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nicardipine and Inflammation

nicardipine has been researched along with Inflammation in 5 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"The present study is the first to report a novel inhibitory role of nicardipine on neuroinflammation and provides a new candidate agent for the development of therapies for inflammation-related neurodegenerative diseases."3.80Anti-neuroinflammatory effects of the calcium channel blocker nicardipine on microglial cells: implications for neuroprotection. ( Chang, PC; Hsu, HC; Huang, BR; Huang, SS; Ko, PY; Lee, CH; Lin, C; Lin, HY; Liu, YS; Lu, DY; Tsai, CF; Wu, CY; Yeh, WL, 2014)
"We tested the effect of nicardipine in experimental allergic asthma."3.74Calcium channel blocker prevents T helper type 2 cell-mediated airway inflammation. ( Cabral, MD; Druet, P; Gallard, A; Gomes, B; Guéry, JC; Leclerc, C; Mariamé, B; Moreau, M; Paulet, P; Pelletier, L; Savignac, M, 2007)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, BR1
Chang, PC1
Yeh, WL1
Lee, CH1
Tsai, CF1
Lin, C1
Lin, HY1
Liu, YS1
Wu, CY1
Ko, PY1
Huang, SS1
Hsu, HC1
Lu, DY1
Halici, Z1
Suleyman, H1
Cadirci, E1
Gomes, B1
Cabral, MD1
Gallard, A1
Savignac, M1
Paulet, P1
Druet, P1
Mariamé, B1
Moreau, M1
Leclerc, C1
Guéry, JC1
Pelletier, L1
Gürdal, H1
Sara, Y1
Tulunay, FC1
Chen, WR1
Yang, YX1
Zheng, HQ1
A, SY1
Liu, F1

Other Studies

5 other studies available for nicardipine and Inflammation

ArticleYear
Anti-neuroinflammatory effects of the calcium channel blocker nicardipine on microglial cells: implications for neuroprotection.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cell Line; Cytokines; Gene Expression Regulation;

2014
Effects of calcium channel blockers on hyaluronidase-induced capillary vascular permeability.
    Archives of pharmacal research, 2008, Volume: 31, Issue:7

    Topics: Amlodipine; Animals; Calcium Channel Blockers; Capillary Permeability; Carrageenan; Dihydropyridines

2008
Calcium channel blocker prevents T helper type 2 cell-mediated airway inflammation.
    American journal of respiratory and critical care medicine, 2007, Jun-01, Volume: 175, Issue:11

    Topics: Administration, Intranasal; Animals; Asthma; Bronchoalveolar Lavage Fluid; Calcium; Calcium Channel

2007
Effects of calcium channel blockers on formalin-induced nociception and inflammation in rats.
    Pharmacology, 1992, Volume: 44, Issue:5

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Diltiazem; F

1992
[Anti-inflammatory effects of verapamil, nifedipine and nicardipine].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1990, Volume: 11, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Dinoprostone; Female; Infl

1990