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nicardipine and Injury, Ischemia-Reperfusion

nicardipine has been researched along with Injury, Ischemia-Reperfusion in 8 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Research Excerpts

ExcerptRelevanceReference
"To study the effects of tetrandrine (Tet) vs nicardipine (Nic) on cerebral ischemia-reperfusion damages."7.69Tetrandrine vs nicardipine in cerebral ischemia-reperfusion damages in gerbils. ( Liu, TP; Sun, F, 1995)
"To study the effects of tetrandrine (Tet) vs nicardipine (Nic) on cerebral ischemia-reperfusion damages."3.69Tetrandrine vs nicardipine in cerebral ischemia-reperfusion damages in gerbils. ( Liu, TP; Sun, F, 1995)
"We investigated the effect of nicardipine (NC), a calcium antagonist, on retinal ischemia-reperfusion injury."3.69[The effect of calcium antagonist on ischemia-reperfusion injury of the rabbit retina]. ( Gotoh, T; Hosobe, Y; Kato, C; Mori, T; Sugawara, T; Tazawa, Y, 1996)
"Nicardipine treatment normalized PDH activity quickly and improved energy metabolism after reperfusion."1.30Effect of nicardipine, a Ca2+ channel blocker, on pyruvate dehydrogenase activity and energy metabolites during cerebral ischemia and reperfusion in gerbil brain. ( Fukuchi, T; Katayama, Y; McKee, A; Terashi, A, 1998)
"Nicardipine pretreatment attenuated the increase in LDH level, perfusion pressure and intrahepatic volumes after reoxygenation, but there were no difference in liver microcirculation during 120-min hypoxia."1.28Influence of nicardipine on post-hypoxic injury in the isolated perfused rat liver. ( Fujita, Y; Kimura, K; Takaori, M, 1991)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (87.50)18.2507
2000's0 (0.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Raveh, Y1
Lubarsky, DA1
Pretto, EA1
Proctor, KG1
Kuzu, MA1
Köksoy, C1
Alaçayr, I1
Yazar, O1
Kuterdem, E1
Sun, F1
Liu, TP1
Mori, T1
Sugawara, T1
Hosobe, Y1
Gotoh, T1
Kato, C1
Tazawa, Y1
Kittaka, M1
Giannotta, SL1
Zelman, V1
Correale, JD1
DeGiorgio, CM1
Weiss, MH1
Zlokovic, BV1
Katayama, Y1
Fukuchi, T1
McKee, A1
Terashi, A1
Fujita, Y1
Kimura, K1
Takaori, M1
Hano, O1
Silverman, HS1
Blank, PS1
Mellits, ED1
Baumgardner, R1
Lakatta, EG1
Stern, MD1

Other Studies

8 other studies available for nicardipine and Injury, Ischemia-Reperfusion

ArticleYear
Nicardipine reverses vasoactivity associated with University of Wisconsin solution in the rat peripheral circulation.
    Transplantation proceedings, 2011, Volume: 43, Issue:7

    Topics: Adenosine; Allopurinol; Animals; Glutathione; Insulin; Male; Microcirculation; Nicardipine; Organ Pr

2011
The effect of nicardipine on renal functions following 72-hour cold ischemia.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1995, Volume: 27, Issue:5

    Topics: Animals; Calcium Channel Blockers; Cold Temperature; Female; Kidney; Male; Nicardipine; Rabbits; Rep

1995
Tetrandrine vs nicardipine in cerebral ischemia-reperfusion damages in gerbils.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1995, Volume: 16, Issue:2

    Topics: Alkaloids; Animals; Benzylisoquinolines; Brain; Brain Ischemia; Calcium; Calcium Channel Blockers; E

1995
[The effect of calcium antagonist on ischemia-reperfusion injury of the rabbit retina].
    Nippon Ganka Gakkai zasshi, 1996, Volume: 100, Issue:10

    Topics: Animals; Calcium Channel Blockers; Electroretinography; Ischemia; Nicardipine; Rabbits; Reperfusion

1996
Attenuation of brain injury and reduction of neuron-specific enolase by nicardipine in systemic circulation following focal ischemia and reperfusion in a rat model.
    Journal of neurosurgery, 1997, Volume: 87, Issue:5

    Topics: Animals; Cerebral Infarction; Cerebrovascular Circulation; Disease Models, Animal; Ischemic Attack,

1997
Effect of nicardipine, a Ca2+ channel blocker, on pyruvate dehydrogenase activity and energy metabolites during cerebral ischemia and reperfusion in gerbil brain.
    Brain research, 1998, Jan-19, Volume: 781, Issue:1-2

    Topics: Animals; Calcium Channel Blockers; Energy Metabolism; Gerbillinae; Ischemic Attack, Transient; Male;

1998
Influence of nicardipine on post-hypoxic injury in the isolated perfused rat liver.
    Resuscitation, 1991, Volume: 22, Issue:3

    Topics: Animals; Cell Hypoxia; Indicator Dilution Techniques; L-Lactate Dehydrogenase; Liver; Liver Circulat

1991
Nicardipine prevents calcium loading and "oxygen paradox" in anoxic single rat myocytes by a mechanism independent of calcium channel blockade.
    Circulation research, 1991, Volume: 69, Issue:6

    Topics: Animals; Calcium; Cell Survival; Coronary Disease; Dose-Response Relationship, Drug; Hypoxia; In Vit

1991