressure
| Article | Year |
|---|---|
Short-term effects of nicardipine and propranolol on ocular and systemic hemodynamics in healthy Japanese subjects.
Topics: Adrenergic beta-Antagonists; Adult; Calcium Channel Blockers; Double-Blind Method; Hemodynamics; Hum | 1998 |
Interaction between timolol eyedrops and oral nicardipine or oral diltiazem in healthy Japanese subjects.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Asian People; Blood Pressure; Diltiazem; D | 1998 |
6 other studies available for nicardipine and Intraocular Pressure
| Article | Year |
|---|---|
[Effect of systemic calcium antagonist on a model of ocular circulation disturbance induced by endothelin-1].
Topics: Animals; Blood Pressure; Endothelins; Evoked Potentials, Visual; Intraocular Pressure; Nicardipine; | 1995 |
[The effects of calcium antagonists on prostaglandin E2 reaction in rabbit eyes].
Topics: Animals; Aqueous Humor; Calcium Channel Blockers; Diltiazem; Dinoprostone; Eye; Eye Proteins; Intrao | 1994 |
[Effect of the calcium channel blocker nicardipine on intraocular pressure and aqueous humor dynamics in rabbit].
Topics: Animals; Aqueous Humor; Intraocular Pressure; Male; Nicardipine; Rabbits | 1993 |
[Effect of endothelin-1 on ocular circulation].
Topics: Animals; Choroid; Endothelins; Intraocular Pressure; Nicardipine; Optic Nerve; Rabbits; Regional Blo | 1993 |
Nilvadipine inhibits acute rise of aqueous flare and intraocular pressure induced by prostaglandin E2 in pigmented rabbits.
Topics: Animals; Anterior Eye Segment; Aqueous Humor; Calcium Channel Blockers; Dinoprostone; Dose-Response | 1998 |
[Control of blood pressure by a calcium antagonist during cataract surgery].
Topics: Aged; Aged, 80 and over; Blood Pressure; Cataract; Cataract Extraction; Female; Humans; Hypertension | 1992 |