Page last updated: 2024-11-01

nicardipine and Intermittent Claudication

nicardipine has been researched along with Intermittent Claudication in 2 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Intermittent Claudication: A symptom complex characterized by pain and weakness in SKELETAL MUSCLE group associated with exercise, such as leg pain and weakness brought on by walking. Such muscle limpness disappears after a brief rest and is often relates to arterial STENOSIS; muscle ISCHEMIA; and accumulation of LACTATE.

Research Excerpts

ExcerptRelevanceReference
"The effects of two potent vasodilating drugs, captopril (C) (25 mg tid), nicardipine (N) (20 mg tid), and placebo (P) were evaluated and compared, in 10 men (mean age of sixty-five years) with intermittent claudication from moderate to severe multilevel chronic occlusive arterial disease (COAD) of the lower extremity, by use of the Doppler ultrasonic method, at rest and after Carter's exercise test."5.06Assessment of captopril and nicardipine effects on chronic occlusive arterial disease of the lower extremity using Doppler ultrasound. ( Bartoli, P; Bernardi, D; Ferreri, A; Geri, AB; Ieri, A, 1988)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
O'Brien, JR1
Etherington, MD1
Salmon, GP1
McNally, S1
Bernardi, D1
Bartoli, P1
Ferreri, A1
Geri, AB1
Ieri, A1

Trials

1 trial available for nicardipine and Intermittent Claudication

ArticleYear
Assessment of captopril and nicardipine effects on chronic occlusive arterial disease of the lower extremity using Doppler ultrasound.
    Angiology, 1988, Volume: 39, Issue:11

    Topics: Arterial Occlusive Diseases; Blood Flow Velocity; Captopril; Clinical Trials as Topic; Double-Blind

1988

Other Studies

1 other study available for nicardipine and Intermittent Claudication

ArticleYear
The influence of nicardipine on platelet tests in patients with claudication.
    Thrombosis research, 1990, Apr-01, Volume: 58, Issue:1

    Topics: Aged; Blood Platelets; Female; Humans; Intermittent Claudication; Male; Nicardipine; Platelet Functi

1990