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nicardipine and Hypotension, Orthostatic

nicardipine has been researched along with Hypotension, Orthostatic in 5 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Hypotension, Orthostatic: A significant drop in BLOOD PRESSURE after assuming a standing position. Orthostatic hypotension is a finding, and defined as a 20-mm Hg decrease in systolic pressure or a 10-mm Hg decrease in diastolic pressure 3 minutes after the person has risen from supine to standing. Symptoms generally include DIZZINESS, blurred vision, and SYNCOPE.

Research Excerpts

ExcerptRelevanceReference
"Nicardipine was given three times a day (mean dose: 69."6.65[Treatment of arterial hypertension in the aged with a calcium antagonist: nicardipine]. ( Bellet, M; Bouchacourt, P; Forette, F; Henry, JF; Hervy, MP; Poyard-Salmeron, C, 1984)
"Orthostatic hypotension is a dangerous problem in elderly patients, often exacerbated by vasodilator medications."2.68Cardiovascular adaptation to orthostatic stress during vasodilator therapy. ( Abernethy, D; Connelly, CM; Kelley-Gagnon, M; Kiely, DK; Lipsitz, LA; Waksmonski, C, 1996)
"Nicardipine was given three times a day (mean dose: 69."2.65[Treatment of arterial hypertension in the aged with a calcium antagonist: nicardipine]. ( Bellet, M; Bouchacourt, P; Forette, F; Henry, JF; Hervy, MP; Poyard-Salmeron, C, 1984)
"Additional factors have been found, ie orthostatic hypotension whatever its mechanism, and association with diuretics, with or without hyponatremia."1.28Dizziness in the elderly and calcium channel antagonists. ( Hugues, FC; Le Jeunne, C; Munera, Y; Ozanne, H, 1991)
" Full PH dose-response curves for standard antihypertensive drugs were explored and were compared to their hypotensive dose-response curves."1.27Antihypertensive drugs: their postural hypotensive effect and their blood pressure lowering activity in conscious normotensive rats. ( Carver, LA; Lee, CH; Strosberg, AM, 1983)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hagiwara, S1
Lee, CH1
Strosberg, AM1
Carver, LA1
Forette, F1
Bellet, M1
Henry, JF1
Hervy, MP1
Poyard-Salmeron, C1
Bouchacourt, P1
Lipsitz, LA1
Connelly, CM1
Kelley-Gagnon, M1
Kiely, DK1
Abernethy, D1
Waksmonski, C1
Le Jeunne, C1
Hugues, FC1
Munera, Y1
Ozanne, H1

Trials

2 trials available for nicardipine and Hypotension, Orthostatic

ArticleYear
[Treatment of arterial hypertension in the aged with a calcium antagonist: nicardipine].
    Archives des maladies du coeur et des vaisseaux, 1984, Volume: 77, Issue:11

    Topics: Aged; Calcium Channel Blockers; Double-Blind Method; Drug Evaluation; Female; Humans; Hypertension;

1984
Cardiovascular adaptation to orthostatic stress during vasodilator therapy.
    Clinical pharmacology and therapeutics, 1996, Volume: 60, Issue:4

    Topics: Aged; Aged, 80 and over; Coronary Disease; Cross-Over Studies; Double-Blind Method; Echocardiography

1996

Other Studies

3 other studies available for nicardipine and Hypotension, Orthostatic

ArticleYear
[Acute poisoning of droxidopa: report of a case].
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2013, Volume: 26, Issue:3

    Topics: Acute Disease; Aged; Antihypertensive Agents; Autonomic Nervous System Diseases; Charcoal; Droxidopa

2013
Antihypertensive drugs: their postural hypotensive effect and their blood pressure lowering activity in conscious normotensive rats.
    Archives internationales de pharmacodynamie et de therapie, 1983, Volume: 261, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Clonidine; Hydrochlorothiazide; Hypoten

1983
Dizziness in the elderly and calcium channel antagonists.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1991, Volume: 45, Issue:1

    Topics: Aged; Aged, 80 and over; Calcium Channel Blockers; Diuretics; Dizziness; Drug Therapy, Combination;

1991