nicardipine has been researched along with Hypoxia in 13 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The anti-ischemic and anti-anoxic effects of efonidipine, a dihydropyridine calcium antagonist, were studied in several models for cerebral ischemia and anoxia in mice and rats, and the effects were compared with those of nicardipine and flunarizine." | 7.69 | [Effect of efonidipine hydrochloride, a calcium channel blocker, on the experimental cerebral ischemia/anoxia]. ( Furuichi, H; Ito, S; Izumi, J; Kurimoto, T; Matsumura, T; Mori, T; Nishi, N; Suda, H; Takei, M; Tanaka, Y, 1995) |
| " The effects of the calcium channel blockers, nicardipine and ifenprodil, on the brain free arachidonic acid level and learning ability in rats exposed to hypoxia were examined." | 7.69 | The influence of nicardipine and ifenprodil on the brain free arachidonic acid level and behavior in hypoxia-exposed rats. ( Eraković, V; Mrsić, J; Simonić, A; Varljen, J; Zupan, G, 1997) |
| "Nicardipine is a commonly used anti-hypertensive drug for acute situations." | 5.38 | [Nicardipine induced hypoxia: role of hypoxic pulmonary vasoconstriction]. ( Bordes, J; Cotte, J; D'Aranda, E; Esnault, P; Meaudre, E, 2012) |
| "The anti-ischemic and anti-anoxic effects of efonidipine, a dihydropyridine calcium antagonist, were studied in several models for cerebral ischemia and anoxia in mice and rats, and the effects were compared with those of nicardipine and flunarizine." | 3.69 | [Effect of efonidipine hydrochloride, a calcium channel blocker, on the experimental cerebral ischemia/anoxia]. ( Furuichi, H; Ito, S; Izumi, J; Kurimoto, T; Matsumura, T; Mori, T; Nishi, N; Suda, H; Takei, M; Tanaka, Y, 1995) |
| " The effects of the calcium channel blockers, nicardipine and ifenprodil, on the brain free arachidonic acid level and learning ability in rats exposed to hypoxia were examined." | 3.69 | The influence of nicardipine and ifenprodil on the brain free arachidonic acid level and behavior in hypoxia-exposed rats. ( Eraković, V; Mrsić, J; Simonić, A; Varljen, J; Zupan, G, 1997) |
| "Nicardipine is a commonly used anti-hypertensive drug for acute situations." | 1.38 | [Nicardipine induced hypoxia: role of hypoxic pulmonary vasoconstriction]. ( Bordes, J; Cotte, J; D'Aranda, E; Esnault, P; Meaudre, E, 2012) |
| " After dosing with nicardipine, the results differed according to the exploratory technique: a slight increase of the laser Doppler signal (NS) and a decrease of the photoplethysmographic signal were recorded." | 1.27 | [Photoplethysmography and laser Doppler velocimetry in the study of cutaneous vasomotility at high altitudes]. ( Kayser, B; Keromes, A; Larmignat, P; Pecquet, C; Richalet, JP, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 7 (53.85) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Chrétien, B | 1 |
| Decros, JB | 1 |
| Suard, F | 1 |
| Dolladille, C | 1 |
| Fischer, MO | 1 |
| Alexandre, J | 1 |
| Descamps, R | 1 |
| Aoshima, D | 1 |
| Murata, T | 1 |
| Hori, M | 1 |
| Ozaki, H | 1 |
| Cotte, J | 1 |
| D'Aranda, E | 1 |
| Esnault, P | 1 |
| Bordes, J | 1 |
| Meaudre, E | 1 |
| Matsumura, T | 1 |
| Furuichi, H | 1 |
| Izumi, J | 1 |
| Suda, H | 1 |
| Ito, S | 1 |
| Takei, M | 1 |
| Nishi, N | 1 |
| Mori, T | 1 |
| Tanaka, Y | 1 |
| Kurimoto, T | 1 |
| Stadnicka, A | 1 |
| Stekiel, TA | 1 |
| Hogan, QH | 1 |
| Bosnjak, ZJ | 1 |
| Kampine, JP | 1 |
| Benzi, G | 1 |
| Gorini, A | 1 |
| Arnaboldi, R | 1 |
| Ghigini, B | 1 |
| Villa, R | 1 |
| Draper, NJ | 1 |
| Shah, AM | 1 |
| Eraković, V | 1 |
| Zupan, G | 1 |
| Mrsić, J | 1 |
| Simonić, A | 1 |
| Varljen, J | 1 |
| Pape, D | 1 |
| Goineau, S | 1 |
| Guillo, P | 1 |
| Durand-Castel, X | 1 |
| Bellissant, E | 1 |
| Aono, Y | 1 |
| Ariyoshi, H | 1 |
| Sakon, M | 1 |
| Ueda, A | 1 |
| Tsuji, Y | 1 |
| Kawasaki, T | 1 |
| Monden, M | 1 |
| Bartlett, IS | 1 |
| Marshall, JM | 1 |
| Hano, O | 1 |
| Silverman, HS | 1 |
| Blank, PS | 1 |
| Mellits, ED | 1 |
| Baumgardner, R | 1 |
| Lakatta, EG | 1 |
| Stern, MD | 1 |
| Pecquet, C | 1 |
| Richalet, JP | 1 |
| Kayser, B | 1 |
| Larmignat, P | 1 |
| Keromes, A | 1 |
13 other studies available for nicardipine and Hypoxia
| Article | Year |
|---|---|
Hypoxia Associated With Dihydropyridine Calcium Channel Inhibitors: A Pharmacovigilance Study in VigiBase.
Topics: Calcium Channels; Dihydropyridines; Humans; Hypoxia; Nicardipine; Pharmacovigilance; World Health Or | 2023 |
Time-dependent phenotypic and contractile changes of pulmonary artery in chronic hypoxia-induced pulmonary hypertension.
Topics: Actins; Amides; Animals; Cell Proliferation; Endothelin-1; Hypertension, Pulmonary; Hypoxia; Immunoh | 2009 |
[Nicardipine induced hypoxia: role of hypoxic pulmonary vasoconstriction].
Topics: Calcium Channel Blockers; Humans; Hypoxia; Lung; Male; Middle Aged; Nicardipine; Pneumonia; Pulmonar | 2012 |
[Effect of efonidipine hydrochloride, a calcium channel blocker, on the experimental cerebral ischemia/anoxia].
Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Dihydropyridines; Flunarizine; Hypoxia; Male; Mic | 1995 |
Hypoxic contraction of isolated rabbit mesenteric veins. Contribution of endothelium and attenuation by volatile anesthetics.
Topics: Acetylcholine; Animals; Arginine; Endothelium, Vascular; Enflurane; Glycopeptides; Halothane; Hypoxi | 1995 |
Effect of intermittent mild hypoxia and drug treatment on synaptosomal nonmitochondrial ATPase activities.
Topics: Adenosine Triphosphatases; Animals; Cerebral Cortex; Energy Metabolism; Hypoxia; In Vitro Techniques | 1993 |
Beneficial effects of a nitric oxide donor on recovery of contractile function following brief hypoxia in isolated rat heart.
Topics: Adenosine; Animals; Calcium Channel Blockers; Coronary Circulation; Dose-Response Relationship, Drug | 1997 |
The influence of nicardipine and ifenprodil on the brain free arachidonic acid level and behavior in hypoxia-exposed rats.
Topics: Animals; Arachidonic Acid; Brain; Female; Hypoxia; Learning; Nicardipine; Piperidines; Rats; Rats, W | 1997 |
Endothelin, but not angiotensin II, contributes to the hypoxic contractile response of large isolated pulmonary arteries in the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhib | 1999 |
Human umbilical vein endothelial cells (HUVECs) show Ca(2+) mobilization as well as Ca(2+) influx upon hypoxia.
Topics: Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Egtazic Acid; Endothelium, Vas | 2000 |
Analysis of the effects of graded levels of hypoxia on noradrenaline-evoked contraction in the rat iliac artery in vitro.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Calcium; Calcium Channel Blockers; Calcium | 2002 |
Nicardipine prevents calcium loading and "oxygen paradox" in anoxic single rat myocytes by a mechanism independent of calcium channel blockade.
Topics: Animals; Calcium; Cell Survival; Coronary Disease; Dose-Response Relationship, Drug; Hypoxia; In Vit | 1991 |
[Photoplethysmography and laser Doppler velocimetry in the study of cutaneous vasomotility at high altitudes].
Topics: Adult; Altitude Sickness; Female; Humans; Hypoxia; Male; Microcirculation; Middle Aged; Nicardipine; | 1988 |