nicardipine has been researched along with Injury, Myocardial Reperfusion in 7 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was designed to investigate whether two L-type calcium antagonists, verapamil and nicardipine reduce the myocardial necrosis (infarct size) following ischemia and reperfusion." | 7.70 | [Comparison of effects of verapamil and those of nicardipine on myocardial ischemia and reperfusion injury: a study in an in situ rabbit model]. ( Furuya, M; Yoshida, K, 1999) |
| "This study was designed to investigate whether two L-type calcium antagonists, verapamil and nicardipine reduce the myocardial necrosis (infarct size) following ischemia and reperfusion." | 3.70 | [Comparison of effects of verapamil and those of nicardipine on myocardial ischemia and reperfusion injury: a study in an in situ rabbit model]. ( Furuya, M; Yoshida, K, 1999) |
| "Nicardipine is a potent coronary and systemic vasodilator without depression of ventricular function." | 1.32 | Nicardipine augments local myocardial perfusion after coronary artery reperfusion in dogs. ( Jang, YH; Kim, JM, 2003) |
| "Nicardipine-treated and control groups had similar jeopardy area values (41." | 1.28 | Effects of nicardipine, a calcium antagonist, on myocardial salvage and high energy phosphate stores in reperfused myocardial injury. ( Derugin, N; Higgins, CB; Holt, WW; Saeed, M; Wendland, MF; Wolfe, C, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 5 (71.43) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jang, YH | 1 |
| Kim, JM | 1 |
| Tanonaka, K | 1 |
| Kajiwara, H | 1 |
| Kameda, H | 1 |
| Takasaki, A | 1 |
| Takeo, S | 1 |
| Furuya, M | 1 |
| Yoshida, K | 1 |
| Mitchell, ME | 1 |
| DeBoer, DA | 1 |
| Crittenden, MD | 1 |
| Clark, RE | 1 |
| Sullivan, AT | 1 |
| Baker, DJ | 1 |
| Drew, GM | 1 |
| Holt, WW | 1 |
| Wendland, MF | 1 |
| Derugin, N | 1 |
| Wolfe, C | 1 |
| Saeed, M | 1 |
| Higgins, CB | 1 |
| Koolen, JJ | 1 |
| van Wezel, HB | 1 |
| Visser, CA | 1 |
| Moulijn, AC | 1 |
| Leyssius, AT | 1 |
| van Hal, JM | 1 |
| Deen, L | 1 |
| Dunning, AJ | 1 |
1 trial available for nicardipine and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Nicardipine for preservation of myocardial metabolism and function in patients undergoing coronary artery surgery.
Topics: Aged; Cardioplegic Solutions; Coronary Vessels; Extracorporeal Circulation; Heart; Hemodynamics; Hum | 1989 |
6 other studies available for nicardipine and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Nicardipine augments local myocardial perfusion after coronary artery reperfusion in dogs.
Topics: Animals; Coronary Circulation; Dogs; Drug Evaluation, Preclinical; Myocardial Reperfusion; Myocardia | 2003 |
Relationship between myocardial cation content and injury in reperfused rat hearts treated with cation channel blockers.
Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Cations; Creatine Kinase; Diltiazem; Dose | 1999 |
[Comparison of effects of verapamil and those of nicardipine on myocardial ischemia and reperfusion injury: a study in an in situ rabbit model].
Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Disease Models, Animal; Myocardial Ischem | 1999 |
Nicardipine: myocardial protection in isolated working hearts.
Topics: Animals; Cardioplegic Solutions; Heart; Heart Arrest, Induced; Hemodynamics; Hypothermia, Induced; I | 1992 |
Effect of calcium channel blocking agents on infarct size after ischaemia-reperfusion in anaesthetised pigs: relationship between cardioprotection and cardiodepression.
Topics: Animals; Aspirin; Coronary Vessels; Depression, Chemical; Heart; Hemodynamics; Injections, Intra-Art | 1991 |
Effects of nicardipine, a calcium antagonist, on myocardial salvage and high energy phosphate stores in reperfused myocardial injury.
Topics: Adenosine Triphosphate; Animals; Cats; Magnetic Resonance Spectroscopy; Myocardial Infarction; Myoca | 1990 |