nicardipine has been researched along with Hypertrophy, Left Ventricular in 6 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
Hypertrophy, Left Ventricular: Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of long-term treatment with sustained-release nicardipine (nicardipine SR) on left ventricular hypertrophy and function were studied." | 7.69 | Effects of long-term treatment with sustained-release nicardipine on left ventricular hypertrophy and function in patients with essential hypertension. ( Hiwada, K; Imamura, Y; Joh, T; Matsubara, W; Ochi, T; Sumimoto, T, 1994) |
| "We investigated the potential role of increased plasma adrenomedullin and brain natriuretic peptide (BNP) levels in a patient with malignant hypertension." | 7.69 | Antihypertensive therapy reduces increased plasma levels of adrenomedullin and brain natriuretic peptide concomitant with regression of left ventricular hypertrophy in a patient with malignant hypertension. ( Ishikawa, K; Kangawa, K; Kawano, Y; Kitamura, K; Matsuo, H; Matsuoka, H; Nishikimi, T; Omae, T; Saito, Y; Yoshihara, F, 1996) |
| "The aim of this study was to compare the effects of a calcium antagonist, nicardipine SR, with an angiotensin-converting enzyme (ACE) inhibitor, alacepril, on the regression of left ventricular hypertrophy (LVH) and function." | 5.08 | Both a calcium antagonist and ACE inhibitor reverse hypertrophy in hypertension but a calcium antagonist also depresses contractility. ( Hiwada, K; Ito, T; Joh, T; Muneta, S; Ochi, T; Sumimoto, T, 1997) |
| " Although the role of antihypertensive therapy in regression of LVH remains controversial, the calcium antagonist nicardipine appears to have an important role to play in the treatment of LVH in hypertension and in congestive heart failure." | 4.78 | Therapeutic advances in the treatment of left ventricular hypertrophy. ( Natsume, T, 1993) |
| "The effects of long-term treatment with sustained-release nicardipine (nicardipine SR) on left ventricular hypertrophy and function were studied." | 3.69 | Effects of long-term treatment with sustained-release nicardipine on left ventricular hypertrophy and function in patients with essential hypertension. ( Hiwada, K; Imamura, Y; Joh, T; Matsubara, W; Ochi, T; Sumimoto, T, 1994) |
| "We investigated the potential role of increased plasma adrenomedullin and brain natriuretic peptide (BNP) levels in a patient with malignant hypertension." | 3.69 | Antihypertensive therapy reduces increased plasma levels of adrenomedullin and brain natriuretic peptide concomitant with regression of left ventricular hypertrophy in a patient with malignant hypertension. ( Ishikawa, K; Kangawa, K; Kawano, Y; Kitamura, K; Matsuo, H; Matsuoka, H; Nishikimi, T; Omae, T; Saito, Y; Yoshihara, F, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kosaka, T | 1 |
| Nakagawa, M | 1 |
| Ishida, M | 1 |
| Iino, K | 1 |
| Watanabe, H | 1 |
| Hasegawa, H | 1 |
| Ito, H | 1 |
| Rakić, D | 1 |
| Rumboldt, Z | 1 |
| Bagatin, J | 1 |
| Polić, S | 1 |
| Sumimoto, T | 2 |
| Hiwada, K | 2 |
| Ochi, T | 2 |
| Matsubara, W | 1 |
| Joh, T | 2 |
| Imamura, Y | 1 |
| Natsume, T | 1 |
| Ito, T | 1 |
| Muneta, S | 1 |
| Nishikimi, T | 1 |
| Matsuoka, H | 1 |
| Ishikawa, K | 1 |
| Yoshihara, F | 1 |
| Kawano, Y | 1 |
| Kitamura, K | 1 |
| Saito, Y | 1 |
| Kangawa, K | 1 |
| Matsuo, H | 1 |
| Omae, T | 1 |
1 review available for nicardipine and Hypertrophy, Left Ventricular
| Article | Year |
|---|---|
Therapeutic advances in the treatment of left ventricular hypertrophy.
Topics: Animals; Antihypertensive Agents; Heart Failure; Hemodynamics; Humans; Hypertension; Hypertrophy, Le | 1993 |
3 trials available for nicardipine and Hypertrophy, Left Ventricular
| Article | Year |
|---|---|
Cardioprotective effect of an L/N-type calcium channel blocker in patients with hypertensive heart disease.
Topics: Adult; Aged; Calcium Channel Blockers; Dihydropyridines; Female; Heart; Humans; Hypertension; Hypert | 2009 |
Effects of four antihypertensive monotherapies on cardiac mass and function in hypertensive patients with left ventricular hypertrophy: randomized prospective study.
Topics: Adult; Aged; Antihypertensive Agents; Chlorthalidone; Croatia; Echocardiography; Female; Heart Ventr | 2002 |
Both a calcium antagonist and ACE inhibitor reverse hypertrophy in hypertension but a calcium antagonist also depresses contractility.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Captopril; Double-B | 1997 |
2 other studies available for nicardipine and Hypertrophy, Left Ventricular
| Article | Year |
|---|---|
Effects of long-term treatment with sustained-release nicardipine on left ventricular hypertrophy and function in patients with essential hypertension.
Topics: Aged; Delayed-Action Preparations; Humans; Hypertension; Hypertrophy, Left Ventricular; Middle Aged; | 1994 |
Antihypertensive therapy reduces increased plasma levels of adrenomedullin and brain natriuretic peptide concomitant with regression of left ventricular hypertrophy in a patient with malignant hypertension.
Topics: Adrenomedullin; Antihypertensive Agents; Atrial Fibrillation; Blood Pressure; Echocardiography; Elec | 1996 |