nicardipine has been researched along with Hypertension in 482 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nicardipine has been shown to lower blood pressure in patients with uncomplicated hypertension as well as in patients with concomitant renal impairment, coronary artery disease or congestive heart failure." | 10.16 | Nicardipine for systemic hypertension: effects on blood pressure and target organ function. ( Ram, CV, 1987) |
| "Fifty-two subjects were prospectively randomized to receive either nicardipine or esmolol as the sole drug for treatment of emergence hypertension at the conclusion of brain tumor resection (40 subjects finally analyzed)." | 9.20 | Nicardipine is superior to esmolol for the management of postcraniotomy emergence hypertension: a randomized open-label study. ( Badri, AM; Bebawy, JF; Carabini, LM; Gupta, DK; Hemmer, LB; Houston, CC; Koht, A; Kosky, JL; Moreland, NC, 2015) |
| "Determine the definitive position of ketanserin and dihydralazine for treatment of severe hypertension in pregnancy." | 9.20 | Ketanserin versus dihydralazine for the treatment of severe hypertension in early-onset preeclampsia: a double blind randomized controlled trial. ( Bijvank, SW; Duvekot, JJ; Edens, MA; Hanff, LM; Roofthooft, DW; Steegers, EA; Visser, W; Vulto, AG, 2015) |
| " Food and Drug Administration (FDA)-recommended doses of labetalol and nicardipine for hypertension (HTN) management in a subset of patients with renal dysfunction (RD)." | 9.19 | The management of acute hypertension in patients with renal dysfunction: labetalol or nicardipine? ( Baumann, BM; Borczuk, P; Cannon, CM; Chandra, A; Cline, DM; Diercks, DB; Hiestand, B; Hsu, A; Jois-Bilowich, P; Kaminski, B; Levy, P; Nowak, RM; Peacock, WF; Schrock, JW; Soto-Ruiz, KM; Varon, J, 2014) |
| "This is a prospective, pseudo-randomized study comparing labetalol and nicardipine for blood pressure (BP) management in acute stroke patients." | 9.17 | A prospective evaluation of labetalol versus nicardipine for blood pressure management in patients with acute stroke. ( Coplin, W; Levy, PD; Liu-DeRyke, X; Parker, D; Rhoney, DH, 2013) |
| "Our study suggests that nicardipine is a more effective antihypertensive agent than labetalol in an unselected group of patients who develop hypertension in the intensive care unit setting." | 9.16 | Intravenous labetalol compared with intravenous nicardipine in the management of hypertension in critically ill patients. ( Hilleman, DE; Malesker, MA, 2012) |
| "The calcium channel blocker nicardipine (NC) is effective for acute control of hypertension." | 9.13 | Prospective randomized comparison of safety and efficacy of nicardipine and nitroprusside drip for control of hypertension in the neurosurgical intensive care unit. ( Alaraj, A; Hardman, J; Mangubat, EZ; Merchant, A; Mlinarevich, N; Roitberg, BZ; Ruland, S; Urbaniak, K; Watson, KS, 2008) |
| "To assess the efficacy and safety of nicardipine in comparison to labetalol in the initial management of severe hypertension in pregnancy." | 9.10 | Short-term treatment of severe hypertension of pregnancy: prospective comparison of nicardipine and labetalol. ( Abroug, F; Boussarssar, M; Elatrous, S; Marghli, S; Nouira, S; Ouanes Besbes, L; Sakkouhi, M, 2002) |
| "A 90-day, multicenter, randomized, double-blind, parallel-group study was conducted to compare the efficacy of amlodipine (once a day) with nicardipine (two to three times a day), in the treatment of isolated systolic hypertension (ISH) in the elderly." | 9.10 | Randomized, comparative, double-blind study of amlodipine vs. nicardipine as a treatment of isolated systolic hypertension in the elderly. ( Bernaud, C; Carre, A; Clerson, P; Emeriau, JP; Jaboureck, O; Mounier-Véhier, C, 2002) |
| "Compare the efficacy of isradipine to that of nicardipine for the control of arterial hypertension following coronary artery bypass graft (CABG)." | 9.10 | [Comparison of nicardipine and isradipine in hypertension following coronary artery bypass graft]. ( Achkouty, R; Antakly, MC; Haddad, F; Hayek, G; Khater-Rassi, D; Madi-Jebara, S; Yazigi, A, 2002) |
| "We compared the efficacy of the combination of enalaprilat/labetalol with that of enalaprilat/nicardipine to prevent emergence postcraniotomy hypertension." | 9.09 | A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery. ( Broad, C; Ferri, E; Kross, RA; Leung, D; Melendez, JA; Pratila, M; Veronesi, M, 2000) |
| "To evaluate the effectiveness of nicardipine and nitroprusside for breakthrough hypertension following carotid endarterectomy." | 9.09 | Nicardipine versus nitroprusside for breakthrough hypertension following carotid endarterectomy. ( Breslow, MJ; Dorman, T; Lipsett, PA; Rosenfeld, BA; Thompson, DA, 2001) |
| "Intravenous nicardipine titration, starting with 10 mg/hr and increased slowly every 4 minutes by the rate 1 mg/hr until target supine DBP of 90 mmHg was achieved, was a very effective and safe method for patients with very severe hypertension." | 9.08 | Intravenous nicardipine for the treatment of severe hypertension. A dose-titration infusion to therapeutic response. ( Sukonthasarn, A, 1995) |
| "This study was a prospective, randomized, double-blind, placebo-controlled clinical trial designed to evaluate the safety and efficacy of oral nicardipine for the treatment of urgent hypertension in the emergency department." | 9.08 | Evaluation of the efficacy and safety of oral nicardipine in treatment of urgent hypertension: a multicenter, randomized, double-blind, parallel, placebo-controlled clinical trial. ( Dunbar, LM; Friday, KJ; Habib, GB; Neale, AC; Rodrigues, R, 1995) |
| "To compare the efficacy of intravenous (iv) nicardipine with nitroglycerin for the treatment for patients with perioperative hypertension." | 9.08 | Comparison of antihypertensive effects of nicardipine with nitroglycerin for perioperative hypertension. ( Chen, TL; Cheng, YJ; Lee, TS; Lin, CJ; Lin, SY; Sun, WZ, 1995) |
| "The primary objective of this study was to compare the antihypertensive efficacy and safety of intravenously administered nicardipine with that of intravenous nitroprusside (SNP) in patients with severe hypertension." | 9.07 | A comparison of intravenous nicardipine and sodium nitroprusside in the immediate treatment of severe hypertension. ( Cook, E; Fletcher, E; Grandy, S; Lee, R; Maher, KE; Neutel, JM; Ram, CV; Smith, DH; Turlepaty, P; Wallin, D, 1994) |
| "To compare the effects of treatment with nicardipine and metoprolol in patients with hypertension during pregnancy." | 9.07 | Nicardipine versus metoprolol in the treatment of hypertension during pregnancy: a randomized comparative trial. ( Carbonne, B; Jannet, D; Milliez, J; Sebban, E, 1994) |
| "We performed a randomized, crossover study comparing the effects of nicardipine and trichlormethiazide on insulin sensitivity in 8 untreated essential hypertensive patients." | 9.07 | Comparison of effects of nicardipine and trichlormethiazide on insulin sensitivity in hypertensive patients. ( Fujita, T; Ishibashi, K; Isogai, Y; Kageyama, S; Mimura, A; Sakurai, T; Yamamoto, J; Yokota, K, 1994) |
| "9 years, suffering from slight or moderate arterial hypertension were treated with either 40 mg of Nicardipine retard twice a day (b." | 9.07 | [Slow-release nicardipine in the treatment of arterial hypertension: comparative study vs. an ACE inhibitor]. ( Adriani, A; Bonfantino, V; De Cesaris, R; Ferrieri, A; Filitti, V; Ranieri, G, 1993) |
| "Sustained-release nicardipine at a dose of 30 to 60 mg every 12 h provided effective and generally well-tolerated antihypertensive control throughout the day in most patients with mild-to-moderate essential hypertension." | 9.07 | Sustained-release nicardipine in mild-to-moderate hypertension. ( Fagan, TC; Kenley, S; Reitman, MA; Tyler, ED; Weber, MA, 1993) |
| "Forty pregnant patients with mild or moderate hypertension received oral nicardipine 20 mg three times a day (mean duration of treatment 9 +/- 2." | 9.07 | Nicardipine treatment of hypertension during pregnancy. ( Carbonne, B; Jannet, D; Khelifati, Y; Milliez, J; Touboul, C, 1993) |
| "The purpose of this placebo-control, double-blind, randomized and crossover study is to evaluate the effect of nicardipine and nifedipine in Chinese senile hypertension." | 9.07 | [Comparison of nicardipine and nifedipine in treatment of Chinese senile hypertension placebo-control, double-blind, randomized and crossover study]. ( Chang, MS; Chen, CH; Chen, JW; Wang, SP, 1992) |
| "The effect of manidipine, a new Ca2+ antagonist, on intrarenal hemodynamics was assessed in essential hypertension and compared with nicardipine, a previously studied Ca2+ antagonist." | 9.07 | Effect of manidipine, a new calcium antagonist, on intrarenal hemodynamics in essential hypertension. ( Abe, H; Ashida, T; Imanishi, M; Kawano, Y; Kimura, G; Kojima, S; Murakami, K; Sanai, T; Yoshida, K; Yoshimi, H, 1992) |
| "A controlled, randomized, single-blind, parallel-group study compared the effects of nicardipine hydrochloride/hydrochlorothiazide (HCTZ) with those of pindolol/HCTZ in treatment of essential hypertension." | 9.07 | A comparative study of nicardipine and pindolol as second-line treatments in essential hypertension. ( Huikko, M; Jounela, A; Kanniainen, E; Penttila, O, 1992) |
| " Hypertension during gastrectomy was treated by increasing the concentration of enflurane, by nicardipine infusion (0." | 9.07 | Treatment of intraoperative hypertension with enflurane, nicardipine, or human atrial natriuretic peptide: haemodynamic and renal effects. ( Goto, F; Kato, S; Sudo, I, 1992) |
| "To compare the efficacy and safety of iv nicardipine with sodium nitroprusside in the treatment of postoperative hypertension after both cardiac and noncardiac surgery." | 9.07 | Postoperative hypertension: a multicenter, prospective, randomized comparison between intravenous nicardipine and sodium nitroprusside. ( Floyd, J; Gabrielson, G; Goldberg, JS; Goldberg, M; Greenstein, RJ; Halpern, NA; Neely, C; Sladen, RN, 1992) |
| "The efficacy and tolerability of nicardipine retard and captopril were assessed in 174 over-60-year-olds suffering from slight or moderate essential hypertension." | 9.07 | [Efficacy and tolerability of nicardipine retard and captopril in hypertension in the aged. Results of a multicenter study]. ( Buoninconti, R; Errico, M; Freda, M; Giordano, MP; Granata, Q; Lucentini, ML; Mancia, G; Marsili, P; Pasotti, C; Piccolo, E, 1992) |
| "In this double-blind, parallel, multicenter study, sustained-release (SR) preparations of 2 calcium antagonists, nicardipine and verapamil, were compared for the treatment of mild to moderate systemic hypertension." | 9.07 | Comparison of sustained-release formulations of nicardipine and verapamil for mild to moderate systemic hypertension. ( Friday, KJ; Frishman, WH; Gradman, AH; Kaihlanen, PM; Wong, SC, 1992) |
| "The effects of a sustained-release formulation of the calcium antagonist nicardipine on left ventricular (LV) mass, Doppler transmitral velocity profiles and plasma neurohumoral studies were analyzed in patients with mild to moderate systemic hypertension." | 9.07 | Effects of sustained-release nicardipine on regression of left ventricular hypertrophy in systemic hypertension. ( Adler, J; Dittrich, HC; Ong, J; Reitman, M; Weber, M; Ziegler, M, 1992) |
| "The extent and duration of the blood pressure (BP) lowering effect of 20 mg nitrendipine (NIT) once daily and 40 mg nicardipine slow release (NIC) twice daily were compared in 12 men (aged 39-55 years) with mild essential hypertension according to a randomized, cross over study." | 9.07 | Nitrendipine 20 mg once daily versus nicardipine slow release 40 mg twice daily in mild essential hypertension: evaluation by 24-hour ambulatory blood pressure monitoring. ( Borgnino, C; Corradi, L; Fogari, R; Malamani, GD; Poletti, L; Tettamanti, F; Zoppi, A, 1992) |
| "In an open, randomized, multicenter trial, intravenous nicardipine was compared with sodium nitroprusside in 74 patients with hypertension (mean arterial pressure [MAP] greater than or equal to 100 mm Hg) following coronary artery bypass surgery." | 9.07 | Comparison of nicardipine and sodium nitroprusside in the treatment of paroxysmal hypertension following aortocoronary bypass surgery. ( David, D; Dubois, C; Loria, Y, 1991) |
| " A novel formulation of nicardipine (25% standard, 75% sustained release--SR) was evaluated in mild hypertension in a double-blind, randomized, placebo-controlled comparison with standard nicardipine (STD), using clinic measurements (Hawksley) augmented by home recorded blood pressures (Copal UA 251)." | 9.07 | Nicardipine sustained release in hypertension. ( Beard, M; Crichton, W; Dow, RJ; Jamieson, M; Jeffers, TA; MacDonald, FC; Petrie, JC; Roy-Chaudhury, P; Webster, J; Witte, K, 1991) |
| "The effects of a calcium-entry blocker, nicardipine, on intrarenal hemodynamics were studied in essential hypertension." | 9.07 | Effect of a calcium-entry blocker, nicardipine, on intrarenal hemodynamics in essential hypertension. ( Abe, H; Ashida, T; Deguchi, F; Imanishi, M; Kawamura, M; Kawano, Y; Kimura, G; Kojima, S; Yoshida, K; Yoshimi, H, 1991) |
| "In a double-blind, randomized, multicenter study, the efficacy and safety of intravenous (IV) nicardipine was compared with placebo in the control of postoperative hypertension in cardiac and noncardiac surgical patients." | 9.07 | Efficacy and safety of intravenous nicardipine in the control of postoperative hypertension. IV Nicardipine Study Group. ( , 1991) |
| "A double-blind, placebo-controlled study was carried out over 120 days to assess the metabolic tolerance and patient acceptability of nicardipine in 20 patients with Type 2 diabetes mellitus and slight hypertension." | 9.06 | The influence of nicardipine in type 2 diabetic patients with slight hypertension. ( Faguer de Moustier, B; Paoli, V, 1990) |
| "Nicardipine, a new dihydropyridine calcium channel blocking agent, has been shown to be effective in the management of hypertension." | 9.06 | Adrenergic response to nicardipine in the management of postoperative hypertension. ( Meacham, PW; Perry, SM; Smith, DW; Wood, M, 1990) |
| "Nicardipine hydrochloride, a new calcium channel blocker for intravenous use, has been compared with placebo in a prospective, randomized, double-blind trial on postoperative hypertension." | 9.06 | Postoperative hypertension: a prospective, placebo-controlled, randomized, double-blind trial, with intravenous nicardipine hydrochloride. ( Alicea, M; Greenstein, R; Halpern, NA; Krakoff, LR, 1990) |
| "The aim of the study was to compare the effect of slow-release (SR) nicardipine, placebo and chlorthalidone on hypertension-related arrhythmias evaluating 24-h ambulatory ECG." | 9.06 | Hypertension and arrhythmias: effects of slow-release nicardipine vs chlorthalidone: a double-blind crossover study. ( Celentano, A; de Divitiis, O; Galderisi, M; Garofalo, M; Mureddu, GF; Tammaro, P, 1990) |
| "The antihypertensive effect of slow-release (SR) nicardipine (40 mg twice a day) and chlorthalidone (25 mg once a day), was evaluated in 36 patients with mild to moderate hypertension by casual and 24-h BP monitoring." | 9.06 | Effects on casual and 24-h ambulatory blood pressure of slow-release nicardipine and chlorthalidone in arterial essential hypertension: double-blind, crossover study. ( Celentano, A; de Divitiis, O; Galderisi, M; Garofalo, M; Mureddu, GF; Tammaro, P, 1990) |
| "Nicardipine hydrochloride, a dihydropyridine calcium entry-blocking drug, was administered to 66 patients with severe hypertension during three protocols designed to examine the efficacy and safety of this investigation drug." | 9.06 | Intravenous nicardipine hydrochloride: treatment of patients with severe hypertension. ( Wallin, JD, 1990) |
| ") nicardipine hydrochloride (a calcium antagonist) compared with nitroglycerin, the drug generally used for treatment of hypertension after coronary artery bypass grafting, was tested in 20 postoperative patients." | 9.06 | Comparison of intravenous nicardipine and nitroglycerin to control systemic hypertension after coronary artery bypass grafting. ( Gibson, DG; Lennox, SC; Nicolaides, EP; Swanson, KT; Vecht, RJ, 1989) |
| "The purpose of the study was to evaluate the effects of a dihydropyridine calcium antagonist, nicardipine (N), on blood pressure (BP) and aldosterone secretion in hypertensive patients (pt) with primary aldosteronism." | 9.06 | [Effect of a calcium inhibitor, nicardipine, on aldosterone secretion in primary hyperaldosteronism]. ( Begasse, F; Chamontin, B; David, D; Salvador, M, 1989) |
| "The antihypertensive effect of nicardipine was evaluated in 89 ambulatory elderly patients with hypertension through a multicenter trial enrolling patients over the age of 65 years." | 9.06 | Nicardipine monotherapy in ambulatory elderly patients with hypertension. ( Krakoff, LR, 1989) |
| " We evaluated the relative efficacies and tolerability of various low-dose combinations of nicardipine and propranolol in patients with mild-moderate essential hypertension (DBP Phase V of greater than 90-125 mmHg; WHO Grades I and II) in order to select the best one." | 9.06 | Comparison of the efficacy and acceptability of nicardipine and propranolol, alone and in combination, in mild to moderate hypertension. ( Dow, RJ; Gough, KJ; Laing, EM; Macdonald, FC; Maclean, D; McDevitt, DG; Mitchell, ET, 1989) |
| "Sixty-six patients with severe hypertension were treated with intravenous nicardipine in 3 separate protocols." | 9.06 | Intravenous nicardipine in severe systemic hypertension. ( Bienvenu, GS; Clifton, GG; Cook, ME; Wallin, JD, 1989) |
| "A placebo-controlled, double-blind multicenter trial was conducted in 123 patients with severe hypertension to examine the efficacy and safety of intravenously administered nicardipine hydrochloride in controlling blood pressure." | 9.06 | Intravenous nicardipine for the treatment of severe hypertension. A double-blind, placebo-controlled multicenter trial. ( Cheung, DG; Cook, ME; Davis, WR; Fletcher, E; Langford, HG; MacCarthy, EP; Ram, CV; Saunders, E; Townsend, R; Wallin, JD, 1989) |
| " A novel formulation of nicardipine (50% standard (short acting), 50% sustained release) was evaluated in mild hypertension in a double-blind, randomized, placebo-controlled study, using clinic measurements (Hawksley) augmented by home recorded blood pressures (Copal UA 251)." | 9.06 | Evaluation of a long acting formulation of nicardipine in hypertension by clinic and home recorded blood pressures and Doppler aortovelography. ( Jeffers, TA; Petrie, JC; Rawles, J; Webster, J; Witte, K, 1989) |
| "The effect of adding placebo, a calcium antagonist, nicardipine and a thiazide diuretic, chlorthalidone, each for 2 weeks, to ongoing treatment with the ACE inhibitor, enalapril was evaluated in seven patients with essential hypertension." | 9.06 | Enalapril in essential hypertension: the comparative effects of additional placebo, nicardipine and chlorthalidone. ( Donnelly, R; Elliott, HL; Meredith, PA; Reid, JL, 1987) |
| "The two dihydropyridine calcium antagonists, nicardipine and nifedipine, were compared in 12 patients with both stable angina pectoris and systemic hypertension using a double-blind, crossover protocol." | 9.06 | A randomized double-blind crossover study of nicardipine and nifedipine in patients with angina pectoris and concomitant essential hypertension. ( Bonandi, L; Dei Cas, L; Feroldi, P; Metra, M; Nodari, S; Nordio, G; Raddino, R; Visioli, O, 1988) |
| "Thirty patients with mild to moderate essential hypertension entered a randomised double-blind parallel group study for 6 months to compare the effects of the new calcium channel blocker nicardipine 90 mg/day and propranolol 240 mg/day." | 9.06 | Nicardipine in the treatment of essential hypertension controlled 6-month-study comparing nicardipine with propranolol at rest and during exercise. ( Bjerle, P; Danielsson, A; Ek, B; Steen, L; Suhr, O, 1987) |
| "In a double-blind controlled trial 22 patients with mild or moderate essential hypertension were treated with nicardipine 30 mg t." | 9.06 | Comparison of nicardipine and propranolol in the treatment of mild and moderate hypertension. ( Karppinen, K; Naukkarinen, VA; Sarna, S, 1987) |
| "Thirty-nine patients with mild to moderate essential hypertension participated in a parallel, single-blind study comparing 6 weeks' treatment of nicardipine hydrochloride (90 mg/day) with nifedipine (40 mg/day)." | 9.06 | Comparison of the efficacy of nicardipine, a new calcium channel blocker, with nifedipine in the treatment of mild to moderate essential hypertension. ( Armstrong, C; Blackwood, R; Garnham, J, 1987) |
| "The antihypertensive effect of twice-daily nicardipine, an investigational calcium-channel blocker, was evaluated in a placebo-controlled, single-blind trial in 18 adult patients with essential hypertension (supine diastolic blood pressure [BP] of greater than or equal to 95 and less than or equal to 120 mmHg)." | 9.06 | Twice-daily nicardipine in the treatment of essential hypertension. ( Charlap, S; Dorsa, F; Kafka, K; Kimmel, B; Laifer, L; Lazar, E; Saltzberg, S; Singer, M; Strom, J; Weinberg, P, 1986) |
| "A twelve-week parallel study was conducted to compare the efficacy and safety of nicardipine plus propranolol with that of propranolol alone in 67 patients with mild to moderate essential hypertension." | 9.06 | Comparison of concomitant nicardipine hydrochloride and propranolol with propranolol alone in patients with essential hypertension. ( Douglas-Jones, AP; Havard, CW; Nievel, JG, 1987) |
| "We studied the renal effects of nicardipine, a calcium entry blocker, in seven patients with mild-to-moderate essential hypertension." | 9.06 | Renal effects of nicardipine in patients with mild-to-moderate essential hypertension. ( Baba, T; Boku, A; Ishizaki, T; Sone, K; Takebe, K, 1986) |
| "A systematic review of published manuscripts was performed to identify studies of patients who received sodium nitroprusside and nicardipine as part of the treatment for arterial hypertension or afterload reduction after cardiac surgery." | 9.05 | Sodium nitroprusside versus nicardipine for hypertension management after surgery: A systematic review and meta-analysis. ( Bronicki, RA; Flores, S; Iranpour, N; Kriz, C; Loomba, RS; Villarreal, EG, 2020) |
| "Fifty patients with mild essential (primary) hypertension entered a double-blind, parallel-group study with either nicardipine 30 mg three times daily or placebo, randomly assigned as monotherapy for 6 weeks." | 9.05 | Nicardipine hydrochloride in essential hypertension--a controlled study. ( Asplund, J, 1985) |
| "The dose-response effects of oral nicardipine on the systemic blood pressure were examined in 54 patients with uncomplicated essential hypertension (DBP greater than or equal to 100 mm Hg)." | 9.05 | Anti-hypertensive dose-response effects of nicardipine in stable essential hypertension. ( Frais, MA; Jackson, N; Lee, P; Silke, B; Taylor, SH; Verma, SP, 1985) |
| " Therefore, we analyzed the potency and side effects of two treatment options (nicardipine compared to labetalol) in order to gain insight in improved treatment of severe hypertension during pregnancy and to evaluate the feasibility of a randomised controlled trial." | 8.90 | The optimal treatment of severe hypertension in pregnancy: update of the role of nicardipine. ( de Groot, CJ; Meuleman, T; Nooij, LS; Roelofs, R; Visser, S; Vos, P, 2014) |
| "Nicardipine is an antagonist of calcium influx through the slow channel of the cell membrane and has been shown to be an effective and relatively well-tolerated treatment for stable effort angina and rest angina due to coronary artery spasm, and mild to moderate hypertension." | 8.77 | Nicardipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in the treatment of angina pectoris, hypertension and related cardiovascular disorders. ( Clissold, SP; Sorkin, EM, 1987) |
| "In patients with hemorrhagic stroke, nicardipine appeared to have similar efficacy as clevidipine in SBP reduction, with a more likely reduction of rebound hypertension and drug cost." | 8.12 | Comparison of Clevidipine and Nicardipine for Acute Blood Pressure Reduction in Hemorrhagic Stroke. ( Breslin, J; Hanify, J; Heierman, T; Larizadeh, K; Phipps, W; Saldana, S; Sanchez, M, 2022) |
| "This multicenter, retrospective case series included all pregnant women beyond 20 weeks of gestation with severe antepartum hypertension that were treated with intravenous nicardipine." | 8.12 | Nicardipine for treating severe antepartum hypertension during pregnancy: Nine years of experience in more than 800 women. ( Cornette, JC; Duvekot, JJ; Edens, MA; Hengst, M; Huigen, S; Nij Bijvank, SW; Winkelen, AV, 2022) |
| "Nicardipine is an antihypertensive drug that may be used off-label by oral route to treat hypertension in children." | 8.02 | Stability study of a compounded oral solution of nicardipine for the treatment of hypertension in children. ( Buchbinder, N; Colnot, M; Coquard, A; Fuss, D; Gondé, H; Hervouët, C; Lamoureux, F; Pereira, T; Varin, R, 2021) |
| "The aim of this study was to compare radial arterial catheter-derived pressure with oscillometric blood pressure in women with severe peripartum hypertension undergoing urgent treatment with intravenous nicardipine at a maternal intensive care unit." | 8.02 | Intra-arterial versus oscillometric blood pressure measurements in women with severe peripartum hypertension undergoing urgent treatment with nicardipine: An observational study. ( Gan, S; Lan, L; Li, L; Qi, H; Qin, J; Ren, L; Xiang, B; Yan, Y; Zhang, Y, 2021) |
| "To assess the safety and efficacy of continuous infusion (CIV)-labetalol compared to -nicardipine in controlling blood pressure (BP) in the acute stroke setting." | 8.02 | Blood Pressure Control in Acute Stroke: Labetalol or Nicardipine? ( El-Ghoroury, H; Hecht, JP; Sudekum, DM, 2021) |
| "To investigate the efficacy of low-dose intravenous nicardipine for emergent management of severe postpartum hypertension in maternal intensive care units (ICUs)." | 7.96 | Efficacy of low-dose nicardipine for emergent treatment of severe postpartum hypertension in maternal intensive care units: An observational study. ( Gan, S; Lan, L; Li, L; Qi, H; Qin, J; Ren, L; Yan, Y; Zhang, Y, 2020) |
| " Nicardipine and labetalol are commonly administered for the treatment of acute hypertension following stroke." | 7.91 | Nicardipine Associated Risk of Short-Term Mortality in Critically Ill Patients with Ischemic Stroke. ( Desai, A; Hanni, C; Mohamed, W; Parker, D; Saber, H; Sadeghi, M; Singh, A, 2019) |
| "Labetalol and nicardipine are antihypertensives commonly used in the management of elevated blood pressure (BP) following an acute stroke, but there is limited evidence to suggest which agent as a continuous infusion should be used preferentially in this setting." | 7.88 | Continuous-Infusion Labetalol vs Nicardipine for Hypertension Management in Stroke Patients. ( Hecht, JP; Richards, PG, 2018) |
| "Nicardipine is frequently used in the treatment of hypertension for patients with acute stroke; however, its dosing is complicated by a high risk of phlebitis." | 7.88 | Reduction of Nicardipine-Related Phlebitis in Patients with Acute Stroke by Diluting Its Concentration. ( Kawada, K; Miyamoto, N; Ohta, T; Tanaka, K, 2018) |
| "This retrospective review compared nicardipine with clevidipine for hypertension in acute stroke patients from March 17, 2015 to December 23, 2016." | 7.88 | Comparison of Nicardipine with Clevidipine in the Management of Hypertension in Acute Cerebrovascular Diseases. ( Conklen, K; Deshpande, M; Ferrill, D; Jones, B; Rosenfeldt, Z; Siddiqui, FM, 2018) |
| "Nicardipine is a dihydropyridine calcium-channel blocker that is frequently used in the acute treatment of hypertension in the emergency department (ED)." | 7.83 | Bradycardia caused by intravenous nicardipine in an elderly patient with acute ischemic infarct. ( Abboud, ME; Frasure, SE, 2016) |
| "We performed a retrospective review of children recovering from aortic coarctectomy or superior cavopulmonary anastomoses who received nicardipine for hypertension at our institution between 2007 and 2013." | 7.83 | Nicardipine for Hypertension Following Aortic Coarctectomy or Superior Cavopulmonary Anastomosis. ( Arango Uribe, D; Mastropietro, CW, 2016) |
| "Intravenous nicardipine is generally used to treat hypertension in acute stroke patients but is associated with frequent phlebitis." | 7.83 | Risk Factors of Nicardipine-Related Phlebitis in Acute Stroke Patients. ( Kadoguchi, N; Kawada, K; Morimoto, M; Ohta, T; Tanaka, K; Yamamoto, S, 2016) |
| "This study aimed to compare the effects of labetalol, nicardipine, or hydralazine on time to target blood pressure before alteplase administration in patients with acute ischemic stroke." | 7.81 | Time to Blood Pressure Control Before Thrombolytic Therapy in Patients With Acute Ischemic Stroke: Comparison of Labetalol, Nicardipine, and Hydralazine. ( Cortes, J; Hall, AB; McKay, C, 2015) |
| "Nicardipine and labetalol are two commonly used antihypertensives for treating elevated blood pressures in the setting of intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH)." | 7.79 | Effectiveness and safety of nicardipine and labetalol infusion for blood pressure management in patients with intracerebral and subarachnoid hemorrhage. ( Agarwal, S; Badjatia, N; Carpenter, AM; Claassen, J; Lantigua, H; Lee, K; Lesch, C; Li, M; Mayer, SA; Ortega-Gutierrez, S; Reccius, A; Schmidt, JM; Thomas, J, 2013) |
| "American Heart Association/American Stroke Association guidelines for management of aneurysmal subarachnoid hemorrhage (aSAH) recommend blood pressure (BP) control, utilizing labetalol or nicardipine, but do not differentiate efficacy between the two agents." | 7.78 | Retrospective evaluation of nicardipine versus labetalol for blood pressure control in aneurysmal subarachnoid hemorrhage. ( Barletta, JF; DeShane, RS; Figueroa, BE; McAllen, KJ; Woloszyn, AV, 2012) |
| "Evaluate the ease of use and tolerability of labetalol (L) and nicardipine (N) for hypertension management in patients with acute stroke." | 7.74 | A comparison of nicardipine and labetalol for acute hypertension management following stroke. ( Coplin, WM; Janisse, J; Liu-Deryke, X; Norris, G; Parker, D; Rhoney, DH, 2008) |
| "To describe the clinical course of a newborn (gestational age 38 wk, 6 d) administered intravenous nicardipine to control hypertension while on extracorporeal membrane oxygen (ECMO) support." | 7.72 | Nicardipine to control neonatal hypertension during extracorporeal membrane oxygen support. ( Campbell, M; Frey, BM; McBride, BF; White, CM, 2003) |
| "To examine the effect of intravenous nicardipine in the treatment of children with severe hypertension." | 7.71 | Intravenous nicardipine for treatment of severe hypertension in children. ( Brophy, PD; Bunchman, TE; Flynn, JT; Kershaw, DB; Mottes, TA; Smoyer, WE, 2001) |
| "In the present study, in order to elucidate the role of dihydropyridine (DHP)-sensitive calcium (Ca) channels in the regulation of neurotransmitter release in hypertension, we examined the effects of the DHP-sensitive Ca channel blocker nicardipine on norepinephrine (NE) release in blood vessels of spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto (WKY) rats." | 7.71 | Role of dihydropyridine-sensitive calcium channels in the regulation of norepinephrine release in hypertension. ( Masuyama, Y; Nishio, I; Tsuda, K; Tsuda, S, 2001) |
| "Nicardipine, a dihydropyridine type calcium channel blocker, was infused at two flow-rates into spontaneously hypertensive (SH) and control normotensive Wistar-Kyoto (WKY) rats (young, 6-week-old and adult, 23-week-old, n = 5) under pentobarbital anesthesia, to cause hypotension." | 7.70 | Changes of plasma L-arginine levels in spontaneously hypertensive rats under induced hypotension. ( Fukushima, T; Homma, H; Imai, K; Kasai, C; Matsunaga, H; Mori, T; Prados, P; Santa, T, 1999) |
| "Isradipine is an effective, orally administered agent for control of hypertension in children." | 7.70 | Initial experience with isradipine for the treatment of hypertension in children. ( Groshong, T; Strauser, LM; Tobias, JD, 2000) |
| " Among these agents, diltiazem has been found to be sufficiently potent to control systemic hypertension but to have a less potent dilatory action on the cerebral vasculature in experimental animals." | 7.69 | Control of systemic hypertension with diltiazem, a calcium-antagonist, in patients with a mildly elevated intracranial pressure: a comparative study. ( Hirayama, T; Kano, T; Katayama, Y; Tsubokawa, T, 1994) |
| "The effects of long-term treatment with sustained-release nicardipine (nicardipine SR) on left ventricular hypertrophy and function were studied." | 7.69 | Effects of long-term treatment with sustained-release nicardipine on left ventricular hypertrophy and function in patients with essential hypertension. ( Hiwada, K; Imamura, Y; Joh, T; Matsubara, W; Ochi, T; Sumimoto, T, 1994) |
| "This trial was designed to confirm the hypotensive action and safety of slow-release nicardipine, as a single drug or together with other hypotensive drugs, for the short-term treatment of mild-to-moderate hypertension, on a large case list of patients in 57 centers throughout Italy." | 7.69 | [Nationwide drug surveillance project on slow-release nicardipine in the short-term therapy of light/moderate arterial hypertension]. ( Benvenuti, C; Guerini Rocco, C; Trezzi, P, 1995) |
| "This study confirms the excellent efficacy of nicardipine in the management of postoperative hypertension, but underlines the risk of poor cardiac tolerance in patients after major surgery." | 7.69 | Intravenous nicardipine in the treatment of postoperative arterial hypertension. ( Berlot, G; Dereume, JP; Engelman, E; Khan, RJ; Preiser, JC; Vincent, JL, 1997) |
| "Seven patients scheduled for clipping of an aneurysm of the internal carotid artery after subarachnoid haemorrhage, were studied in order to evaluate the efficacy of a bolus injection of nicardipine (2 mg) in the treatment of intra-operative hypertension on the blood flow velocity of vessel near the aneurysm under isoflurane anaesthesia." | 7.68 | Effect of nicardipine on the blood flow velocity in the vessel near a cerebral aneurysm of the internal carotid artery during cerebral aneurysm surgery: its therapeutic use for intra-operative hypertension. ( Abe, K; Inagaki, Y; Iwanaga, H, 1993) |
| "Effects of Ca ion channel blockers, nicardipine, diltiazem and nifedipine on intraoperative hypertension were evaluated clinically in ninety surgical patients who received various surgical procedures under total intravenous anesthesia with droperidol, fentanyl and ketamine." | 7.68 | [Clinical study of total intravenous anesthesia with droperidol, fentanyl and ketamine--effects of nicardipine, diltiazem and nifedipine on intraoperative hypertension]. ( Hashimoto, Y; Hirota, K; Ishihara, H; Koh, H; Matsuki, A; Takagi, H, 1993) |
| "The present study was designed to investigate the effect of nicardipine administration upon systolic blood pressure (SBP) and cardiac hypertrophy in spontaneously hypertensive rats (SHR)." | 7.68 | Effect of nicardipine treatment upon cardiac hypertrophy in spontaneously hypertensive rats: a morphometric and ultrastructural study. ( Amenta, F; Bronzetti, E; Ciriaco, E; Felici, L; Ferrante, F, 1992) |
| "The effects of the calcium antagonist nicardipine on the pressor response to mental arithmetic, cold pressor and exercise tests have been studied in fifteen patients with established mild to moderate essential hypertension." | 7.68 | Effect of nicardipine on haemodynamic response to stress in hypertension. ( Hashimoto, N; Kobayashi, K; Nakamura, S; Satoh, S; Takabatake, T; Yamada, Y; Yamamoto, Y, 1992) |
| "Intraoperative hypertension over 160 mmHg systolic observed during total intravenous anesthesia with droperidol, fentanyl and ketamine was treated with intravenous nicardipine in 50 surgical patients." | 7.68 | [Clinical study on total intravenous anesthesia with droperidol, fentanyl and ketamine--4. Control of intraoperative hypertension with nicardipine]. ( Amano, N; Hirota, K; Ishihara, H; Koh, H; Kotani, N; Matsuki, A, 1991) |
| "Fifty-six patients with severe hypertension were treated with intravenous nicardipine for infusion periods of eight to twenty-four hours." | 7.68 | Intravenous nicardipine: an effective new agent for the treatment of severe hypertension. ( Clifton, GG; Wallin, JD, 1990) |
| "Fourteen patients with vascular disease were studied to evaluate the efficacy of nicardipine hydrochloride as a hypotensive agent in the treatment of acute hypertension occurring during anaesthesia." | 7.67 | Haemodynamic effects of nicardipine hydrochloride. Studies during its use to control acute hypertension in anaesthetized patients. ( Furuya, H; Kishi, Y; Okumura, F, 1984) |
| "The effects of the calcium-entry blocker nicardipine on brachial hemodynamics were studied in 22 patients (18 male, 4 female) with essential hypertension, who were treated with 20 mg tid for 1 year." | 7.67 | Effects of long-term nicardipine treatment on hemodynamics of large arteries in essential hypertension. ( Arcaro, G; Arosio, E; Lechi, A; Montesi, G; Pancera, P; Priante, F; Zannoni, M, 1989) |
| "The efficacy of nicardipine and nitroprusside in preventing poststernotomy hypertension was compared in two groups of 45 patients undergoing coronary artery surgery." | 7.67 | The efficacy of nicardipine and nitroprusside in preventing poststernotomy hypertension. ( Deen, L; Dijkhuis, JP; Koolen, JJ; Leyssius, AT; Meyne, NG; van Wezel, HB; Vergroesen, I; Visser, CA, 1989) |
| "Acute effects of coronary vasodilators (nifedipine, nicardipine, and nitroglycerin) on atrial natriuretic peptide (ANP) and the renin-angiotensin-aldosterone system were studied in normal subjects and patients with essential hypertension." | 7.67 | Effects of calcium antagonists and nitroglycerin on atrial natriuretic peptide in normal subjects and patients with essential hypertension. ( Aizawa, T; Ishihara, M; Iwasaki, T; Niwa, A; Shinoda, T; Yamada, T, 1989) |
| "Eighteen patients with severe hypertension received treatment with intravenous nicardipine." | 7.67 | Intravenous nicardipine for the treatment of severe hypertension. ( Bienvenu, GS; Blanski, L; Clifton, GG; Cook, ME; Laddu, A; Langford, H; Turlapaty, P; Wallin, JD, 1988) |
| "We evaluated the immediate hemodynamic response to nicardipine, administered as an intravenous bolus and 30-minute sustaining infusion, in 10 patients with systemic hypertension (HTN) and 10 patients with chronic congestive heart failure (CHF)." | 7.67 | Influence of baseline hemodynamic status and sympathetic activity on the response to nicardipine, a new dihydropyridine, in patients with hypertension or chronic congestive heart failure. ( Cody, RJ; Kubo, SH; Ryman, KS; Shaknovich, A, 1987) |
| "In 10 patients with moderate to severe hypertension, the hemodynamic effects of ergometric exercise and nicardipine, a dihydropyridine calcium channel antagonist, were characterized under basal conditions and after 1 week of therapy." | 7.67 | Systemic and pulmonary hemodynamic responses to nicardipine during graded ergometric exercise in patients with moderate to severe essential hypertension. ( Cody, RJ; Kubo, SH; Laragh, JH; Ryman, KS; Shaknovich, A, 1987) |
| "Clevidipine is a novel, rapidly acting dihydropyridine L-type calcium channel blocker with an ultrashort half-life that decreases arterial blood pressure (BP)." | 6.73 | The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients. ( Aronson, S; Cheung, AT; Dyke, CM; Kereiakes, DJ; Levy, JH; Lumb, PD; Newman, MF; Stierer, KA, 2008) |
| "Renal hemodynamics was investigated in 25 patients." | 6.68 | Effects of benazepril and nicardipine on microalbuminuria in normotensive and hypertensive patients with diabetes. ( Andriani, A; Bertocchi, F; Bonfantino, MV; Cavallo, A; De Cesaris, R; Lamontanara, G; Ranieri, G, 1996) |
| "Hypertension is often related to metabolic disorders, such as android obesity, glucose intolerance, dyslipidemia, and hyperinsulinism (X syndrome)." | 6.67 | Comparison of the effects of captopril and nicardipine on insulin sensitivity and thrombotic profile in patients with hypertension and android obesity. CaptISM Study Group. Captopril Insulin Sensitivity Multicenter Study Group. ( Boucher, L; Cozic, JA; Gorlier, R; Huin, P; Pettenuzzo-Mollo, M; Provendier, O; Raccah, D; Sicard, J; Vague, P, 1994) |
| "Hypertension was significantly better controlled in patients treated with nicardipine infusion compared with placebo (83% vs." | 6.67 | Nicardipine infusion for postoperative hypertension after surgery of the head and neck. ( Alicea, M; Goldberg, JS; Greenstein, R; Halpern, NA; Krakoff, LR; Neely, C; Sladen, RN; Wood, M, 1990) |
| "Nicardipine (80 mg/day) was given orally for 12 weeks and no dietary restrictions were imposed." | 6.67 | Efficacy of nicardipine slow release (SR) on hypertension, potassium balance and plasma aldosterone in idiopathic aldosteronism. ( Bisbocci, D; Chiandussi, L; Pinna, G; Piras, D; Rabbia, F; Veglio, F, 1990) |
| " The usefulness of intravenous nicardipine for postoperative hypertension was demonstrated in this study by: (1) the rapid control of blood pressure, (2) its continued efficacy during maintenance, and (3) little need to adjust dosage to control blood pressure." | 6.67 | Nicardipine versus placebo for the treatment of postoperative hypertension. ( Clark, S; Goldberg, ME; Joseph, J; Maguire, D; Moritz, H; Seltzer, JL; Turlapaty, P, 1990) |
| "Both drugs were effective in the treatment of hypertension." | 6.67 | Nicardipine and propranolol in the treatment of hypertension: similar antihypertensive but dissimilar hemodynamic actions. ( Featherston, W; Gonzalez, DG; Kaplan, NM; Lugo, C; Ralakis, J; Ram, CV, 1990) |
| " Two weeks of combined treatment with nicardipine and enalapril significantly reduced the predosing blood pressure, 12 h after the last dose of nicardipine (158/96 as compared with 172/106 with placebo), and there were further significant reductions in blood pressure during the subsequent dosage interval." | 6.66 | An evaluation of the pharmacodynamics and pharmacokinetics of nicardipine combined with enalapril in essential hypertension. ( Donnelly, R; Elliott, HL; Meredith, PA; Reid, JL, 1987) |
| "Nicardipine was well tolerated; orthostatic hypotension was not observed and there was no change in heart rate." | 6.66 | Nicardipine in elderly patients with hypertension: a review of experience in France. ( Bouchacourt, P; Forette, F; Henry, JF; Hervy, MP; McClaran, J, 1989) |
| "Nicardipine is an investigational dihydropyridine calcium channel blocking agent." | 6.66 | Nicardipine and hydrochlorothiazide in essential hypertension. ( Brown, R; Conrad, KA; Fagan, TC; Freedman, D; Lessem, J; Michelson, E; Montijo, M; Schnaper, H; Smolens, P, 1989) |
| "Treatment with amiloride + HCTZ led to elevations in serum levels of cholesterol, uric acid and urea, which were maintained at one year, whilst no abnormalities in blood biochemistry were seen in patients treated with nicardipine." | 6.66 | A randomised comparative trial of nicardipine versus amiloride and hydrochlorothiazide in mild to moderate hypertension. A report from the General Practitioner Hypertension Study Group. ( Bradley, I; Davis, A; Ganvir, P; Gostick, NK; Hopwood, AM; MacKay, D; Mayhew, SR; Mukerji, D; Shepherd, F, 1989) |
| "Nicardipine-based treatment reduced systolic and diastolic blood pressures to similar levels independently of the age of the patients." | 6.66 | Antihypertensive efficacy of nicardipine-based treatment in patients of different age and in patients with isolated systolic hypertension. ( Leonetti, G; Zanchetti, A, 1988) |
| "Nicardipine appears to blunt the secretion of aldosterone responding to an increased PRA possibly through its calcium-antagonizing action." | 6.66 | Multiple oral doses of nicardipine, a calcium-entry blocker: effects on renal function, plasma renin activity, and aldosterone concentration in mild-to-moderate essential hypertension. ( Aoyagi, K; Baba, T; Ishizaki, T; Murabayashi, S; Takebe, K; Tamasawa, N, 1987) |
| "We conducted a randomized placebo-controlled double-blind study in 40 hypertensive subjects to assess the antihypertensive effect of a new galenic form of nicardipine administered at a dosage of 50 mg twice daily for 3 weeks." | 6.66 | Evaluation of slow release nicardipine in essential hypertension by casual and ambulatory blood pressure measurements. Effects of acute versus chronic administration. ( Bellet, M; Chatellier, G; Corvol, P; Ménard, J; Pagny, JY, 1987) |
| "Nicardipine was given three times a day (mean dose: 69." | 6.65 | [Treatment of arterial hypertension in the aged with a calcium antagonist: nicardipine]. ( Bellet, M; Bouchacourt, P; Forette, F; Henry, JF; Hervy, MP; Poyard-Salmeron, C, 1984) |
| "Nicardipine is a water soluble calcium channel antagonist, with predominantly vasodilatory actions." | 6.43 | Intravenous nicardipine: its use in the short-term treatment of hypertension and various other indications. ( Curran, MP; Keating, GM; Robinson, DM, 2006) |
| "Nicardipine is a second generation dihydropyridine-type Ca2+ antagonist with high vascular selectivity and strong cerebral and coronary vasodilatory activity." | 6.39 | Nicardipine and treatment of cerebrovascular diseases with particular reference to hypertension-related disorders. ( Amenta, F; Sabbatini, M; Strocchi, P, 1995) |
| "Nicardipine has a short duration factor, is easily titratable and is as effective as nitroglycerin or nitroprusside in the control of hypertension." | 6.38 | Clinical considerations for the use of intravenous nicardipine in the treatment of postoperative hypertension. ( Kaplan, JA, 1990) |
| "Nicardipine has been shown to lower blood pressure in patients with uncomplicated hypertension as well as in patients with concomitant renal impairment, coronary artery disease or congestive heart failure." | 6.16 | Nicardipine for systemic hypertension: effects on blood pressure and target organ function. ( Ram, CV, 1987) |
| "Perioperative hypertension is a common occurrence in the neurosurgical population, where 60% to 90% of the patients require treatment for blood pressure (BP) control." | 5.56 | Clevidipine use after first-line treatment failure for perioperative hypertension in neurosurgical patients: A single-center experience. ( Bergese, SD; Borrell-Vega, J; Palettas, M; Uribe, AA, 2020) |
| "A history of hypertension is a known risk factor for delirium in patients in intensive care units, but the effect of antihypertensive agents on delirium development is unclear." | 5.48 | Relationship between the administration of nicardipine hydrochloride and the development of delirium in patients on mechanical ventilation. ( Chuma, M; Goda, M; Hamano, H; Horinouchi, Y; Imai, T; Imanishi, M; Ishizawa, K; Kayano, M; Kitamura, Y; Kondo, Y; Kouno, Y; Koyama, T; Mitsui, M; Niimura, T; Okada, N; Sendo, T; Takechi, K; Ujike, Y; Yanagawa, H; Zamami, Y, 2018) |
| " Controlling acute hypertension (HTN) by antihypertensive drugs such as clevidipine and nicardipine can be a highly efficient method of lowering the incidence of CVDs." | 5.41 | Comparison between clevidipine and nicardipine in cerebrovascular diseases: A systematic review and meta-analysis. ( Asgarzadeh, S; Azari Jafari, A; Azari Jafari, M; Godoy, DA; Mirmoeeni, S; Nazari, S; Seifi, A; Shah, M, 2023) |
| "CIVN, used to treat post-KTX hypertension, may inhibit TAC metabolism resulting in overexposure and potential toxicity." | 5.37 | Interaction between tacrolimus and intravenous nicardipine in the treatment of post-kidney transplant hypertension at pediatric hospitals. ( Carle, AC; Goebel, J; Hooper, DK; Schuchter, J, 2011) |
| "Clevidipine is an arterial, selective, dihydropyridine calcium channel blocker with an ultrashort half-life." | 5.35 | Clevidipine in the treatment of perioperative hypertension: assessing safety events in the ECLIPSE trials. ( Aronson, S, 2009) |
| "Treatment with nicardipine countered microanatomical changes occurring in SHR, whereas hydralazine displayed a less pronounced effect." | 5.32 | Treatment with nicardipine protects brain in an animal model of hypertension-induced damage. ( Amenta, F; Tomassoni, D, 2004) |
| "Nicardipine was well tolerated and induced a significant decrease (p < 0." | 5.29 | Effect of nicardipine treatment on carbohydrate and lipoprotein metabolism in patients with hypertension. ( Chen, LM; Chu, NF; Fuh, MM; Shen, DC; Sheu, WH; Wang, DJ, 1993) |
| "Nicardipine is an investigational dihydropyridine calcium-channel blocker." | 5.28 | Nicardipine in severe hypertension: oral therapy following intravenous treatment. ( Bienvenu, GS; Clifton, GG; Cook, E; Laddu, A; Turlapaty, P; Wallin, JD, 1990) |
| "The degree of cerebral ischemia 4 hr after BLCL was estimated by the levels of brain energy metabolites (ATP, lactate, c-AMP) and brain water content." | 5.27 | [Influence of long-term antihypertensive treatment on cerebral ischemia induced by bilateral common carotid artery ligation in SHRSR--protective effect of nicardipine hydrochloride]. ( Katayama, Y; Memezawa, H; Nagazumi, A; Sugimoto, S; Suzuki, S; Terashi, A, 1987) |
| " Randomized controlled trials or comparative observational studies that evaluated clevidipine, nicardipine, labetalol, esmolol, or nitroprusside for acute neurologic emergencies were included." | 5.22 | Comparison of Intravenous Antihypertensives on Blood Pressure Control in Acute Neurovascular Emergencies: A Systematic Review. ( Brown, CS; Cabrera, D; Farrell, K; Gerberi, DJ; Mattson, AE; Oliveira J E Silva, L; Rabinstein, AA, 2022) |
| "We randomly assigned eligible participants with intracerebral hemorrhage (volume, <60 cm(3)) and a Glasgow Coma Scale (GCS) score of 5 or more (on a scale from 3 to 15, with lower scores indicating worse condition) to a systolic blood-pressure target of 110 to 139 mm Hg (intensive treatment) or a target of 140 to 179 mm Hg (standard treatment) in order to test the superiority of intensive reduction of systolic blood pressure to standard reduction; intravenous nicardipine to lower blood pressure was administered within 4." | 5.22 | Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage. ( Barsan, WG; Hanley, DF; Hsu, CY; Martin, RL; Moy, CS; Palesch, YY; Qureshi, AI; Silbergleit, R; Steiner, T; Suarez, JI; Toyoda, K; Wang, Y; Yamamoto, H; Yoon, BW, 2016) |
| "Fifty-two subjects were prospectively randomized to receive either nicardipine or esmolol as the sole drug for treatment of emergence hypertension at the conclusion of brain tumor resection (40 subjects finally analyzed)." | 5.20 | Nicardipine is superior to esmolol for the management of postcraniotomy emergence hypertension: a randomized open-label study. ( Badri, AM; Bebawy, JF; Carabini, LM; Gupta, DK; Hemmer, LB; Houston, CC; Koht, A; Kosky, JL; Moreland, NC, 2015) |
| "Determine the definitive position of ketanserin and dihydralazine for treatment of severe hypertension in pregnancy." | 5.20 | Ketanserin versus dihydralazine for the treatment of severe hypertension in early-onset preeclampsia: a double blind randomized controlled trial. ( Bijvank, SW; Duvekot, JJ; Edens, MA; Hanff, LM; Roofthooft, DW; Steegers, EA; Visser, W; Vulto, AG, 2015) |
| " Food and Drug Administration (FDA)-recommended doses of labetalol and nicardipine for hypertension (HTN) management in a subset of patients with renal dysfunction (RD)." | 5.19 | The management of acute hypertension in patients with renal dysfunction: labetalol or nicardipine? ( Baumann, BM; Borczuk, P; Cannon, CM; Chandra, A; Cline, DM; Diercks, DB; Hiestand, B; Hsu, A; Jois-Bilowich, P; Kaminski, B; Levy, P; Nowak, RM; Peacock, WF; Schrock, JW; Soto-Ruiz, KM; Varon, J, 2014) |
| "This is a prospective, pseudo-randomized study comparing labetalol and nicardipine for blood pressure (BP) management in acute stroke patients." | 5.17 | A prospective evaluation of labetalol versus nicardipine for blood pressure management in patients with acute stroke. ( Coplin, W; Levy, PD; Liu-DeRyke, X; Parker, D; Rhoney, DH, 2013) |
| "Our study suggests that nicardipine is a more effective antihypertensive agent than labetalol in an unselected group of patients who develop hypertension in the intensive care unit setting." | 5.16 | Intravenous labetalol compared with intravenous nicardipine in the management of hypertension in critically ill patients. ( Hilleman, DE; Malesker, MA, 2012) |
| " In parts I and II, the number of patients who required additional doses of the study drug because of persistent hypertension was lower in the nicardipine groups than in the labetalol groups (P < 0." | 5.16 | Comparative prophylactic and therapeutic effects of intravenous labetalol 0.4 mg/kg and nicardipine 20 μg/kg on hypertensive responses to endotracheal intubation in patients undergoing elective surgeries with general anesthesia: a prospective, randomized, ( Apfel, CC; Do, SH; Hwang, JW; Jeon, YT; Kim, CS; Ro, YJ; Ryu, JH; Whelan, R, 2012) |
| "Our purpose was to compare the safety and efficacy of food and drug administration (FDA) recommended dosing of IV nicardipine versus IV labetalol for the management of acute hypertension." | 5.15 | CLUE: a randomized comparative effectiveness trial of IV nicardipine versus labetalol use in the emergency department. ( Baumann, BM; Borczuk, P; Cannon, CM; Chandra, A; Cline, DM; Diercks, D; Hiestand, B; Hsu, A; Jois-Bilowich, P; Kaminski, B; Levy, P; Nowak, RM; Peacock, WF; Schrock, JW; Varon, J, 2011) |
| "The calcium channel blocker nicardipine (NC) is effective for acute control of hypertension." | 5.13 | Prospective randomized comparison of safety and efficacy of nicardipine and nitroprusside drip for control of hypertension in the neurosurgical intensive care unit. ( Alaraj, A; Hardman, J; Mangubat, EZ; Merchant, A; Mlinarevich, N; Roitberg, BZ; Ruland, S; Urbaniak, K; Watson, KS, 2008) |
| "To assess the efficacy and safety of nicardipine in comparison to labetalol in the initial management of severe hypertension in pregnancy." | 5.10 | Short-term treatment of severe hypertension of pregnancy: prospective comparison of nicardipine and labetalol. ( Abroug, F; Boussarssar, M; Elatrous, S; Marghli, S; Nouira, S; Ouanes Besbes, L; Sakkouhi, M, 2002) |
| "A 90-day, multicenter, randomized, double-blind, parallel-group study was conducted to compare the efficacy of amlodipine (once a day) with nicardipine (two to three times a day), in the treatment of isolated systolic hypertension (ISH) in the elderly." | 5.10 | Randomized, comparative, double-blind study of amlodipine vs. nicardipine as a treatment of isolated systolic hypertension in the elderly. ( Bernaud, C; Carre, A; Clerson, P; Emeriau, JP; Jaboureck, O; Mounier-Véhier, C, 2002) |
| "Diltiazem and nicardipine, when injected as a mixture during anesthesia, reduce blood pressure in an additive manner without changing heart rate." | 5.10 | Combined administration of diltiazem and nicardipine attenuates hypertensive responses to emergence and extubation. ( Tsutsui, T, 2002) |
| "Compare the efficacy of isradipine to that of nicardipine for the control of arterial hypertension following coronary artery bypass graft (CABG)." | 5.10 | [Comparison of nicardipine and isradipine in hypertension following coronary artery bypass graft]. ( Achkouty, R; Antakly, MC; Haddad, F; Hayek, G; Khater-Rassi, D; Madi-Jebara, S; Yazigi, A, 2002) |
| "We compared the efficacy of the combination of enalaprilat/labetalol with that of enalaprilat/nicardipine to prevent emergence postcraniotomy hypertension." | 5.09 | A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery. ( Broad, C; Ferri, E; Kross, RA; Leung, D; Melendez, JA; Pratila, M; Veronesi, M, 2000) |
| "To evaluate the effectiveness of nicardipine and nitroprusside for breakthrough hypertension following carotid endarterectomy." | 5.09 | Nicardipine versus nitroprusside for breakthrough hypertension following carotid endarterectomy. ( Breslow, MJ; Dorman, T; Lipsett, PA; Rosenfeld, BA; Thompson, DA, 2001) |
| "Intravenous nicardipine titration, starting with 10 mg/hr and increased slowly every 4 minutes by the rate 1 mg/hr until target supine DBP of 90 mmHg was achieved, was a very effective and safe method for patients with very severe hypertension." | 5.08 | Intravenous nicardipine for the treatment of severe hypertension. A dose-titration infusion to therapeutic response. ( Sukonthasarn, A, 1995) |
| "This study was a prospective, randomized, double-blind, placebo-controlled clinical trial designed to evaluate the safety and efficacy of oral nicardipine for the treatment of urgent hypertension in the emergency department." | 5.08 | Evaluation of the efficacy and safety of oral nicardipine in treatment of urgent hypertension: a multicenter, randomized, double-blind, parallel, placebo-controlled clinical trial. ( Dunbar, LM; Friday, KJ; Habib, GB; Neale, AC; Rodrigues, R, 1995) |
| "To compare the efficacy of intravenous (iv) nicardipine with nitroglycerin for the treatment for patients with perioperative hypertension." | 5.08 | Comparison of antihypertensive effects of nicardipine with nitroglycerin for perioperative hypertension. ( Chen, TL; Cheng, YJ; Lee, TS; Lin, CJ; Lin, SY; Sun, WZ, 1995) |
| "Eight preterm infants were given intravenous nicardipine, a calcium channel blocker, to treat systemic hypertension (renal artery thrombosis (n = 3); dexamethasone for management of bronchopulmonary dysplasia (n = 2); unexplained (n = 3)." | 5.08 | Intravenous nicardipine in hypertensive preterm infants. ( Françoise, M; Geneste, B; Germain, JF; Gouyon, JB; Semama, DS, 1997) |
| "The aim of this study was to compare the effects of a calcium antagonist, nicardipine SR, with an angiotensin-converting enzyme (ACE) inhibitor, alacepril, on the regression of left ventricular hypertrophy (LVH) and function." | 5.08 | Both a calcium antagonist and ACE inhibitor reverse hypertrophy in hypertension but a calcium antagonist also depresses contractility. ( Hiwada, K; Ito, T; Joh, T; Muneta, S; Ochi, T; Sumimoto, T, 1997) |
| "The primary objective of this study was to compare the antihypertensive efficacy and safety of intravenously administered nicardipine with that of intravenous nitroprusside (SNP) in patients with severe hypertension." | 5.07 | A comparison of intravenous nicardipine and sodium nitroprusside in the immediate treatment of severe hypertension. ( Cook, E; Fletcher, E; Grandy, S; Lee, R; Maher, KE; Neutel, JM; Ram, CV; Smith, DH; Turlepaty, P; Wallin, D, 1994) |
| "To compare the effects of treatment with nicardipine and metoprolol in patients with hypertension during pregnancy." | 5.07 | Nicardipine versus metoprolol in the treatment of hypertension during pregnancy: a randomized comparative trial. ( Carbonne, B; Jannet, D; Milliez, J; Sebban, E, 1994) |
| "We performed a randomized, crossover study comparing the effects of nicardipine and trichlormethiazide on insulin sensitivity in 8 untreated essential hypertensive patients." | 5.07 | Comparison of effects of nicardipine and trichlormethiazide on insulin sensitivity in hypertensive patients. ( Fujita, T; Ishibashi, K; Isogai, Y; Kageyama, S; Mimura, A; Sakurai, T; Yamamoto, J; Yokota, K, 1994) |
| "9 years, suffering from slight or moderate arterial hypertension were treated with either 40 mg of Nicardipine retard twice a day (b." | 5.07 | [Slow-release nicardipine in the treatment of arterial hypertension: comparative study vs. an ACE inhibitor]. ( Adriani, A; Bonfantino, V; De Cesaris, R; Ferrieri, A; Filitti, V; Ranieri, G, 1993) |
| "Sustained-release nicardipine at a dose of 30 to 60 mg every 12 h provided effective and generally well-tolerated antihypertensive control throughout the day in most patients with mild-to-moderate essential hypertension." | 5.07 | Sustained-release nicardipine in mild-to-moderate hypertension. ( Fagan, TC; Kenley, S; Reitman, MA; Tyler, ED; Weber, MA, 1993) |
| "Forty pregnant patients with mild or moderate hypertension received oral nicardipine 20 mg three times a day (mean duration of treatment 9 +/- 2." | 5.07 | Nicardipine treatment of hypertension during pregnancy. ( Carbonne, B; Jannet, D; Khelifati, Y; Milliez, J; Touboul, C, 1993) |
| "The purpose of this placebo-control, double-blind, randomized and crossover study is to evaluate the effect of nicardipine and nifedipine in Chinese senile hypertension." | 5.07 | [Comparison of nicardipine and nifedipine in treatment of Chinese senile hypertension placebo-control, double-blind, randomized and crossover study]. ( Chang, MS; Chen, CH; Chen, JW; Wang, SP, 1992) |
| "The effect of manidipine, a new Ca2+ antagonist, on intrarenal hemodynamics was assessed in essential hypertension and compared with nicardipine, a previously studied Ca2+ antagonist." | 5.07 | Effect of manidipine, a new calcium antagonist, on intrarenal hemodynamics in essential hypertension. ( Abe, H; Ashida, T; Imanishi, M; Kawano, Y; Kimura, G; Kojima, S; Murakami, K; Sanai, T; Yoshida, K; Yoshimi, H, 1992) |
| "This study used 2D Doppler flowmetry to assess the effects on peripheral hemodynamics of effective treatment with nicardipine or atenolol in 40 patients with mild or moderate essential hypertension." | 5.07 | Large artery compliance in essential hypertension. Effects of calcium antagonism and beta-blocking. ( Andriani, A; De Cesaris, R; Filitti, V; Ranieri, G, 1992) |
| "A controlled, randomized, single-blind, parallel-group study compared the effects of nicardipine hydrochloride/hydrochlorothiazide (HCTZ) with those of pindolol/HCTZ in treatment of essential hypertension." | 5.07 | A comparative study of nicardipine and pindolol as second-line treatments in essential hypertension. ( Huikko, M; Jounela, A; Kanniainen, E; Penttila, O, 1992) |
| " Hypertension during gastrectomy was treated by increasing the concentration of enflurane, by nicardipine infusion (0." | 5.07 | Treatment of intraoperative hypertension with enflurane, nicardipine, or human atrial natriuretic peptide: haemodynamic and renal effects. ( Goto, F; Kato, S; Sudo, I, 1992) |
| "To compare the efficacy and safety of iv nicardipine with sodium nitroprusside in the treatment of postoperative hypertension after both cardiac and noncardiac surgery." | 5.07 | Postoperative hypertension: a multicenter, prospective, randomized comparison between intravenous nicardipine and sodium nitroprusside. ( Floyd, J; Gabrielson, G; Goldberg, JS; Goldberg, M; Greenstein, RJ; Halpern, NA; Neely, C; Sladen, RN, 1992) |
| "The efficacy and tolerability of nicardipine retard and captopril were assessed in 174 over-60-year-olds suffering from slight or moderate essential hypertension." | 5.07 | [Efficacy and tolerability of nicardipine retard and captopril in hypertension in the aged. Results of a multicenter study]. ( Buoninconti, R; Errico, M; Freda, M; Giordano, MP; Granata, Q; Lucentini, ML; Mancia, G; Marsili, P; Pasotti, C; Piccolo, E, 1992) |
| "In this double-blind, parallel, multicenter study, sustained-release (SR) preparations of 2 calcium antagonists, nicardipine and verapamil, were compared for the treatment of mild to moderate systemic hypertension." | 5.07 | Comparison of sustained-release formulations of nicardipine and verapamil for mild to moderate systemic hypertension. ( Friday, KJ; Frishman, WH; Gradman, AH; Kaihlanen, PM; Wong, SC, 1992) |
| "The effect of the calcium antagonist nicardipine on insulin secretion and glucose homoeostasis was investigated in elderly hypertensives with and without diabetes mellitus; 15 patients with essential hypertension for at least 10 years and normal glucose tolerance according to standard criteria (Group I) and 15 elderly hypertensive patients affected by Type 2 diabetes mellitus and on treatment with diet or oral drugs (Group 2)." | 5.07 | Nicardipine does not cause deterioration of glucose homoeostasis in man: a placebo controlled study in elderly hypertensives with and without diabetes mellitus. ( Ceriello, A; D'Onofrio, F; Giugliano, D; Paolisso, G; Saccomanno, F; Torella, R; Varricchio, M, 1992) |
| "The effects of a sustained-release formulation of the calcium antagonist nicardipine on left ventricular (LV) mass, Doppler transmitral velocity profiles and plasma neurohumoral studies were analyzed in patients with mild to moderate systemic hypertension." | 5.07 | Effects of sustained-release nicardipine on regression of left ventricular hypertrophy in systemic hypertension. ( Adler, J; Dittrich, HC; Ong, J; Reitman, M; Weber, M; Ziegler, M, 1992) |
| "The extent and duration of the blood pressure (BP) lowering effect of 20 mg nitrendipine (NIT) once daily and 40 mg nicardipine slow release (NIC) twice daily were compared in 12 men (aged 39-55 years) with mild essential hypertension according to a randomized, cross over study." | 5.07 | Nitrendipine 20 mg once daily versus nicardipine slow release 40 mg twice daily in mild essential hypertension: evaluation by 24-hour ambulatory blood pressure monitoring. ( Borgnino, C; Corradi, L; Fogari, R; Malamani, GD; Poletti, L; Tettamanti, F; Zoppi, A, 1992) |
| "In an open, randomized, multicenter trial, intravenous nicardipine was compared with sodium nitroprusside in 74 patients with hypertension (mean arterial pressure [MAP] greater than or equal to 100 mm Hg) following coronary artery bypass surgery." | 5.07 | Comparison of nicardipine and sodium nitroprusside in the treatment of paroxysmal hypertension following aortocoronary bypass surgery. ( David, D; Dubois, C; Loria, Y, 1991) |
| "The main aim of this study was to investigate whether a new slow-release formation of nicardipine can control hypertension and whether its antihypertensive effect is manifest throughout the dose intervals." | 5.07 | Double-blind, randomized comparative study of the antihypertensive effect of nicardipine slow-release and nifedipine slow-release in hypertensive patients with coronary heart disease. ( Glocke, MH; Griebel, A; Maetzel, FK; Teufel, WE, 1991) |
| "The effects of nicardipine and propranolol on patients' quality of life were compared during a double-blind, multicentre, parallel, randomised study of hypertension therapy." | 5.07 | Nicardipine as antihypertensive monotherapy: positive effects on quality of life. ( Champion, D; Ekelund, LG; Josselson, J; Korc, M; Pool, JL; Stein, GH; Weir, MR; Wolbach, RA, 1991) |
| " A novel formulation of nicardipine (25% standard, 75% sustained release--SR) was evaluated in mild hypertension in a double-blind, randomized, placebo-controlled comparison with standard nicardipine (STD), using clinic measurements (Hawksley) augmented by home recorded blood pressures (Copal UA 251)." | 5.07 | Nicardipine sustained release in hypertension. ( Beard, M; Crichton, W; Dow, RJ; Jamieson, M; Jeffers, TA; MacDonald, FC; Petrie, JC; Roy-Chaudhury, P; Webster, J; Witte, K, 1991) |
| "The effects of a calcium-entry blocker, nicardipine, on intrarenal hemodynamics were studied in essential hypertension." | 5.07 | Effect of a calcium-entry blocker, nicardipine, on intrarenal hemodynamics in essential hypertension. ( Abe, H; Ashida, T; Deguchi, F; Imanishi, M; Kawamura, M; Kawano, Y; Kimura, G; Kojima, S; Yoshida, K; Yoshimi, H, 1991) |
| "In a double-blind, randomized, multicenter study, the efficacy and safety of intravenous (IV) nicardipine was compared with placebo in the control of postoperative hypertension in cardiac and noncardiac surgical patients." | 5.07 | Efficacy and safety of intravenous nicardipine in the control of postoperative hypertension. IV Nicardipine Study Group. ( , 1991) |
| "A double-blind, placebo-controlled study was carried out over 120 days to assess the metabolic tolerance and patient acceptability of nicardipine in 20 patients with Type 2 diabetes mellitus and slight hypertension." | 5.06 | The influence of nicardipine in type 2 diabetic patients with slight hypertension. ( Faguer de Moustier, B; Paoli, V, 1990) |
| "Nicardipine, a new dihydropyridine calcium channel blocking agent, has been shown to be effective in the management of hypertension." | 5.06 | Adrenergic response to nicardipine in the management of postoperative hypertension. ( Meacham, PW; Perry, SM; Smith, DW; Wood, M, 1990) |
| "Nicardipine hydrochloride, a new calcium channel blocker for intravenous use, has been compared with placebo in a prospective, randomized, double-blind trial on postoperative hypertension." | 5.06 | Postoperative hypertension: a prospective, placebo-controlled, randomized, double-blind trial, with intravenous nicardipine hydrochloride. ( Alicea, M; Greenstein, R; Halpern, NA; Krakoff, LR, 1990) |
| "The aim of the study was to compare the effect of slow-release (SR) nicardipine, placebo and chlorthalidone on hypertension-related arrhythmias evaluating 24-h ambulatory ECG." | 5.06 | Hypertension and arrhythmias: effects of slow-release nicardipine vs chlorthalidone: a double-blind crossover study. ( Celentano, A; de Divitiis, O; Galderisi, M; Garofalo, M; Mureddu, GF; Tammaro, P, 1990) |
| "Nicardipine hydrochloride was administered intravenously to two groups of hypertensive patients: one group of 37 patients with mild to moderate hypertension and one group of 20 patients with severe hypertension." | 5.06 | Pharmacokinetics, pharmacodynamics, and minimum effective clinical dose of intravenous nicardipine. ( Bienvenu, G; Clifton, GG; Cook, E; Grandy, S; Lai, CM; McMahon, G; Quon, C; Sambol, N; Vargas, R; Williams, R, 1990) |
| "The antihypertensive effect of slow-release (SR) nicardipine (40 mg twice a day) and chlorthalidone (25 mg once a day), was evaluated in 36 patients with mild to moderate hypertension by casual and 24-h BP monitoring." | 5.06 | Effects on casual and 24-h ambulatory blood pressure of slow-release nicardipine and chlorthalidone in arterial essential hypertension: double-blind, crossover study. ( Celentano, A; de Divitiis, O; Galderisi, M; Garofalo, M; Mureddu, GF; Tammaro, P, 1990) |
| "Nicardipine hydrochloride, a dihydropyridine calcium entry-blocking drug, was administered to 66 patients with severe hypertension during three protocols designed to examine the efficacy and safety of this investigation drug." | 5.06 | Intravenous nicardipine hydrochloride: treatment of patients with severe hypertension. ( Wallin, JD, 1990) |
| ") nicardipine hydrochloride (a calcium antagonist) compared with nitroglycerin, the drug generally used for treatment of hypertension after coronary artery bypass grafting, was tested in 20 postoperative patients." | 5.06 | Comparison of intravenous nicardipine and nitroglycerin to control systemic hypertension after coronary artery bypass grafting. ( Gibson, DG; Lennox, SC; Nicolaides, EP; Swanson, KT; Vecht, RJ, 1989) |
| "The purpose of the study was to evaluate the effects of a dihydropyridine calcium antagonist, nicardipine (N), on blood pressure (BP) and aldosterone secretion in hypertensive patients (pt) with primary aldosteronism." | 5.06 | [Effect of a calcium inhibitor, nicardipine, on aldosterone secretion in primary hyperaldosteronism]. ( Begasse, F; Chamontin, B; David, D; Salvador, M, 1989) |
| "Seven of eight hypertensive Type 2 (non-insulin-dependent) diabetic patients with microalbuminuria completed a randomised crossover trial to compare the renal effects of angiotensin converting enzyme inhibitor (enalapril) and calcium antagonist (nicardipine)." | 5.06 | Comparison of the renal effects of angiotensin converting enzyme inhibitor and calcium antagonist in hypertensive type 2 (non-insulin-dependent) diabetic patients with microalbuminuria: a randomised controlled trial. ( Baba, T; Murabayashi, S; Takebe, K, 1989) |
| "The antihypertensive effect of nicardipine was evaluated in 89 ambulatory elderly patients with hypertension through a multicenter trial enrolling patients over the age of 65 years." | 5.06 | Nicardipine monotherapy in ambulatory elderly patients with hypertension. ( Krakoff, LR, 1989) |
| " We evaluated the relative efficacies and tolerability of various low-dose combinations of nicardipine and propranolol in patients with mild-moderate essential hypertension (DBP Phase V of greater than 90-125 mmHg; WHO Grades I and II) in order to select the best one." | 5.06 | Comparison of the efficacy and acceptability of nicardipine and propranolol, alone and in combination, in mild to moderate hypertension. ( Dow, RJ; Gough, KJ; Laing, EM; Macdonald, FC; Maclean, D; McDevitt, DG; Mitchell, ET, 1989) |
| "The efficacy of nicardipine vs nitroprusside in controlling hypertension after sternotomy was compared in 120 patients undergoing coronary artery bypass grafting and anesthetized with fentanyl (100 micrograms/kg)." | 5.06 | Antihypertensive and anti-ischemic effects of nicardipine and nitroprusside in patients undergoing coronary artery bypass grafting. ( Deen, L; Dijkhuis, JP; Koolen, JJ; Moulijn, AC; van Wezel, HB; Vergroesen, I; Visser, CA, 1989) |
| "Sixty-six patients with severe hypertension were treated with intravenous nicardipine in 3 separate protocols." | 5.06 | Intravenous nicardipine in severe systemic hypertension. ( Bienvenu, GS; Clifton, GG; Cook, ME; Wallin, JD, 1989) |
| "Nicardipine was administered orally for up to 1 year to 250 patients with essential hypertension." | 5.06 | Long-term systemic arterial blood pressure control with nicardipine. ( Castle, CH; Wolbach, RA, 1989) |
| "A placebo-controlled, double-blind multicenter trial was conducted in 123 patients with severe hypertension to examine the efficacy and safety of intravenously administered nicardipine hydrochloride in controlling blood pressure." | 5.06 | Intravenous nicardipine for the treatment of severe hypertension. A double-blind, placebo-controlled multicenter trial. ( Cheung, DG; Cook, ME; Davis, WR; Fletcher, E; Langford, HG; MacCarthy, EP; Ram, CV; Saunders, E; Townsend, R; Wallin, JD, 1989) |
| " A novel formulation of nicardipine (50% standard (short acting), 50% sustained release) was evaluated in mild hypertension in a double-blind, randomized, placebo-controlled study, using clinic measurements (Hawksley) augmented by home recorded blood pressures (Copal UA 251)." | 5.06 | Evaluation of a long acting formulation of nicardipine in hypertension by clinic and home recorded blood pressures and Doppler aortovelography. ( Jeffers, TA; Petrie, JC; Rawles, J; Webster, J; Witte, K, 1989) |
| "The effect of adding placebo, a calcium antagonist, nicardipine and a thiazide diuretic, chlorthalidone, each for 2 weeks, to ongoing treatment with the ACE inhibitor, enalapril was evaluated in seven patients with essential hypertension." | 5.06 | Enalapril in essential hypertension: the comparative effects of additional placebo, nicardipine and chlorthalidone. ( Donnelly, R; Elliott, HL; Meredith, PA; Reid, JL, 1987) |
| "The two dihydropyridine calcium antagonists, nicardipine and nifedipine, were compared in 12 patients with both stable angina pectoris and systemic hypertension using a double-blind, crossover protocol." | 5.06 | A randomized double-blind crossover study of nicardipine and nifedipine in patients with angina pectoris and concomitant essential hypertension. ( Bonandi, L; Dei Cas, L; Feroldi, P; Metra, M; Nodari, S; Nordio, G; Raddino, R; Visioli, O, 1988) |
| "Nicardipine is currently being evaluated in clinical trials as a treatment for angina and hypertension." | 5.06 | An overview of the safety and efficacy of nicardipine in clinical trials. ( Agre, K, 1987) |
| "Thirty patients with mild to moderate essential hypertension entered a randomised double-blind parallel group study for 6 months to compare the effects of the new calcium channel blocker nicardipine 90 mg/day and propranolol 240 mg/day." | 5.06 | Nicardipine in the treatment of essential hypertension controlled 6-month-study comparing nicardipine with propranolol at rest and during exercise. ( Bjerle, P; Danielsson, A; Ek, B; Steen, L; Suhr, O, 1987) |
| "In a double-blind controlled trial 22 patients with mild or moderate essential hypertension were treated with nicardipine 30 mg t." | 5.06 | Comparison of nicardipine and propranolol in the treatment of mild and moderate hypertension. ( Karppinen, K; Naukkarinen, VA; Sarna, S, 1987) |
| "Thirty-nine patients with mild to moderate essential hypertension participated in a parallel, single-blind study comparing 6 weeks' treatment of nicardipine hydrochloride (90 mg/day) with nifedipine (40 mg/day)." | 5.06 | Comparison of the efficacy of nicardipine, a new calcium channel blocker, with nifedipine in the treatment of mild to moderate essential hypertension. ( Armstrong, C; Blackwood, R; Garnham, J, 1987) |
| "We studied the renal effects of nicardipine, a calcium entry blocker, in eight patients with essential hypertension (group A, WHO I or II), six hypertensive type II diabetics with mild-to-moderate nephropathy (group B, urinary albumin 200-789 mg/day), and six hypertensive type II diabetics with severe or advanced nephropathy (group C, urinary albumin 1,596-4,300 mg/day)." | 5.06 | Renal effects of nicardipine, a calcium entry blocker, in hypertensive type II diabetic patients with nephropathy. ( Aoyagi, K; Baba, T; Ido, Y; Ishizaki, T; Murabayashi, S; Takebe, K, 1986) |
| "The antihypertensive effect of twice-daily nicardipine, an investigational calcium-channel blocker, was evaluated in a placebo-controlled, single-blind trial in 18 adult patients with essential hypertension (supine diastolic blood pressure [BP] of greater than or equal to 95 and less than or equal to 120 mmHg)." | 5.06 | Twice-daily nicardipine in the treatment of essential hypertension. ( Charlap, S; Dorsa, F; Kafka, K; Kimmel, B; Laifer, L; Lazar, E; Saltzberg, S; Singer, M; Strom, J; Weinberg, P, 1986) |
| "A twelve-week parallel study was conducted to compare the efficacy and safety of nicardipine plus propranolol with that of propranolol alone in 67 patients with mild to moderate essential hypertension." | 5.06 | Comparison of concomitant nicardipine hydrochloride and propranolol with propranolol alone in patients with essential hypertension. ( Douglas-Jones, AP; Havard, CW; Nievel, JG, 1987) |
| "We studied the renal effects of nicardipine, a calcium entry blocker, in seven patients with mild-to-moderate essential hypertension." | 5.06 | Renal effects of nicardipine in patients with mild-to-moderate essential hypertension. ( Baba, T; Boku, A; Ishizaki, T; Sone, K; Takebe, K, 1986) |
| "A systematic review of published manuscripts was performed to identify studies of patients who received sodium nitroprusside and nicardipine as part of the treatment for arterial hypertension or afterload reduction after cardiac surgery." | 5.05 | Sodium nitroprusside versus nicardipine for hypertension management after surgery: A systematic review and meta-analysis. ( Bronicki, RA; Flores, S; Iranpour, N; Kriz, C; Loomba, RS; Villarreal, EG, 2020) |
| "Fifty patients with mild essential (primary) hypertension entered a double-blind, parallel-group study with either nicardipine 30 mg three times daily or placebo, randomly assigned as monotherapy for 6 weeks." | 5.05 | Nicardipine hydrochloride in essential hypertension--a controlled study. ( Asplund, J, 1985) |
| "The dose-response effects of oral nicardipine on the systemic blood pressure were examined in 54 patients with uncomplicated essential hypertension (DBP greater than or equal to 100 mm Hg)." | 5.05 | Anti-hypertensive dose-response effects of nicardipine in stable essential hypertension. ( Frais, MA; Jackson, N; Lee, P; Silke, B; Taylor, SH; Verma, SP, 1985) |
| " Therefore, we analyzed the potency and side effects of two treatment options (nicardipine compared to labetalol) in order to gain insight in improved treatment of severe hypertension during pregnancy and to evaluate the feasibility of a randomised controlled trial." | 4.90 | The optimal treatment of severe hypertension in pregnancy: update of the role of nicardipine. ( de Groot, CJ; Meuleman, T; Nooij, LS; Roelofs, R; Visser, S; Vos, P, 2014) |
| " Extended-release nifedipine and amlodipine are the two most commonly used oral CCAs in the management of pediatric hypertension." | 4.83 | A review of calcium channel antagonists in the treatment of pediatric hypertension. ( Sahney, S, 2006) |
| " Hydralazine has been widely used in treatment of hypertension in eclampsia and preeclampsia, and its safety has been demonstrated in these patients." | 4.79 | Management of hypertensive urgencies and emergencies. ( Abdelwahab, W; Frishman, W; Landau, A, 1995) |
| " Although the role of antihypertensive therapy in regression of LVH remains controversial, the calcium antagonist nicardipine appears to have an important role to play in the treatment of LVH in hypertension and in congestive heart failure." | 4.78 | Therapeutic advances in the treatment of left ventricular hypertrophy. ( Natsume, T, 1993) |
| "Nicardipine is an antagonist of calcium influx through the slow channel of the cell membrane and has been shown to be an effective and relatively well-tolerated treatment for stable effort angina and rest angina due to coronary artery spasm, and mild to moderate hypertension." | 4.77 | Nicardipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in the treatment of angina pectoris, hypertension and related cardiovascular disorders. ( Clissold, SP; Sorkin, EM, 1987) |
| "In patients with hemorrhagic stroke, nicardipine appeared to have similar efficacy as clevidipine in SBP reduction, with a more likely reduction of rebound hypertension and drug cost." | 4.12 | Comparison of Clevidipine and Nicardipine for Acute Blood Pressure Reduction in Hemorrhagic Stroke. ( Breslin, J; Hanify, J; Heierman, T; Larizadeh, K; Phipps, W; Saldana, S; Sanchez, M, 2022) |
| "This multicenter, retrospective case series included all pregnant women beyond 20 weeks of gestation with severe antepartum hypertension that were treated with intravenous nicardipine." | 4.12 | Nicardipine for treating severe antepartum hypertension during pregnancy: Nine years of experience in more than 800 women. ( Cornette, JC; Duvekot, JJ; Edens, MA; Hengst, M; Huigen, S; Nij Bijvank, SW; Winkelen, AV, 2022) |
| " We present a case report of a patient with refractory hypertension to high dose nitrates likely due to nitroglycerin resistance or an attenuated response." | 4.02 | Nicardipine: When high dose nitrates fail in treating heart failure. ( O'Connell, TW; Raggi, JR; Singer, DJ, 2021) |
| "Nicardipine is an antihypertensive drug that may be used off-label by oral route to treat hypertension in children." | 4.02 | Stability study of a compounded oral solution of nicardipine for the treatment of hypertension in children. ( Buchbinder, N; Colnot, M; Coquard, A; Fuss, D; Gondé, H; Hervouët, C; Lamoureux, F; Pereira, T; Varin, R, 2021) |
| "The aim of this study was to compare radial arterial catheter-derived pressure with oscillometric blood pressure in women with severe peripartum hypertension undergoing urgent treatment with intravenous nicardipine at a maternal intensive care unit." | 4.02 | Intra-arterial versus oscillometric blood pressure measurements in women with severe peripartum hypertension undergoing urgent treatment with nicardipine: An observational study. ( Gan, S; Lan, L; Li, L; Qi, H; Qin, J; Ren, L; Xiang, B; Yan, Y; Zhang, Y, 2021) |
| "To assess the safety and efficacy of continuous infusion (CIV)-labetalol compared to -nicardipine in controlling blood pressure (BP) in the acute stroke setting." | 4.02 | Blood Pressure Control in Acute Stroke: Labetalol or Nicardipine? ( El-Ghoroury, H; Hecht, JP; Sudekum, DM, 2021) |
| "To investigate the efficacy of low-dose intravenous nicardipine for emergent management of severe postpartum hypertension in maternal intensive care units (ICUs)." | 3.96 | Efficacy of low-dose nicardipine for emergent treatment of severe postpartum hypertension in maternal intensive care units: An observational study. ( Gan, S; Lan, L; Li, L; Qi, H; Qin, J; Ren, L; Yan, Y; Zhang, Y, 2020) |
| " Nicardipine and labetalol are commonly administered for the treatment of acute hypertension following stroke." | 3.91 | Nicardipine Associated Risk of Short-Term Mortality in Critically Ill Patients with Ischemic Stroke. ( Desai, A; Hanni, C; Mohamed, W; Parker, D; Saber, H; Sadeghi, M; Singh, A, 2019) |
| "Labetalol and nicardipine are antihypertensives commonly used in the management of elevated blood pressure (BP) following an acute stroke, but there is limited evidence to suggest which agent as a continuous infusion should be used preferentially in this setting." | 3.88 | Continuous-Infusion Labetalol vs Nicardipine for Hypertension Management in Stroke Patients. ( Hecht, JP; Richards, PG, 2018) |
| "Nicardipine is frequently used in the treatment of hypertension for patients with acute stroke; however, its dosing is complicated by a high risk of phlebitis." | 3.88 | Reduction of Nicardipine-Related Phlebitis in Patients with Acute Stroke by Diluting Its Concentration. ( Kawada, K; Miyamoto, N; Ohta, T; Tanaka, K, 2018) |
| "This retrospective review compared nicardipine with clevidipine for hypertension in acute stroke patients from March 17, 2015 to December 23, 2016." | 3.88 | Comparison of Nicardipine with Clevidipine in the Management of Hypertension in Acute Cerebrovascular Diseases. ( Conklen, K; Deshpande, M; Ferrill, D; Jones, B; Rosenfeldt, Z; Siddiqui, FM, 2018) |
| "The Stroke Acute Management with Urgent Risk-factor Assessment and Improvement (SAMURAI)-ICH Study was a multicenter, prospective, observational study investigating the safety and feasibility of early (within 3 h from onset) reduction of systolic BP (SBP) to < 160 mm Hg with intravenous nicardipine for acute hypertension in cases of spontaneous ICH." | 3.88 | Early Achievement of Blood Pressure Lowering and Hematoma Growth in Acute Intracerebral Hemorrhage: Stroke Acute Management with Urgent Risk-Factor Assessment and Improvement-Intracerebral Hemorrhage Study. ( Ando, D; Fujita, K; Hasegawa, Y; Ide, T; Itabashi, R; Kamimura, T; Kamiyama, K; Kario, K; Kimura, K; Koga, M; Kumamoto, M; Matsubara, S; Nagatsuka, K; Okada, Y; Okuda, S; Sato, S; Shiokawa, Y; Shiozawa, M; Todo, K; Toyoda, K; Yamagami, H; Yamaguchi, Y; Yoshimoto, T; Yoshimura, S, 2018) |
| "Ten severely pre-eclamptic pregnant women who required intravenous nicardipine for severe hypertension were included in this prospective observational trial." | 3.83 | Hemodynamic effects of intravenous nicardipine in severely pre-eclamptic women with a hypertensive crisis. ( Buijs, EA; Cornette, J; Duvekot, JJ; Herzog, E; Meima, M; Rizopoulos, D; Roos-Hesselink, JW; Steegers, EA, 2016) |
| "Nicardipine is a dihydropyridine calcium-channel blocker that is frequently used in the acute treatment of hypertension in the emergency department (ED)." | 3.83 | Bradycardia caused by intravenous nicardipine in an elderly patient with acute ischemic infarct. ( Abboud, ME; Frasure, SE, 2016) |
| "We performed a retrospective review of children recovering from aortic coarctectomy or superior cavopulmonary anastomoses who received nicardipine for hypertension at our institution between 2007 and 2013." | 3.83 | Nicardipine for Hypertension Following Aortic Coarctectomy or Superior Cavopulmonary Anastomosis. ( Arango Uribe, D; Mastropietro, CW, 2016) |
| "Intravenous nicardipine is generally used to treat hypertension in acute stroke patients but is associated with frequent phlebitis." | 3.83 | Risk Factors of Nicardipine-Related Phlebitis in Acute Stroke Patients. ( Kadoguchi, N; Kawada, K; Morimoto, M; Ohta, T; Tanaka, K; Yamamoto, S, 2016) |
| "This study aimed to compare the effects of labetalol, nicardipine, or hydralazine on time to target blood pressure before alteplase administration in patients with acute ischemic stroke." | 3.81 | Time to Blood Pressure Control Before Thrombolytic Therapy in Patients With Acute Ischemic Stroke: Comparison of Labetalol, Nicardipine, and Hydralazine. ( Cortes, J; Hall, AB; McKay, C, 2015) |
| "To examine the impact of intravenous antihypertensive selection on hospital health resource utilization using data from the Evaluation of CLevidipine In the Perioperative Treatment of Hypertension Assessing Safety Events (ECLIPSE) trials." | 3.80 | A cost analysis of the impact of a new intravenous antihypertensive in managing perioperative blood pressure during cardiac surgery. ( Aronson, S; Crothers, TA; Dasta, JF; Fontes, M; Levy, JH; Lumb, PD; Navetta, MS; Sulham, KA; Wang, Y, 2014) |
| "Cyclosporine (CsA) is frequently responsible for hypertension in bone marrow transplant children." | 3.80 | Pharmacokinetic drug-drug interaction of calcium channel blockers with cyclosporine in hematopoietic stem cell transplant children. ( Bernard, E; Bertrand, Y; Bleyzac, N; Goutelle, S, 2014) |
| "Nicardipine and labetalol are two commonly used antihypertensives for treating elevated blood pressures in the setting of intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH)." | 3.79 | Effectiveness and safety of nicardipine and labetalol infusion for blood pressure management in patients with intracerebral and subarachnoid hemorrhage. ( Agarwal, S; Badjatia, N; Carpenter, AM; Claassen, J; Lantigua, H; Lee, K; Lesch, C; Li, M; Mayer, SA; Ortega-Gutierrez, S; Reccius, A; Schmidt, JM; Thomas, J, 2013) |
| " Continuous intravenous nicardipine (CIVN), prescribed for posttransplant hypertension, inhibits tacrolimus metabolism by cytochrome P450 (CYP) 3A4 and could lead to tacrolimus overexposure in patients genetically lacking the alternative pathway for tacrolimus metabolism, CYP3A5." | 3.78 | Risk of tacrolimus toxicity in CYP3A5 nonexpressors treated with intravenous nicardipine after kidney transplantation. ( Fukuda, T; Gardiner, R; Goebel, J; Hooper, DK; Kirby, CL; Logan, B; Roy-Chaudhury, A; Vinks, AA, 2012) |
| "American Heart Association/American Stroke Association guidelines for management of aneurysmal subarachnoid hemorrhage (aSAH) recommend blood pressure (BP) control, utilizing labetalol or nicardipine, but do not differentiate efficacy between the two agents." | 3.78 | Retrospective evaluation of nicardipine versus labetalol for blood pressure control in aneurysmal subarachnoid hemorrhage. ( Barletta, JF; DeShane, RS; Figueroa, BE; McAllen, KJ; Woloszyn, AV, 2012) |
| "An eight-year-old boy with Burkitt lymphoma developed severe macroglossia and angioedema when treated with nicardipine." | 3.77 | Angioedema associated with dihydropyridine calcium-channel blockers in a child with Burkitt lymphoma. ( Gordon, CJ; Hederman, AD; Herrington, B; Ostrenga, AR; Pierce, WA, 2011) |
| "The potent vasodilators nicardipine and prostaglandin E1 (PGE1) are useful for the treatment of systemic hypertension or pulmonary hypertension during aortic surgery." | 3.74 | The comparative effects of intravenous nicardipine and prostaglandin E1 on the cerebral pial arteriolar constriction seen after unclamping of an aortic cross-clamp in rabbits. ( Dohi, S; Iida, H; Iida, M; Kumazawa, M; Takenaka, M; Uchida, M, 2007) |
| "Nicardipine hydrochloride (Nic), a calcium channel antagonist, is used for the treatment of hypertension." | 3.74 | Induction of hepatic cytochrome P450 isoforms by nicardipine at therapeutic doses in spontaneously hypertensive rats. ( Degawa, M; Kasahara, T; Kinae, Y; Miyajima, S; Nemoto, K; Sekimoto, M; Souma, S, 2007) |
| "Evaluate the ease of use and tolerability of labetalol (L) and nicardipine (N) for hypertension management in patients with acute stroke." | 3.74 | A comparison of nicardipine and labetalol for acute hypertension management following stroke. ( Coplin, WM; Janisse, J; Liu-Deryke, X; Norris, G; Parker, D; Rhoney, DH, 2008) |
| "We encountered a 91-year-old woman with atrial fibrillation complicating bradycardia while she was receiving therapy with an L/N-type calcium channel blocker, cilnidipine, for hypertension, which is an unusual observation for the dihydropyridine class of calcium channel blockers." | 3.73 | Comparison of the direct negative dromotropic effect of a new calcium channel blocker, cilnidipine, with that of nicardipine. ( Ando, K; Hashimoto, K; Nakamura, Y; Satoh, Y; Sugiyama, A; Takahara, A, 2005) |
| " This study was designed to investigate the acute effects of local application of a SMF to neck or pelvic region under pharmacologically modulated BP; norepinephrine (NE)-induced hypertension as well as an L-type voltage-gated Ca(2+) channel blocker, nicardipine (NIC)-induced hypotension in conscious rabbits." | 3.73 | Effects of neck exposure to 5.5 mT static magnetic field on pharmacologically modulated blood pressure in conscious rabbits. ( Ohkubo, C; Okano, H, 2005) |
| "We observed a high rate of tolerability among patients with intracerebral hemorrhage who were treated with intravenous nicardipine using mean arterial pressure goals defined by American Heart Association guidelines within 24 hrs of symptom onset." | 3.73 | Treatment of acute hypertension in patients with intracerebral hemorrhage using American Heart Association guidelines. ( Ahmed, S; Divani, AA; Harris-Lane, P; Jacob, M; Kirmani, JF; Qureshi, AI; Zada, Y, 2006) |
| " Hypertension was treated in 12 patients (esmolol n = 6, urapidil n = 5, nicardipine)." | 3.73 | Improvement of donor myocardial function after treatment of autonomic storm during brain death. ( Audibert, G; Charpentier, C; Charretier, PA; Devaux, Y; Grégoire, H; Longrois, D; Mertes, PM; Perrier, JF; Seguin-Devaux, C, 2006) |
| "To describe the clinical course of a newborn (gestational age 38 wk, 6 d) administered intravenous nicardipine to control hypertension while on extracorporeal membrane oxygen (ECMO) support." | 3.72 | Nicardipine to control neonatal hypertension during extracorporeal membrane oxygen support. ( Campbell, M; Frey, BM; McBride, BF; White, CM, 2003) |
| "To examine the effect of intravenous nicardipine in the treatment of children with severe hypertension." | 3.71 | Intravenous nicardipine for treatment of severe hypertension in children. ( Brophy, PD; Bunchman, TE; Flynn, JT; Kershaw, DB; Mottes, TA; Smoyer, WE, 2001) |
| "In the present study, in order to elucidate the role of dihydropyridine (DHP)-sensitive calcium (Ca) channels in the regulation of neurotransmitter release in hypertension, we examined the effects of the DHP-sensitive Ca channel blocker nicardipine on norepinephrine (NE) release in blood vessels of spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto (WKY) rats." | 3.71 | Role of dihydropyridine-sensitive calcium channels in the regulation of norepinephrine release in hypertension. ( Masuyama, Y; Nishio, I; Tsuda, K; Tsuda, S, 2001) |
| " The purpose of the present study was to investigate the ventriculo-arterial coupling during hypertension, and the effects of nicardipine on this relationship in surgical patients using Ea/Ees and SW/MVO2 as indicators." | 3.70 | Effects of nicardipine on ventriculo-arterial coupling in humans. ( Kawahito, S; Kimura, H; Kitahata, H; Oshita, S; Park, YC; Sakabe, T; Tanaka, K, 1998) |
| "Nicardipine, a dihydropyridine type calcium channel blocker, was infused at two flow-rates into spontaneously hypertensive (SH) and control normotensive Wistar-Kyoto (WKY) rats (young, 6-week-old and adult, 23-week-old, n = 5) under pentobarbital anesthesia, to cause hypotension." | 3.70 | Changes of plasma L-arginine levels in spontaneously hypertensive rats under induced hypotension. ( Fukushima, T; Homma, H; Imai, K; Kasai, C; Matsunaga, H; Mori, T; Prados, P; Santa, T, 1999) |
| " Twenty-three patients with moderate essential hypertension were studied before and during acute (10 patients) and chronic (21 patients) treatment with a dihydropyridine calcium antagonist (nifedipine, nicardipine or felodipine) as monotherapy in a dose titrated to produce a fall in mean cuff pressure of at least 10%." | 3.70 | The effects of acute and chronic dihydropyridine calcium antagonist therapy on baroreflex sensitivity: a re-analysis using the sequence method. ( Jordan, PJ; Littler, WA; Stallard, TJ; Vaile, JC, 2000) |
| "Isradipine is an effective, orally administered agent for control of hypertension in children." | 3.70 | Initial experience with isradipine for the treatment of hypertension in children. ( Groshong, T; Strauser, LM; Tobias, JD, 2000) |
| "Transmitral flow velocities were measured by pulsed-Doppler echocardiography before and during infusion of nicardipine (1, 2 and 3 micrograms/kg per min) and diltiazem (5, 10 and 15 micrograms/kg per min) in seven patients with essential hypertension." | 3.69 | Effect of intravenous calcium antagonists on left ventricular diastolic function in hypertension: assessed by pulsed-Doppler echocardiogram. ( Dohi, Y; Kojima, M; Sato, K, 1995) |
| " Among these agents, diltiazem has been found to be sufficiently potent to control systemic hypertension but to have a less potent dilatory action on the cerebral vasculature in experimental animals." | 3.69 | Control of systemic hypertension with diltiazem, a calcium-antagonist, in patients with a mildly elevated intracranial pressure: a comparative study. ( Hirayama, T; Kano, T; Katayama, Y; Tsubokawa, T, 1994) |
| "An animal model having both hypertension and reduced renal function was produced by intraperitoneal injection of puromycin aminonucleoside (PAN) in spontaneously hypertensive rat (SHR)." | 3.69 | Effects of dihydropyridine Ca blockers on the renal function in nephrotic spontaneously hypertensive rat (SHR). ( Koike, H; Miyamoto, M; Oizumi, K, 1994) |
| "The effects of long-term treatment with sustained-release nicardipine (nicardipine SR) on left ventricular hypertrophy and function were studied." | 3.69 | Effects of long-term treatment with sustained-release nicardipine on left ventricular hypertrophy and function in patients with essential hypertension. ( Hiwada, K; Imamura, Y; Joh, T; Matsubara, W; Ochi, T; Sumimoto, T, 1994) |
| "This trial was designed to confirm the hypotensive action and safety of slow-release nicardipine, as a single drug or together with other hypotensive drugs, for the short-term treatment of mild-to-moderate hypertension, on a large case list of patients in 57 centers throughout Italy." | 3.69 | [Nationwide drug surveillance project on slow-release nicardipine in the short-term therapy of light/moderate arterial hypertension]. ( Benvenuti, C; Guerini Rocco, C; Trezzi, P, 1995) |
| " Intermittent injection of nicardipine was quite effective to control the hypertension during anesthesia." | 3.69 | [Anesthesia for cesarean section in a patient with intracranial A-V malformation]. ( Kawada, K; Kubota, M; Ogawa, H; Tamakawa, S; Terao, M, 1995) |
| "Arterial hypertension is frequent in liver transplant recipients on cyclosporine A (CsA)." | 3.69 | Nicardipine as antihypertensive therapy in liver transplant recipients: results of long-term use. ( Cherqui, D; Dhumeaux, D; Di Martino, V; Duvoux, C; Fagniez, PL; Lauzet, JY; Métreau, JM; Salvat, A, 1997) |
| " The influence of hypertension and treatment with the dihydropyridine-type Ca2+ antagonist, nicardipine, on the structure of the kidney was assessed in spontaneously hypertensive rats (SHR) of 12 weeks of age." | 3.69 | Influence of long-term treatment with the dihydropyridine-type calcium antagonist nicardipine on renal microanatomical changes in spontaneously hypertensive rats. ( Abbate, F; Amenta, F; Cavallotti, C; Ciriaco, E; Ferrante, F; Sabbatini, M, 1995) |
| "This study confirms the excellent efficacy of nicardipine in the management of postoperative hypertension, but underlines the risk of poor cardiac tolerance in patients after major surgery." | 3.69 | Intravenous nicardipine in the treatment of postoperative arterial hypertension. ( Berlot, G; Dereume, JP; Engelman, E; Khan, RJ; Preiser, JC; Vincent, JL, 1997) |
| " DESIGN OF STUDIES: Mean cerebral circulation parameters were studied in chronic stroke patients with hypertension and treated acutely or chronically (2 weeks) with nicardipine or nifedipine retard." | 3.68 | Effects of dihydropyridines on cerebral blood vessels. ( Hashimoto, H; Kuriyama, Y; Nagatsuka, K; Omae, T; Sawada, T, 1993) |
| "Seven patients scheduled for clipping of an aneurysm of the internal carotid artery after subarachnoid haemorrhage, were studied in order to evaluate the efficacy of a bolus injection of nicardipine (2 mg) in the treatment of intra-operative hypertension on the blood flow velocity of vessel near the aneurysm under isoflurane anaesthesia." | 3.68 | Effect of nicardipine on the blood flow velocity in the vessel near a cerebral aneurysm of the internal carotid artery during cerebral aneurysm surgery: its therapeutic use for intra-operative hypertension. ( Abe, K; Inagaki, Y; Iwanaga, H, 1993) |
| "Effects of Ca ion channel blockers, nicardipine, diltiazem and nifedipine on intraoperative hypertension were evaluated clinically in ninety surgical patients who received various surgical procedures under total intravenous anesthesia with droperidol, fentanyl and ketamine." | 3.68 | [Clinical study of total intravenous anesthesia with droperidol, fentanyl and ketamine--effects of nicardipine, diltiazem and nifedipine on intraoperative hypertension]. ( Hashimoto, Y; Hirota, K; Ishihara, H; Koh, H; Matsuki, A; Takagi, H, 1993) |
| "The present study was designed to investigate the effect of nicardipine administration upon systolic blood pressure (SBP) and cardiac hypertrophy in spontaneously hypertensive rats (SHR)." | 3.68 | Effect of nicardipine treatment upon cardiac hypertrophy in spontaneously hypertensive rats: a morphometric and ultrastructural study. ( Amenta, F; Bronzetti, E; Ciriaco, E; Felici, L; Ferrante, F, 1992) |
| "We studied the influence of nicardipine on renin-angiotensin (RA) system in twelve elderly patients, because the suppression of RA system, the decrease in reactivity of its feedback mechanism, and a high probability of arteriosclerosis and hypertension are well recognized in elderly patients." | 3.68 | [Influence of nicardipine on the renin-angiotensin system ina hypertensive crisis during operation in elderly patients]. ( Fukushima, T; Ishii, S; Kaneuchi, M; Katayama, H; Mizobuchi, S; Ochiai, Y; Takahashi, S; Tokaji, A, 1992) |
| "Haemodynamic changes in the carotid and brachial arteries produced by single doses of four anti-hypertensive drugs (nicardipine, enalapril, atenolol, and urapidil) have been studied in 12 patients with essential hypertension." | 3.68 | Changes in the haemodynamics of large arteries induced by single doses of nicardipine, enalapril, atenolol and urapidil. ( Arosio, E; Lechi, A; Pancera, P; Priante, F; Ribul, M; Talamini, G; Zannoni, M, 1992) |
| " Fifteen patients with mild pre-eclampsia were chronically treated with oral pindolol." | 3.68 | The effect of acute and chronic antihypertensive therapy on maternal and fetoplacental Doppler velocimetry. ( Bjornsson, S; Cameron, AD; Fairlie, FM; Mathers, A; Walker, JJ, 1992) |
| "The effects of the calcium antagonist nicardipine on the pressor response to mental arithmetic, cold pressor and exercise tests have been studied in fifteen patients with established mild to moderate essential hypertension." | 3.68 | Effect of nicardipine on haemodynamic response to stress in hypertension. ( Hashimoto, N; Kobayashi, K; Nakamura, S; Satoh, S; Takabatake, T; Yamada, Y; Yamamoto, Y, 1992) |
| "The authors evaluated the systemic and ocular hypotensive effects of nicardipine hydrochloride (Perdipine:NH) in 31 cases with acute hypertension (over 160/95 mmHg) during cataract surgery." | 3.68 | [Control of blood pressure by a calcium antagonist during cataract surgery]. ( Amemiya, T; Imai, M; Kato, Y; Sasaki, T, 1992) |
| "The authors examine the most recent findings on arterial hypertension with particular emphasis to morphological changes of the arterial wall and to the results of nicardipine treatment in spontaneous hypertensive rats (SHR)." | 3.68 | [The structural aspects of the pharmacological activity of calcium antagonists. A general profile and the results of a pilot study of nicardipine]. ( Beghé, F; Ghione, S; Rosa, A; Rosa, C; Wirth, AM, 1992) |
| "Various aspects of carbohydrate and lipid metabolism have been studied in two groups of patients with mild hypertension before and after six months of treatment with either nicardipine (n = 10) or metoprolol (n = 10)." | 3.68 | Comparison of the effects of nicardipine and metoprolol on lipid and glycidic metabolism in hypertensive subjects. ( Andriani, A; Bonfantino, MV; De Cesaris, R; Dentamaro, M; Filitti, V; Ranieri, G, 1991) |
| "Intraoperative hypertension over 160 mmHg systolic observed during total intravenous anesthesia with droperidol, fentanyl and ketamine was treated with intravenous nicardipine in 50 surgical patients." | 3.68 | [Clinical study on total intravenous anesthesia with droperidol, fentanyl and ketamine--4. Control of intraoperative hypertension with nicardipine]. ( Amano, N; Hirota, K; Ishihara, H; Koh, H; Kotani, N; Matsuki, A, 1991) |
| "The study aimed to assess the effects of nicardipine on the function and hemodynamic model of the left ventricle in 14 patients affected by slight to medium primary hypertension (8 male, 6 female, mean age 53 years) using M-B mode echocardiographic techniques." | 3.68 | [Effects of nicardipine on hemodynamic variables and on left ventricular function in hypertensive subjects]. ( Sarica, G, 1990) |
| "Fifty-six patients with severe hypertension were treated with intravenous nicardipine for infusion periods of eight to twenty-four hours." | 3.68 | Intravenous nicardipine: an effective new agent for the treatment of severe hypertension. ( Clifton, GG; Wallin, JD, 1990) |
| "The renal effects of oral maintenance doses of nicardipine 60-120 mg/day have been studied in 18 hypertensive patients with Type 2 (non-insulin-dependent) diabetes mellitus: 6 with normoalbuminuria (urinary albumin excretion rate, AER less than 20 micrograms." | 3.68 | Renal effects of nicardipine, a calcium antagonist, in hypertensive type 2 (non-insulin-dependent) diabetic patients with and without nephropathy. ( Baba, T; Murabayashi, S; Takebe, K; Tomiyama, T, 1990) |
| "Fourteen patients with vascular disease were studied to evaluate the efficacy of nicardipine hydrochloride as a hypotensive agent in the treatment of acute hypertension occurring during anaesthesia." | 3.67 | Haemodynamic effects of nicardipine hydrochloride. Studies during its use to control acute hypertension in anaesthetized patients. ( Furuya, H; Kishi, Y; Okumura, F, 1984) |
| "Nicardipine, a new calcium antagonist, was given to an insulin-treated diabetic patient with severe hypertension that had resisted ordinary antihypertensive treatment." | 3.67 | Effect of nicardipine in a hypertensive patient with diabetes mellitus. ( Miura, K; Sakata, S, 1984) |
| "Intra-arterial pressure, baroreflex sensitivity and the baroreflex set point were measured in eight patients with essential hypertension during a control period and then after acute treatment (2 h after a 30 mg oral dose) and after chronic treatment (at least 2 months) with nicardipine hydrochloride, a calcium channel antagonist." | 3.67 | Baroreflex setting and sensitivity after acute and chronic nicardipine therapy. ( Littler, WA; Watson, RD; Young, MA, 1984) |
| "Both the acute blood pressure lowering and renal effects of the calcium antagonist nicardipine and those after 1 week's treatment were investigated in 10 normotensive volunteers and in 10 patients with mild to moderate essential hypertension." | 3.67 | Antihypertensive and renal effects of nicardipine. ( Geyskes, GG; van Nistelrooy, AE; van Schaik, BA, 1984) |
| "The effects of the calcium-entry blocker nicardipine on brachial hemodynamics were studied in 22 patients (18 male, 4 female) with essential hypertension, who were treated with 20 mg tid for 1 year." | 3.67 | Effects of long-term nicardipine treatment on hemodynamics of large arteries in essential hypertension. ( Arcaro, G; Arosio, E; Lechi, A; Montesi, G; Pancera, P; Priante, F; Zannoni, M, 1989) |
| "The efficacy of nicardipine and nitroprusside in preventing poststernotomy hypertension was compared in two groups of 45 patients undergoing coronary artery surgery." | 3.67 | The efficacy of nicardipine and nitroprusside in preventing poststernotomy hypertension. ( Deen, L; Dijkhuis, JP; Koolen, JJ; Leyssius, AT; Meyne, NG; van Wezel, HB; Vergroesen, I; Visser, CA, 1989) |
| "Acute effects of coronary vasodilators (nifedipine, nicardipine, and nitroglycerin) on atrial natriuretic peptide (ANP) and the renin-angiotensin-aldosterone system were studied in normal subjects and patients with essential hypertension." | 3.67 | Effects of calcium antagonists and nitroglycerin on atrial natriuretic peptide in normal subjects and patients with essential hypertension. ( Aizawa, T; Ishihara, M; Iwasaki, T; Niwa, A; Shinoda, T; Yamada, T, 1989) |
| "The interference by two unrelated calcium entry blockers, nicardipine and verapamil, with the forearm vascular response to graded exogenous norepinephrine was evaluated in two groups (n = 6 each) of patients with uncomplicated hypertension." | 3.67 | Calcium entry blockade and alpha-adrenergic vascular reactivity in human beings: differences between nicardipine and verapamil. ( Pedrinelli, R; Salvetti, A; Taddei, S, 1989) |
| "To clarify the influence of Na balance on the hypotensive effect of calcium antagonists, the changes of blood pressure and humoral factors after a single oral administration of 40 mg nicardipine were evaluated in 15 subjects with essential hypertension under high, normal, and low Na regimens (mean 24 hour urinary Na excretion: 320 +/- 24, 147 +/- 7, 27 +/- 6 mEq, respectively)." | 3.67 | Effect of sodium intake on the hypotensive effect of calcium antagonists. ( Gomi, T; Ibukiyama, C; Ikeda, T; Sakurai, J; Toya, Y, 1989) |
| " Parameters measured included blood pressure, blood chemistry (serum creatinine, uric acid, blood urea nitrogen, blood glucose total cholesterol, and electrolytes), plasma renin activity, and plasma aldosterone concentration." | 3.67 | Effects of nicardipine on blood pressure and renal function in elderly hypertensive patients with renal dysfunction. ( Saruta, T, 1989) |
| "Calcium channel blockers such as nicardipine act as arterial vasodilators and are effective in the treatment of hypertension." | 3.67 | Fetal vascular responses to maternal nicardipine administration in the hypertensive ewe. ( Parisi, VM; Salinas, J; Stockmar, EJ, 1989) |
| "To investigate the relationship between cardiac hypertrophy associated with hypertension, and the alterations in myocardial lipid metabolism, nicardipine (160 mg/kg/day), hydralazine (40 mg/kg/day), and enalapril (30 mg/kg/day) were administered to spontaneously hypertensive rats from 20 to 24 weeks of age." | 3.67 | Fatty acid binding protein of cardiac muscle in spontaneously hypertensive rats: effect of hypertrophy and its regression. ( Fujii, S; Kawaguchi, H; Okamoto, H; Saito, H; Togashi, H; Yasuda, H, 1988) |
| "Changes in hemodynamic variables regulating systolic function were assessed by M-mode echocardiography, under 2D control, in 11 patients with primary uncomplicated hypertension treated with nicardipine (60 mg/daily)." | 3.67 | [Echocardiographic analysis of anatomical and functional changes in the left heart ventricle during antihypertensive treatment with nicardipine]. ( Buonissimo, S; Costantino, G; De Simone, G; Di Lorenzo, L; Ferrara, LA; Moccia, D; Soro, S, 1988) |
| "A prospective study of the hypotensive effects of nicardipine has been performed during 65 administrations of the drug in 6 children with malignant hypertension." | 3.67 | [Treatment of hypertensive attacks in children with nicardipine]. ( Buttet, C; Cochat, P; David, L; Floret, D; Malfroy, J, 1988) |
| "Eighteen patients with severe hypertension received treatment with intravenous nicardipine." | 3.67 | Intravenous nicardipine for the treatment of severe hypertension. ( Bienvenu, GS; Blanski, L; Clifton, GG; Cook, ME; Laddu, A; Langford, H; Turlapaty, P; Wallin, JD, 1988) |
| "The effects of a calcium antagonist [Nicardipine hydrochloride (NH)] on the prostaglandin [prostaglandin E2 (PGE2), and 6-keto-prostaglandin F1 alpha (6-keto-PGF1 alpha)] and thromboxane B2 levels in the blood and urine were examined in 6 patients with essential hypertension following intravenous infusion of NH for 120 minutes." | 3.67 | Effects of intravenous administration of a calcium antagonist on prostaglandins and thromboxane in plasma and urine in humans. ( Fukuda, N; Hatano, M; Honda, M; Izumi, Y; Manabe, R; Minato, M; Watanabe, M, 1986) |
| "We evaluated the immediate hemodynamic response to nicardipine, administered as an intravenous bolus and 30-minute sustaining infusion, in 10 patients with systemic hypertension (HTN) and 10 patients with chronic congestive heart failure (CHF)." | 3.67 | Influence of baseline hemodynamic status and sympathetic activity on the response to nicardipine, a new dihydropyridine, in patients with hypertension or chronic congestive heart failure. ( Cody, RJ; Kubo, SH; Ryman, KS; Shaknovich, A, 1987) |
| "In 10 patients with moderate to severe hypertension, the hemodynamic effects of ergometric exercise and nicardipine, a dihydropyridine calcium channel antagonist, were characterized under basal conditions and after 1 week of therapy." | 3.67 | Systemic and pulmonary hemodynamic responses to nicardipine during graded ergometric exercise in patients with moderate to severe essential hypertension. ( Cody, RJ; Kubo, SH; Laragh, JH; Ryman, KS; Shaknovich, A, 1987) |
| "Cardiovascular, baroreflex and humoral responses were evaluated in 8 patients with essential hypertension during a control period and then after oral treatment for 5 days with nicardipine hydrochloride 60 mg/d, a calcium channel antagonist." | 3.67 | Cardiovascular, baroreflex and humoral responses in hypertensive patients during nicardipine therapy. ( Biggi, A; Coruzzi, P; Musiari, L; Novarini, A; Ravanetti, C, 1985) |
| "This study was designed to evaluate the efficacy of oral nicardipine in 91 patients with uncomplicated essential hypertension over a period of 12 months." | 3.67 | A study of the long-term efficacy and tolerability of oral nicardipine in hypertensive patients. ( Frais, MA; Jackson, N; Lee, P; Reynolds, G; Silke, B; Taylor, SH; Verma, SP, 1985) |
| "Eight untreated patients with essential hypertension (average casual blood pressure 180/110 +/- 27/12 mm Hg) were studied following control, acute (a single oral dose of 30 mg nicardipine hydrochloride), and chronic (2 months nicardipine oral therapy) treatment periods." | 3.67 | The effect of nicardipine on blood pressure, its variability and reflex cardiac control. ( Littler, WA; Young, MA, 1985) |
| "The effect of nicardipine on experimental hyperlipemia induced by a 1% cholesterol diet in spontaneously hypertensive rats (SHR) was investigated by the change of hemodynamics and the determination of lipid contents of the serum, liver, heart and aorta." | 3.67 | [Effect of nicardipine on cholesterol-fed S.H.R]. ( Kawashima, I; Nakayama, S; Ohba, T; Sakamoto, K; Tonooka, M; Yasuhara, H, 1985) |
| "The forearm vascular resistance (FVR) following intra-arterial infusions of the calcium influx inhibitors nicardipine and verapamil and sodium nitroprusside was compared to that following 10 min arterial occlusion in 10 normotensive (NT) individuals aged 45 +/- 12 years, 12 patients with mild essential hypertension (EH) aged 42 +/- 14 years and 11 patients with moderate EH aged 49 +/- 11 years." | 3.66 | Calcium influx mediated vasoconstriction: studies in patients with mild and moderate essential hypertension. ( Bolli, P; Bühler, FR; Hulthén, UL, 1983) |
| "We have assessed the potential antihypertensive effect of a new slow channel blocker, nicardipine, in a group of patients with essential hypertension." | 3.66 | The effect of a new calcium channel blocker nicardipine on 24-hour ambulatory blood pressure and the pressor response to isometric and dynamic exercise. ( Hornung, RS; Jones, RI; Raftery, EB; Sonecha, T, 1983) |
| " Initial dosing with nicardipine lowered acute diastolic BP than labetalol (least square mean difference (labetalol-nicardipine)=5." | 3.11 | Initial antihypertensive agent effects on acute blood pressure after intracerebral haemorrhage. ( Behymer, TP; Bettin, M; Christianson, T; Coleman, ER; Divani, A; Flaherty, ML; Gilkerson, LA; James, ML; King, NKK; Krishnamoorthy, V; Langefeld, CD; McCauley, JL; Ng, Y; Qi, W; Shah, S; Testai, FD; Walsh, KB; Woo, D, 2022) |
| "This is a substudy of the multicenter safety and efficacy Evaluation of intravenous Cardene (nicardipine) and Labetalol Use in the Emergency department (CLUE) trial that randomized patients to Food and Drug Administration-recommended intravenous dosing of nicardipine or labetalol to reach a physician predefined systolic BP (SBP) and target range (TR) of ±20 mm Hg within 30 minutes." | 2.79 | Impact of initial blood pressure on antihypertensive response in patients with acute hypertension. ( Farias, S; Gonzalez, M; Levy, PD; Peacock, WF, 2014) |
| "Clevidipine is a novel, rapidly acting dihydropyridine L-type calcium channel blocker with an ultrashort half-life that decreases arterial blood pressure (BP)." | 2.73 | The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients. ( Aronson, S; Cheung, AT; Dyke, CM; Kereiakes, DJ; Levy, JH; Lumb, PD; Newman, MF; Stierer, KA, 2008) |
| "Nicardipine was effective in 87% of the patients (with intravenous beta blockers in 4 patients), with a 19." | 2.73 | Management of hypertensive emergencies in acute brain disease: evaluation of the treatment effects of intravenous nicardipine on cerebral oxygenation. ( Narotam, PK; Nathoo, N; Puri, V; Roberts, JM; Taylon, C; Vora, Y, 2008) |
| "Nicardipine and clonidine were compared with placebo in a double-blind, randomized, three-way cross-over controlled study after a 2-week placebo run-in period." | 2.70 | Effects of nicardipine and clonidine on cognitive functions and electroencephalography in hypertensive patients. ( Allain, H; Bentué-Ferrer, D; Breton, S; Cimarosti, I; Denolle, T; Gandon, JM; Merienne, M; Ouatara, B; Sassano, P, 2002) |
| " However, the total incidence of adverse reactions, including non-CV events and unfavorable BP changes, was 31 cases (15." | 2.70 | Tolerability and safety of a calcium channel blocker in comparison with a diuretic in the treatment of elderly patients with hypertension: secondary analysis of the NICS-EH. ( Abe, K; Fujishima, M; Fukiyama, K; Hiwada, K; Iimura, O; Ishii, M; Kuramoto, K; Kuwajima, I; Ogihara, T; Saruta, T, 2001) |
| "The initial nicardipine dosage was 0." | 2.69 | Intravenous nicardipine as a first-line antihypertensive drug in neonates. ( Debuche-Benouachkou, V; Germain, JF; Gouyon, JB; Milou, C; Semama, DS, 2000) |
| ") are bioequivalent at the daily dosage used in the study." | 2.68 | Comparison between a bid and a tid regimen: improved compliance with no improved antihypertensive effect. The EOL Research Group. ( Alamercery, Y; Benghozi, R; Boissel, JP; Ducruet, T; Meillard, O; Perrin-Fayolle, E; Sassano, P, 1996) |
| "Renal hemodynamics was investigated in 25 patients." | 2.68 | Effects of benazepril and nicardipine on microalbuminuria in normotensive and hypertensive patients with diabetes. ( Andriani, A; Bertocchi, F; Bonfantino, MV; Cavallo, A; De Cesaris, R; Lamontanara, G; Ranieri, G, 1996) |
| "Hypertension is often related to metabolic disorders, such as android obesity, glucose intolerance, dyslipidemia, and hyperinsulinism (X syndrome)." | 2.67 | Comparison of the effects of captopril and nicardipine on insulin sensitivity and thrombotic profile in patients with hypertension and android obesity. CaptISM Study Group. Captopril Insulin Sensitivity Multicenter Study Group. ( Boucher, L; Cozic, JA; Gorlier, R; Huin, P; Pettenuzzo-Mollo, M; Provendier, O; Raccah, D; Sicard, J; Vague, P, 1994) |
| "The aim of this study was to evaluate the effects of nicardipine, at the dosage of 80 mg/day in two administrations, on blood pressure, intimal-media thickness of the common carotid artery and on arterial distensibility after 6 months of therapy." | 2.67 | Effects of nicardipine on intimal-medial thickness and arterial distensibility in hypertensive patients. Preliminary results after 6 months. ( Cicatiello, AM; Giordano, G; Guarini, P; Iovino, L; Messina, V; Tagliamonte, MR; Tedeschi, C, 1993) |
| "Nicardipine treatment significantly decreased systolic and diastolic blood pressure and increased plasma noradrenaline levels measured at supine rest." | 2.67 | [Nicardipine attenuates the sympathetic reflex of orthostatism: do dihydropyridine-sensitive calcium channels regulate noradrenaline release?]. ( Cherchi, A; Lai, L; Longu, G; Manca, MR; Mercuro, G; Rossetti, ZL; Ruscazio, M, 1992) |
| "To evaluate the effects of short- and long-term administration of calcium (Ca) entry blockers on cardiovascular responses to cigarette smoking, 28 normotensive and 26 hypertensive smokers were studied." | 2.67 | Effects of calcium channel blockers on cardiovascular responses to smoking in normotensive and hypertensive smokers. ( Corradi, L; Fogari, R; Malamani, GD; Zoppi, A, 1992) |
| "Nicardipine treatment significantly reduced blood pressures both in the supine and standing positions (p < 0." | 2.67 | Dose requirement and effect of nicardipine on lipid profile in mild to moderate essential hypertensives. ( Christina, P; Kamsiah, J; Maheendran, K; Tariq, AR, 1992) |
| "Hypertension was significantly better controlled in patients treated with nicardipine infusion compared with placebo (83% vs." | 2.67 | Nicardipine infusion for postoperative hypertension after surgery of the head and neck. ( Alicea, M; Goldberg, JS; Greenstein, R; Halpern, NA; Krakoff, LR; Neely, C; Sladen, RN; Wood, M, 1990) |
| "Nicardipine (80 mg/day) was given orally for 12 weeks and no dietary restrictions were imposed." | 2.67 | Efficacy of nicardipine slow release (SR) on hypertension, potassium balance and plasma aldosterone in idiopathic aldosteronism. ( Bisbocci, D; Chiandussi, L; Pinna, G; Piras, D; Rabbia, F; Veglio, F, 1990) |
| " The usefulness of intravenous nicardipine for postoperative hypertension was demonstrated in this study by: (1) the rapid control of blood pressure, (2) its continued efficacy during maintenance, and (3) little need to adjust dosage to control blood pressure." | 2.67 | Nicardipine versus placebo for the treatment of postoperative hypertension. ( Clark, S; Goldberg, ME; Joseph, J; Maguire, D; Moritz, H; Seltzer, JL; Turlapaty, P, 1990) |
| "Both drugs were effective in the treatment of hypertension." | 2.67 | Nicardipine and propranolol in the treatment of hypertension: similar antihypertensive but dissimilar hemodynamic actions. ( Featherston, W; Gonzalez, DG; Kaplan, NM; Lugo, C; Ralakis, J; Ram, CV, 1990) |
| " Two weeks of combined treatment with nicardipine and enalapril significantly reduced the predosing blood pressure, 12 h after the last dose of nicardipine (158/96 as compared with 172/106 with placebo), and there were further significant reductions in blood pressure during the subsequent dosage interval." | 2.66 | An evaluation of the pharmacodynamics and pharmacokinetics of nicardipine combined with enalapril in essential hypertension. ( Donnelly, R; Elliott, HL; Meredith, PA; Reid, JL, 1987) |
| "Nicardipine was well tolerated; orthostatic hypotension was not observed and there was no change in heart rate." | 2.66 | Nicardipine in elderly patients with hypertension: a review of experience in France. ( Bouchacourt, P; Forette, F; Henry, JF; Hervy, MP; McClaran, J, 1989) |
| "Nicardipine is an investigational dihydropyridine calcium channel blocking agent." | 2.66 | Nicardipine and hydrochlorothiazide in essential hypertension. ( Brown, R; Conrad, KA; Fagan, TC; Freedman, D; Lessem, J; Michelson, E; Montijo, M; Schnaper, H; Smolens, P, 1989) |
| " The absolute decrements peaked 4 h after dosing (-18." | 2.66 | Antihypertensive effect of slow-release nicardipine. A placebo-controlled cross-over study. ( Caiazza, A; Cardellino, G; Del Prato, C; Errico, M; Freda, M; Ghisoni, F; Innocenti, PF; Pesenti, M; Ponzanelli, F; Salvetti, A, 1989) |
| "Treatment with amiloride + HCTZ led to elevations in serum levels of cholesterol, uric acid and urea, which were maintained at one year, whilst no abnormalities in blood biochemistry were seen in patients treated with nicardipine." | 2.66 | A randomised comparative trial of nicardipine versus amiloride and hydrochlorothiazide in mild to moderate hypertension. A report from the General Practitioner Hypertension Study Group. ( Bradley, I; Davis, A; Ganvir, P; Gostick, NK; Hopwood, AM; MacKay, D; Mayhew, SR; Mukerji, D; Shepherd, F, 1989) |
| "Nicardipine-based treatment reduced systolic and diastolic blood pressures to similar levels independently of the age of the patients." | 2.66 | Antihypertensive efficacy of nicardipine-based treatment in patients of different age and in patients with isolated systolic hypertension. ( Leonetti, G; Zanchetti, A, 1988) |
| "Nicardipine was given intravenously as a 2 mg bolus, followed by an infusion at a rate designed to lower the supine diastolic blood pressure at least 10 mm Hg; then oral captopril, 50 mg, or placebo was given." | 2.66 | Antihypertensive effects of parenteral nicardipine alone and in combination with captopril. ( Conrad, KA; Davis, TP; Fagan, TC; Johnson, DG; Mayshar, P, 1987) |
| "Nicardipine appears to blunt the secretion of aldosterone responding to an increased PRA possibly through its calcium-antagonizing action." | 2.66 | Multiple oral doses of nicardipine, a calcium-entry blocker: effects on renal function, plasma renin activity, and aldosterone concentration in mild-to-moderate essential hypertension. ( Aoyagi, K; Baba, T; Ishizaki, T; Murabayashi, S; Takebe, K; Tamasawa, N, 1987) |
| "Domperidone pretreatment prevented the GFR increase induced by nicardipine and increased the noradrenaline response (+107%), but did not change the other actions of nicardipine." | 2.66 | Haemodynamic (systemic and renal) and humoral interactions between nicardipine and domperidone in hypertensives. ( Lucarini, AR; Salvetti, A, 1987) |
| "We conducted a randomized placebo-controlled double-blind study in 40 hypertensive subjects to assess the antihypertensive effect of a new galenic form of nicardipine administered at a dosage of 50 mg twice daily for 3 weeks." | 2.66 | Evaluation of slow release nicardipine in essential hypertension by casual and ambulatory blood pressure measurements. Effects of acute versus chronic administration. ( Bellet, M; Chatellier, G; Corvol, P; Ménard, J; Pagny, JY, 1987) |
| "Nicardipine was tolerated very well, and orthostatic hypotension was never observed." | 2.66 | Effect of nicardipine in elderly hypertensive patients. ( Bellet, M; Bouchacourt, P; Forette, F; Guerret, M; Henry, JF; Hervy, MP; Poyard-Salmeron, C, 1985) |
| "Nicardipine was given three times a day (mean dose: 69." | 2.65 | [Treatment of arterial hypertension in the aged with a calcium antagonist: nicardipine]. ( Bellet, M; Bouchacourt, P; Forette, F; Henry, JF; Hervy, MP; Poyard-Salmeron, C, 1984) |
| "Nicardipine has been studied or recommended for management of hypertension in many neurovascular settings (ischemic stroke, intracerebral hemorrhage, craniotomy, and spinal surgery), for vasospasm in aneurysmal subarachnoid hemorrhage, and in acute traumatic brain injury." | 2.45 | Use of injectable nicardipine for neurovascular indications. ( Reddy, P; Yeh, YC, 2009) |
| "Perioperative hypertension is commonly encountered in patients that undergo surgery." | 2.44 | Perioperative hypertension management. ( Marik, PE; Varon, J, 2008) |
| "Nicardipine is a water soluble calcium channel antagonist, with predominantly vasodilatory actions." | 2.43 | Intravenous nicardipine: its use in the short-term treatment of hypertension and various other indications. ( Curran, MP; Keating, GM; Robinson, DM, 2006) |
| "Hypertension that complicates preeclampsia in pregnancy is a disorder that requires special consideration in both prevention and pharmacologic treatment." | 2.43 | Pathophysiology and medical management of systemic hypertension in preeclampsia. ( Frishman, WH; Schlocker, SJ; Tejani, N; Veresh, M, 2006) |
| "While nitroprusside is commonly used to treat severe hypertension, it is an extremely toxic drug that should only be used in rare circumstances." | 2.41 | The diagnosis and management of hypertensive crises. ( Marik, PE; Varon, J, 2000) |
| "Nicardipine is a calcium antagonist belonging to the dihydropyridine group of molecules." | 2.41 | [Intravenous nicardipine: a new calcium antagonist for perioperative use]. ( Barcina Sánchez, M; Muñoz Alameda, LE, 2001) |
| "Nicardipine is a second generation dihydropyridine-type Ca2+ antagonist with high vascular selectivity and strong cerebral and coronary vasodilatory activity." | 2.39 | Nicardipine and treatment of cerebrovascular diseases with particular reference to hypertension-related disorders. ( Amenta, F; Sabbatini, M; Strocchi, P, 1995) |
| "Nicardipine has no clinically significant negative inotropic effect." | 2.39 | Concomitant diseases in elderly hypertensives: the position of nicardipine. ( Zannad, F, 1996) |
| "Nicardipine has a short duration factor, is easily titratable and is as effective as nitroglycerin or nitroprusside in the control of hypertension." | 2.38 | Clinical considerations for the use of intravenous nicardipine in the treatment of postoperative hypertension. ( Kaplan, JA, 1990) |
| "Moyamoya disease (MMD) and posterior reversible encephalopathy syndrome (PRES) share similar pathophysiological characteristics of endothelial dysfunction and impaired cerebral autoregulation." | 1.62 | Posterior reversible encephalopathy syndrome (PRES) in a patient with moyamoya disease: A case report. ( Chou, PS; Teng, CH; Wu, MN; Yang, IH, 2021) |
| "Perioperative hypertension is a common occurrence in the neurosurgical population, where 60% to 90% of the patients require treatment for blood pressure (BP) control." | 1.56 | Clevidipine use after first-line treatment failure for perioperative hypertension in neurosurgical patients: A single-center experience. ( Bergese, SD; Borrell-Vega, J; Palettas, M; Uribe, AA, 2020) |
| "The worldwide incidence of coronavirus disease 2019 (COVID-19) infection is rapidly increasing, but there exists limited information on coronavirus disease 2019 in pregnancy." | 1.56 | Coronavirus disease 2019 in pregnancy: early lessons. ( Baptiste, C; Breslin, N; D'Alton, M; Fuchs, K; Goffman, D; Gyamfi-Bannerman, C; Miller, R, 2020) |
| " Demographic, operative, laboratory, and postoperative data were collected for adverse effect analysis and outcomes comparisons between infants aged younger than 6 months (group 1) and older than 6 months (group 2)." | 1.48 | Use of Nicardipine After Cardiac Operations Is Safe in Children Regardless of Age. ( Buck, M; Gangemi, J; Kelly, J; Mistry, M; Stone, ML; Vergales, J, 2018) |
| "Infection and sepsis has been reported as a possible cause for this disorder." | 1.48 | A case of posterior reversible encephalopathy syndrome associated with sepsis. ( Garner, O; Iardino, A; Ramirez, A, 2018) |
| "A history of hypertension is a known risk factor for delirium in patients in intensive care units, but the effect of antihypertensive agents on delirium development is unclear." | 1.48 | Relationship between the administration of nicardipine hydrochloride and the development of delirium in patients on mechanical ventilation. ( Chuma, M; Goda, M; Hamano, H; Horinouchi, Y; Imai, T; Imanishi, M; Ishizawa, K; Kayano, M; Kitamura, Y; Kondo, Y; Kouno, Y; Koyama, T; Mitsui, M; Niimura, T; Okada, N; Sendo, T; Takechi, K; Ujike, Y; Yanagawa, H; Zamami, Y, 2018) |
| "The systolic blood pressure, ratio of cardiac arrest, and Fisher classification values of the patients in the Scene group were significantly greater than those in the Interhospital group." | 1.46 | A comparison between evacuation from the scene and interhospital transportation using a helicopter for subarachnoid hemorrhage. ( Ishikawa, K; Jitsuiki, K; Nakao, Y; Ohsaka, H; Omori, K; Takeuchi, I; Yamamoto, T; Yanagawa, Y; Yoshizawa, T, 2017) |
| "We present a case of neurogenic stunned myocardium, discovered intraoperatively after anesthetic induction, in a patient who presented to our operating room with a recent intraparenchymal hemorrhage." | 1.43 | Prolonged Cardiac Dysfunction After Intraparenchymal Hemorrhage and Neurogenic Stunned Myocardium. ( Krishnamoorthy, V; Sharma, D; Vavilala, MS; Wilson, T, 2016) |
| "Tacrolimus is a calcineurin inhibitor primarily metabolized by CYP3A4 and secondarily by CYP3A5." | 1.42 | Involvement of CYP 3A5 In the Interaction Between Tacrolimus and Nicardipine: A Case Report. ( Gaies, E; Klouz, A; Lakhal, M; Salouage, I; Sassi, MB; Trabelsi, S, 2015) |
| "Hypertension is the leading cause." | 1.38 | [Medical therapy for intracranial hemorrhage: update blood pressure management for prevention and acute treatment]. ( Koga, M; Toyoda, K, 2012) |
| " Aside from patients presenting with ischemic or traumatic brain injury, labetalol was safe to use in this population for hypertensive emergencies and had a satisfactory adverse effect profile." | 1.37 | Safety and efficacy of intravenous labetalol for hypertensive crisis in infants and small children. ( Feig, DI; Moffett, BS; Mott, AR; Thomas, CA; Wagner, JL, 2011) |
| "Hypokalemia was not clearly recognized preoperatively but became obvious within 3 h of general anesthesia with epidural blockade." | 1.37 | Ectopic ACTH syndrome revealed as severe hypokalemia and persistent hypertension during the perioperative period: a case report. ( Fukuda, K; Hirota, K; Kishimoto, S; Segawa, H, 2011) |
| "CIVN, used to treat post-KTX hypertension, may inhibit TAC metabolism resulting in overexposure and potential toxicity." | 1.37 | Interaction between tacrolimus and intravenous nicardipine in the treatment of post-kidney transplant hypertension at pediatric hospitals. ( Carle, AC; Goebel, J; Hooper, DK; Schuchter, J, 2011) |
| "Efforts to increase the awareness and treatment of hypertension in the population at large may lower the incidence of hypertensive crisis and its complications." | 1.37 | Dutch guideline for the management of hypertensive crisis -- 2010 revision. ( Beutler, JJ; de Gooijer, A; Gaillard, CA; Kroon, AA; van den Born, BJ; van den Meiracker, AH, 2011) |
| "Reversible posterior leukoencephalopathy syndrome (RPLS) is a recently identified clinical and radiologic entity." | 1.36 | A case of reversible posterior leukoencephalopathy syndrome in a patient on peritoneal dialysis. ( Furusu, A; Hirose, M; Kitamura, M; Kohno, S; Nishino, T; Obata, Y; Uramatsu, T, 2010) |
| "We report a case of Cushing's disease revealed by recurrent rupture of Achilles tendon." | 1.35 | Spontaneous rupture of Achilles tendon and Cushing's disease. Case report. ( Batisse, M; Delorme, JP; Desbiez, F; Somda, F; Tauveron, I; Thieblot, P, 2008) |
| "Clevidipine is an arterial, selective, dihydropyridine calcium channel blocker with an ultrashort half-life." | 1.35 | Clevidipine in the treatment of perioperative hypertension: assessing safety events in the ECLIPSE trials. ( Aronson, S, 2009) |
| "Azelnidipine is a new dihydropyridine calcium channel blocker that causes minimal stimulation of the sympathetic nervous system despite its significant depressor effect." | 1.34 | Azelnidipine attenuates cardiovascular and sympathetic responses to air-jet stress in genetically hypertensive rats. ( Nakamoto, M; Ohya, Y; Sakima, A; Takishita, S; Yamazato, M, 2007) |
| "Treatment with nicardipine countered microanatomical changes occurring in SHR, whereas hydralazine displayed a less pronounced effect." | 1.32 | Treatment with nicardipine protects brain in an animal model of hypertension-induced damage. ( Amenta, F; Tomassoni, D, 2004) |
| "Pretreatment with candesartan for 3 days or nicardipine for 28 days was ineffective." | 1.31 | Protection against ischemia and improvement of cerebral blood flow in genetically hypertensive rats by chronic pretreatment with an angiotensin II AT1 antagonist. ( Bregonzio, C; Falcón-Neri, A; Ito, T; Saavedra, JM; Terrón, JA; Yamakawa, H, 2002) |
| "The emergencies are defined by the gravity of acute visceral failures." | 1.31 | [Hypertension emergencies]. ( Baccar, H; Bezdah, L; Kasri, R; Ouechtati, W, 2000) |
| "In the drug-untreated group, recurrence of stroke was repeated, deterioration and amelioration of neurological deficits (ND) were repeated, and histological examination and measurement of regional blood flow (rBF) using nonradioactive colored microspheres performed at the end of treatment revealed severe damages and significantly decreased rBF in brain and kidney, respectively." | 1.30 | Therapeutic effects of a calcium antagonist, lacidipine, on stroke-prone spontaneously hypertensive rats with cerebrovascular lesions. ( Funato, H; Uemura, A; Watanabe, M, 1999) |
| " Dosing regimens and possible applications in paediatric anaesthesia are discussed." | 1.29 | Nicardipine: perioperative applications in children. ( Deshpande, JK; Lowe, S; Tobias, JD, 1995) |
| " Co-administration with propranolol markedly decreased the heart rate, but little affected the heart weight, suggesting changes in the heart rate during the long-term administration of KW-3049 did not largely affect cardiac hypertrophy." | 1.29 | Effect of the new calcium antagonist (+/-)-(R*)-3-[(R*)-1-benzyl-3- piperidyl] methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5- pyridinedicarboxylate hydrochloride (KW-3049) on cardiac hypertrophy in spontaneously hypertensive rats. ( Deguchi, T; Hara, T; Hattori, O; Kato, Y; Saijyo, T; Suzuki, K; Tanaka, H, 1993) |
| "Hypertension is a primary aggravating factor in cerebral infarction." | 1.29 | M1 receptors in blood pressure-controlled ischemic spontaneously hypertensive rats. ( Asanuma, M; Hirata, H; Kondo, Y; Ogawa, N; Tanaka, K, 1995) |
| " These results suggested that AJ-2615 has potential as a long-acting (once daily dosage regimen) antihypertensive drug without causing a steep blood pressure fall and tachycardia." | 1.29 | Antihypertensive effects of AJ-2615, a new calcium antagonist with alpha 1-adrenergic blocking activity in experimental hypertensive animals. ( Fukuya, F; Hosoki, K; Ikeno, A; Karasawa, T; Minato, H; Nose, I; Takeyama, K, 1993) |
| "Treatment with nicardipine significantly reduced blood pressure and albuminuria and increased urinary sodium excretion." | 1.29 | Protective effect of nicardipine treatment on renal microanatomical changes in spontaneously hypertensive rats. ( Abbate, F; Amenta, F; Ciriaco, E; Ferrante, F; Polidori, C, 1994) |
| "To study the effect of long-term administration of NKY-722 and nicardipine on renal dysfunction and morphological changes in the kidneys and arteries in Dahl salt-sensitive (Dahl-S) rats." | 1.29 | Protective effect of the calcium antagonist NKY-722 against renal and arterial injuries in Dahl salt-sensitive rats. ( Hashizume, Y; Ishimitsu, T; Kanda, M; Nakamura, S; Shimaji, H; Shirahase, H; Uehara, Y; Wada, K, 1994) |
| "Nicardipine was used as hypotensive drug." | 1.29 | [Application of the concept of fuzzy logistic controller for treatment of hypertension during anesthesia]. ( Hiraoka, I; Kaieda, R; Murakawa, T; Nakakimura, K; Oshita, S; Tamura, H, 1993) |
| "Nicardipine was well tolerated and induced a significant decrease (p < 0." | 1.29 | Effect of nicardipine treatment on carbohydrate and lipoprotein metabolism in patients with hypertension. ( Chen, LM; Chu, NF; Fuh, MM; Shen, DC; Sheu, WH; Wang, DJ, 1993) |
| "Nicardipine is an intravenously administered dihydropyridine calcium channel antagonist whose primary physiological action includes vasodilatation." | 1.29 | Nicardipine to control mean arterial pressure during extracorporeal membrane oxygenation. ( Lynch, A; Pietsch, JB; Tobias, JD, 1996) |
| "Treatment with nicardipine significantly reduced systolic pressure in the SHR." | 1.29 | Vascular and neuronal hypertensive brain damage: protective effect of treatment with nicardipine. ( Amenta, F; Sabbatini, M; Strocchi, P, 1996) |
| "3-3 mg/kg), dose-response curves of the antihypertensive effect did not change and body weight gain was equal to that of the vehicle-treated group." | 1.28 | Antihypertensive effects of MPC-1304, a novel calcium antagonist, in experimental hypertensive rats and dogs. ( Haruno, A; Kanda, A; Miyake, H; Nagasaka, M, 1992) |
| " An iv Fat Tolerance Test (FTT) was also performed in 8 patients following placebo, treatment with acute nicardipine 20 mg and chronic administration of nicardipine SR." | 1.28 | Evaluation of lipid metabolism during antihypertensive treatment with nicardipine sr. ( Ferrara, LA; Mancini, M; Marotta, T; Pasanisi, F; Russo, O, 1992) |
| "Nicardipine was administered in a 1." | 1.28 | Central hypotensive effects of nicardipine in conscious freely moving spontaneously hypertensive rat. ( Brisac, AM; Champeroux, P; Lacolley, P; Laurent, S; Safar, M, 1991) |
| "In 43 patients suffering from bronchial asthma, the data on patients with normal and high systemic arterial pressure were correlated on the basis of studying external respiratory function and pulmonary circulation." | 1.28 | [The characteristics of the lung microcirculation and external respiratory function in bronchial asthma patients with systemic arterial hypertension]. ( Amosov, VI; Iartseva, EE; Sinitsyna, TM; Zhdanov, VF, 1991) |
| "Additional factors have been found, ie orthostatic hypotension whatever its mechanism, and association with diuretics, with or without hyponatremia." | 1.28 | Dizziness in the elderly and calcium channel antagonists. ( Hugues, FC; Le Jeunne, C; Munera, Y; Ozanne, H, 1991) |
| " It was administered for 22 days and the average daily dosage was 187mg." | 1.28 | [A case presenting a severe paralytic ileus during the continuous intravenous injection of nicardipine hydrochloride]. ( Honmou, O; Kurokawa, Y; Ohta, K; Uede, T, 1991) |
| " Chronic administration of YM-09730-5 (3 mg/kg) reduced the severity of glomerular lesions in the kidney and vasculitis in the mesenteric artery." | 1.28 | Antihypertensive and diuretic effects of YM-09730-5, a new calcium antagonist, in stroke-prone spontaneously hypertensive rats. ( Fujimoto, K; Inagaki, O; Kawashima, K; Oohata, H; Suzuki, T; Toda, H, 1991) |
| "nicardipine has urged us to prove this drug in the treatment of hypertensive attacks (SAP greater than or equal to 210 mmHg and/or DAP greater than or equal to 110 mmHg)." | 1.28 | [Effects of i.v. nicardipine in the treatment of hypertensive crisis]. ( Bolognesi, R; Conti, M; Manca, C; Straneo, U; Tsialtas, D, 1990) |
| "Nicardipine is an investigational dihydropyridine calcium-channel blocker." | 1.28 | Nicardipine in severe hypertension: oral therapy following intravenous treatment. ( Bienvenu, GS; Clifton, GG; Cook, E; Laddu, A; Turlapaty, P; Wallin, JD, 1990) |
| " Nicardipine in combination with atenolol or clonidine most effectively lowered blood pressure." | 1.28 | Nicardipine in combination with other antihypertensive drugs: calcium antagonist and prazosin have no additive antihypertensive effect? ( Jounela, AJ; Juustila, H; Kanniainen, E; Lilja, M; Pasanen, A, 1990) |
| " Further, the decrease of the vascular tone induced by long-term administration of the angiotensin converting enzyme inhibitor may be due to a reduction of increased [Ca2+]i in SHR." | 1.28 | Cytosolic free calcium of aorta in hypertensive rats. Chronic inhibition of angiotensin converting enzyme. ( Ikeda, M; Karaki, H; Koike, H; Ozaki, H; Sada, T; Sato, K, 1990) |
| " Dosage of calcium and phosphate, Na, K, aldosterone, in blood and urine and PTH and PRA in blood had been effectuated." | 1.28 | [Calcium intestinal absorption in normotensive and essential hypertensive subjects before and after nicardipine]. ( Carre, A; Debrueres, S; Fouquoire, B; Petetin, N; Poncelet, P; Warembourg, A, 1989) |
| "90 min on chronic administration of nicardipine; insulin 2." | 1.28 | Effect of nicardipine on insulin secretion, glucose and lipid metabolism in hypertensive, non-insulin dependent diabetics. ( Capaldo, B; Di Bonito, P; Ferrara, AL; Iovine, C; Mancini, M; Pasanisi, F; Vaccaro, O, 1989) |
| " The dose-response relations for the increase in blood pressure of rats receiving endothelin were comparable with those of rats receiving angiotensin II." | 1.28 | Characteristics of pressor response to endothelin in spontaneously hypertensive and Wistar-Kyoto rats. ( Goto, K; Ishikawa, T; Ito, I; Kimura, S; Masaki, T; Miyauchi, T; Sugishita, Y; Tomobe, Y; Yanagisawa, M, 1989) |
| "Nicardipine was administered to 10 untreated mild-moderate essential hypertensive patients." | 1.28 | Calcium entry blockade, autonomic activity and exercise performance in essential hypertensive patients. ( Alicandri, C; Boni, E; Cantalamessa, A; Corda, L; Fariello, R; Muiesan, G; Zaninelli, A, 1989) |
| "Nicardipine was then administered intravenously at 20 micrograms/kg/min over 2 minutes while the angiotensin II infusion was maintained." | 1.28 | Placental vascular responses to nicardipine in the hypertensive ewe. ( Parisi, VM; Salinas, J; Stockmar, EJ, 1989) |
| "Nicardipine does not cause any chronic activation of the sympathetic nervous system or the renin-angiotensin system." | 1.28 | Nicardipine in the elderly hypertensive: a review of experience in the United Kingdom. ( Littler, WA, 1989) |
| "Nicardipine-based treatment is therefore effective, safe, and well tolerated in elderly hypertensive patients with concomitant disease." | 1.28 | The clinical performance of nicardipine in elderly hypertensive patients with concomitant diseases. ( Leonetti, G, 1989) |
| "The degree of cerebral ischemia 4 hr after BLCL was estimated by the levels of brain energy metabolites (ATP, lactate, c-AMP) and brain water content." | 1.27 | [Influence of long-term antihypertensive treatment on cerebral ischemia induced by bilateral common carotid artery ligation in SHRSR--protective effect of nicardipine hydrochloride]. ( Katayama, Y; Memezawa, H; Nagazumi, A; Sugimoto, S; Suzuki, S; Terashi, A, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 141 (29.25) | 18.7374 |
| 1990's | 193 (40.04) | 18.2507 |
| 2000's | 66 (13.69) | 29.6817 |
| 2010's | 59 (12.24) | 24.3611 |
| 2020's | 23 (4.77) | 2.80 |
| Authors | Studies |
|---|---|
| Martini, BE | 1 |
| Schalk, AL | 1 |
| Colomy, VV | 1 |
| Reinaker, TS | 1 |
| Saldana, S | 1 |
| Breslin, J | 1 |
| Hanify, J | 1 |
| Heierman, T | 1 |
| Larizadeh, K | 1 |
| Sanchez, M | 1 |
| Phipps, W | 1 |
| Brown, CS | 1 |
| Oliveira J E Silva, L | 1 |
| Mattson, AE | 1 |
| Cabrera, D | 1 |
| Farrell, K | 1 |
| Gerberi, DJ | 1 |
| Rabinstein, AA | 1 |
| Ng, Y | 1 |
| Qi, W | 1 |
| King, NKK | 1 |
| Christianson, T | 1 |
| Krishnamoorthy, V | 2 |
| Shah, S | 2 |
| Divani, A | 1 |
| Bettin, M | 1 |
| Coleman, ER | 1 |
| Flaherty, ML | 1 |
| Walsh, KB | 1 |
| Testai, FD | 1 |
| McCauley, JL | 1 |
| Gilkerson, LA | 1 |
| Langefeld, CD | 1 |
| Behymer, TP | 1 |
| Woo, D | 1 |
| James, ML | 1 |
| Lushaj, E | 1 |
| Hermsen, JL | 1 |
| Nelson, K | 1 |
| Amond, K | 1 |
| Bogenschutz, M | 1 |
| Arndt, S | 1 |
| Wilhelm, M | 1 |
| Anagnostopoulos, PV | 1 |
| Nij Bijvank, SW | 1 |
| Hengst, M | 1 |
| Cornette, JC | 1 |
| Huigen, S | 1 |
| Winkelen, AV | 1 |
| Edens, MA | 2 |
| Duvekot, JJ | 3 |
| Kim, MK | 1 |
| Choe, KR | 1 |
| Jeong, DE | 1 |
| Lee, KN | 1 |
| Cho, I | 1 |
| Kim, HJ | 1 |
| Park, JY | 1 |
| Seifi, A | 1 |
| Azari Jafari, A | 1 |
| Mirmoeeni, S | 1 |
| Shah, M | 1 |
| Azari Jafari, M | 1 |
| Nazari, S | 1 |
| Asgarzadeh, S | 1 |
| Godoy, DA | 1 |
| Ibarra, F | 1 |
| Holzmann, S | 1 |
| Fountain, C | 1 |
| Saleh, S | 1 |
| Kapoor, V | 1 |
| Dang, T | 1 |
| Farley, TM | 1 |
| Carrera, JF | 1 |
| Sorace, BJ | 1 |
| Worrall, BB | 1 |
| Southerland, AM | 1 |
| Chiota-McCollum, NA | 1 |
| Borrell-Vega, J | 1 |
| Uribe, AA | 1 |
| Palettas, M | 1 |
| Bergese, SD | 1 |
| Villarreal, EG | 1 |
| Flores, S | 1 |
| Kriz, C | 1 |
| Iranpour, N | 1 |
| Bronicki, RA | 1 |
| Loomba, RS | 1 |
| Zhu, Z | 1 |
| Bower, M | 1 |
| Stern-Nezer, S | 1 |
| Atallah, S | 1 |
| Stradling, D | 1 |
| Groysman, L | 1 |
| Dastur, CK | 1 |
| Akbari, Y | 1 |
| Yu, W | 1 |
| Miller, J | 1 |
| McNaughton, C | 1 |
| Joyce, K | 1 |
| Binz, S | 1 |
| Levy, P | 3 |
| Qi, H | 2 |
| Qin, J | 2 |
| Ren, L | 2 |
| Li, L | 2 |
| Lan, L | 2 |
| Yan, Y | 2 |
| Gan, S | 2 |
| Zhang, Y | 3 |
| Breslin, N | 1 |
| Baptiste, C | 1 |
| Miller, R | 1 |
| Fuchs, K | 1 |
| Goffman, D | 1 |
| Gyamfi-Bannerman, C | 1 |
| D'Alton, M | 1 |
| Raggi, JR | 1 |
| O'Connell, TW | 1 |
| Singer, DJ | 1 |
| Fuss, D | 1 |
| Gondé, H | 1 |
| Lamoureux, F | 1 |
| Pereira, T | 1 |
| Colnot, M | 1 |
| Buchbinder, N | 1 |
| Coquard, A | 1 |
| Varin, R | 1 |
| Hervouët, C | 1 |
| Xiang, B | 1 |
| El-Ghoroury, H | 1 |
| Sudekum, DM | 1 |
| Hecht, JP | 2 |
| Teng, CH | 1 |
| Yang, IH | 1 |
| Wu, MN | 1 |
| Chou, PS | 1 |
| Starr, JB | 1 |
| Tirschwell, DL | 1 |
| Becker, KJ | 1 |
| Stone, ML | 1 |
| Kelly, J | 1 |
| Mistry, M | 1 |
| Buck, M | 1 |
| Gangemi, J | 1 |
| Vergales, J | 1 |
| Richards, PG | 1 |
| Kawada, K | 3 |
| Ohta, T | 2 |
| Tanaka, K | 4 |
| Miyamoto, N | 1 |
| Rosenfeldt, Z | 1 |
| Conklen, K | 1 |
| Jones, B | 1 |
| Ferrill, D | 1 |
| Deshpande, M | 1 |
| Siddiqui, FM | 1 |
| Qureshi, AI | 5 |
| Palesch, YY | 4 |
| Foster, LD | 1 |
| Barsan, WG | 2 |
| Goldstein, JN | 3 |
| Hanley, DF | 2 |
| Hsu, CY | 2 |
| Moy, CS | 2 |
| Qureshi, MH | 1 |
| Silbergleit, R | 2 |
| Suarez, JI | 2 |
| Toyoda, K | 4 |
| Yamamoto, H | 2 |
| Cobb, A | 1 |
| Thornton, L | 2 |
| Garner, O | 1 |
| Ramirez, A | 1 |
| Iardino, A | 1 |
| Yamaguchi, Y | 2 |
| Koga, M | 2 |
| Sato, S | 1 |
| Yamagami, H | 1 |
| Todo, K | 1 |
| Okuda, S | 1 |
| Okada, Y | 1 |
| Kimura, K | 1 |
| Shiokawa, Y | 1 |
| Kamiyama, K | 1 |
| Itabashi, R | 1 |
| Hasegawa, Y | 1 |
| Kario, K | 1 |
| Fujita, K | 1 |
| Kumamoto, M | 1 |
| Kamimura, T | 1 |
| Ando, D | 1 |
| Ide, T | 1 |
| Yoshimoto, T | 1 |
| Shiozawa, M | 1 |
| Matsubara, S | 1 |
| Yoshimura, S | 1 |
| Nagatsuka, K | 2 |
| Lichtenstein, SJ | 1 |
| Herring, MJ | 1 |
| Baxi, PV | 1 |
| Abrams, RI | 1 |
| Korbet, SM | 1 |
| Zamami, Y | 1 |
| Kouno, Y | 1 |
| Niimura, T | 1 |
| Chuma, M | 1 |
| Imai, T | 1 |
| Mitsui, M | 1 |
| Koyama, T | 1 |
| Kayano, M | 1 |
| Okada, N | 1 |
| Hamano, H | 1 |
| Goda, M | 1 |
| Imanishi, M | 5 |
| Takechi, K | 1 |
| Horinouchi, Y | 1 |
| Kondo, Y | 2 |
| Yanagawa, H | 1 |
| Kitamura, Y | 1 |
| Sendo, T | 1 |
| Ujike, Y | 1 |
| Ishizawa, K | 1 |
| Sadeghi, M | 1 |
| Saber, H | 1 |
| Singh, A | 1 |
| Hanni, C | 1 |
| Parker, D | 3 |
| Desai, A | 1 |
| Mohamed, W | 1 |
| Liu-DeRyke, X | 2 |
| Levy, PD | 3 |
| Coplin, W | 1 |
| Rhoney, DH | 3 |
| Inamasu, J | 1 |
| Oheda, M | 1 |
| Hayashi, T | 1 |
| Kato, Y | 3 |
| Hirose, Y | 1 |
| Nooij, LS | 1 |
| Visser, S | 1 |
| Meuleman, T | 1 |
| Vos, P | 1 |
| Roelofs, R | 1 |
| de Groot, CJ | 1 |
| Farias, S | 1 |
| Peacock, WF | 5 |
| Gonzalez, M | 1 |
| Varon, J | 5 |
| Soto-Ruiz, KM | 1 |
| Baumann, BM | 2 |
| Borczuk, P | 2 |
| Cannon, CM | 2 |
| Chandra, A | 3 |
| Cline, DM | 2 |
| Diercks, DB | 1 |
| Hiestand, B | 2 |
| Hsu, A | 2 |
| Jois-Bilowich, P | 2 |
| Kaminski, B | 2 |
| Nowak, RM | 2 |
| Schrock, JW | 2 |
| Aronson, S | 3 |
| Dasta, JF | 1 |
| Levy, JH | 2 |
| Lumb, PD | 2 |
| Fontes, M | 1 |
| Wang, Y | 2 |
| Crothers, TA | 1 |
| Sulham, KA | 1 |
| Navetta, MS | 1 |
| Bernard, E | 1 |
| Goutelle, S | 1 |
| Bertrand, Y | 1 |
| Bleyzac, N | 1 |
| Bebawy, JF | 2 |
| Houston, CC | 1 |
| Kosky, JL | 1 |
| Badri, AM | 1 |
| Hemmer, LB | 1 |
| Moreland, NC | 1 |
| Carabini, LM | 1 |
| Koht, A | 1 |
| Gupta, DK | 2 |
| Cornette, J | 1 |
| Buijs, EA | 1 |
| Herzog, E | 1 |
| Roos-Hesselink, JW | 1 |
| Rizopoulos, D | 1 |
| Meima, M | 1 |
| Steegers, EA | 2 |
| Freiermuth, CE | 1 |
| Bijvank, SW | 1 |
| Visser, W | 1 |
| Roofthooft, DW | 1 |
| Vulto, AG | 1 |
| Hanff, LM | 1 |
| Sassi, MB | 1 |
| Gaies, E | 1 |
| Salouage, I | 1 |
| Trabelsi, S | 1 |
| Lakhal, M | 1 |
| Klouz, A | 1 |
| Abboud, ME | 1 |
| Frasure, SE | 1 |
| Wilson, T | 1 |
| Sharma, D | 1 |
| Vavilala, MS | 1 |
| Carey, MC | 1 |
| Gerstein, NS | 1 |
| Rollstin, AD | 1 |
| McKay, C | 1 |
| Hall, AB | 1 |
| Cortes, J | 1 |
| Jaarin, K | 1 |
| Foong, WD | 1 |
| Yeoh, MH | 1 |
| Kamarul, ZY | 1 |
| Qodriyah, HM | 1 |
| Azman, A | 1 |
| Zuhair, JS | 1 |
| Juliana, AH | 1 |
| Kamisah, Y | 1 |
| Mastropietro, CW | 1 |
| Arango Uribe, D | 1 |
| Komura, SN | 1 |
| Awad, NI | 1 |
| Martin, RL | 1 |
| Steiner, T | 1 |
| Yoon, BW | 1 |
| Kurowski, D | 1 |
| Mullen, MT | 1 |
| Messé, SR | 1 |
| Kadoguchi, N | 1 |
| Yamamoto, S | 1 |
| Morimoto, M | 1 |
| Ishikawa, K | 2 |
| Omori, K | 1 |
| Takeuchi, I | 1 |
| Jitsuiki, K | 1 |
| Yoshizawa, T | 1 |
| Ohsaka, H | 1 |
| Nakao, Y | 1 |
| Yamamoto, T | 1 |
| Yanagawa, Y | 1 |
| Finger, JR | 1 |
| Kurczewski, LM | 1 |
| Brophy, GM | 1 |
| Awaji, K | 1 |
| Inokuchi, R | 1 |
| Maehara, H | 1 |
| Kira, K | 1 |
| Doi, K | 1 |
| Morimura, N | 1 |
| Bozzano, V | 1 |
| Carandini, T | 1 |
| Darteyre, S | 1 |
| Ludwig, C | 1 |
| Lalande, M | 1 |
| Rodière, M | 1 |
| Guillaumont, S | 1 |
| Morin, D | 1 |
| Denier, C | 1 |
| Bouteredjiret, T | 1 |
| Dreyfus, M | 1 |
| Lacroix, C | 1 |
| Adams, D | 1 |
| Roitberg, BZ | 1 |
| Hardman, J | 1 |
| Urbaniak, K | 1 |
| Merchant, A | 1 |
| Mangubat, EZ | 1 |
| Alaraj, A | 1 |
| Mlinarevich, N | 1 |
| Watson, KS | 1 |
| Ruland, S | 1 |
| Batisse, M | 1 |
| Somda, F | 1 |
| Delorme, JP | 1 |
| Desbiez, F | 1 |
| Thieblot, P | 1 |
| Tauveron, I | 1 |
| Dyke, CM | 1 |
| Stierer, KA | 1 |
| Cheung, AT | 1 |
| Kereiakes, DJ | 1 |
| Newman, MF | 1 |
| Abiko, M | 1 |
| Ikawa, F | 1 |
| Obayashi, N | 1 |
| Kajiwara, Y | 1 |
| Mitsuhara, T | 1 |
| Ichinose, N | 1 |
| Inagawa, T | 1 |
| Hashimoto, M | 1 |
| Johkura, K | 1 |
| Ichikawa, T | 1 |
| Kojima, A | 1 |
| Nishimura, S | 1 |
| Shinonaga, M | 1 |
| Marik, PE | 3 |
| Fukagawa, H | 1 |
| Hashiguchi, M | 1 |
| Ayabe, Y | 1 |
| Ando, T | 1 |
| Nakamura, K | 1 |
| Narotam, PK | 1 |
| Puri, V | 1 |
| Roberts, JM | 1 |
| Taylon, C | 1 |
| Vora, Y | 1 |
| Nathoo, N | 1 |
| Reddy, P | 1 |
| Yeh, YC | 1 |
| Cohen, DL | 1 |
| Townsend, RR | 1 |
| Kosaka, T | 1 |
| Nakagawa, M | 1 |
| Ishida, M | 1 |
| Iino, K | 1 |
| Watanabe, H | 1 |
| Hasegawa, H | 1 |
| Ito, H | 2 |
| Hoang, TD | 1 |
| Bao, VQ | 1 |
| Phat, VH | 1 |
| Martin, R | 2 |
| Novitzke, J | 2 |
| Cruz-Flores, S | 2 |
| Ehtisham, A | 2 |
| Ezzeddine, MA | 2 |
| Hussein, HM | 2 |
| Suri, MF | 2 |
| Tariq, N | 2 |
| Thomas, CA | 1 |
| Moffett, BS | 1 |
| Wagner, JL | 1 |
| Mott, AR | 1 |
| Feig, DI | 1 |
| Kishimoto, S | 1 |
| Hirota, K | 4 |
| Segawa, H | 1 |
| Fukuda, K | 1 |
| Kitamura, M | 1 |
| Furusu, A | 1 |
| Hirose, M | 1 |
| Nishino, T | 1 |
| Obata, Y | 1 |
| Uramatsu, T | 1 |
| Kohno, S | 1 |
| Nishikawa, T | 2 |
| Ueba, T | 1 |
| Kajiwara, M | 1 |
| Iwata, R | 1 |
| Miyamatsu, N | 1 |
| Yamashita, K | 1 |
| Hooper, DK | 2 |
| Carle, AC | 1 |
| Schuchter, J | 1 |
| Goebel, J | 2 |
| Wong, MF | 1 |
| Yen, ZS | 1 |
| Pierce, WA | 1 |
| Hederman, AD | 1 |
| Gordon, CJ | 1 |
| Ostrenga, AR | 1 |
| Herrington, B | 1 |
| Kirmani, JF | 2 |
| Liu, Y | 1 |
| van den Born, BJ | 1 |
| Beutler, JJ | 1 |
| Gaillard, CA | 1 |
| de Gooijer, A | 1 |
| van den Meiracker, AH | 1 |
| Kroon, AA | 1 |
| Diercks, D | 1 |
| Hilleman, DE | 2 |
| Rivera, R | 1 |
| Malesker, MA | 1 |
| Ryu, JH | 1 |
| Apfel, CC | 1 |
| Whelan, R | 1 |
| Jeon, YT | 1 |
| Hwang, JW | 1 |
| Do, SH | 1 |
| Ro, YJ | 1 |
| Kim, CS | 1 |
| Fukuda, T | 1 |
| Gardiner, R | 1 |
| Logan, B | 1 |
| Roy-Chaudhury, A | 1 |
| Kirby, CL | 1 |
| Vinks, AA | 1 |
| Woloszyn, AV | 1 |
| McAllen, KJ | 1 |
| Figueroa, BE | 1 |
| DeShane, RS | 1 |
| Barletta, JF | 1 |
| Ortega-Gutierrez, S | 1 |
| Thomas, J | 1 |
| Reccius, A | 1 |
| Agarwal, S | 1 |
| Lantigua, H | 1 |
| Li, M | 1 |
| Carpenter, AM | 1 |
| Mayer, SA | 1 |
| Schmidt, JM | 1 |
| Lee, K | 1 |
| Claassen, J | 1 |
| Badjatia, N | 1 |
| Lesch, C | 1 |
| Elatrous, S | 1 |
| Nouira, S | 1 |
| Ouanes Besbes, L | 1 |
| Marghli, S | 1 |
| Boussarssar, M | 1 |
| Sakkouhi, M | 1 |
| Abroug, F | 1 |
| Ito, T | 2 |
| Yamakawa, H | 1 |
| Bregonzio, C | 1 |
| Terrón, JA | 1 |
| Falcón-Neri, A | 1 |
| Saavedra, JM | 1 |
| Rakić, D | 1 |
| Rumboldt, Z | 2 |
| Bagatin, J | 2 |
| Polić, S | 1 |
| Suzuki, S | 2 |
| Ohtsuka, S | 1 |
| Yamaguchi, I | 1 |
| Denolle, T | 1 |
| Sassano, P | 6 |
| Allain, H | 1 |
| Bentué-Ferrer, D | 1 |
| Breton, S | 1 |
| Cimarosti, I | 1 |
| Ouatara, B | 1 |
| Merienne, M | 1 |
| Gandon, JM | 1 |
| Mounier-Véhier, C | 1 |
| Jaboureck, O | 1 |
| Emeriau, JP | 1 |
| Bernaud, C | 1 |
| Clerson, P | 1 |
| Carre, A | 2 |
| McBride, BF | 1 |
| White, CM | 1 |
| Campbell, M | 1 |
| Frey, BM | 1 |
| Kouoh, F | 1 |
| Gressier, B | 1 |
| Dine, T | 1 |
| Luyckx, M | 1 |
| Brunet, C | 1 |
| Ballester, L | 1 |
| Cazin, JC | 1 |
| Cissé, CT | 1 |
| Faye Dieme, ME | 1 |
| Ngabo, D | 1 |
| Mbaye, M | 1 |
| Diagne, PM | 1 |
| Moreau, JC | 1 |
| Kabara, S | 1 |
| Kushikata, T | 1 |
| Kitayama, M | 1 |
| Ishihara, H | 5 |
| Matsuki, A | 5 |
| Amenta, F | 8 |
| Tomassoni, D | 1 |
| Elliott, WJ | 1 |
| White, PF | 2 |
| Perdue, L | 1 |
| Downing, M | 1 |
| Henry, A | 1 |
| Charpiat, B | 1 |
| Vial, T | 1 |
| Franchini, S | 1 |
| Cuilleret, FJ | 1 |
| Milon, H | 1 |
| Sugiyama, A | 1 |
| Satoh, Y | 1 |
| Takahara, A | 1 |
| Ando, K | 1 |
| Nakamura, Y | 1 |
| Hashimoto, K | 1 |
| Okano, H | 2 |
| Ohkubo, C | 2 |
| Harris-Lane, P | 1 |
| Ahmed, S | 1 |
| Jacob, M | 1 |
| Zada, Y | 1 |
| Divani, AA | 1 |
| Kita, T | 1 |
| Suzuki, Y | 1 |
| Eto, T | 1 |
| Kitamura, K | 1 |
| Carhuapoma, JR | 1 |
| Ulatowski, JA | 1 |
| Curran, MP | 1 |
| Robinson, DM | 1 |
| Keating, GM | 1 |
| Audibert, G | 1 |
| Charpentier, C | 1 |
| Seguin-Devaux, C | 1 |
| Charretier, PA | 1 |
| Grégoire, H | 1 |
| Devaux, Y | 1 |
| Perrier, JF | 1 |
| Longrois, D | 1 |
| Mertes, PM | 1 |
| Frishman, WH | 3 |
| Veresh, M | 1 |
| Schlocker, SJ | 1 |
| Tejani, N | 1 |
| Sahney, S | 1 |
| Kumazawa, M | 1 |
| Iida, H | 1 |
| Uchida, M | 2 |
| Iida, M | 1 |
| Takenaka, M | 1 |
| Dohi, S | 1 |
| Miyajima, S | 1 |
| Nemoto, K | 1 |
| Sekimoto, M | 1 |
| Kinae, Y | 1 |
| Kasahara, T | 1 |
| Souma, S | 1 |
| Degawa, M | 1 |
| Nakamoto, M | 1 |
| Ohya, Y | 1 |
| Sakima, A | 1 |
| Yamazato, M | 1 |
| Takishita, S | 2 |
| Wong, GK | 1 |
| Poon, WS | 1 |
| Janisse, J | 1 |
| Coplin, WM | 1 |
| Norris, G | 1 |
| Nozawa, H | 1 |
| Akiyama, Y | 1 |
| Sunaga, S | 1 |
| Tsurita, G | 1 |
| Addad, F | 1 |
| Ferjani, H | 1 |
| Chaabani, A | 1 |
| Jelliti, M | 1 |
| Gamra, H | 1 |
| Makni, H | 1 |
| Khaldoun, BH | 1 |
| Dridi, Z | 1 |
| Ben Farhat, M | 1 |
| Lew, W | 1 |
| Weaver, FA | 1 |
| Muntazar, M | 1 |
| Goldberg, ME | 2 |
| Ziegler, MG | 2 |
| Woodson, LC | 1 |
| Müller, FB | 1 |
| Bolli, P | 3 |
| Erne, P | 1 |
| Kiowski, W | 1 |
| Bühler, FR | 3 |
| Hulthén, UL | 3 |
| Forette, F | 3 |
| Bellet, M | 7 |
| Henry, JF | 3 |
| Hervy, MP | 3 |
| Poyard-Salmeron, C | 2 |
| Bouchacourt, P | 3 |
| Giudicelli, JF | 1 |
| Freslon, JL | 1 |
| Richer, C | 1 |
| Kishi, Y | 2 |
| Okumura, F | 3 |
| Furuya, H | 1 |
| Sakata, S | 1 |
| Miura, K | 1 |
| Silke, B | 3 |
| Ahuja, RC | 1 |
| Okoli, RC | 1 |
| Nelson, GI | 1 |
| Taylor, SH | 3 |
| Jones, RI | 1 |
| Hornung, RS | 1 |
| Sonecha, T | 1 |
| Raftery, EB | 1 |
| Young, MA | 4 |
| Watson, RD | 2 |
| Littler, WA | 6 |
| Kaburagi, T | 2 |
| Yokoyama, S | 2 |
| van Schaik, BA | 1 |
| van Nistelrooy, AE | 1 |
| Geyskes, GG | 1 |
| Takabatake, T | 2 |
| Ohta, H | 1 |
| Yamamoto, Y | 2 |
| Maekawa, M | 1 |
| Arai, S | 1 |
| Hattori, N | 1 |
| Nomura, G | 1 |
| Higuchi, S | 2 |
| Kawamura, S | 1 |
| Delhumeau, A | 1 |
| Granry, JC | 1 |
| Cottineau, C | 1 |
| Bukowski, JG | 1 |
| Corbeau, JJ | 1 |
| Moreau, X | 1 |
| Tobias, JD | 5 |
| Lowe, S | 1 |
| Deshpande, JK | 1 |
| Fujii, Y | 2 |
| Tanaka, H | 3 |
| Saitoh, Y | 1 |
| Toyooka, H | 2 |
| Saijyo, T | 1 |
| Hattori, O | 1 |
| Suzuki, K | 1 |
| Hara, T | 1 |
| Deguchi, T | 1 |
| Sasaki, H | 1 |
| Naka, K | 1 |
| Ohoshi, T | 1 |
| Hagihara, T | 1 |
| Matsuo, H | 1 |
| Sowa, R | 1 |
| Matsumoto, G | 1 |
| Sanke, T | 1 |
| Nanjo, K | 1 |
| Dohi, Y | 2 |
| Kojima, M | 2 |
| Sato, K | 3 |
| Hirata, H | 2 |
| Asanuma, M | 1 |
| Ogawa, N | 1 |
| Tsoucaris, D | 1 |
| Benetos, A | 2 |
| Legrand, M | 2 |
| London, GM | 1 |
| Safar, ME | 3 |
| Sukonthasarn, A | 1 |
| Sabbatini, M | 5 |
| Strocchi, P | 2 |
| Ikeno, A | 1 |
| Nose, I | 1 |
| Fukuya, F | 1 |
| Minato, H | 1 |
| Takeyama, K | 1 |
| Hosoki, K | 1 |
| Karasawa, T | 1 |
| Huguet, F | 1 |
| Brisac, AM | 2 |
| Dubar, M | 1 |
| Ingrand, P | 1 |
| Piriou, A | 1 |
| Palatini, P | 1 |
| Casiglia, E | 1 |
| Graniero, GR | 1 |
| Dorigatti, F | 1 |
| Lotoro, F | 1 |
| Vriz, O | 1 |
| Pessina, AC | 1 |
| Takaba, T | 1 |
| Yokokawa, H | 1 |
| Moriyasu, K | 1 |
| Matsuo, Y | 1 |
| Kataoka, D | 1 |
| Habib, GB | 1 |
| Dunbar, LM | 1 |
| Rodrigues, R | 1 |
| Neale, AC | 1 |
| Friday, KJ | 2 |
| Klassen, DK | 1 |
| Jane, LH | 1 |
| Young, DY | 1 |
| Peterson, CA | 1 |
| Kudo, T | 2 |
| Kudo, M | 1 |
| Hashimoto, H | 2 |
| Koh, H | 3 |
| Kuramoto, K | 5 |
| Kato, T | 1 |
| Noguchi, K | 1 |
| Sakanashi, M | 1 |
| Hirayama, T | 1 |
| Katayama, Y | 2 |
| Kano, T | 1 |
| Tsubokawa, T | 1 |
| Ferrante, F | 4 |
| Abbate, F | 2 |
| Ciriaco, E | 3 |
| Polidori, C | 1 |
| Neutel, JM | 1 |
| Smith, DH | 1 |
| Wallin, D | 1 |
| Cook, E | 3 |
| Ram, CV | 6 |
| Fletcher, E | 2 |
| Maher, KE | 1 |
| Turlepaty, P | 1 |
| Grandy, S | 2 |
| Lee, R | 1 |
| Raccah, D | 1 |
| Pettenuzzo-Mollo, M | 1 |
| Provendier, O | 1 |
| Boucher, L | 1 |
| Cozic, JA | 1 |
| Gorlier, R | 1 |
| Huin, P | 1 |
| Sicard, J | 1 |
| Vague, P | 1 |
| Bilello, K | 1 |
| Schultz, S | 1 |
| Powell, C | 1 |
| Jaffin, J | 1 |
| Cole, F | 1 |
| Malcolm, D | 1 |
| Oizumi, K | 2 |
| Miyamoto, M | 1 |
| Koike, H | 3 |
| Sumimoto, T | 2 |
| Hiwada, K | 4 |
| Ochi, T | 2 |
| Matsubara, W | 1 |
| Joh, T | 2 |
| Imamura, Y | 1 |
| Shirahase, H | 1 |
| Uehara, Y | 1 |
| Wada, K | 1 |
| Shimaji, H | 1 |
| Ishimitsu, T | 1 |
| Hashizume, Y | 1 |
| Kanda, M | 1 |
| Nakamura, S | 2 |
| Ricci, A | 2 |
| Larsen, A | 1 |
| Kurashina, T | 1 |
| Sakamaki, T | 1 |
| Yagi, A | 1 |
| Nakamura, T | 1 |
| Sakamoto, H | 1 |
| Nushiro, N | 1 |
| Jannet, D | 2 |
| Carbonne, B | 2 |
| Sebban, E | 1 |
| Milliez, J | 2 |
| Kageyama, S | 1 |
| Yamamoto, J | 1 |
| Mimura, A | 1 |
| Ishibashi, K | 1 |
| Sakurai, T | 1 |
| Yokota, K | 1 |
| Isogai, Y | 1 |
| Fujita, T | 1 |
| Arosio, E | 4 |
| Pancera, P | 4 |
| Seiban, I | 1 |
| Priante, F | 4 |
| Ribul, M | 3 |
| De Marchi, S | 2 |
| Montresor, G | 1 |
| Lechi, A | 4 |
| Muratani, H | 1 |
| Sesoko, S | 1 |
| Teruya, H | 1 |
| Tozawa, M | 1 |
| Fukiyama, K | 2 |
| Inada, Y | 1 |
| Sheiban, I | 1 |
| Zannoni, M | 3 |
| Borow, KM | 1 |
| Neumann, A | 1 |
| Lang, RM | 1 |
| Ehler, D | 1 |
| Valentine-Bates, B | 1 |
| Wolff, A | 1 |
| Friday, K | 1 |
| Murphy, M | 1 |
| Weir, B | 1 |
| MacDonald, L | 1 |
| Ueda, M | 1 |
| Masui, M | 1 |
| Kawakami, M | 1 |
| Matsunaga, K | 1 |
| Gemba, T | 1 |
| Ninomiya, M | 1 |
| Nakano, A | 1 |
| Torii, M | 1 |
| Adachi, I | 1 |
| Kuriyama, Y | 1 |
| Sawada, T | 1 |
| Omae, T | 3 |
| Tedeschi, C | 1 |
| Guarini, P | 1 |
| Giordano, G | 1 |
| Messina, V | 1 |
| Cicatiello, AM | 1 |
| Iovino, L | 1 |
| Tagliamonte, MR | 1 |
| Treluyer, JM | 1 |
| Hubert, P | 1 |
| Jouvet, P | 1 |
| Couderc, S | 1 |
| Cloup, M | 1 |
| De Cesaris, R | 5 |
| Ranieri, G | 5 |
| Andriani, A | 4 |
| Filitti, V | 4 |
| Bonfantino, MV | 3 |
| Lamontanara, G | 2 |
| Ferrieri, A | 2 |
| Abe, K | 3 |
| Demizu, A | 1 |
| Iwanaga, H | 2 |
| Bonfantino, V | 1 |
| Adriani, A | 1 |
| Drici, MD | 1 |
| Raucoules, M | 1 |
| Jacomet, Y | 1 |
| Iacono, P | 1 |
| Ichai, C | 1 |
| Grimaud, D | 1 |
| Lapalus, P | 1 |
| Inagaki, Y | 1 |
| Fagan, TC | 3 |
| Tyler, ED | 1 |
| Reitman, MA | 1 |
| Kenley, S | 1 |
| Weber, MA | 1 |
| Natsume, T | 1 |
| Arriaga-Gracia, J | 1 |
| Sánchez-Garcia, JL | 1 |
| González-García, CA | 1 |
| Tsoucaris-Kupfer, D | 1 |
| Oshita, S | 2 |
| Nakakimura, K | 1 |
| Kaieda, R | 1 |
| Murakawa, T | 1 |
| Tamura, H | 1 |
| Hiraoka, I | 1 |
| Hashimoto, Y | 2 |
| Takagi, H | 1 |
| Soto Alvarez, J | 1 |
| Wu, KD | 1 |
| Hsieh, BS | 1 |
| Chu, TS | 1 |
| Yen, TS | 1 |
| Bigazzi, R | 1 |
| Bianchi, S | 1 |
| Baldari, D | 1 |
| Sgherri, G | 1 |
| Baldari, G | 1 |
| Campese, VM | 1 |
| Wang, DJ | 1 |
| Shen, DC | 1 |
| Sheu, WH | 1 |
| Chu, NF | 1 |
| Fuh, MM | 1 |
| Chen, LM | 1 |
| Touboul, C | 1 |
| Khelifati, Y | 1 |
| Weir, MR | 2 |
| Wright, JT | 1 |
| Ferdinand, KC | 1 |
| Cook, CA | 1 |
| Champion, D | 2 |
| Wong, S | 1 |
| Jenkins, PA | 1 |
| Kong, BW | 1 |
| Mercuro, G | 1 |
| Rossetti, ZL | 1 |
| Lai, L | 1 |
| Manca, MR | 1 |
| Longu, G | 1 |
| Ruscazio, M | 1 |
| Cherchi, A | 1 |
| Abdelwahab, W | 1 |
| Frishman, W | 1 |
| Landau, A | 1 |
| Benvenuti, C | 1 |
| Guerini Rocco, C | 1 |
| Trezzi, P | 1 |
| Kumagai, K | 1 |
| Suzuki, H | 3 |
| Ichikawa, M | 1 |
| Jimbo, M | 1 |
| Nishizawa, M | 1 |
| Ryuzaki, M | 1 |
| Saruta, T | 5 |
| Terao, M | 1 |
| Kubota, M | 1 |
| Tamakawa, S | 1 |
| Ogawa, H | 1 |
| Sato, Y | 1 |
| Iwase, M | 1 |
| Wakisaka, M | 1 |
| Yoshizumi, H | 1 |
| Nunoi, K | 1 |
| Yoshinari, M | 1 |
| Fujishima, M | 3 |
| Iwaoka, T | 1 |
| Inotsume, N | 1 |
| Inoue, J | 1 |
| Naomi, S | 1 |
| Okamoto, Y | 1 |
| Nakano, M | 1 |
| Umeda, T | 1 |
| Guan, D | 1 |
| Wang, R | 1 |
| Lu, J | 1 |
| Wang, M | 1 |
| Xu, C | 1 |
| Aya, AG | 1 |
| Bruelle, P | 1 |
| Lefrant, JY | 1 |
| Saissi, G | 1 |
| Ferrer, JM | 1 |
| Eledjham, JJ | 1 |
| Chen, TL | 1 |
| Sun, WZ | 1 |
| Cheng, YJ | 1 |
| Lee, TS | 1 |
| Lin, SY | 1 |
| Lin, CJ | 1 |
| Dozen, M | 1 |
| Watanabe, K | 1 |
| Hosono, M | 1 |
| Hayashi, Y | 1 |
| Kanno, Y | 1 |
| Okada, H | 1 |
| Takenaka, T | 1 |
| Boissel, JP | 1 |
| Meillard, O | 1 |
| Perrin-Fayolle, E | 1 |
| Ducruet, T | 1 |
| Alamercery, Y | 1 |
| Benghozi, R | 2 |
| Stephan, D | 1 |
| Grima, M | 1 |
| Guignard, M | 1 |
| Barthelmebs, M | 1 |
| Imbs, JL | 1 |
| Groshong, T | 2 |
| Pietsch, JB | 1 |
| Lynch, A | 1 |
| Cavallo, A | 1 |
| Bertocchi, F | 1 |
| Shudo, C | 1 |
| Masuda, Y | 1 |
| Sugita, H | 1 |
| Tamura, T | 1 |
| Furukawa, S | 1 |
| Hayashi, K | 2 |
| Shikada, K | 1 |
| Tanaka, S | 1 |
| Tomita, K | 1 |
| Yajnik, VH | 1 |
| Vatsaraj, DJ | 1 |
| Acharya, HK | 1 |
| Yajnik, NV | 1 |
| Duvoux, C | 1 |
| Cherqui, D | 1 |
| Di Martino, V | 1 |
| Métreau, JM | 1 |
| Salvat, A | 1 |
| Lauzet, JY | 1 |
| Fagniez, PL | 1 |
| Dhumeaux, D | 1 |
| Cavallotti, C | 1 |
| Vincent, JL | 1 |
| Berlot, G | 1 |
| Preiser, JC | 1 |
| Engelman, E | 1 |
| Dereume, JP | 1 |
| Khan, RJ | 1 |
| Zannad, F | 1 |
| Akopov, SE | 1 |
| Simonian, NA | 1 |
| Kazarian, AV | 1 |
| Gouyon, JB | 2 |
| Geneste, B | 1 |
| Semama, DS | 2 |
| Françoise, M | 1 |
| Germain, JF | 2 |
| Muneta, S | 1 |
| Kido, H | 1 |
| Nishikawa, M | 1 |
| Kubo, Y | 1 |
| Ohtaki, Y | 1 |
| Fujino, Y | 1 |
| Egi, Y | 1 |
| Ebisu, H | 1 |
| Inoue, S | 1 |
| Yamanaga, K | 1 |
| Uchida, T | 1 |
| Nakamura, N | 1 |
| Song, D | 1 |
| Singh, H | 1 |
| Gadhiali, M | 1 |
| Griffin, JD | 1 |
| Klein, KW | 1 |
| Miyagawa, K | 1 |
| Kihara, S | 1 |
| Takahashi, S | 2 |
| Combemale, F | 1 |
| Carnaille, B | 1 |
| Tavernier, B | 1 |
| Hautier, MB | 1 |
| Thevenot, A | 1 |
| Scherpereel, P | 1 |
| Proye, C | 1 |
| Carlos, DM | 1 |
| Goto, S | 1 |
| Urata, Y | 1 |
| Iida, T | 1 |
| Cho, S | 1 |
| Niwa, M | 1 |
| Tsuji, Y | 1 |
| Kondo, T | 1 |
| Kitahata, H | 1 |
| Kimura, H | 2 |
| Kawahito, S | 1 |
| Park, YC | 1 |
| Sakabe, T | 1 |
| Prados, P | 1 |
| Matsunaga, H | 1 |
| Mori, T | 1 |
| Santa, T | 1 |
| Fukushima, T | 2 |
| Homma, H | 1 |
| Kasai, C | 1 |
| Imai, K | 1 |
| Funato, H | 1 |
| Watanabe, M | 2 |
| Uemura, A | 1 |
| Iaria, P | 1 |
| Blacher, J | 1 |
| Asplanato, M | 1 |
| Edric, K | 1 |
| Safar, M | 2 |
| Girerd, X | 1 |
| Honda, T | 1 |
| Hamada, M | 1 |
| Shigematsu, Y | 1 |
| Matsumoto, Y | 1 |
| Matsuoka, H | 1 |
| Mikoda, N | 1 |
| Nakagawa, H | 1 |
| Kawahara, K | 1 |
| Vaile, JC | 1 |
| Jordan, PJ | 1 |
| Stallard, TJ | 2 |
| Strauser, LM | 1 |
| Ogihara, T | 2 |
| Shimamura, K | 1 |
| Yamamoto, K | 1 |
| Sekiguchi, F | 1 |
| Sunano, S | 1 |
| Baccar, H | 1 |
| Bezdah, L | 1 |
| Ouechtati, W | 1 |
| Kasri, R | 1 |
| Milou, C | 1 |
| Debuche-Benouachkou, V | 1 |
| Kross, RA | 1 |
| Ferri, E | 1 |
| Leung, D | 1 |
| Pratila, M | 1 |
| Broad, C | 1 |
| Veronesi, M | 1 |
| Melendez, JA | 1 |
| Bronzetti, E | 2 |
| El-Assouad, D | 1 |
| Felici, L | 2 |
| Greco, S | 1 |
| Mariotta, S | 1 |
| Nakatsuma, A | 1 |
| Kawasaki, H | 1 |
| Kurosaki, Y | 1 |
| Futagami, K | 1 |
| Araki, H | 1 |
| Gomita, Y | 1 |
| Muñoz Alameda, LE | 1 |
| Barcina Sánchez, M | 1 |
| Dorman, T | 1 |
| Thompson, DA | 1 |
| Breslow, MJ | 1 |
| Lipsett, PA | 1 |
| Rosenfeld, BA | 1 |
| Sinaiko, AR | 1 |
| Daniels, SR | 1 |
| Flynn, JT | 1 |
| Mottes, TA | 1 |
| Brophy, PD | 1 |
| Kershaw, DB | 1 |
| Smoyer, WE | 1 |
| Bunchman, TE | 1 |
| Kuwajima, I | 1 |
| Iimura, O | 1 |
| Ishii, M | 1 |
| Tsuda, K | 1 |
| Tsuda, S | 1 |
| Nishio, I | 1 |
| Masuyama, Y | 2 |
| Tsutsui, T | 1 |
| Madi-Jebara, S | 1 |
| Khater-Rassi, D | 1 |
| Yazigi, A | 1 |
| Haddad, F | 1 |
| Hayek, G | 1 |
| Achkouty, R | 1 |
| Antakly, MC | 1 |
| Kitazono, T | 1 |
| Ago, T | 1 |
| Kamouchi, M | 1 |
| Santa, N | 1 |
| Ooboshi, H | 1 |
| Ibayashi, S | 1 |
| Kanda, A | 1 |
| Haruno, A | 1 |
| Miyake, H | 1 |
| Nagasaka, M | 1 |
| Chen, JW | 1 |
| Chen, CH | 1 |
| Wang, SP | 1 |
| Chang, MS | 1 |
| Murakami, K | 1 |
| Kimura, G | 3 |
| Sanai, T | 1 |
| Kawano, Y | 3 |
| Kojima, S | 3 |
| Yoshida, K | 3 |
| Abe, H | 3 |
| Ashida, T | 3 |
| Yoshimi, H | 3 |
| Tada, Y | 1 |
| Tsuda, Y | 1 |
| Otsuka, T | 1 |
| Nagasawa, K | 1 |
| Kusaba, T | 1 |
| Sakata, T | 1 |
| Faguer de Moustier, B | 1 |
| Paoli, V | 1 |
| Pedrinelli, R | 5 |
| Taddei, S | 3 |
| Panarace, G | 3 |
| Spessot, M | 2 |
| Salvetti, A | 7 |
| Leonetti, G | 4 |
| Chianca, R | 1 |
| Bosch, X | 1 |
| Sobrino, J | 1 |
| Lopez-Soto, A | 1 |
| Urbano-Marquez, A | 1 |
| Penttila, O | 1 |
| Kanniainen, E | 2 |
| Jounela, A | 1 |
| Huikko, M | 1 |
| Pasanisi, F | 3 |
| Marotta, T | 1 |
| Ferrara, LA | 5 |
| Russo, O | 1 |
| Mancini, M | 3 |
| Fogari, R | 3 |
| Zoppi, A | 2 |
| Malamani, GD | 2 |
| Corradi, L | 2 |
| Mizobuchi, S | 1 |
| Ochiai, Y | 1 |
| Ishii, S | 3 |
| Kaneuchi, M | 1 |
| Tokaji, A | 1 |
| Katayama, H | 1 |
| Goto, F | 1 |
| Kato, S | 1 |
| Sudo, I | 2 |
| Halpern, NA | 3 |
| Goldberg, M | 1 |
| Neely, C | 2 |
| Sladen, RN | 2 |
| Goldberg, JS | 2 |
| Floyd, J | 1 |
| Gabrielson, G | 1 |
| Greenstein, RJ | 1 |
| Mancia, G | 1 |
| Buoninconti, R | 1 |
| Errico, M | 2 |
| Freda, M | 2 |
| Giordano, MP | 1 |
| Granata, Q | 1 |
| Lucentini, ML | 1 |
| Marsili, P | 1 |
| Pasotti, C | 1 |
| Piccolo, E | 1 |
| Gradman, AH | 1 |
| Kaihlanen, PM | 1 |
| Wong, SC | 1 |
| Porchet, HC | 1 |
| Loew, F | 2 |
| Gauthey, L | 2 |
| Dayer, P | 1 |
| Tariq, AR | 1 |
| Maheendran, K | 1 |
| Kamsiah, J | 1 |
| Christina, P | 1 |
| Giugliano, D | 1 |
| Saccomanno, F | 1 |
| Paolisso, G | 1 |
| Ceriello, A | 1 |
| Torella, R | 1 |
| Varricchio, M | 1 |
| D'Onofrio, F | 1 |
| Talamini, G | 1 |
| Kanemoto, N | 1 |
| Nakayama, K | 1 |
| Ide, M | 1 |
| Goto, Y | 1 |
| Dittrich, HC | 1 |
| Adler, J | 1 |
| Ong, J | 1 |
| Reitman, M | 1 |
| Weber, M | 1 |
| Ziegler, M | 1 |
| Omote, K | 1 |
| Kirita, A | 1 |
| Namiki, A | 1 |
| Iwasaki, H | 1 |
| Savi, L | 1 |
| Montebelli, MR | 1 |
| D'Alonzo, S | 1 |
| Mettimano, M | 1 |
| Folli, G | 1 |
| Walker, JJ | 1 |
| Mathers, A | 1 |
| Bjornsson, S | 1 |
| Cameron, AD | 1 |
| Fairlie, FM | 1 |
| Hashimoto, N | 1 |
| Satoh, S | 1 |
| Yamada, Y | 1 |
| Kobayashi, K | 1 |
| Calvo Gómez, C | 1 |
| Lado Lado, FL | 1 |
| Cinos Ramos, L | 1 |
| Pérez Leiros, P | 1 |
| Justo Firvida, E | 1 |
| Antonicelli, R | 1 |
| Pagelli, P | 1 |
| Paciaroni, E | 1 |
| Lacourcière, Y | 1 |
| Poirier, L | 1 |
| Lévesque, C | 1 |
| Provencher, P | 1 |
| Sasaki, T | 1 |
| Imai, M | 1 |
| Amemiya, T | 1 |
| Tettamanti, F | 2 |
| Poletti, L | 2 |
| Borgnino, C | 3 |
| Rosa, A | 1 |
| Rosa, C | 1 |
| Ghione, S | 1 |
| Wirth, AM | 1 |
| Beghé, F | 1 |
| Combes, P | 1 |
| Durand, M | 1 |
| Nicholson, JP | 1 |
| Resnick, LM | 1 |
| Cigarroa, J | 1 |
| Marion, D | 1 |
| Vaughan, ED | 1 |
| Laragh, JH | 2 |
| De Simone, G | 5 |
| Celentano, A | 4 |
| Marcadet, DM | 1 |
| Blanc, AS | 1 |
| Lopez, AA | 1 |
| Preziosi, JP | 1 |
| Guignard, MM | 1 |
| Baggio, S | 1 |
| Champeroux, P | 1 |
| Lacolley, P | 1 |
| Laurent, S | 1 |
| Paris, JV | 1 |
| González, CA | 1 |
| Zhdanov, VF | 1 |
| Amosov, VI | 1 |
| Sinitsyna, TM | 1 |
| Iartseva, EE | 1 |
| Dentamaro, M | 1 |
| Ikeda, M | 2 |
| Kaneko, Y | 1 |
| Yoshinaga, K | 1 |
| Yamada, K | 2 |
| David, D | 3 |
| Dubois, C | 1 |
| Loria, Y | 2 |
| Irie, F | 1 |
| Makita, T | 1 |
| Matsumoto, K | 1 |
| Itohda, Y | 1 |
| Maetzel, FK | 1 |
| Teufel, WE | 1 |
| Griebel, A | 1 |
| Glocke, MH | 1 |
| Astorri, E | 1 |
| Josselson, J | 1 |
| Ekelund, LG | 1 |
| Korc, M | 1 |
| Pool, JL | 1 |
| Stein, GH | 1 |
| Wolbach, RA | 2 |
| Chauveau, D | 1 |
| Houillier, P | 1 |
| Azizi, M | 1 |
| Guyenne, TT | 1 |
| Jeunemaître, X | 2 |
| Plouin, PF | 2 |
| Corvol, P | 5 |
| Webster, J | 2 |
| Petrie, JC | 2 |
| Jeffers, TA | 2 |
| Roy-Chaudhury, P | 1 |
| Crichton, W | 1 |
| Witte, K | 2 |
| Jamieson, M | 1 |
| MacDonald, FC | 2 |
| Beard, M | 1 |
| Dow, RJ | 2 |
| Deguchi, F | 2 |
| Kawamura, M | 2 |
| Katayama, S | 1 |
| Maruno, Y | 1 |
| Itabashi, A | 1 |
| Inaba, M | 1 |
| Omoto, A | 1 |
| Ishii, J | 1 |
| Komsuoğlu, B | 1 |
| Sengün, B | 1 |
| Bayram, A | 1 |
| Komsuoğlu, SS | 1 |
| Le Jeunne, C | 1 |
| Hugues, FC | 1 |
| Munera, Y | 1 |
| Ozanne, H | 1 |
| Kihara, A | 1 |
| Kurokawa, Y | 1 |
| Uede, T | 1 |
| Ohta, K | 1 |
| Honmou, O | 1 |
| Kawashima, K | 1 |
| Toda, H | 1 |
| Oohata, H | 1 |
| Fujimoto, K | 1 |
| Suzuki, T | 1 |
| Inagaki, O | 1 |
| Chernyshev, EP | 1 |
| Amano, N | 1 |
| Kotani, N | 1 |
| Sarica, G | 1 |
| Colson, P | 1 |
| Ribstein, J | 2 |
| Chaptal, PA | 1 |
| Mimran, A | 2 |
| Roquefeuil, B | 1 |
| Valentin, JP | 1 |
| Jover, B | 1 |
| Cristol, JP | 1 |
| Perry, SM | 1 |
| Smith, DW | 1 |
| Meacham, PW | 1 |
| Wood, M | 2 |
| Leonetti Luparini, R | 3 |
| Giarrizzo, C | 3 |
| Onofri, R | 2 |
| Ferri, C | 3 |
| Caparra, A | 2 |
| Germanò, G | 1 |
| Santucci, A | 3 |
| Gökçe, C | 1 |
| Oram, A | 1 |
| Kes, S | 1 |
| Oram, E | 1 |
| Uğurlu, S | 1 |
| Soro, S | 3 |
| Cocca, A | 1 |
| Tommaselli, A | 1 |
| Costantino, G | 3 |
| Alicea, M | 2 |
| Krakoff, LR | 3 |
| Greenstein, R | 2 |
| Mukaiyama, S | 1 |
| Ishii, H | 1 |
| Komaya, T | 1 |
| Tamura, K | 1 |
| Clifton, GG | 6 |
| Wallin, JD | 7 |
| Pepine, CJ | 1 |
| Lambert, CR | 1 |
| Bolognesi, R | 1 |
| Tsialtas, D | 1 |
| Straneo, U | 1 |
| Conti, M | 1 |
| Manca, C | 1 |
| Galderisi, M | 3 |
| Tammaro, P | 3 |
| Garofalo, M | 2 |
| Mureddu, GF | 2 |
| de Divitiis, O | 3 |
| Donath, R | 1 |
| Petitot, C | 1 |
| Herrmann, F | 1 |
| Jacot Des Combes, B | 1 |
| Veglio, F | 1 |
| Pinna, G | 1 |
| Bisbocci, D | 1 |
| Rabbia, F | 1 |
| Piras, D | 1 |
| Chiandussi, L | 1 |
| Clark, S | 1 |
| Joseph, J | 1 |
| Moritz, H | 1 |
| Maguire, D | 1 |
| Seltzer, JL | 1 |
| Turlapaty, P | 4 |
| Gonzalez, DG | 1 |
| Featherston, W | 1 |
| Lugo, C | 1 |
| Ralakis, J | 1 |
| Kaplan, NM | 1 |
| Bienvenu, GS | 3 |
| Laddu, A | 2 |
| Belhani, A | 1 |
| Ben Naceur, M | 1 |
| Lilja, M | 1 |
| Juustila, H | 1 |
| Pasanen, A | 1 |
| Jounela, AJ | 1 |
| Vargas, R | 1 |
| Bienvenu, G | 2 |
| Williams, R | 1 |
| Sambol, N | 1 |
| McMahon, G | 1 |
| Lai, CM | 1 |
| Quon, C | 1 |
| Baba, T | 5 |
| Tomiyama, T | 1 |
| Murabayashi, S | 4 |
| Takebe, K | 5 |
| Montanari, A | 1 |
| Ragni, G | 1 |
| Vallisa, D | 1 |
| Colla, R | 1 |
| Serventi, M | 1 |
| Novarini, A | 2 |
| Coruzzi, P | 2 |
| Sada, T | 2 |
| Ozaki, H | 1 |
| Karaki, H | 1 |
| Tan, J | 1 |
| Kaplan, JA | 1 |
| Donnelly, R | 2 |
| Elliott, HL | 2 |
| Meredith, PA | 2 |
| Reid, JL | 2 |
| Cluzel, P | 1 |
| Chatellier, G | 3 |
| Rivalan, J | 1 |
| Menard, J | 3 |
| Fiasconaro, G | 1 |
| Saviolo, R | 1 |
| Arcaro, G | 1 |
| Montesi, G | 1 |
| Vecht, RJ | 1 |
| Swanson, KT | 1 |
| Nicolaides, EP | 1 |
| Lennox, SC | 1 |
| Gibson, DG | 1 |
| Chamontin, B | 1 |
| Begasse, F | 1 |
| Salvador, M | 1 |
| Fouquoire, B | 1 |
| Poncelet, P | 1 |
| Warembourg, A | 1 |
| Petetin, N | 1 |
| Debrueres, S | 1 |
| van Wezel, HB | 2 |
| Koolen, JJ | 2 |
| Visser, CA | 2 |
| Vergroesen, I | 2 |
| Leyssius, AT | 1 |
| Dijkhuis, JP | 2 |
| Meyne, NG | 1 |
| Deen, L | 2 |
| Begon, C | 1 |
| Dartayet, B | 1 |
| Edouard, A | 1 |
| Samii, K | 1 |
| Iwasaki, T | 1 |
| Niwa, A | 1 |
| Shinoda, T | 1 |
| Ishihara, M | 1 |
| Aizawa, T | 1 |
| Yamada, T | 1 |
| Di Lorenzo, L | 2 |
| Moccia, D | 2 |
| Buonissimo, S | 2 |
| Puccinelli, F | 1 |
| Pieraccini, F | 1 |
| Tomei, GP | 1 |
| Gargiulo, L | 1 |
| Cook, ME | 4 |
| MacCarthy, P | 1 |
| Walsh, M | 1 |
| Gosse, P | 1 |
| Lacroix, P | 1 |
| Roudaut, R | 1 |
| Dallocchio, M | 1 |
| Zadionchenko, VS | 1 |
| Kamenker, ES | 1 |
| Chikvashvili, IA | 1 |
| Baba, A | 1 |
| Arita, M | 1 |
| Morimoto, S | 1 |
| Ohyama, T | 1 |
| Hisaki, K | 1 |
| Matsumura, Y | 1 |
| Pansard, JL | 1 |
| Marty, J | 2 |
| Lançon, JP | 1 |
| Pastor, C | 2 |
| Barbier-Böhm, G | 1 |
| Barbier-Boehm, G | 1 |
| Videcoq, M | 1 |
| Enguerand, D | 1 |
| Sakurai, J | 2 |
| Ikeda, T | 1 |
| Toya, Y | 1 |
| Gomi, T | 1 |
| Ibukiyama, C | 1 |
| Carretta, R | 1 |
| Bardelli, M | 1 |
| Muiesan, S | 1 |
| Vran, F | 1 |
| Fabris, B | 1 |
| Fischetti, F | 1 |
| Campanacci, L | 1 |
| McClaran, J | 1 |
| Vaccaro, O | 1 |
| Ferrara, AL | 1 |
| Di Bonito, P | 1 |
| Capaldo, B | 1 |
| Iovine, C | 1 |
| Lessem, JN | 1 |
| Barone, EJ | 1 |
| Berl, T | 1 |
| Detwiler, J | 1 |
| Lewin, AT | 1 |
| Lubash, GD | 1 |
| Margolis, R | 1 |
| McGowan, RL | 1 |
| Vlachakis, N | 1 |
| Brown, R | 1 |
| Schnaper, H | 1 |
| Smolens, P | 1 |
| Montijo, M | 1 |
| Michelson, E | 1 |
| Conrad, KA | 2 |
| Lessem, J | 1 |
| Freedman, D | 1 |
| Piepho, RW | 1 |
| Sowers, JR | 1 |
| Malamani, G | 1 |
| Cardellino, G | 1 |
| Pesenti, M | 1 |
| Caiazza, A | 1 |
| Ghisoni, F | 1 |
| Del Prato, C | 1 |
| Innocenti, PF | 1 |
| Ponzanelli, F | 1 |
| Maclean, D | 1 |
| Mitchell, ET | 1 |
| Laing, EM | 1 |
| Gough, KJ | 1 |
| McDevitt, DG | 1 |
| Gostick, NK | 1 |
| Mayhew, SR | 1 |
| Mukerji, D | 1 |
| Bradley, I | 1 |
| Ganvir, P | 1 |
| Shepherd, F | 1 |
| Davis, A | 1 |
| MacKay, D | 1 |
| Hopwood, AM | 1 |
| Cox, JP | 1 |
| Ryan, J | 1 |
| O'Brien, E | 1 |
| O'Malley, K | 1 |
| Miyauchi, T | 1 |
| Ishikawa, T | 1 |
| Tomobe, Y | 1 |
| Yanagisawa, M | 1 |
| Kimura, S | 1 |
| Sugishita, Y | 1 |
| Ito, I | 1 |
| Goto, K | 1 |
| Masaki, T | 1 |
| Moulijn, AC | 1 |
| Castle, CH | 1 |
| Cheung, DG | 1 |
| MacCarthy, EP | 1 |
| Townsend, R | 1 |
| Saunders, E | 1 |
| Davis, WR | 1 |
| Langford, HG | 1 |
| Hongnat, JM | 1 |
| Michaud, F | 1 |
| Landault, C | 1 |
| Baron, JF | 1 |
| Coriat, P | 1 |
| Viars, P | 1 |
| Nishino, H | 1 |
| Fariello, R | 1 |
| Boni, E | 1 |
| Zaninelli, A | 1 |
| Corda, L | 1 |
| Cantalamessa, A | 1 |
| Alicandri, C | 1 |
| Muiesan, G | 1 |
| Rawles, J | 1 |
| Parisi, VM | 2 |
| Salinas, J | 2 |
| Stockmar, EJ | 2 |
| Fujii, S | 1 |
| Kawaguchi, H | 1 |
| Okamoto, H | 1 |
| Saito, H | 1 |
| Togashi, H | 1 |
| Yasuda, H | 1 |
| Di Biase, M | 1 |
| Massari, V | 1 |
| Amodio, G | 1 |
| Favale, S | 1 |
| Rizzon, P | 1 |
| Bélichard, P | 1 |
| Pruneau, D | 2 |
| Rochette, L | 1 |
| Custro, N | 1 |
| Scafidi, V | 1 |
| Gigliottino, R | 1 |
| Patania, I | 1 |
| Bellia, P | 1 |
| di Mare, S | 1 |
| Alessandri, C | 1 |
| Ficara, C | 1 |
| Chaignon, M | 2 |
| Lucsko, M | 2 |
| Rapoud, C | 2 |
| Guédon, J | 2 |
| De Angelis, C | 1 |
| Del Porto, MA | 1 |
| Balsano, F | 1 |
| Karasawa, A | 2 |
| Kubo, K | 2 |
| Shuto, K | 1 |
| Oka, T | 2 |
| Nakamizo, N | 2 |
| Mazzola, C | 1 |
| Colombo, D | 1 |
| Lissoni, F | 1 |
| Serra, G | 1 |
| Turri, DR | 1 |
| Valsecchi, MA | 1 |
| Zanchetti, A | 1 |
| Stojanova, D | 1 |
| Drinovec, J | 1 |
| Marinković, M | 1 |
| Nesović, M | 1 |
| Srbinovski, M | 1 |
| Nikodijević, B | 1 |
| Stalc, A | 1 |
| Naukkarinen, VA | 2 |
| Bellet, B | 1 |
| Pagny, JY | 2 |
| Frère, R | 1 |
| Ménard, D | 1 |
| Valenta de Almeida, L | 1 |
| Farge, D | 1 |
| Guyene, TT | 1 |
| Julien, J | 1 |
| Metra, M | 1 |
| Nodari, S | 1 |
| Nordio, G | 1 |
| Bonandi, L | 1 |
| Raddino, R | 1 |
| Feroldi, P | 1 |
| Dei Cas, L | 1 |
| Visioli, O | 1 |
| Lernhardt, E | 1 |
| Solt-Buzsaki, V | 1 |
| Buttet, C | 1 |
| Cochat, P | 1 |
| Floret, D | 1 |
| Malfroy, J | 1 |
| David, L | 1 |
| Moro, E | 1 |
| Nicolosi, GL | 1 |
| Mayshar, P | 1 |
| Davis, TP | 1 |
| Johnson, DG | 1 |
| Sorkin, EM | 1 |
| Clissold, SP | 1 |
| Agre, K | 1 |
| Ishizaki, T | 3 |
| Aoyagi, K | 2 |
| Tamasawa, N | 1 |
| Lallemand, A | 1 |
| Creytens, G | 1 |
| Saelen, A | 1 |
| Danielsson, A | 1 |
| Bjerle, P | 1 |
| Ek, B | 1 |
| Steen, L | 1 |
| Suhr, O | 1 |
| Karppinen, K | 1 |
| Sarna, S | 1 |
| Lucarini, AR | 1 |
| Tanioka, F | 1 |
| Nagao, N | 1 |
| Nagao, H | 1 |
| Oyama, T | 1 |
| Blanski, L | 1 |
| Langford, H | 1 |
| Smith, SA | 1 |
| Rafiqi, EI | 1 |
| Gardener, EG | 1 |
| Armstrong, C | 1 |
| Garnham, J | 1 |
| Blackwood, R | 1 |
| Montastruc, P | 1 |
| Valet, P | 1 |
| Dang Tran, L | 1 |
| Gaillard, G | 1 |
| Montastruc, JL | 1 |
| Miyashita, H | 1 |
| Tamai, S | 1 |
| Mori, K | 3 |
| Miyazaki, M | 2 |
| Sumioka, T | 1 |
| Yoshiya, I | 2 |
| Enomoto, H | 1 |
| Taguchi, H | 1 |
| Momose, T | 1 |
| Ito, K | 1 |
| Takeya, H | 1 |
| Takazawa, T | 1 |
| Murakami, M | 1 |
| Yogozawa, T | 1 |
| Mizuguchi, T | 1 |
| Kawazoe, T | 1 |
| Yamada, M | 1 |
| Yamazaki, Y | 1 |
| Ido, Y | 1 |
| Honda, M | 1 |
| Manabe, R | 1 |
| Minato, M | 1 |
| Fukuda, N | 1 |
| Izumi, Y | 1 |
| Hatano, M | 1 |
| Charlap, S | 1 |
| Kimmel, B | 1 |
| Laifer, L | 1 |
| Weinberg, P | 1 |
| Singer, M | 1 |
| Lazar, E | 1 |
| Saltzberg, S | 1 |
| Dorsa, F | 1 |
| Kafka, K | 1 |
| Strom, J | 1 |
| Ryman, KS | 2 |
| Kubo, SH | 2 |
| Shaknovich, A | 2 |
| Cody, RJ | 2 |
| Roy, F | 1 |
| Maddalena, G | 1 |
| Bonagura, EC | 1 |
| Petitto, M | 1 |
| Matsukawa, S | 1 |
| Itaya, Y | 1 |
| Kumagai, H | 1 |
| Nievel, JG | 1 |
| Havard, CW | 1 |
| Douglas-Jones, AP | 1 |
| Arai, T | 1 |
| Hatano, Y | 1 |
| Ishida, H | 1 |
| Yanase, O | 1 |
| Hosaka, T | 1 |
| Nanba, K | 1 |
| Tamaki, H | 1 |
| Maezawa, H | 1 |
| Memezawa, H | 1 |
| Sugimoto, S | 1 |
| Nagazumi, A | 1 |
| Terashi, A | 1 |
| Asplund, J | 1 |
| Guerret, M | 1 |
| Frais, MA | 2 |
| Lee, P | 2 |
| Verma, SP | 2 |
| Jackson, N | 2 |
| Biggi, A | 1 |
| Musiari, L | 1 |
| Ravanetti, C | 1 |
| Reynolds, G | 1 |
| Boku, A | 1 |
| Sone, K | 1 |
| Levenson, J | 1 |
| Simon, AC | 1 |
| Bouthier, J | 1 |
| Maarek, BC | 1 |
| Kolloch, R | 1 |
| Stumpe, KO | 1 |
| Overlack, A | 1 |
| Cascone, A | 1 |
| Ferrari, F | 1 |
| Alaimo, A | 1 |
| Daprati, A | 1 |
| Cascone, G | 1 |
| Ohba, T | 1 |
| Tonooka, M | 1 |
| Kawashima, I | 1 |
| Nakayama, S | 1 |
| Yasuhara, H | 1 |
| Sakamoto, K | 1 |
| Rosenkranz, RP | 1 |
| McClelland, DL | 1 |
| Roszkowski, AP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH)[NCT01202864] | 6,000 participants (Actual) | Observational | 2010-08-01 | Completed | |||
| Proper Timing of Control of Hypertension and Outcome in Acute Spontaneous Intracerebral Hemorrhage.[NCT04167644] | 150 participants (Actual) | Observational | 2018-05-01 | Completed | |||
| Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH)-II: A Phase III Randomized Multicenter Clinical Trial of Blood Pressure Reduction for Hypertension in Acute Intracerebral Hemorrhage[NCT01176565] | Phase 3 | 1,000 participants (Actual) | Interventional | 2011-05-15 | Terminated (stopped due to Planned interim analysis: no significant outcome differences between groups) | ||
| A Phase IV, Randomized Trial to Determine the Efficacy and Safety of Cardene Intravenous (I.V.) Versus Labetalol for Management of Hypertensive Emergencies in the Emergency Department Setting[NCT00765648] | Phase 4 | 226 participants (Actual) | Interventional | 2008-10-31 | Completed | ||
| Biologic Mechanisms of Early Exercise After Intracerebral Hemorrhage: a Pilot Randomized Controlled Trial of Cycle Ergometry[NCT04027049] | 40 participants (Anticipated) | Interventional | 2019-03-02 | Recruiting | |||
| Evaluation of Clevidipine in the Perioperative Treatment of Hypertension Assessing Safety Events (With Nitroglycerin as Active Comparator) (ECLIPSE-NTG)[NCT00093886] | Phase 3 | 629 participants (Actual) | Interventional | 2004-04-30 | Completed | ||
| Evaluation of Clevidipine in the Postoperative Treatment of Hypertension Assessing Safety Events (With Nicardipine as Active Comparator) (ECLIPSE-NIC)[NCT00093925] | Phase 3 | 739 participants (Actual) | Interventional | 2004-05-31 | Completed | ||
| Evaluation of Clevidipine in the Perioperative Treatment of Hypertension Assessing Safety Events (With Sodium Nitroprusside as Active Comparator) (ECLISPE-SNP)[NCT00093912] | Phase 3 | 739 participants (Actual) | Interventional | 2004-06-30 | Completed | ||
| Risk Factors for Complications After Carotid Endarterectomy: A Multicenter International Observational Study[NCT03788980] | 10 participants (Actual) | Observational | 2018-04-13 | Terminated (stopped due to Lack of funding and resources) | |||
| Nicardipine Versus Esmolol for Management of Emergence Hypertension After Craniotomy[NCT01951950] | Phase 1 | 40 participants (Actual) | Interventional | 2013-09-30 | Completed | ||
| Influence of Elevated Baseline Serum Creatinine and Body Composition on Acute Kidney Injury in Cardiac Surgery - The InCreAS Trial[NCT02598271] | 200 participants (Actual) | Observational | 2016-10-31 | Completed | |||
| Pre and or Post Operative Blood Pressure Control With Clevidipine (Cleviprexm Medicines Company) in Aortic Aneurysm / Dissection.[NCT01480531] | 0 participants (Actual) | Interventional | 2011-12-31 | Withdrawn (stopped due to We elected to stop this study due to our inability to recruit suitable subjects.) | |||
| Antihypertensive Treatment in Acute Cerebral Hemorrhage (ATACH)[NCT00415610] | Phase 1 | 60 participants (Actual) | Interventional | 2005-07-31 | Completed | ||
| [NCT01041066] | 70 participants (Anticipated) | Interventional | 2009-09-30 | Recruiting | |||
| Efficiency of Intravenous Lidocaine to Reduce Coughing and the Hemodynamic Changes Associated to Tracheal Extubation[NCT03731429] | Phase 4 | 144 participants (Anticipated) | Interventional | 2019-04-05 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The complete count of all subjects who experienced any serious adverse events throughout their participation in the trial was included in this tabulation. Adverse events (AEs) and serious adverse events (SAEs) were assessed by the site investigators for all patients. Potential relatedness to the study treatment was a required reporting element for all adverse events but was not considered in this count. Terminology from the Medical Dictionary for Regulatory Activities (MedDRA) and severity criteria from the Common Terminology Criteria for Adverse Events (CTCAE v. 4.03) were used as a basis for reporting adverse events. Serious adverse events are defined as being fatal, life-threatening, resulting in hospitalization or prolonged hospitalization, resulting in disability or congenital anomaly, or requiring intervention to prevent permanent impairment or damage and were required to be reported promptly. An Independent Oversight Committee (IOC) reviewed and adjudicated adverse event data. (NCT01176565)
Timeframe: From randomization through the 90 day visit (90 ± 14 days per protocol window; up to ± 30 days data is used) or until known death, withdrawal, or loss to follow-up.
| Intervention | Participants (Count of Participants) |
|---|---|
| Standard SBP Reduction Arm | 100 |
| Intensive SBP Reduction Arm | 128 |
Hematoma expansion as determined by serial CT scans: Hematoma expansion was defined as an increase in the volume of intraparenchymal hemorrhage of 33% or greater as measured by a central imaging analyst who was was unaware of the treatment assignments, clinical findings, and time points of image acquisition. The area of the hematoma was delineated by image analysis software with the use of density thresholds on each slice, followed by manual correction. To ensure accuracy and consistency of the readings, images were coded randomly and independently of subject numbers and manual correction was also done without awareness of treatment assignments, clinical findings, or time points of image acquisition. This data point is defined as being present (hematoma expansion of 33% or more was calculated between the baseline scan hematoma volume and the 24 +/- 6 hours hematoma volume measures at data analysis), meaning that hematoma expansion as defined must have occurred or it was not counted. (NCT01176565)
Timeframe: From the baseline head CT to the 24 +/- 6 hours from randomization head CT
| Intervention | Participants (Count of Participants) |
|---|---|
| Standard SBP Reduction Arm | 104 |
| Intensive SBP Reduction Arm | 85 |
Hypotension (abnormally low blood pressure) was the most likely adverse event that could be associated with the study treatment, and is the primary basis (risk) on which neurological deterioration or other untoward effects of the study treatment could occur. It is therefore examined as a numerically-measured occurrence in addition to monitoring patients closely for neurological deterioration or other symptoms. Hypotension, when named as an adverse event, was defined as the syndrome of low blood pressure with SBP < 85 mmHg. Instances of hypotension were to be avoided through close monitoring, and administration of fluid bolus for SBP < 110 mmHg. If hypotension did occur, it was to be reversed as quickly as possible through discontinuation of intravenous nicardipine and intravenous fluid administration, which can be accomplished readily in a variety of settings where patients with intracerebral hemorrhage are routinely housed during early hospitalization. (NCT01176565)
Timeframe: From randomization through 72 hours from randomization
| Intervention | Participants (Count of Participants) |
|---|---|
| Standard SBP Reduction Arm | 3 |
| Intensive SBP Reduction Arm | 6 |
Neurologic deterioration was measured using two scales. The Glasgow Coma Scale (GCS) score measures of level of consciousness in eye, motor, and verbal components. At least one point is given in each category. The scale ranges from 3 to 15, with 3 indicating deep unconsciousness and 15 indicating consciousness is not impaired. The National Institutes of Health Stroke Scale (NIHSS) quantifies neurologic deficits in 11 categories. Level of consciousness, horizontal eye movement, visual fields, facial palsy, movement in each limb, sensation, language & speech, and extinction or inattention on one side of the body are tested. Scores range from 0 to 42, with 0 indicating normal function and higher scores indicating greater deficit severity. Neurological status was checked per ICU standards through 24 hours, recommended as hourly GCS and full assessment every 2 hours. NIHSS assessment at baseline and 24 +/- 3 hours was pre-specified. Assessments were added for suspected neurological change. (NCT01176565)
Timeframe: From randomization through the 24-hour treatment period
| Intervention | Participants (Count of Participants) |
|---|---|
| Standard SBP Reduction Arm | 40 |
| Intensive SBP Reduction Arm | 55 |
Adverse events (AEs) and serious adverse events (SAEs) were assessed by the site investigators for all patients, including for their potential relatedness to the study treatment. An Independent Oversight Committee (IOC) reviewed and adjudicated all adverse event data. The 72-hours-from-randomization time window was considered the most likely time frame during which treatment-related adverse events or serious adverse events would be observed. Terminology from the Medical Dictionary for Regulatory Activities (MedDRA) and severity criteria from the Common Terminology Criteria for Adverse Events (CTCAE v. 4.03) were used as a basis for reporting adverse events. Serious adverse events are defined as being fatal, life-threatening, resulting in hospitalization or prolonged hospitalization, resulting in disability or congenital anomaly, or requiring intervention to prevent permanent impairment or damage and were required to be reported promptly. (NCT01176565)
Timeframe: From randomization through 72 hours (3 days)
| Intervention | Participants (Count of Participants) |
|---|---|
| Standard SBP Reduction Arm | 6 |
| Intensive SBP Reduction Arm | 8 |
The primary outcome was death or disability, defined by modified Rankin scale (mRS) of 4-6 at 90 days following treatment. The modified Rankin Scale score ranges from 0, indicating no symptoms, to 6, indicating death. A score of 4 indicates moderately severe disability including the inability to walk or attend to one's own bodily needs. A score of 5 indicates severe disability; bedridden, incontinent, and requiring constant nursing care. To score a 3 or lower on the mRS, a person must at least be able to walk without the assistance of another person. We chose the mRS because of its high inter-observer reliability, superiority to other indices, and consistency with previous trials in patients with ICH. Reliability was further increased by use of a structured interview template and by requiring mRS assessors to pass a certification test. Persons conducting the 90-day mRS assessment were to be unaware of the treatment arm or clinical course of the patients they assessed. (NCT01176565)
Timeframe: 90 days (± 14 days per protocol window; up to ± 30 days data is used) from randomization
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Death or disability at 90 days (mRS = 4 - 6) | Known death at or before 90 days | |
| Intensive SBP Reduction Arm | 186 | 33 |
| Standard SBP Reduction Arm | 181 | 34 |
Standardized scales developed by the EuroQol Research Foundation were used as a secondary outcome measure in addition to the mRS scale score. The EQ-5D is a simple, standardized non-disease-specific instrument for describing and valuating health-related quality of life. The EQ-5D-3L questionnaire consists of 5 questions in 5 different domains and allows for responses from 1 (the best outcome) to 3 (the worst outcome) in each of five categories (mobility, self-care, usual activities, pain/discomfort, and anxiety/depression). Total scores range from 5 to 15, with lower scores indicating better quality of life and a higher score indicating a worse quality of life. A second component of EuroQol outcome measurements is a printed 20 cm visual analogue scale (EQ VAS) that appears somewhat like a thermometer, on which a score from 0 (worst imaginable health state or death) to 100 (best imaginable health state) is marked by the patient (or, when necessary, their proxy) with the scale in view. (NCT01176565)
Timeframe: 90 days (± 14 days per protocol window; up to ± 30 days data is used) from randomization
| Intervention | units on a scale (Median) | |
|---|---|---|
| EQ-5D utility scale questionnaire | EQ VAS (visual analog scale) | |
| Intensive SBP Reduction Arm | 0.7 | 62.5 |
| Standard SBP Reduction Arm | 0.7 | 70 |
Calculated as the mean (± standard deviation) number of titrations over 30 minutes for each treatment group (NCT00765648)
Timeframe: 30 minutes
| Intervention | number of titrations (Mean) |
|---|---|
| Nicardipine | 2.2 |
| Labetalol | 1.3 |
Median number of hours from hospital admission until Emergency Department(ED)disposition (NCT00765648)
Timeframe: 6 hours
| Intervention | hours (Median) |
|---|---|
| Nicardipine | 4.6 |
| Labetalol | 4.6 |
Percentage of subjects achieving a pre-defined target systolic blood pressure (BP) range defined as a systolic blood pressure that is within +/- 20 mmHg of the target as established by the investigator. (NCT00765648)
Timeframe: 30 minutes after initiation of therapy
| Intervention | percentage of participants (Number) |
|---|---|
| Nicardipine | 91.7 |
| Labetalol | 82.5 |
The percent of subjects requiring the use of intravenous rescue medications (NCT00765648)
Timeframe: 6 hours
| Intervention | percentage of participants (Number) |
|---|---|
| Nicardipine | 15.5 |
| Labetalol | 22.4 |
The median transition time (in hours) to oral medication (NCT00765648)
Timeframe: 6 hours
| Intervention | hours (Median) |
|---|---|
| Nicardipine | 4.9 |
| Labetalol | 6.4 |
Treatment failure is defined as admission to the hospital or observation unit for BP management (NCT00765648)
Timeframe: 6 hours
| Intervention | percentage of participants (Number) |
|---|---|
| Nicardipine | 43.1 |
| Labetalol | 37.4 |
(NCT01951950)
Timeframe: 1 hour postoperatively
| Intervention | participants (Number) |
|---|---|
| Nicardipine | 1 |
| Esmolol | 11 |
Neurological status was monitored quantitatively and independently of other adverse events using two scales. The Glasgow Coma Scale (GCS) score measures level of consciousness in eye, motor, and verbal components. At least one point is given in each category. The scale ranges from 3 to 15, with 3 indicating deep unconsciousness and 15 indicating consciousness is not impaired. The National Institutes of Health Stroke Scale (NIHSS) quantifies neurologic deficits in 11 categories. Level of consciousness, horizontal eye movements, visual fields, facial palsy, movement in each limb, sensation, language and speech, and extinction or inattention on one side of the body are tested. Scores range from 0 to 42; 0 indicates normal function and higher scores indicate greater deficit severity. (NCT00415610)
Timeframe: within the first 72 hours of treatment initiation
| Intervention | participants (Number) |
|---|---|
| Tier 1 | 1 |
| Tier 2 | 2 |
| Tier 3 | 4 |
Serious adverse events were ascertained by site investigators using FDA-defined guidelines, defined as any untoward clinical events having been fatal, life-threatening, resulting in new or prolonged hospitalization, resulting in disability or congenital anomaly, or requiring intervention to prevent permanent impairment or damage. Subjects were followed closely from randomization through 90 days. The initial 72-hour period was chosen as the most meaningful time period for which to examine SAEs likely to be related to the acute safety of the study treatment. (NCT00415610)
Timeframe: from treatment initiation through 72 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| Tier 1 | 0 |
| Tier 2 | 1 |
| Tier 3 | 3 |
Feasibility of treatment was assessed by whether SBP reduction and maintenance within the respective target range was achieved (treatment success) or not (treatment failure), and secondarily by whether a significant difference between treatment arms was achieved. Treatment failure was defined based on the observed hourly hourly minimum SBP remaining greater than the upper limit of the target range for 2 consecutive hours after initiation of nicardipine infusion. Spontaneous decline of SBP below the lower limit of the specific tier was not considered treatment failure as all such declines were asymptomatic.The lower number in the more intensive treatment groups reflects in part the greater challenge of rapidly lowering systolic blood pressure to a more intensive (lower) range, as a higher number of treatment failures as pre-defined by meeting the SBP range goal within 3 hours of symptom onset in this group predictably occurred. (NCT00415610)
Timeframe: Within 3 hours of symptom onset and sustained through 18-24 hours.
| Intervention | participants (Number) | ||
|---|---|---|---|
| Meeting Criteria of initial SBP > 170 mmHg | Number treated within 3 hours of symptom onset | Treatment Failure, SBP not in range by 2 hours | |
| Tier 1 | 18 | 7 | 0 |
| Tier 2 | 20 | 5 | 0 |
| Tier 3 | 22 | 6 | 9 |
The ability to maintain the Specified Systolic Blood Pressure Range for the 18-24 Hour Period without Neurological Deterioration or Side Effects (NCT00415610)
Timeframe: 3 months
| Intervention | participants (Number) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| N with SAE within 72 hours | N with neurologic deterioration within 24 hours | N with symptomatic hematoma expansion | N with asymptomatic hematoma expansion | N with in-hospital mortality | N with 3-month mortality | N with 1-month favorable outcome, mRS 0-2 | N missing for 1-month outcome assessment | N with 3-month favorable outcome, mRS 0-2 | N missing for 3-month outcome assessment | |
| Tier 1 | 0 | 1 | 0 | 6 | 2 | 3 | 4 | 3 | 8 | 3 |
| Tier 2 | 1 | 2 | 1 | 2 | 1 | 2 | 6 | 3 | 9 | 4 |
| Tier 3 | 3 | 4 | 4 | 3 | 1 | 5 | 4 | 2 | 7 | 2 |
33 reviews available for nicardipine and Hypertension
| Article | Year |
|---|---|
Comparison of Intravenous Antihypertensives on Blood Pressure Control in Acute Neurovascular Emergencies: A Systematic Review.
Topics: Antihypertensive Agents; Blood Pressure; Emergencies; Humans; Hypertension; Labetalol; Nicardipine; | 2022 |
Comparison between clevidipine and nicardipine in cerebrovascular diseases: A systematic review and meta-analysis.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cerebrovascular Disorders; | 2023 |
Hypertensive Emergency: Parenteral Antihypertensives and Population Data.
Topics: Antihypertensive Agents; Emergencies; Humans; Hypertension; Hypertensive Encephalopathy; Labetalol; | 2023 |
Sodium nitroprusside versus nicardipine for hypertension management after surgery: A systematic review and meta-analysis.
Topics: Adult; Aged; Arterial Pressure; Blood Pressure; Cardiac Surgical Procedures; Female; Hemodynamics; H | 2020 |
Hypertension Management in Emergency Departments.
Topics: Acute Disease; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihyper | 2020 |
Sodium Nitroprusside as a Hyperinflation Drug and Therapeutic Alternatives.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Cost Control; Drug Costs; Humans; Hypertension; I | 2018 |
The optimal treatment of severe hypertension in pregnancy: update of the role of nicardipine.
Topics: Antihypertensive Agents; Female; Humans; Hypertension; Hypotension; Infant, Newborn; Labetalol; Nica | 2014 |
Perioperative hypertension management.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Enalaprilat; Fenoldopam; Hemodynamics; Humans; | 2008 |
Use of injectable nicardipine for neurovascular indications.
Topics: Antihypertensive Agents; Cerebral Hemorrhage; Humans; Hypertension; Injections; Meta-Analysis as Top | 2009 |
A systematic review of nicardipine vs labetalol for the management of hypertensive crises.
Topics: Acute Disease; Antihypertensive Agents; Humans; Hypertension; Labetalol; Nicardipine | 2012 |
Hypertensive emergencies: an update.
Topics: Acute Disease; Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Critical Care; | 2011 |
Antioxidant effects and anti-elastase activity of the calcium antagonist nicardipine on activated human and rabbit neutrophils--a potential antiatherosclerotic property of calcium antagonists?
Topics: Animals; Antioxidants; Calcium Channel Blockers; Humans; Hypertension; Neutrophil Activation; Nicard | 2002 |
Clinical features and management of selected hypertensive emergencies.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Emergency Treatment; Fenoldopam; Humans; Hyper | 2004 |
Intravenous nicardipine: its use in the short-term treatment of hypertension and various other indications.
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Humans; Hypertension; Injections, | 2006 |
Pathophysiology and medical management of systemic hypertension in preeclampsia.
Topics: Adrenergic beta-Antagonists; Aspirin; Calcium; Calcium Channel Blockers; Cerebral Hemorrhage; Female | 2006 |
A review of calcium channel antagonists in the treatment of pediatric hypertension.
Topics: Amiodarone; Calcium Channel Blockers; Child; Felodipine; Humans; Hypertension; Isradipine; Nicardipi | 2006 |
Calcium entry blockers as vasodilators in man.
Topics: Calcium Channel Blockers; Humans; Hypertension; Nicardipine; Nifedipine; Nitroprusside; Vascular Res | 1984 |
Nicardipine and treatment of cerebrovascular diseases with particular reference to hypertension-related disorders.
Topics: Aged; Animals; Brain; Brain Ischemia; Calcium Channels; Cerebrovascular Disorders; Humans; Hypertens | 1995 |
Cerebral vasospasm.
Topics: Aneurysm, Ruptured; Blood Pressure; Blood Volume; Brain Ischemia; Catheterization; Cerebral Infarcti | 1993 |
Therapeutic advances in the treatment of left ventricular hypertrophy.
Topics: Animals; Antihypertensive Agents; Heart Failure; Hemodynamics; Humans; Hypertension; Hypertrophy, Le | 1993 |
Management of hypertensive urgencies and emergencies.
Topics: Administration, Oral; Antihypertensive Agents; Emergencies; Enalaprilat; Female; Humans; Hydralazine | 1995 |
Concomitant diseases in elderly hypertensives: the position of nicardipine.
Topics: Aging; Calcium Channel Blockers; Cerebrovascular Disorders; Humans; Hypertension; Kidney Diseases; N | 1996 |
The diagnosis and management of hypertensive crises.
Topics: Antihypertensive Agents; Aortic Aneurysm; Aortic Dissection; Clonidine; Diazoxide; Enalaprilat; Fema | 2000 |
[Intravenous nicardipine: a new calcium antagonist for perioperative use].
Topics: Adenosine Triphosphate; Calcium; Calcium Channel Blockers; Drug Interactions; Electrocardiography; H | 2001 |
Management of hypertensive emergencies: changing therapeutic options.
Topics: Emergencies; Humans; Hydralazine; Hypertension; Labetalol; Nicardipine; Nitroprusside | 1991 |
[Use of intravenous nicardipine for the diagnosis of renovascular hypertension].
Topics: Adult; Aged; Clinical Protocols; Female; Humans; Hypertension; Hypertension, Renovascular; Injection | 1991 |
Cardiovascular effects of nicardipine.
Topics: Animals; Arrhythmias, Cardiac; Cardiovascular System; Coronary Disease; Heart; Heart Failure; Hemody | 1990 |
Clinical considerations for the use of intravenous nicardipine in the treatment of postoperative hypertension.
Topics: Anesthesia, General; Calcium Channel Blockers; Humans; Hypertension; Injections, Intravenous; Nicard | 1990 |
Nicardipine: another calcium antagonist.
Topics: Angina Pectoris; Humans; Hypertension; Nicardipine | 1989 |
Antihypertensive therapy in the geriatric patient. I: A review of the role of calcium channel blockers.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Humans; Hyperte | 1989 |
New therapeutic modalities in hypertension: focus on a new calcium antagonist-nicardipine.
Topics: Humans; Hypertension; Nicardipine | 1989 |
Nicardipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in the treatment of angina pectoris, hypertension and related cardiovascular disorders.
Topics: Angina Pectoris; Cardiovascular Diseases; Humans; Hypertension; Kinetics; Nicardipine | 1987 |
Nicardipine for systemic hypertension: effects on blood pressure and target organ function.
Topics: Aged; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Hypertensi | 1987 |
178 trials available for nicardipine and Hypertension
| Article | Year |
|---|---|
Initial antihypertensive agent effects on acute blood pressure after intracerebral haemorrhage.
Topics: Antihypertensive Agents; Blood Pressure; Cerebral Hemorrhage; Humans; Hydralazine; Hypertension; Lab | 2022 |
A prospective evaluation of labetalol versus nicardipine for blood pressure management in patients with acute stroke.
Topics: Aged; Antihypertensive Agents; APACHE; Blood Pressure; Female; Hospital Mortality; Humans; Hypertens | 2013 |
Impact of initial blood pressure on antihypertensive response in patients with acute hypertension.
Topics: Acute Disease; Antihypertensive Agents; Blood Pressure; Creatinine; Emergency Service, Hospital; Hum | 2014 |
The management of acute hypertension in patients with renal dysfunction: labetalol or nicardipine?
Topics: Acute Disease; Antihypertensive Agents; Comorbidity; Double-Blind Method; Female; Humans; Hypertensi | 2014 |
Nicardipine is superior to esmolol for the management of postcraniotomy emergence hypertension: a randomized open-label study.
Topics: Aged; Anesthesia Recovery Period; Antihypertensive Agents; Brain Neoplasms; Craniotomy; Female; Huma | 2015 |
Characteristics of patients that do not initially respond to intravenous antihypertensives in the emergency department: subanalysis of the CLUE trial.
Topics: Antihypertensive Agents; Emergency Service, Hospital; Emergency Treatment; Female; Humans; Hypertens | 2015 |
Ketanserin versus dihydralazine for the treatment of severe hypertension in early-onset preeclampsia: a double blind randomized controlled trial.
Topics: Adult; Antihypertensive Agents; Dihydralazine; Double-Blind Method; Female; Gestational Age; Hospita | 2015 |
Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage.
Topics: Aged; Antihypertensive Agents; Cerebral Hemorrhage; Female; Glasgow Coma Scale; Humans; Hypertension | 2016 |
Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage.
Topics: Aged; Antihypertensive Agents; Cerebral Hemorrhage; Female; Glasgow Coma Scale; Humans; Hypertension | 2016 |
Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage.
Topics: Aged; Antihypertensive Agents; Cerebral Hemorrhage; Female; Glasgow Coma Scale; Humans; Hypertension | 2016 |
Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage.
Topics: Aged; Antihypertensive Agents; Cerebral Hemorrhage; Female; Glasgow Coma Scale; Humans; Hypertension | 2016 |
Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage.
Topics: Aged; Antihypertensive Agents; Cerebral Hemorrhage; Female; Glasgow Coma Scale; Humans; Hypertension | 2016 |
Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage.
Topics: Aged; Antihypertensive Agents; Cerebral Hemorrhage; Female; Glasgow Coma Scale; Humans; Hypertension | 2016 |
Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage.
Topics: Aged; Antihypertensive Agents; Cerebral Hemorrhage; Female; Glasgow Coma Scale; Humans; Hypertension | 2016 |
Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage.
Topics: Aged; Antihypertensive Agents; Cerebral Hemorrhage; Female; Glasgow Coma Scale; Humans; Hypertension | 2016 |
Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage.
Topics: Aged; Antihypertensive Agents; Cerebral Hemorrhage; Female; Glasgow Coma Scale; Humans; Hypertension | 2016 |
Prospective randomized comparison of safety and efficacy of nicardipine and nitroprusside drip for control of hypertension in the neurosurgical intensive care unit.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Critical Care; Female; Humans; Hypertension; Infusions, | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2008 |
Management of hypertensive emergencies in acute brain disease: evaluation of the treatment effects of intravenous nicardipine on cerebral oxygenation.
Topics: Acute Disease; Adult; Aged; Antihypertensive Agents; Blood Pressure; Brain; Brain Injuries; Cerebral | 2008 |
Cardioprotective effect of an L/N-type calcium channel blocker in patients with hypertensive heart disease.
Topics: Adult; Aged; Calcium Channel Blockers; Dihydropyridines; Female; Heart; Humans; Hypertension; Hypert | 2009 |
Effect of systolic blood pressure reduction on hematoma expansion, perihematomal edema, and 3-month outcome among patients with intracerebral hemorrhage: results from the antihypertensive treatment of acute cerebral hemorrhage study.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Brain; Brain Edema; Cerebral Arteries; Dose-Re | 2010 |
Effect of systolic blood pressure reduction on hematoma expansion, perihematomal edema, and 3-month outcome among patients with intracerebral hemorrhage: results from the antihypertensive treatment of acute cerebral hemorrhage study.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Brain; Brain Edema; Cerebral Arteries; Dose-Re | 2010 |
Effect of systolic blood pressure reduction on hematoma expansion, perihematomal edema, and 3-month outcome among patients with intracerebral hemorrhage: results from the antihypertensive treatment of acute cerebral hemorrhage study.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Brain; Brain Edema; Cerebral Arteries; Dose-Re | 2010 |
Effect of systolic blood pressure reduction on hematoma expansion, perihematomal edema, and 3-month outcome among patients with intracerebral hemorrhage: results from the antihypertensive treatment of acute cerebral hemorrhage study.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Brain; Brain Edema; Cerebral Arteries; Dose-Re | 2010 |
CLUE: a randomized comparative effectiveness trial of IV nicardipine versus labetalol use in the emergency department.
Topics: Acute Disease; Adult; Aged; Antihypertensive Agents; Blood Pressure; Emergency Service, Hospital; Fe | 2011 |
Intravenous labetalol compared with intravenous nicardipine in the management of hypertension in critically ill patients.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Critical Illness; Female; Hospital Charges; Humans; H | 2012 |
Comparative prophylactic and therapeutic effects of intravenous labetalol 0.4 mg/kg and nicardipine 20 μg/kg on hypertensive responses to endotracheal intubation in patients undergoing elective surgeries with general anesthesia: a prospective, randomized,
Topics: Adult; Anesthesia, General; Antihypertensive Agents; Dose-Response Relationship, Drug; Double-Blind | 2012 |
Short-term treatment of severe hypertension of pregnancy: prospective comparison of nicardipine and labetalol.
Topics: Adult; Antihypertensive Agents; Female; Humans; Hypertension; Labetalol; Nicardipine; Pre-Eclampsia; | 2002 |
Effects of four antihypertensive monotherapies on cardiac mass and function in hypertensive patients with left ventricular hypertrophy: randomized prospective study.
Topics: Adult; Aged; Antihypertensive Agents; Chlorthalidone; Croatia; Echocardiography; Female; Heart Ventr | 2002 |
Effects of nicardipine on coronary, vertebral and renal arterial flows in patients with essential hypertension.
Topics: Aged; Blood Circulation; Blood Flow Velocity; Calcium Channel Blockers; Cerebrovascular Circulation; | 2003 |
Effects of nicardipine and clonidine on cognitive functions and electroencephalography in hypertensive patients.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clonidine; Cognition; Cross | 2002 |
Randomized, comparative, double-blind study of amlodipine vs. nicardipine as a treatment of isolated systolic hypertension in the elderly.
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitor | 2002 |
Effects of nicardipine and diltiazem on the bispectral index and 95% spectral edge frequency.
Topics: Adult; Aged; Analysis of Variance; Anesthesia, Intravenous; Antihypertensive Agents; Calcium Channel | 2003 |
The use of nicardipine for electroconvulsive therapy: a dose-ranging study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Calcium Channe | 2005 |
Long-term anti-hypertensive therapy with benidipine improves arterial stiffness over blood pressure lowering.
Topics: Adult; Antihypertensive Agents; Arteries; Blood Pressure; Calcium Channel Blockers; Diabetes Complic | 2005 |
[A comparison of the effect of oral captopril and nicardipine in hypertensive crisis].
Topics: Administration, Oral; Aged; Antihypertensive Agents; Captopril; Female; Humans; Hypertension; Male; | 2008 |
[Treatment of arterial hypertension in the aged with a calcium antagonist: nicardipine].
Topics: Aged; Calcium Channel Blockers; Double-Blind Method; Drug Evaluation; Female; Humans; Hypertension; | 1984 |
Blockade of slow calcium channels and regulation of circulatory pressor responses in uncomplicated hypertension.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Humans; Hypertens | 1983 |
[Comparison of vascular effects of magnesium sulfate and nicardipine during extracorporeal circulation].
Topics: Aged; Anesthesia, General; Antihypertensive Agents; Blood Pressure; Cardiac Surgical Procedures; Ext | 1995 |
Effects of calcium channel blockers on circulatory response to tracheal intubation in hypertensive patients: nicardipine versus diltiazem.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Diltiazem; Female; Heart Rate; Humans; Hypert | 1995 |
Intravenous nicardipine for the treatment of severe hypertension. A dose-titration infusion to therapeutic response.
Topics: Adult; Aged; Female; Humans; Hypertension; Infusions, Intravenous; Male; Middle Aged; Nicardipine | 1995 |
Diltiazem vs. nicardipine on ambulatory and exercise blood pressure and on peripheral hemodynamics.
Topics: Adult; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cross-Over Studies; Delayed-Action Pre | 1995 |
Evaluation of the efficacy and safety of oral nicardipine in treatment of urgent hypertension: a multicenter, randomized, double-blind, parallel, placebo-controlled clinical trial.
Topics: Administration, Oral; Adult; Analysis of Variance; Blood Pressure; Double-Blind Method; Emergencies; | 1995 |
Assessment of blood pressure during naproxen therapy in hypertensive patients treated with nicardipine.
Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hypertens | 1995 |
[Endocrine effects of nicardipine on intraoperative hypertension under droperidol-fentanyl-ketamine (DFK) anesthesia].
Topics: Adult; Aged; Aldosterone; Anesthesia, Intravenous; Atrial Natriuretic Factor; Catecholamines; Droper | 1995 |
Treatment of elderly hypertensives in Japan: National Intervention Cooperative Study in Elderly Hypertensives. The National Intervention Cooperative Study Group.
Topics: Aged; Cardiovascular Diseases; Cerebrovascular Disorders; Double-Blind Method; Female; Humans; Hyper | 1994 |
A comparison of intravenous nicardipine and sodium nitroprusside in the immediate treatment of severe hypertension.
Topics: Adult; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Hypertension; I | 1994 |
Comparison of the effects of captopril and nicardipine on insulin sensitivity and thrombotic profile in patients with hypertension and android obesity. CaptISM Study Group. Captopril Insulin Sensitivity Multicenter Study Group.
Topics: Adult; Aged; Antigens; Blood Pressure; Captopril; Double-Blind Method; Factor VII; Female; Fibrinoge | 1994 |
Nicardipine versus metoprolol in the treatment of hypertension during pregnancy: a randomized comparative trial.
Topics: Adult; Birth Weight; Blood Pressure; Cesarean Section; Drug Administration Schedule; Female; Humans; | 1994 |
Comparison of effects of nicardipine and trichlormethiazide on insulin sensitivity in hypertensive patients.
Topics: Adult; Blood Pressure; Electrolytes; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hypert | 1994 |
Noninvasive assessment of the direct action of oral nifedipine and nicardipine on left ventricular contractile state in patients with systemic hypertension: importance of reflex sympathetic responses.
Topics: Adrenergic beta-Antagonists; Adult; Double-Blind Method; Echocardiography, Doppler; Heart Ventricles | 1993 |
Effects of nicardipine on intimal-medial thickness and arterial distensibility in hypertensive patients. Preliminary results after 6 months.
Topics: Carotid Artery, Common; Delayed-Action Preparations; Drug Administration Schedule; Female; Follow-Up | 1993 |
[Antihypertensive action of nicardipine retard in 24 hours and its effect on stress].
Topics: Adult; Aged; Blood Pressure Monitors; Delayed-Action Preparations; Double-Blind Method; Exercise Tes | 1993 |
[Slow-release nicardipine in the treatment of arterial hypertension: comparative study vs. an ACE inhibitor].
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Delayed-Action Preparations; Drug Evaluation; | 1993 |
Clinical pharmacology of nicardipine in liver transplant patients.
Topics: Adult; Female; Humans; Hypertension; Infusions, Intravenous; Liver; Liver Circulation; Liver Transpl | 1993 |
Sustained-release nicardipine in mild-to-moderate hypertension.
Topics: Adult; Aged; Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Hyper | 1993 |
Nicardipine or propranolol combined with hydrochlorothiazide in patients with essential hypertension.
Topics: Adult; Aged; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hy | 1993 |
[Studies of efficacy and tolerance in elderly patients].
Topics: Aged; Drug Tolerance; Humans; Hypertension; Nicardipine | 1993 |
Long-term effects of a converting enzyme inhibitor and a calcium channel blocker on urinary albumin excretion in patients with essential hypertension.
Topics: Albuminuria; Blood Pressure; Enalapril; Humans; Hypertension; Middle Aged; Morbidity; Nicardipine; P | 1993 |
Nicardipine treatment of hypertension during pregnancy.
Topics: Administration, Oral; Adult; Blood Pressure; Female; Fetus; Heart Rate; Heart Rate, Fetal; Humans; H | 1993 |
Comparison of the efficacy and metabolic effects of nicardipine and hydrochlorothiazide in hypertensive black men and women.
Topics: Adult; Aged; Black People; Blood Glucose; Cholesterol; Creatinine; Double-Blind Method; Female; Home | 1993 |
[Nicardipine attenuates the sympathetic reflex of orthostatism: do dihydropyridine-sensitive calcium channels regulate noradrenaline release?].
Topics: Adult; Calcium Channel Blockers; Calcium Channels; Cross-Over Studies; Double-Blind Method; Female; | 1992 |
Determination of (+)- and (-)-nicardipine concentrations in human serum and their correlation with the antihypertensive effect after oral administration of racemic nicardipine.
Topics: Administration, Oral; Adult; Aged; Antihypertensive Agents; Blood Pressure; Chromatography, High Pre | 1995 |
Effects of nicardipine on blood cyclosporine levels in renal transplant patients.
Topics: Adult; Azathioprine; Calcium Channel Blockers; Creatinine; Cyclosporine; Female; Humans; Hypertensio | 1996 |
Comparison of antihypertensive effects of nicardipine with nitroglycerin for perioperative hypertension.
Topics: Aged; Antihypertensive Agents; Calcium Channel Blockers; Female; Hemodynamics; Humans; Hypertension; | 1995 |
Calcium channel blockers versus ACE inhibitors as antihypertensives in polycystic kidney disease.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel B | 1996 |
Comparison between a bid and a tid regimen: improved compliance with no improved antihypertensive effect. The EOL Research Group.
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Female; Humans; Hypertension; Mal | 1996 |
[Relation between plasma renin level and antihypertensive response to nicardipine].
Topics: Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Female; Humans; Hyp | 1995 |
Effects of benazepril and nicardipine on microalbuminuria in normotensive and hypertensive patients with diabetes.
Topics: Adult; Aged; Albuminuria; Antihypertensive Agents; Benzazepines; Diabetes Mellitus, Type 1; Diabetes | 1996 |
Clinical trial of nicardipine in treatment of mild to moderate hypertension.
Topics: Adult; Aged; Blood Pressure Determination; Calcium Channel Blockers; Female; Humans; Hypertension; M | 1995 |
Effects of nifedipine and nicardipine on regional cerebral blood flow distribution in patients with arterial hypertension.
Topics: Adult; Aged; Blood Pressure; Brain Ischemia; Calcium Channel Blockers; Cerebrovascular Circulation; | 1996 |
Intravenous nicardipine in hypertensive preterm infants.
Topics: Calcium Channel Blockers; Humans; Hypertension; Infant, Newborn; Infant, Premature; Infant, Prematur | 1997 |
Both a calcium antagonist and ACE inhibitor reverse hypertrophy in hypertension but a calcium antagonist also depresses contractility.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Captopril; Double-B | 1997 |
Optimal dose of nicardipine for maintenance of hemodynamic stability after tracheal intubation and skin incision.
Topics: Adult; Anesthesia; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dermatologic S | 1997 |
Calcium channel blockers attenuate cardiovascular responses to tracheal extubation in hypertensive patients.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Female; Heart | 1998 |
[Exclusive use of calcium channel blockers and cardioselective beta-blockers in the pre- and per-operative management of pheochromocytomas. 70 cases].
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Calciu | 1998 |
Effect of antihypertensive therapy on aortic distensibility in patients with essential hypertension: comparison with trichlormethiazide, nicardipine and alacepril.
Topics: Age Factors; Antihypertensive Agents; Aorta; Blood Pressure; Captopril; Echocardiography; Elasticity | 1999 |
Randomized double-blind comparison of a calcium antagonist and a diuretic in elderly hypertensives. National Intervention Cooperative Study in Elderly Hypertensives Study Group.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Diuretics; Double-Blind Method; Female; Humans; Hype | 1999 |
Effect of long-term treatment with antihypertensive drugs on quality of life of elderly patients with hypertension: a double-blind comparative study between a calcium antagonist and a diuretic. NICS-EH Study Group. National Intervention Cooperative Study
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Diuretics; Double-Blind Method; Female; Follow-Up St | 2000 |
Intravenous nicardipine as a first-line antihypertensive drug in neonates.
Topics: Analysis of Variance; Antihypertensive Agents; Female; Humans; Hypertension; Infant, Newborn; Infant | 2000 |
A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Anesth | 2000 |
A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Anesth | 2000 |
A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Anesth | 2000 |
A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Anesth | 2000 |
Nicardipine versus nitroprusside for breakthrough hypertension following carotid endarterectomy.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Endarterectomy, Carotid; Female; | 2001 |
Tolerability and safety of a calcium channel blocker in comparison with a diuretic in the treatment of elderly patients with hypertension: secondary analysis of the NICS-EH.
Topics: Aged; Calcium Channel Blockers; Disease-Free Survival; Diuretics; Follow-Up Studies; Humans; Hyperte | 2001 |
Combined administration of diltiazem and nicardipine attenuates hypertensive responses to emergence and extubation.
Topics: Aged; Anesthesia; Anesthesia Recovery Period; Antihypertensive Agents; Blood Pressure; Diltiazem; Dr | 2002 |
[Comparison of nicardipine and isradipine in hypertension following coronary artery bypass graft].
Topics: Aged; Antihypertensive Agents; Calcium Channel Blockers; Coronary Artery Bypass; Female; Hemodynamic | 2002 |
[Comparison of nicardipine and nifedipine in treatment of Chinese senile hypertension placebo-control, double-blind, randomized and crossover study].
Topics: Aged; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Nicardip | 1992 |
Effect of manidipine, a new calcium antagonist, on intrarenal hemodynamics in essential hypertension.
Topics: Blood Pressure; Blood Proteins; Calcium Channel Blockers; Dihydropyridines; Female; Glomerular Filtr | 1992 |
Large artery compliance in essential hypertension. Effects of calcium antagonism and beta-blocking.
Topics: Adrenergic beta-Antagonists; Adult; Arteries; Atenolol; Blood Pressure; Calcium Channel Blockers; Co | 1992 |
The influence of nicardipine in type 2 diabetic patients with slight hypertension.
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Hypertension; Male; Mid | 1990 |
The effects of nicardipine in elderly hypertensive patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Humans; Hypertension; Italy; Male; Middle Aged; | 1990 |
A comparative study of nicardipine and pindolol as second-line treatments in essential hypertension.
Topics: Adult; Aged; Blood Pressure; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; N | 1992 |
Effects of calcium channel blockers on cardiovascular responses to smoking in normotensive and hypertensive smokers.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Female; Heart Rate; Hemodynami | 1992 |
Treatment of intraoperative hypertension with enflurane, nicardipine, or human atrial natriuretic peptide: haemodynamic and renal effects.
Topics: Absorption; Adult; Aged; Anesthesia, Inhalation; Atrial Natriuretic Factor; Blood Pressure; Creatini | 1992 |
Postoperative hypertension: a multicenter, prospective, randomized comparison between intravenous nicardipine and sodium nitroprusside.
Topics: Aged; Analysis of Variance; Cardiac Surgical Procedures; Female; Hemodynamics; Humans; Hypertension; | 1992 |
[Efficacy and tolerability of nicardipine retard and captopril in hypertension in the aged. Results of a multicenter study].
Topics: Aged; Aged, 80 and over; Blood Pressure; Captopril; Delayed-Action Preparations; Drug Tolerance; Fem | 1992 |
Comparison of sustained-release formulations of nicardipine and verapamil for mild to moderate systemic hypertension.
Topics: Delayed-Action Preparations; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hype | 1992 |
Serum concentration-effect relationship of (+/-)-nicardipine and nifedipine in elderly hypertensive patients.
Topics: Aged; Aged, 80 and over; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Fema | 1992 |
Dose requirement and effect of nicardipine on lipid profile in mild to moderate essential hypertensives.
Topics: Adult; Aged; Blood Pressure; Cholesterol; Female; Heart Rate; Humans; Hypertension; Lipids; Lipoprot | 1992 |
Nicardipine does not cause deterioration of glucose homoeostasis in man: a placebo controlled study in elderly hypertensives with and without diabetes mellitus.
Topics: Aged; Arginine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose Toler | 1992 |
Effects of sustained-release nicardipine on regression of left ventricular hypertrophy in systemic hypertension.
Topics: Aldosterone; Blood Pressure; Cardiomegaly; Delayed-Action Preparations; Double-Blind Method; Echocar | 1992 |
[The efficacy of nicardipine in treating arterial hypertension in elderly patients. A multicenter outpatient study].
Topics: Aged; Aged, 80 and over; Ambulatory Care; Blood Pressure; Drug Evaluation; Drug Tolerance; Female; H | 1992 |
Nicardipine retard in the therapy of elderly diabetic hypertensives: final report of observational study.
Topics: Aged; Aging; Analysis of Variance; Blood Glucose; Blood Pressure; Delayed-Action Preparations; Diabe | 1992 |
Ambulatory blood pressure monitoring for the assessment of nicardipine as a third drug in severe essential hypertension.
Topics: Adult; Aged; Ambulatory Care; Blood Pressure Determination; Capsules; Captopril; Delayed-Action Prep | 1992 |
Nitrendipine 20 mg once daily versus nicardipine slow release 40 mg twice daily in mild essential hypertension: evaluation by 24-hour ambulatory blood pressure monitoring.
Topics: Adult; Blood Pressure; Delayed-Action Preparations; Humans; Hypertension; Male; Middle Aged; Monitor | 1992 |
Comparison of nicardipine and sodium nitroprusside in the treatment of hypertension after coronary bypass surgery (a pilot study).
Topics: Aged; Coronary Artery Bypass; Hemodynamics; Humans; Hypertension; Middle Aged; Nicardipine; Nitropru | 1992 |
Calcium entry blockade and adrenergic vascular reactivity in hypertensives: differences between nicardipine and diltiazem.
Topics: Adrenergic alpha-Antagonists; Adult; Biological Transport; Blood Vessels; Calcium Channel Blockers; | 1991 |
Comparative effects on blood pressure and regional hemodynamics of nicardipine and captopril.
Topics: Adult; Blood Pressure; Captopril; Cardiac Output; Female; Heart Rate; Hemodynamics; Humans; Hyperten | 1991 |
[Efficacy and tolerance of LA 50 mg nicardipine in hypertensive athletes].
Topics: Adult; Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Drug Tolerance; Exercise Te | 1991 |
Nicardipine and nifedipine in the treatment of essential arterial hypertension.
Topics: Adult; Blood Pressure; Double-Blind Method; Electrocardiography; Female; Heart Rate; Humans; Hyperte | 1991 |
Analysis of advancing age on the response to nicardipine among 467 adult hypertensive patients.
Topics: Aging; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Nicardi | 1991 |
Comparison of nicardipine and sodium nitroprusside in the treatment of paroxysmal hypertension following aortocoronary bypass surgery.
Topics: Arrhythmias, Cardiac; Blood Pressure; Blood Transfusion; Cardiac Output; Coronary Artery Bypass; Fem | 1991 |
Double-blind, randomized comparative study of the antihypertensive effect of nicardipine slow-release and nifedipine slow-release in hypertensive patients with coronary heart disease.
Topics: Blood Pressure Monitors; Delayed-Action Preparations; Double-Blind Method; Female; Heart Rate; Human | 1991 |
Nicardipine as antihypertensive monotherapy: positive effects on quality of life.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Metho | 1991 |
[Use of intravenous nicardipine for the diagnosis of renovascular hypertension].
Topics: Adult; Aged; Clinical Protocols; Female; Humans; Hypertension; Hypertension, Renovascular; Injection | 1991 |
Nicardipine sustained release in hypertension.
Topics: Adult; Aged; Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Female; Heart Rate; H | 1991 |
Effect of a calcium-entry blocker, nicardipine, on intrarenal hemodynamics in essential hypertension.
Topics: Diet, Sodium-Restricted; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney Glomerulus | 1991 |
Efficacy and safety of intravenous nicardipine in the control of postoperative hypertension. IV Nicardipine Study Group.
Topics: Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Hemodynamics; Humans; Hypertension; Inf | 1991 |
Treatment of hypertensive urgencies with oral nifedipine, nicardipine, and captopril.
Topics: Administration, Sublingual; Blood Pressure; Captopril; Emergencies; Female; Humans; Hypertension; Ma | 1991 |
[Use of calcium antagonist nicardipine in hypertension in ambulatory conditions].
Topics: Adult; Aged; Ambulatory Care; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Nicar | 1991 |
Adrenergic response to nicardipine in the management of postoperative hypertension.
Topics: Aged; Aged, 80 and over; Blood Pressure; Double-Blind Method; Heart Rate; Humans; Hypertension; Infu | 1990 |
Effects of nicardipine on left ventricular dimensions and hemodynamics in systemic hypertension.
Topics: Clinical Trials as Topic; Echocardiography; Echocardiography, Doppler; Female; Hemodynamics; Humans; | 1990 |
The effects of nicardipine on sodium and calcium metabolism in hypertensive patients: a chronic study.
Topics: Administration, Oral; Adult; Aged; Aldosterone; Calcium; Double-Blind Method; Female; Humans; Hypert | 1990 |
Nicardipine infusion for postoperative hypertension after surgery of the head and neck.
Topics: Blood Pressure; Double-Blind Method; Head; Humans; Hypertension; Infusions, Intravenous; Neck; Nicar | 1990 |
Postoperative hypertension: a prospective, placebo-controlled, randomized, double-blind trial, with intravenous nicardipine hydrochloride.
Topics: Double-Blind Method; Hemodynamics; Humans; Hypertension; Infusions, Intravenous; Nicardipine; Placeb | 1990 |
Hypertension and arrhythmias: effects of slow-release nicardipine vs chlorthalidone: a double-blind crossover study.
Topics: Adult; Arrhythmias, Cardiac; Chlorthalidone; Delayed-Action Preparations; Double-Blind Method; Elect | 1990 |
[Blood pressure monitoring in aged hypertensive patients treated with sustained-release nicardipine or nifedipine].
Topics: Aged; Aged, 80 and over; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Male; Ni | 1990 |
Efficacy of nicardipine slow release (SR) on hypertension, potassium balance and plasma aldosterone in idiopathic aldosteronism.
Topics: Administration, Oral; Adult; Aldosterone; Blood Pressure; Delayed-Action Preparations; Female; Human | 1990 |
Nicardipine versus placebo for the treatment of postoperative hypertension.
Topics: Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Hypertension; Injections, In | 1990 |
Nicardipine and propranolol in the treatment of hypertension: similar antihypertensive but dissimilar hemodynamic actions.
Topics: Antihypertensive Agents; Exercise Test; Hemodynamics; Humans; Hypertension; Middle Aged; Nicardipine | 1990 |
Pharmacokinetics, pharmacodynamics, and minimum effective clinical dose of intravenous nicardipine.
Topics: Analysis of Variance; Blood Pressure; Clinical Protocols; Double-Blind Method; Female; Humans; Hyper | 1990 |
Effects on casual and 24-h ambulatory blood pressure of slow-release nicardipine and chlorthalidone in arterial essential hypertension: double-blind, crossover study.
Topics: Adult; Blood Pressure; Blood Pressure Determination; Chlorthalidone; Delayed-Action Preparations; Do | 1990 |
Intravenous nicardipine hydrochloride: treatment of patients with severe hypertension.
Topics: Blood Pressure; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Injections, Intraven | 1990 |
An evaluation of the pharmacodynamics and pharmacokinetics of nicardipine combined with enalapril in essential hypertension.
Topics: Adult; Aged; Blood Pressure; Drug Therapy, Combination; Enalapril; Epinephrine; Female; Heart Rate; | 1987 |
Comparison of intravenous nicardipine and nitroglycerin to control systemic hypertension after coronary artery bypass grafting.
Topics: Coronary Artery Bypass; Drug Evaluation; Female; Hemodynamics; Humans; Hypertension; Infusions, Intr | 1989 |
[Effect of a calcium inhibitor, nicardipine, on aldosterone secretion in primary hyperaldosteronism].
Topics: Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Hypera | 1989 |
Intravenous nicardipine for treatment of intraoperative hypertension during abdominal surgery.
Topics: Abdomen; Blood Pressure; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Injections, | 1989 |
Effects of nicardipine on left ventricular hemodynamic patterns in systemic hypertension.
Topics: Adult; Blood Pressure; Cardiomegaly; Double-Blind Method; Echocardiography; Female; Humans; Hyperten | 1989 |
Left ventricular mass changes with nicardipine therapy in essential hypertension.
Topics: Adult; Aged; Blood Pressure; Cardiomegaly; Echocardiography; Female; Heart Ventricles; Humans; Hyper | 1989 |
Comparison of the renal effects of angiotensin converting enzyme inhibitor and calcium antagonist in hypertensive type 2 (non-insulin-dependent) diabetic patients with microalbuminuria: a randomised controlled trial.
Topics: Aged; Albuminuria; Blood Pressure; Blood Proteins; Clinical Trials as Topic; Diabetes Mellitus, Type | 1989 |
Regional hemodynamic effects of slow-release nicardipine in elderly patients with hypertension: evaluation by a new ultrasound technique.
Topics: Aged; Aged, 80 and over; Blood Flow Velocity; Blood Pressure; Brachial Artery; Carotid Arteries; Del | 1989 |
Nicardipine monotherapy in ambulatory elderly patients with hypertension.
Topics: Aged; Blood Pressure; Electrocardiography; Female; Heart Rate; Humans; Hypertension; Male; Multicent | 1989 |
Nicardipine in elderly patients with hypertension: a review of experience in France.
Topics: Aged; Aged, 80 and over; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Huma | 1989 |
Nicardipine and propranolol in the treatment of essential hypertension.
Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hyperte | 1989 |
Nicardipine and hydrochlorothiazide in essential hypertension.
Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Exercise; Female; Heart | 1989 |
Antihypertensive therapy in the geriatric patient. I: A review of the role of calcium channel blockers.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Humans; Hyperte | 1989 |
[Antihypertensive effect and tolerability of slow-release nicardipine].
Topics: Adult; Aged; Clinical Trials as Topic; Delayed-Action Preparations; Drug Tolerance; Female; Humans; | 1989 |
Antihypertensive effect of slow-release nicardipine. A placebo-controlled cross-over study.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Met | 1989 |
Comparison of the efficacy and acceptability of nicardipine and propranolol, alone and in combination, in mild to moderate hypertension.
Topics: Adult; Aged; Blood Chemical Analysis; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; | 1989 |
A randomised comparative trial of nicardipine versus amiloride and hydrochlorothiazide in mild to moderate hypertension. A report from the General Practitioner Hypertension Study Group.
Topics: Adolescent; Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Drug Combinations; Hum | 1989 |
The effect of slow-release nicardipine on ambulatory and clinic blood pressure in mild hypertension.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Met | 1989 |
Antihypertensive and anti-ischemic effects of nicardipine and nitroprusside in patients undergoing coronary artery bypass grafting.
Topics: Aged; Clinical Trials as Topic; Coronary Artery Bypass; Coronary Disease; Electrocardiography; Fenta | 1989 |
Intravenous nicardipine in severe systemic hypertension.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hyperten | 1989 |
Long-term systemic arterial blood pressure control with nicardipine.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Administration Sche | 1989 |
Intravenous nicardipine for the treatment of severe hypertension. A double-blind, placebo-controlled multicenter trial.
Topics: Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Headache; Humans; | 1989 |
[Peridural lumbar anesthesia in hypertensives: the effect of immediate preanesthetic treatment with nicardipine].
Topics: Anesthesia, Epidural; Humans; Hypertension; Nicardipine; Preanesthetic Medication; Randomized Contro | 1989 |
Evaluation of a long acting formulation of nicardipine in hypertension by clinic and home recorded blood pressures and Doppler aortovelography.
Topics: Blood Pressure; Heart Rate; Humans; Hypertension; Nicardipine; Random Allocation | 1989 |
Enalapril in essential hypertension: the comparative effects of additional placebo, nicardipine and chlorthalidone.
Topics: Acetylcholinesterase; Blood Pressure; Catecholamines; Chlorthalidone; Clinical Trials as Topic; Doub | 1987 |
[Effects of chronic administration of several calcium antagonists on pituitary release of TSH].
Topics: Adult; Atenolol; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Humans; Hyper | 1987 |
Effect of nicardipine on angiotensin II platelet content.
Topics: Aged; Angiotensin II; Blood Platelets; Clinical Trials as Topic; Female; Humans; Hypertension; Male; | 1988 |
Antihypertensive and hemodynamic effects of slow-release nicardipine.
Topics: Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Heart Ra | 1988 |
Antihypertensive efficacy of nicardipine-based treatment in patients of different age and in patients with isolated systolic hypertension.
Topics: Age Factors; Aged; Humans; Hypertension; Italy; Middle Aged; Multicenter Studies as Topic; Nicardipi | 1988 |
Nicardipine versus nifedipine: multicentre controlled trial in essential hypertension.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Dose-Response Relations | 1988 |
Serum lipid changes in patients with mild to moderate essential hypertension taking nicardipine and propranolol.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypertension; Lipids; Male; Mi | 1988 |
[Double-blind evaluation of slow-release nicardipine using different methods of blood pressure measurement. Predictive value of the acute response to intravenous nicardipine].
Topics: Adult; Aged; Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Humans; Hypertension; | 1987 |
A randomized double-blind crossover study of nicardipine and nifedipine in patients with angina pectoris and concomitant essential hypertension.
Topics: Adult; Angina Pectoris; Blood Pressure; Double-Blind Method; Heart; Humans; Hypertension; Male; Midd | 1988 |
Dose response to hydrochlorothiazide in hypertensives receiving a calcium channel blocker.
Topics: Blood Glucose; Blood Pressure; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; | 1988 |
Antihypertensive effects of parenteral nicardipine alone and in combination with captopril.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Captopril; Drug Therapy, Combination; Heart Rate; | 1987 |
Nicardipine for systemic hypertension: effects on blood pressure and target organ function.
Topics: Aged; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Hypertensi | 1987 |
An overview of the safety and efficacy of nicardipine in clinical trials.
Topics: Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; | 1987 |
Multiple oral doses of nicardipine, a calcium-entry blocker: effects on renal function, plasma renin activity, and aldosterone concentration in mild-to-moderate essential hypertension.
Topics: Adult; Aldosterone; Clinical Trials as Topic; Female; Glomerular Filtration Rate; Hemodynamics; Huma | 1987 |
[Treatment of arterial hypertension with a new calcium antagonist: nicardipine].
Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Clinical Trials as Topic; Drug Administration Schedu | 1987 |
Comparative effects of nicardipine hydrochloride and hydrochlorothiazide in the treatment of mild to moderate hypertension: a double-blind parallel study.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hyp | 1986 |
Nicardipine in the treatment of essential hypertension controlled 6-month-study comparing nicardipine with propranolol at rest and during exercise.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Electrocardiography; Female; Humans; Hyperten | 1987 |
Comparison of nicardipine and propranolol in the treatment of mild and moderate hypertension.
Topics: Adult; Blood Pressure; Body Weight; Cholesterol; Clinical Trials as Topic; Double-Blind Method; Huma | 1987 |
Haemodynamic (systemic and renal) and humoral interactions between nicardipine and domperidone in hypertensives.
Topics: Adult; Aldosterone; Domperidone; Drug Interactions; Female; Glomerular Filtration Rate; Heart Rate; | 1987 |
Evaluation of slow release nicardipine in essential hypertension by casual and ambulatory blood pressure measurements. Effects of acute versus chronic administration.
Topics: Administration, Sublingual; Adult; Aged; Blood Pressure; Blood Pressure Determination; Delayed-Actio | 1987 |
Comparison of the efficacy of nicardipine, a new calcium channel blocker, with nifedipine in the treatment of mild to moderate essential hypertension.
Topics: Adult; Aged; Blood Pressure; Body Weight; Female; Heart Rate; Humans; Hypertension; Male; Middle Age | 1987 |
[Age and efficacy of calcium entry blocker in essential hypertension--double blind trial using nicardipine].
Topics: Adult; Age Factors; Aged; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; F | 1986 |
[A comparison between nicardipine hydrochloride (YC-93) and trimethaphan camsylate for treatment of acute hypertension during surgery. A double blind study in 12 institutions].
Topics: Acute Disease; Adolescent; Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Double-Bl | 1986 |
[Antihypertensive effects of nicardipine hydrochloride (YC-93) on patients with hypertension during neuroleptanesthesia].
Topics: Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Female; Humans; Hypertension; Intrao | 1986 |
[Result of randomized comparative clinical study of nicardipine hydrochloride and trimethaphan camsylate on control of blood pressure during surgery].
Topics: Aged; Antihypertensive Agents; Clinical Trials as Topic; Female; Humans; Hypertension; Intraoperativ | 1986 |
Renal effects of nicardipine, a calcium entry blocker, in hypertensive type II diabetic patients with nephropathy.
Topics: Adult; Albuminuria; Clinical Trials as Topic; Diabetic Nephropathies; Female; Glomerular Filtration | 1986 |
Twice-daily nicardipine in the treatment of essential hypertension.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Admini | 1986 |
Comparison of concomitant nicardipine hydrochloride and propranolol with propranolol alone in patients with essential hypertension.
Topics: Adult; Aged; Aged, 80 and over; Double-Blind Method; Drug Therapy, Combination; Drug Tolerance; Fema | 1987 |
Nicardipine hydrochloride in essential hypertension--a controlled study.
Topics: Adult; Age Factors; Calcium Channel Blockers; Clinical Trials as Topic; Female; Humans; Hypertension | 1985 |
Effect of nicardipine in elderly hypertensive patients.
Topics: Age Factors; Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Female; Heart | 1985 |
Anti-hypertensive dose-response effects of nicardipine in stable essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clinical Trials as T | 1985 |
Renal effects of nicardipine in patients with mild-to-moderate essential hypertension.
Topics: Adult; Calcium Channel Blockers; Female; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertens | 1986 |
Blood pressure, heart rate and A-V conduction responses to nicardipine in hypertensive patients receiving atenolol.
Topics: Adult; Atenolol; Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combination; Female; Heart | 1985 |
274 other studies available for nicardipine and Hypertension
| Article | Year |
|---|---|
Comparison of premade clevidipine and pharmacy-prepared nicardipine in time to goal systolic blood pressure in acute cerebrovascular accident.
Topics: Antihypertensive Agents; Blood Pressure; Goals; Humans; Hypertension; Nicardipine; Pharmacy; Pyridin | 2022 |
Comparative Study of Clevidipine to Nicardipine for Perioperative Hypertension in Patients Undergoing Cardiac Surgery.
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiac Surgical Procedures; Huma | 2023 |
Comparison of Clevidipine and Nicardipine for Acute Blood Pressure Reduction in Hemorrhagic Stroke.
Topics: Acute Kidney Injury; Adult; Antihypertensive Agents; Blood Pressure; Bradycardia; Hematoma; Hemorrha | 2022 |
Nicardipine Is a Safe, Efficacious, and Cost-Effective Antihypertensive for Neonates and Young Infants Undergoing Cardiac Surgery.
Topics: Antihypertensive Agents; Blood Pressure; Cardiac Surgical Procedures; Cost-Benefit Analysis; Humans; | 2022 |
Nicardipine for treating severe antepartum hypertension during pregnancy: Nine years of experience in more than 800 women.
Topics: Antihypertensive Agents; Blood Pressure; Cesarean Section; Female; Humans; Hypertension; Hypotension | 2022 |
Use of continuous infusion of nicardipine to control persistent postpartum hypertension: A retrospective study.
Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Hypertension; Labetalol; Nicar | 2022 |
Utility of nicardipine in the management of hypertensive crises in adults with reduced ejection fractions.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Bradycardia; Heart Failure; Humans; Hypertension; Hy | 2024 |
Delay to Tissue Plasminogen Activator in Hypertensive Stroke Patients: An Analysis of Delay Duration Across Agents.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Drug Administration Schedule; Female; Fibrinolytic Ag | 2020 |
Clevidipine use after first-line treatment failure for perioperative hypertension in neurosurgical patients: A single-center experience.
Topics: Blood Pressure; Calcium Channel Blockers; Female; Humans; Hypertension; Intraoperative Complications | 2020 |
Early Initiation of Oral Antihypertensives Reduces Intensive Care Unit Stay and Hospital Cost for Patients with Hypertensive Intracerebral Hemorrhage.
Topics: Administration, Oral; Aged; Antihypertensive Agents; Early Medical Intervention; Female; Functional | 2020 |
Efficacy of low-dose nicardipine for emergent treatment of severe postpartum hypertension in maternal intensive care units: An observational study.
Topics: Administration, Intravenous; Adult; Blood Pressure; Calcium Channel Blockers; Female; Humans; Hypert | 2020 |
Coronavirus disease 2019 in pregnancy: early lessons.
Topics: Acute Kidney Injury; Adult; Anesthesia, General; Anti-Bacterial Agents; Antihypertensive Agents; Azi | 2020 |
Nicardipine: When high dose nitrates fail in treating heart failure.
Topics: Administration, Intravenous; Blood Pressure; Calcium Channel Blockers; Female; Humans; Hypertension; | 2021 |
Stability study of a compounded oral solution of nicardipine for the treatment of hypertension in children.
Topics: Administration, Oral; Antihypertensive Agents; Child; Chromatography, High Pressure Liquid; Drug Com | 2021 |
Intra-arterial versus oscillometric blood pressure measurements in women with severe peripartum hypertension undergoing urgent treatment with nicardipine: An observational study.
Topics: Adult; Antihypertensive Agents; Arterial Pressure; Atrial Pressure; Blood Pressure; Blood Pressure D | 2021 |
Blood Pressure Control in Acute Stroke: Labetalol or Nicardipine?
Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pre | 2021 |
Posterior reversible encephalopathy syndrome (PRES) in a patient with moyamoya disease: A case report.
Topics: Adult; Antihypertensive Agents; Brain; Brain Edema; Diagnosis, Differential; Humans; Hypertension; M | 2021 |
Labetalol Use Is Associated With Increased In-Hospital Infection Compared With Nicardipine Use in Intracerebral Hemorrhage.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Cerebral Hemorrhage; Cross Infect | 2017 |
Use of Nicardipine After Cardiac Operations Is Safe in Children Regardless of Age.
Topics: Age Factors; Calcium Channel Blockers; Cardiac Surgical Procedures; Child; Child, Preschool; Female; | 2018 |
Continuous-Infusion Labetalol vs Nicardipine for Hypertension Management in Stroke Patients.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calci | 2018 |
Reduction of Nicardipine-Related Phlebitis in Patients with Acute Stroke by Diluting Its Concentration.
Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antihypertensive Agents; Female; Humans; Hyper | 2018 |
Comparison of Nicardipine with Clevidipine in the Management of Hypertension in Acute Cerebrovascular Diseases.
Topics: Acute Disease; Aged; Antihypertensive Agents; Cerebrovascular Disorders; Cross-Sectional Studies; Fe | 2018 |
Blood Pressure-Attained Analysis of ATACH 2 Trial.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Cerebral Hemorrhage; Cl | 2018 |
Blood Pressure-Attained Analysis of ATACH 2 Trial.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Cerebral Hemorrhage; Cl | 2018 |
Blood Pressure-Attained Analysis of ATACH 2 Trial.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Cerebral Hemorrhage; Cl | 2018 |
Blood Pressure-Attained Analysis of ATACH 2 Trial.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Cerebral Hemorrhage; Cl | 2018 |
A case of posterior reversible encephalopathy syndrome associated with sepsis.
Topics: Anticonvulsants; Antihypertensive Agents; Brain; Diabetic Ketoacidosis; Humans; Hypertension; Leveti | 2018 |
Early Achievement of Blood Pressure Lowering and Hematoma Growth in Acute Intracerebral Hemorrhage: Stroke Acute Management with Urgent Risk-Factor Assessment and Improvement-Intracerebral Hemorrhage Study.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Feasibility Studies; Female; Hematoma; Humans; Hypert | 2018 |
Without Warning: Scleroderma Renal Crisis.
Topics: Acute Kidney Injury; Amlodipine; Antihypertensive Agents; Humans; Hypertension; Labetalol; Lisinopri | 2019 |
Relationship between the administration of nicardipine hydrochloride and the development of delirium in patients on mechanical ventilation.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Calcium Channel Blockers; Delirium; Female; | 2018 |
Nicardipine Associated Risk of Short-Term Mortality in Critically Ill Patients with Ischemic Stroke.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Brain Ischemia; Critical Illness; Databases, Factual; | 2019 |
Are admission systolic blood pressures predictive of outcomes in patients with spontaneous intracerebral haemorrhage after aggressive blood pressure management?
Topics: Aged; Antihypertensive Agents; Blood Pressure; Cerebral Hemorrhage; Female; Humans; Hypertension; In | 2015 |
A cost analysis of the impact of a new intravenous antihypertensive in managing perioperative blood pressure during cardiac surgery.
Topics: Administration, Intravenous; Aged; Antihypertensive Agents; Blood Pressure; Cardiac Surgical Procedu | 2014 |
Pharmacokinetic drug-drug interaction of calcium channel blockers with cyclosporine in hematopoietic stem cell transplant children.
Topics: Adolescent; Amlodipine; Calcium Channel Blockers; Child; Child, Preschool; Cyclosporine; Dihydropyri | 2014 |
Hemodynamic effects of intravenous nicardipine in severely pre-eclamptic women with a hypertensive crisis.
Topics: Administration, Intravenous; Adolescent; Adult; Antihypertensive Agents; Cardiac Output; Echocardiog | 2016 |
Involvement of CYP 3A5 In the Interaction Between Tacrolimus and Nicardipine: A Case Report.
Topics: Antihypertensive Agents; Biotransformation; Calcium Channel Blockers; Cytochrome P-450 CYP3A; Cytoch | 2015 |
Bradycardia caused by intravenous nicardipine in an elderly patient with acute ischemic infarct.
Topics: Aged; Antihypertensive Agents; Bradycardia; Brain Ischemia; Calcium Channel Blockers; Humans; Hypert | 2016 |
Prolonged Cardiac Dysfunction After Intraparenchymal Hemorrhage and Neurogenic Stunned Myocardium.
Topics: Adult; Anesthesia, General; Cerebral Hemorrhage; Emergency Service, Hospital; Heart; Hemangioma, Cav | 2016 |
There Is More to Postcraniotomy Emergence Hypertension Than Simply Blood Pressure Control-Why Nicardipine May Not Be the Drug of Choice.
Topics: Antihypertensive Agents; Craniotomy; Female; Humans; Hypertension; Male; Nicardipine; Postoperative | 2015 |
In Response.
Topics: Antihypertensive Agents; Craniotomy; Female; Humans; Hypertension; Male; Nicardipine; Postoperative | 2015 |
Time to Blood Pressure Control Before Thrombolytic Therapy in Patients With Acute Ischemic Stroke: Comparison of Labetalol, Nicardipine, and Hydralazine.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Brain Ischemia; Female; Fib | 2015 |
Mechanisms of the antihypertensive effects of Nigella sativa oil in L-NAME-induced hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Heme Oxygenase (Decyclizing); Hypertension; Male; | 2015 |
Nicardipine for Hypertension Following Aortic Coarctectomy or Superior Cavopulmonary Anastomosis.
Topics: Aortic Coarctation; Blood Pressure; Calcium Channel Blockers; Child; Child, Preschool; Female; Heart | 2016 |
The utility of bolus intravenous nicardipine for hypertensive emergencies in the ED.
Topics: Aged, 80 and over; Antihypertensive Agents; Emergencies; Emergency Service, Hospital; Humans; Hypert | 2016 |
Pearls & Oy-sters: Iatrogenic relative hypotension leading to diffuse internal borderzone infarctions and coma.
Topics: Adult; Antihypertensive Agents; Brain Infarction; Coma; Diffusion Magnetic Resonance Imaging; Fatal | 2016 |
Risk Factors of Nicardipine-Related Phlebitis in Acute Stroke Patients.
Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antihypertensive Agents; Dose-Response Relatio | 2016 |
A comparison between evacuation from the scene and interhospital transportation using a helicopter for subarachnoid hemorrhage.
Topics: Aged; Aged, 80 and over; Air Ambulances; Ambulances; Antihypertensive Agents; Blood Pressure; Female | 2017 |
Clevidipine Versus Nicardipine for Acute Blood Pressure Reduction in a Neuroscience Intensive Care Population.
Topics: Aged; Calcium Channel Blockers; Critical Care; Female; Humans; Hypertension; Male; Middle Aged; Nerv | 2017 |
Woman with Hypertension and Seizure.
Topics: Anticonvulsants; Antihypertensive Agents; Diagnosis, Differential; Female; Humans; Hypertension; Mag | 2017 |
Intensive lowering of blood pressure in the acute phase of intracranial haemorrhage.
Topics: Acute Disease; Antihypertensive Agents; Cerebral Hemorrhage; Female; Glasgow Coma Scale; Humans; Hyp | 2017 |
[Hypertension in the absence of renal involvement during childhood Henoch-Schönlein purpura].
Topics: Antihypertensive Agents; Child; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Humans; | 2008 |
Late and fatal deterioration of an intracerebral hemorrhage attributable to the onset of a high titer of acquired factor V inhibitor.
Topics: Aged; Anti-Ulcer Agents; Antihypertensive Agents; Cerebral Hemorrhage; Factor V; Factor V Deficiency | 2008 |
Spontaneous rupture of Achilles tendon and Cushing's disease. Case report.
Topics: Absorptiometry, Photon; Achilles Tendon; Adrenalectomy; Adult; Diabetes Complications; Hormones; Hum | 2008 |
[Reversible posterior leukoencephalopathy syndrome with the neuroradiological abnormalities predominantly in the brainstem].
Topics: Antihypertensive Agents; Brain Stem; Diagnosis, Differential; Humans; Hypertension; Infusions, Intra | 2008 |
Conservative treatment of ruptured vertebrobasilar dissecting aneurysm.
Topics: Adjuvants, Anesthesia; Aged; Aged, 80 and over; Antihypertensive Agents; Basilar Artery; Bed Rest; B | 2008 |
[Anesthetic management of undiagnosed pheochromocytoma: a case report].
Topics: Adrenal Gland Neoplasms; Anesthesia; Antihypertensive Agents; Humans; Hypertension; Intraoperative C | 2008 |
Clevidipine in the treatment of perioperative hypertension: assessing safety events in the ECLIPSE trials.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Calcium Channel Blockers; Cardiac S | 2009 |
A new intravenous calcium channel blocker option to treat acute elevations in blood pressure.
Topics: Acute Disease; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Humans; Hypertensi | 2009 |
Massive polyuria after kidney transplantation.
Topics: Adolescent; Antihypertensive Agents; Humans; Hyperglycemia; Hypertension; Hyponatremia; Kidney Failu | 2010 |
Safety and efficacy of intravenous labetalol for hypertensive crisis in infants and small children.
Topics: Analysis of Variance; Antihypertensive Agents; Chi-Square Distribution; Female; Humans; Hypertension | 2011 |
Ectopic ACTH syndrome revealed as severe hypokalemia and persistent hypertension during the perioperative period: a case report.
Topics: ACTH Syndrome, Ectopic; Adjuvants, Anesthesia; Anesthesia; Anesthetics, Intravenous; Blood Gas Analy | 2011 |
A case of reversible posterior leukoencephalopathy syndrome in a patient on peritoneal dialysis.
Topics: Adult; Diffusion Magnetic Resonance Imaging; Humans; Hypertension; Magnetic Resonance Imaging; Male; | 2010 |
Preventive effect of aggressive blood pressure lowering on hematoma enlargement in patients with ultra-acute intracerebral hemorrhage.
Topics: Acute Disease; Aged; Antihypertensive Agents; Cerebral Arteries; Cerebral Hemorrhage; Female; Hemato | 2010 |
Interaction between tacrolimus and intravenous nicardipine in the treatment of post-kidney transplant hypertension at pediatric hospitals.
Topics: Adolescent; Adult; Antihypertensive Agents; Child; Child, Preschool; Databases, Factual; Female; Hum | 2011 |
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. BET 1. Nicardipine hydrochloride for hypertensive crisis in patients with aortic dissection.
Topics: Aortic Aneurysm; Aortic Dissection; Critical Illness; Emergency Medicine; Emergency Service, Hospita | 2011 |
Angioedema associated with dihydropyridine calcium-channel blockers in a child with Burkitt lymphoma.
Topics: Amlodipine; Angioedema; Burkitt Lymphoma; Calcium Channel Blockers; Child; Humans; Hypertension; Mac | 2011 |
Association of serum glucose concentrations during acute hospitalization with hematoma expansion, perihematomal edema, and three month outcome among patients with intracerebral hemorrhage.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Glucose; Brain Edema; Cerebral Hemorrhage; D | 2011 |
Dutch guideline for the management of hypertensive crisis -- 2010 revision.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calc | 2011 |
Risk of tacrolimus toxicity in CYP3A5 nonexpressors treated with intravenous nicardipine after kidney transplantation.
Topics: Adolescent; Antihypertensive Agents; Child; Cytochrome P-450 CYP3A; Female; Humans; Hypertension; Im | 2012 |
Retrospective evaluation of nicardipine versus labetalol for blood pressure control in aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Critical Care; Female; Humans; Hypertension; L | 2012 |
Effectiveness and safety of nicardipine and labetalol infusion for blood pressure management in patients with intracerebral and subarachnoid hemorrhage.
Topics: Adult; Aged; Antihypertensive Agents; Cerebral Hemorrhage; Cohort Studies; Drug Therapy, Combination | 2013 |
[Medical therapy for intracranial hemorrhage: update blood pressure management for prevention and acute treatment].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Cerebral Hemorrhage; Humans; Hypertension; Mid | 2012 |
Protection against ischemia and improvement of cerebral blood flow in genetically hypertensive rats by chronic pretreatment with an angiotensin II AT1 antagonist.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensiv | 2002 |
Nicardipine to control neonatal hypertension during extracorporeal membrane oxygen support.
Topics: Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Extracorporeal Membrane O | 2003 |
[Therapeutics indications and prognosis of eclampsia at Dakar University Teaching Hospital].
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Antihypertensive Agents; Eclampsia; Female; Gestati | 2003 |
Treatment with nicardipine protects brain in an animal model of hypertension-induced damage.
Topics: Animals; Antihypertensive Agents; Astrocytes; Blood Pressure; Dementia, Vascular; Disease Models, An | 2004 |
Pheochromocytoma unmasked by amisulpride and tiapride.
Topics: Adult; Amisulpride; Antipsychotic Agents; Calcium Channel Blockers; Headache; Humans; Hypertension; | 2005 |
Comparison of the direct negative dromotropic effect of a new calcium channel blocker, cilnidipine, with that of nicardipine.
Topics: Aged; Analysis of Variance; Animals; Atrial Fibrillation; Bradycardia; Calcium Channel Blockers; Dih | 2005 |
Effects of neck exposure to 5.5 mT static magnetic field on pharmacologically modulated blood pressure in conscious rabbits.
Topics: Animals; Baroreflex; Blood Pressure; Bradycardia; Calcium Channel Blockers; Carotid Sinus; Conscious | 2005 |
Elevated plasma nitric oxide metabolites in hypertension: synergistic vasodepressor effects of a static magnetic field and nicardipine in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Calcium Channels; Heart Rate; Hypertension; Magnetics; Nicardipine; Nitric | 2006 |
Treatment of acute hypertension in patients with intracerebral hemorrhage using American Heart Association guidelines.
Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Cerebral Hemorrhage; Drug Tolerance; Female; Humans; | 2006 |
Blood pressure control after intracerebral hemorrhage: have we reached the target?
Topics: Acute Disease; Antihypertensive Agents; Cerebral Hemorrhage; Humans; Hypertension; Nicardipine | 2006 |
Improvement of donor myocardial function after treatment of autonomic storm during brain death.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Brain Death; Cohort Studies; Creat | 2006 |
The comparative effects of intravenous nicardipine and prostaglandin E1 on the cerebral pial arteriolar constriction seen after unclamping of an aortic cross-clamp in rabbits.
Topics: Alprostadil; Animals; Aorta; Arteries; Blood Pressure; Cerebrovascular Circulation; Hypertension; Hy | 2007 |
Induction of hepatic cytochrome P450 isoforms by nicardipine at therapeutic doses in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Calcium Channel Blockers; Dose-Resp | 2007 |
Azelnidipine attenuates cardiovascular and sympathetic responses to air-jet stress in genetically hypertensive rats.
Topics: Administration, Oral; Animals; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; C | 2007 |
Symptomatic autoregulatory failure in acute ischemic stroke.
Topics: Acute Disease; Antihypertensive Agents; Blood Pressure; Brain; Brain Ischemia; Cerebral Arteries; Ce | 2007 |
A comparison of nicardipine and labetalol for acute hypertension management following stroke.
Topics: Acute Disease; Aged; Antihypertensive Agents; APACHE; Blood Pressure; Brain Ischemia; Cerebral Hemor | 2008 |
Ischemic colitis following colonoscopy in an elderly patient on cardiovascular medication.
Topics: Aged, 80 and over; Arrhythmias, Cardiac; Cardiovascular Agents; Colitis, Ischemic; Colonic Neoplasms | 2007 |
Nicardipine after aortic valve replacement and coronary artery bypass graft: case study.
Topics: Aged; Antihypertensive Agents; Aortic Valve; Aortic Valve Stenosis; Coronary Artery Bypass; Heart Va | 2007 |
Intraoperative antihypertensive therapy in a previously normotensive patient: case study.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Endarterectomy, Carotid; Humans; Hypertension; Intrao | 2007 |
Pressor response to beta-blocking drugs.
Topics: Adrenergic beta-Antagonists; Atenolol; Blood Pressure; Female; Humans; Hypertension; Isoproterenol; | 1984 |
Use of calcium antagonists as monotherapy in the management of hypertension.
Topics: Calcium; Calcium Channel Blockers; Humans; Hypertension; Nicardipine; Nifedipine; Nitroprusside; Pra | 1984 |
[Antihypertensives and the prevention of development of genetic hypertension in the hypertensive SHR rat].
Topics: Animals; Antihypertensive Agents; Atenolol; Captopril; Cardiomegaly; Dihydralazine; Dose-Response Re | 1980 |
Haemodynamic effects of nicardipine hydrochloride. Studies during its use to control acute hypertension in anaesthetized patients.
Topics: Acute Disease; Adolescent; Adult; Aged; Anesthesia, General; Female; Hemodynamics; Humans; Hypertens | 1984 |
Effect of nicardipine in a hypertensive patient with diabetes mellitus.
Topics: Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 1; Humans; Hypertension; Male; Mid | 1984 |
Calcium influx mediated vasoconstriction: studies in patients with mild and moderate essential hypertension.
Topics: Adult; Blood Pressure; Calcium; Calcium Channel Blockers; Forearm; Humans; Hypertension; Middle Aged | 1983 |
The effect of a new calcium channel blocker nicardipine on 24-hour ambulatory blood pressure and the pressor response to isometric and dynamic exercise.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Female; Heart Rate; Humans; Hypertension; Iso | 1983 |
Baroreflex setting and sensitivity after acute and chronic nicardipine therapy.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Female; Heart Rate; Humans; Hypertension; Male; Mid | 1984 |
[Calcium antagonists in the management of hypertension].
Topics: Aged; Calcium Channel Blockers; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nicardipine; | 1984 |
Antihypertensive and renal effects of nicardipine.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Glomerular Filtration Rate; Headache; Humans; Hyper | 1984 |
Antihypertensive effect of nicardipine hydrochloride in essential hypertension.
Topics: Adult; Aged; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipin | 1982 |
Specific determination of plasma nicardipine hydrochloride levels by gas chromatography-mass spectrometry.
Topics: Animals; Dogs; Gas Chromatography-Mass Spectrometry; Humans; Hypertension; Nicardipine; Nifedipine; | 1981 |
[Effects of intravenous nicardipine hydrochloride (YC 93), a calcium antagonist, on renal function (author's transl)].
Topics: Glomerular Filtration Rate; Humans; Hypertension; Injections, Intravenous; Kidney; Nicardipine; Nife | 1981 |
Nicardipine: perioperative applications in children.
Topics: Adolescent; Antihypertensive Agents; Blood Pressure; Burns; Calcium Channel Blockers; Child; Child, | 1995 |
Effect of the new calcium antagonist (+/-)-(R*)-3-[(R*)-1-benzyl-3- piperidyl] methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5- pyridinedicarboxylate hydrochloride (KW-3049) on cardiac hypertrophy in spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiomegal | 1993 |
Nicardipine may impair glucose metabolism in hypertensive diabetic patients.
Topics: Adult; Aged; Atenolol; Carteolol; Diabetes Mellitus, Type 2; Diltiazem; Enalapril; Female; Glucose; | 1994 |
Nicardipine, verapamil and response to intubation.
Topics: Antihypertensive Agents; Humans; Hypertension; Intubation, Intratracheal; Nicardipine; Verapamil | 1995 |
Effect of intravenous calcium antagonists on left ventricular diastolic function in hypertension: assessed by pulsed-Doppler echocardiogram.
Topics: Calcium Channel Blockers; Diastole; Diltiazem; Echocardiography, Doppler, Pulsed; Hemodynamics; Huma | 1995 |
M1 receptors in blood pressure-controlled ischemic spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Cerebrovascular Circulation; Cerebrovascular Disorders; Frontal Lobe; Hippo | 1995 |
Proximal and distal pulse pressure after acute antihypertensive vasodilating drugs in Wistar-Kyoto and spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Heart Rate; Hydralazine; H | 1995 |
Antihypertensive effects of AJ-2615, a new calcium antagonist with alpha 1-adrenergic blocking activity in experimental hypertensive animals.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Bloc | 1993 |
Endothelin modulates dihydropyridine receptor decreased binding in hippocampal slices from normotensive and spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1993 |
[Antihypertensive therapy using nicardipine hydrochloride in the treatment of aortic aneurysm].
Topics: Adult; Aged; Aortic Aneurysm, Thoracic; Aortic Dissection; Female; Heart Rate; Humans; Hypertension; | 1995 |
Evaluation of the long-lasting antihypertensive action of 7-O-ethylfangchinoline.
Topics: Alkaloids; Animals; Antihypertensive Agents; Benzylisoquinolines; Blood Pressure; Clonidine; Desoxyc | 1994 |
Control of systemic hypertension with diltiazem, a calcium-antagonist, in patients with a mildly elevated intracranial pressure: a comparative study.
Topics: Aged; Craniotomy; Diltiazem; Humans; Hypertension; Intracranial Pressure; Middle Aged; Nicardipine; | 1994 |
Protective effect of nicardipine treatment on renal microanatomical changes in spontaneously hypertensive rats.
Topics: Albuminuria; Animals; Hypertension; Hypertrophy; Kidney; Kidney Glomerulus; Male; Microscopy, Electr | 1994 |
Diaspirin crosslinked hemoglobin (DCLHb): control of pressor effect with anti-hypertensive agents.
Topics: Animals; Antihypertensive Agents; Aspirin; Blood Pressure; Blood Substitutes; Hemoglobins; Hypertens | 1994 |
Effects of dihydropyridine Ca blockers on the renal function in nephrotic spontaneously hypertensive rat (SHR).
Topics: Animals; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Glome | 1994 |
Effects of long-term treatment with sustained-release nicardipine on left ventricular hypertrophy and function in patients with essential hypertension.
Topics: Aged; Delayed-Action Preparations; Humans; Hypertension; Hypertrophy, Left Ventricular; Middle Aged; | 1994 |
Protective effect of the calcium antagonist NKY-722 against renal and arterial injuries in Dahl salt-sensitive rats.
Topics: Animals; Aorta, Thoracic; Arteries; Blood Pressure; Calcium Channel Blockers; Cerebral Arteries; Dih | 1994 |
Quantitative image analysis study of the cerebral vasodilatory activity of nicardipine in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Cerebral Arteries; Cerebrovascular Circulation; Circle of Willis; Hypertens | 1994 |
Nicardipine for the treatment of hypertension following cardiac transplantation in a 14-year-old boy.
Topics: Adolescent; Heart Transplantation; Humans; Hypertension; Male; Nicardipine; Postoperative Complicati | 1994 |
A new device for indirect blood pressure measurement in rabbits.
Topics: Animals; Blood Pressure Determination; Ear, External; Hypertension; Male; Nicardipine; Rabbits | 1994 |
Modifications in peripheral hemodynamics and left ventricular function in hypertensives treated with nicardipine slow release.
Topics: Adult; Delayed-Action Preparations; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nicardipi | 1994 |
Short-term effects of angiotensin II blockade on renal blood flow and sympathetic activity in awake rats.
Topics: Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Heart | 1994 |
Changes induced by nicardipine slow release in forearm and myocardial hemodynamics of subjects with essential hypertension.
Topics: Adult; Delayed-Action Preparations; Forearm; Hemodynamics; Humans; Hypertension; Male; Middle Aged; | 1994 |
Pharmacological studies on a new dihydrothienopyridine calcium antagonist. 4th communication: prophylactic and therapeutic effects of S-(+)-methyl-4,7-dihydro-3-isobutyl-6-methyl-4-(3-nitrophenyl)thieno[2, 3- b]pyridine-5-carboxylate in stroke-prone spont
Topics: Animals; Behavior, Animal; Blood Pressure; Body Weight; Brain; Calcium Channel Blockers; Cerebrovasc | 1993 |
Effects of dihydropyridines on cerebral blood vessels.
Topics: Administration, Oral; Blood Pressure; Cerebral Infarction; Cerebrovascular Circulation; Cerebrovascu | 1993 |
Intravenous nicardipine in hypertensive children.
Topics: Blood Pressure; Child; Child, Preschool; Drug Evaluation; Female; Humans; Hypertension; Infant; Infa | 1993 |
[The effect of nicardipine on internal carotid artery blood flow velocity, local cerebral blood flow and carbon dioxide reactivity].
Topics: Adult; Aged; Blood Flow Velocity; Carbon Dioxide; Carotid Artery, Internal; Cerebrovascular Circulat | 1993 |
Effect of nicardipine on the blood flow velocity in the vessel near a cerebral aneurysm of the internal carotid artery during cerebral aneurysm surgery: its therapeutic use for intra-operative hypertension.
Topics: Blood Flow Velocity; Brain; Carotid Artery Diseases; Carotid Artery, Internal; Humans; Hypertension; | 1993 |
Pulse pressure gradient along the aortic tree in normotensive Wistar-Kyoto and spontaneously hypertensive rats: effect of nicardipine.
Topics: Animals; Aorta; Blood Pressure; Hypertension; Male; Nicardipine; Pulse; Rats; Rats, Inbred SHR; Rats | 1993 |
[Application of the concept of fuzzy logistic controller for treatment of hypertension during anesthesia].
Topics: Anesthesia; Female; Fuzzy Logic; Humans; Hypertension; Infusion Pumps; Male; Middle Aged; Nicardipin | 1993 |
[Clinical study of total intravenous anesthesia with droperidol, fentanyl and ketamine--effects of nicardipine, diltiazem and nifedipine on intraoperative hypertension].
Topics: Anesthesia, Intravenous; Calcium Channel Blockers; Diltiazem; Droperidol; Female; Fentanyl; Humans; | 1993 |
The acute effect of nicardipine on the renin-angiotensin-aldosterone system in salt-sensitive essential hypertension.
Topics: Adult; Blood Pressure; Female; Furosemide; Heart Rate; Humans; Hypertension; Male; Middle Aged; Natr | 1993 |
Effect of nicardipine treatment on carbohydrate and lipoprotein metabolism in patients with hypertension.
Topics: Adult; Blood Glucose; Carbohydrate Metabolism; Fasting; Female; Glucose; Glucose Tolerance Test; Hum | 1993 |
[Nationwide drug surveillance project on slow-release nicardipine in the short-term therapy of light/moderate arterial hypertension].
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Calcium Channel Blockers; Delayed-Action Pr | 1995 |
Comparison of early and late start of antihypertensive agents and baroreceptor reflexes.
Topics: Aging; Animals; Antihypertensive Agents; Atenolol; Baroreflex; Blood Pressure; Enalapril; Heart Rate | 1996 |
[Anesthesia for cesarean section in a patient with intracranial A-V malformation].
Topics: Adult; Anesthesia, Epidural; Anesthesia, General; Anesthesia, Obstetrical; Cerebral Hemorrhage; Cesa | 1995 |
Renoprotective effect of enalapril in uninephrectomized spontaneously hypertensive rats with neonatal streptozotocin-induced diabetes.
Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Antihyper | 1995 |
Accidental nicardipine overdosage without serious maternal or neonatal consequence.
Topics: Adult; Calcium Channel Blockers; Drug Overdose; Female; Heart Rate, Fetal; Humans; Hypertension; Inf | 1996 |
[Effect of cilnidipine on renal function in SHR and endothelin-induced renal dysfunction].
Topics: Acute Kidney Injury; Animals; Calcium Channel Blockers; Dihydropyridines; Diuresis; Endothelins; Hyp | 1996 |
Hypertensive crisis in children.
Topics: Antihypertensive Agents; Emergencies; Enalapril; Humans; Hypertension; Isradipine; Labetalol; Nicard | 1996 |
Nicardipine to control mean arterial pressure during extracorporeal membrane oxygenation.
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Extracorporeal Membrane Oxygenati | 1996 |
Effects of efonidipine, nicardipine and captopril on proteinuria in aged spontaneously hypertensive rats.
Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Calcium Channel Blockers; | 1996 |
Nicardipine as antihypertensive therapy in liver transplant recipients: results of long-term use.
Topics: Antihypertensive Agents; Cyclosporine; Drug Costs; Female; Humans; Hypertension; Immunosuppressive A | 1997 |
Influence of long-term treatment with the dihydropyridine-type calcium antagonist nicardipine on renal microanatomical changes in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Hypertension; Image Processing, Computer-Assisted | 1995 |
Intravenous nicardipine in the treatment of postoperative arterial hypertension.
Topics: Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Calcium Channel Blockers; Female; Humans; Hyper | 1997 |
Vascular and neuronal hypertensive brain damage: protective effect of treatment with nicardipine.
Topics: Animals; Arteries; Astrocytes; Brain Damage, Chronic; Calcium Channel Blockers; Glial Fibrillary Aci | 1996 |
[Antihypertensive effects of a novel calcium antagonist, AE0047, in various hypertensive models].
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; De | 1997 |
Acute antihypertensive effects of calcium channel blockers are not affected by calcium supplementation in patients with essential hypertension.
Topics: Administration, Oral; Adult; Antihypertensive Agents; Blood Pressure; Calcium; Calcium Channel Block | 1998 |
Nicardipine normalizes elevated levels of antioxidant activity in response to xanthine oxidase-induced oxidative stress in hypertensive rat heart.
Topics: Animals; Antioxidants; Blood Pressure; Blotting, Northern; Calcium Channel Blockers; Glutamate-Cyste | 1998 |
Effects of nicardipine on ventriculo-arterial coupling in humans.
Topics: Adult; Anesthetics, Inhalation; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, | 1998 |
Changes of plasma L-arginine levels in spontaneously hypertensive rats under induced hypotension.
Topics: Animals; Antihypertensive Agents; Arginine; Calcium Channel Blockers; Hypertension; Hypotension; Mal | 1999 |
Therapeutic effects of a calcium antagonist, lacidipine, on stroke-prone spontaneously hypertensive rats with cerebrovascular lesions.
Topics: Animals; Blood Pressure; Body Weight; Brain; Calcium Channel Blockers; Cerebellum; Cerebrovascular D | 1999 |
[A new cause of resistant arterial hypertension: coprescription with anticonvulsant treatments].
Topics: Anticonvulsants; Antihypertensive Agents; Calcium Channel Blockers; Carbamazepine; Drug Interactions | 1999 |
[Effects of nitrendipine on the development of hypertension and renal failure in Dahl salt-sensitive rats].
Topics: Animals; Antihypertensive Agents; Calcium Channel Blockers; Glomerular Filtration Rate; Hypertension | 1999 |
The effects of acute and chronic dihydropyridine calcium antagonist therapy on baroreflex sensitivity: a re-analysis using the sequence method.
Topics: Adult; Baroreflex; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; | 2000 |
Initial experience with isradipine for the treatment of hypertension in children.
Topics: Administration, Oral; Antihypertensive Agents; Blood Pressure; Body Weight; Calcium Channel Blockers | 2000 |
Altered beta-adrenoceptor-mediated responses in the gastric smooth muscle of hypertensive rats.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Calcium Channel Blockers; Colforsin; Electrophysiology; | 2000 |
[Hypertension emergencies].
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Critical Care; Emergencies; Human | 2000 |
Influence of age on L-type Ca2+ channels in the pulmonary artery and vein of spontaneously hypertensive rats.
Topics: Aging; Animals; Autoradiography; Calcium Channel Blockers; Calcium Channels, L-Type; Hypertension; K | 2000 |
Effects of long-term treatment with calcium antagonists on periarterial nerve function in the mesenteric artery of spontaneously hypertensive rats.
Topics: Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Drug Interactions; | 2000 |
The use of short-acting nifedipine in children with hypertension: another example of the need for comprehensive drug testing in children.
Topics: Age Factors; Antihypertensive Agents; Child; Clinical Trials as Topic; Humans; Hypertension; Nicardi | 2001 |
Intravenous nicardipine for treatment of severe hypertension in children.
Topics: Antihypertensive Agents; Blood Pressure; Child; Child, Preschool; Dose-Response Relationship, Drug; | 2001 |
Role of dihydropyridine-sensitive calcium channels in the regulation of norepinephrine release in hypertension.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Dose-Response Relationship, D | 2001 |
Increased activity of calcium channels and Rho-associated kinase in the basilar artery during chronic hypertension in vivo.
Topics: Acetylcholine; Amides; Animals; Antihypertensive Agents; Basilar Artery; Calcium Channel Blockers; C | 2002 |
Antihypertensive effects of MPC-1304, a novel calcium antagonist, in experimental hypertensive rats and dogs.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Co | 1992 |
Effect of nicardipine treatment upon cardiac hypertrophy in spontaneously hypertensive rats: a morphometric and ultrastructural study.
Topics: Animals; Cardiomegaly; Drug Evaluation, Preclinical; Hydralazine; Hypertension; Male; Microscopy, El | 1992 |
Case report: nifedipine-rifampicin interaction attenuates the effect on blood pressure in a patient with essential hypertension.
Topics: Adrenergic alpha-Antagonists; Aged; Blood Pressure; Drug Interactions; Ethambutol; Female; Humans; H | 1992 |
Calcium entry blockade and agonist-mediated vasoconstriction in hypertensive patients.
Topics: Adrenergic alpha-Agonists; Humans; Hypertension; Nicardipine; Vasoconstrictor Agents; Verapamil | 1990 |
Parotitis due to nicardipine.
Topics: Humans; Hypertension; Male; Middle Aged; Nicardipine; Parotitis | 1992 |
Evaluation of lipid metabolism during antihypertensive treatment with nicardipine sr.
Topics: Adult; Aged; Blood Pressure; Cholesterol; Delayed-Action Preparations; Fatty Acids, Nonesterified; F | 1992 |
[Influence of nicardipine on the renin-angiotensin system ina hypertensive crisis during operation in elderly patients].
Topics: Aged; Aged, 80 and over; Female; Humans; Hypertension; Intraoperative Complications; Male; Nicardipi | 1992 |
Changes in the haemodynamics of large arteries induced by single doses of nicardipine, enalapril, atenolol and urapidil.
Topics: Adult; Antihypertensive Agents; Atenolol; Blood Pressure; Brachial Artery; Carotid Arteries; Enalapr | 1992 |
Giant negative U waves in a patient with uncontrolled hypertension and severe hypokalemia.
Topics: Aged; Chronic Disease; Combined Modality Therapy; Drug Therapy, Combination; Electrocardiography; Fe | 1992 |
Effects of nicardipine on the circulatory responses to tracheal intubation in normotensive and hypertensive patients.
Topics: Adult; Aged; Blood Pressure; Drug Evaluation; Female; Heart Rate; Humans; Hypertension; Intubation, | 1992 |
Sublingual nicardipine versus nifedipine to treat hypertensive urgencies.
Topics: Administration, Sublingual; Adult; Blood Pressure; Emergencies; Female; Heart Rate; Humans; Hyperten | 1992 |
The effect of acute and chronic antihypertensive therapy on maternal and fetoplacental Doppler velocimetry.
Topics: Blood Pressure; Brachial Artery; Female; Fetus; Humans; Hypertension; Infant, Newborn; Nicardipine; | 1992 |
Effect of nicardipine on haemodynamic response to stress in hypertension.
Topics: Adult; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nicardipine; Stress, Physiolog | 1992 |
[Control of blood pressure by a calcium antagonist during cataract surgery].
Topics: Aged; Aged, 80 and over; Blood Pressure; Cataract; Cataract Extraction; Female; Humans; Hypertension | 1992 |
[The structural aspects of the pharmacological activity of calcium antagonists. A general profile and the results of a pilot study of nicardipine].
Topics: Delayed-Action Preparations; Drug Evaluation; Female; Hemodynamics; Humans; Hypertension; Male; Midd | 1992 |
The pressor effect of sodium-volume expansion is calcium mediated.
Topics: Animals; Blood Pressure; Blood Volume; Calcium; Calcium Channels; Calcium Chloride; Dogs; Female; Hy | 1991 |
Central hypotensive effects of nicardipine in conscious freely moving spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Hypertension; Injections, Intravenous; Injections, Intraventricular; Male; | 1991 |
[The characteristics of the lung microcirculation and external respiratory function in bronchial asthma patients with systemic arterial hypertension].
Topics: Adult; Asthma; Fenoterol; Humans; Hypertension; Lung; Microcirculation; Middle Aged; Nicardipine; Re | 1991 |
Comparison of the effects of nicardipine and metoprolol on lipid and glycidic metabolism in hypertensive subjects.
Topics: Aged; Blood Glucose; Female; Glucose; Humans; Hypertension; Insulin; Lipid Metabolism; Male; Metopro | 1991 |
[Prevention of hypertension at intubation with intravenous nicardipine].
Topics: Adult; Humans; Hypertension; Infusions, Intravenous; Intubation, Intratracheal; Nicardipine | 1991 |
[Left ventricular function in arterial hypertension in relation to age. The short-term effects of nicardipine].
Topics: Adult; Aged; Aging; Drug Evaluation; Gated Blood-Pool Imaging; Humans; Hypertension; Male; Middle Ag | 1991 |
[Nicardipine inhibits phosphate reabsorption regardless of glomerular filtration rate in hypertensive surgical patients].
Topics: Diuretics; Female; Furosemide; Glomerular Filtration Rate; Humans; Hypertension; Kidney Tubules, Pro | 1991 |
Clinical significance of ambulatory blood pressure monitoring. Evaluation of severity of hypertension, efficacy of treatment and effects on nighttime blood pressure.
Topics: Blood Pressure Determination; Blood Pressure Monitors; Circadian Rhythm; Delayed-Action Preparations | 1991 |
Dizziness in the elderly and calcium channel antagonists.
Topics: Aged; Aged, 80 and over; Calcium Channel Blockers; Diuretics; Dizziness; Drug Therapy, Combination; | 1991 |
Heterogeneous interference of nicardipine, verapamil, and diltiazem with forearm arteriolar responsiveness to adrenergic stimulation in hypertensive patients.
Topics: Arterioles; Diltiazem; Female; Forearm; Humans; Hypertension; Lower Body Negative Pressure; Male; Ni | 1991 |
Effect of the calcium antagonist nicardipine hydrochloride on glucose tolerance and insulin secretion.
Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Blood Pressure; Female; Humans; Hypertension; Insulin | 1991 |
[A case presenting a severe paralytic ileus during the continuous intravenous injection of nicardipine hydrochloride].
Topics: Cerebral Hemorrhage; Humans; Hypertension; Infusions, Intravenous; Intestinal Pseudo-Obstruction; Ma | 1991 |
Antihypertensive and diuretic effects of YM-09730-5, a new calcium antagonist, in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cerebrovascular Disorder | 1991 |
Calcium entry blockade and agonist-mediated forearm vasoconstriction in hypertensive patients. Difference between nicardipine and verapamil.
Topics: Angiotensin II; Forearm; Humans; Hypertension; Lower Body Negative Pressure; Nicardipine; Phentolami | 1991 |
[Clinical study on total intravenous anesthesia with droperidol, fentanyl and ketamine--4. Control of intraoperative hypertension with nicardipine].
Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Droperidol; Female; Fentanyl; Humans; Hypertension | 1991 |
[Effects of nicardipine on hemodynamic variables and on left ventricular function in hypertensive subjects].
Topics: Adult; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nicardipine; Ultrasonography; | 1990 |
[Pre- and postoperative antihypertensive treatment with calcium antagonist in pheochromocytoma].
Topics: Adrenal Gland Neoplasms; Adult; Calcium Channel Blockers; Female; Hemodynamics; Humans; Hypertension | 1990 |
[Comparison of pro-edematous effects of 2 calcium antagonists in bilaterally nephrectomized rats].
Topics: Albumins; Animals; Diltiazem; Edema; Extracellular Space; Hematocrit; Hemodynamics; Hypertension; Ma | 1990 |
[Effects of nicardipine in hypertensive patients with chronic kidney insufficiency].
Topics: Adult; Aged; Drug Evaluation; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Ag | 1990 |
Chronobiologic evaluation of the efficacy of a new calcium antagonist, nicardipine hydrochloride, in 'essential hypertension'.
Topics: Adult; Aged; Blood Pressure; Chronobiology Phenomena; Circadian Rhythm; Drug Administration Schedule | 1990 |
Intravenous nicardipine: an effective new agent for the treatment of severe hypertension.
Topics: Acute Disease; Blood Pressure; Diastole; Drug Evaluation; Female; Humans; Hypertension; Infusions, I | 1990 |
[Effects of i.v. nicardipine in the treatment of hypertensive crisis].
Topics: Acute Disease; Adult; Aged; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nicardipi | 1990 |
Nicardipine in severe hypertension: oral therapy following intravenous treatment.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Infusio | 1990 |
[Results of a study of nicardipine (YC 93) in arterial hypertension in cardiology practice].
Topics: Aged; Blood Pressure; Drug Evaluation; Female; Humans; Hypertension; Middle Aged; Nicardipine | 1990 |
Nicardipine in combination with other antihypertensive drugs: calcium antagonist and prazosin have no additive antihypertensive effect?
Topics: Adult; Aged; Calcium Channel Blockers; Drug Interactions; Drug Therapy, Combination; Female; Humans; | 1990 |
Renal effects of nicardipine, a calcium antagonist, in hypertensive type 2 (non-insulin-dependent) diabetic patients with and without nephropathy.
Topics: Albuminuria; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glomerular Filtration Rate; | 1990 |
Dopaminergic modulation of acute renal effects of nicardipine.
Topics: Blood Pressure; Dopamine; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Male; Metoclopra | 1990 |
Cytosolic free calcium of aorta in hypertensive rats. Chronic inhibition of angiotensin converting enzyme.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Calcium; Cytosol; Hypertension; Male; Musc | 1990 |
[The effect of nicardipine on left ventricular diastolic function in hypertension estimated with pulsed Doppler echocardiography].
Topics: Adult; Aged; Diastole; Double-Blind Method; Echocardiography, Doppler; Female; Heart Ventricles; Hum | 1990 |
Predictive factors of the blood pressure fall induced by intravenous nicardipine.
Topics: Adult; Age Factors; Aged; Blood Pressure; Dose-Response Relationship, Drug; Hemodynamics; Humans; Hy | 1989 |
Verapamil versus nicardipine in rest and exercise hypertension.
Topics: Blood Pressure; Exercise; Heart Rate; Humans; Hypertension; Nicardipine; Verapamil | 1989 |
Effects of long-term nicardipine treatment on hemodynamics of large arteries in essential hypertension.
Topics: Adult; Arteries; Blood Pressure; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middl | 1989 |
[Calcium intestinal absorption in normotensive and essential hypertensive subjects before and after nicardipine].
Topics: Aged; Calcium; Female; Humans; Hypertension; Intestinal Absorption; Male; Middle Aged; Nicardipine | 1989 |
The efficacy of nicardipine and nitroprusside in preventing poststernotomy hypertension.
Topics: Blood Pressure; Cardiac Output; Coronary Artery Bypass; Coronary Disease; Heart Rate; Humans; Hypert | 1989 |
Effects of calcium antagonists and nitroglycerin on atrial natriuretic peptide in normal subjects and patients with essential hypertension.
Topics: Adult; Aged; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Calcium Channel Blockers; Fe | 1989 |
[Arterial hypertension during the rehabilitation phase of cerebral stroke. Study with nicardipine].
Topics: Aged; Aged, 80 and over; Cerebrovascular Disorders; Female; Humans; Hypertension; Male; Middle Aged; | 1989 |
Changes of plasma renin activity and atrial natriuretic factor during intravenous nicardipine treatment of severe hypertension.
Topics: Atrial Natriuretic Factor; Blood Pressure; Humans; Hypertension; Injections, Intravenous; Iodine Rad | 1989 |
Calcium entry blockade and alpha-adrenergic vascular reactivity in human beings: differences between nicardipine and verapamil.
Topics: Adult; Female; Forearm; Histamine; Humans; Hypertension; Male; Middle Aged; Nicardipine; Norepinephr | 1989 |
[Changes in the platelet-vascular system of hemostasis in patients with ischemic heart disease and hypertension after the treatment].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Blood Coagulation; Calcium Channel Blockers; Cor | 1989 |
[New approach to the development of Ca antagonists].
Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Disease; Humans; Hypertension; Nic | 1989 |
[Calcium antagonists in the treatment of hypertension].
Topics: Calcium Channel Blockers; Diltiazem; Humans; Hypertension; Nicardipine; Nifedipine; Verapamil | 1989 |
Effects of CV-4093, a new dihydropyridine calcium channel blocker, on renal hemodynamics and function in stroke-prone spontaneously hypertensive rats (SHRSP).
Topics: Animals; Body Weight; Calcium Channel Blockers; Cerebrovascular Disorders; Dihydropyridines; Hemodyn | 1989 |
[Use of nicardipine in the treatment of arterial hypertension during sternotomy in aorto-coronary bypass surgery].
Topics: Aged; Coronary Artery Bypass; Humans; Hypertension; Intraoperative Complications; Middle Aged; Nicar | 1989 |
[Comparative study of nifedipine and nicardipine in the treatment of hypertensive crisis after aortocoronary bypass].
Topics: Coronary Artery Bypass; Humans; Hypertension; Nicardipine; Nifedipine; Postoperative Complications | 1989 |
Effect of sodium intake on the hypotensive effect of calcium antagonists.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Blood Pressure; Epinephrine; Female; Heart Rate; Humans; Hypert | 1989 |
Effects of nicardipine on blood pressure and renal function in elderly hypertensive patients with renal dysfunction.
Topics: Aged; Aldosterone; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Cholesterol; Creatinine; Elec | 1989 |
Effect of nicardipine on insulin secretion, glucose and lipid metabolism in hypertensive, non-insulin dependent diabetics.
Topics: Adult; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Female; Heart Rate; Humans; Hyperte | 1989 |
Characteristics of pressor response to endothelin in spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Endothelins; Hypertension | 1989 |
Nicardipine--a new calcium-entry blocker.
Topics: Angina Pectoris; Costs and Cost Analysis; Drug Interactions; Hemodynamics; Humans; Hypertension; Myo | 1989 |
Chronic inhibition of angiotensin converting enzyme decreases Ca2+-dependent tone of aorta in hypertensive rats.
Topics: Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Calc | 1989 |
Calcium entry blockade, autonomic activity and exercise performance in essential hypertensive patients.
Topics: Adult; Autonomic Nervous System; Calcium Channel Blockers; Exercise; Exercise Test; Female; Heart; H | 1989 |
Fetal vascular responses to maternal nicardipine administration in the hypertensive ewe.
Topics: Angiotensin II; Animals; Blood Gas Analysis; Female; Fetal Blood; Fetal Heart; Hypertension; Nicardi | 1989 |
Placental vascular responses to nicardipine in the hypertensive ewe.
Topics: Angiotensin II; Animals; Female; Hypertension; Nicardipine; Placenta; Pregnancy; Pregnancy Complicat | 1989 |
Fatty acid binding protein of cardiac muscle in spontaneously hypertensive rats: effect of hypertrophy and its regression.
Topics: Animals; Blood Pressure; Cardiomegaly; Carrier Proteins; Enalapril; Fatty Acid-Binding Protein 7; Fa | 1988 |
Hypertension in the elderly: focus on nicardipine. Proceedings of a symposium. May 26, 1988, Kyoto, Japan.
Topics: Aged; Humans; Hypertension; Nicardipine | 1989 |
Nicardipine in the elderly hypertensive: a review of experience in the United Kingdom.
Topics: Adult; Aged; Blood Pressure; Humans; Hypertension; Middle Aged; Nicardipine | 1989 |
The clinical performance of nicardipine in elderly hypertensive patients with concomitant diseases.
Topics: Aged; Arterial Occlusive Diseases; Blood Pressure; Coronary Disease; Diabetes Complications; Humans; | 1989 |
Electrophysiologic evaluation of intravenous nicardipine in man.
Topics: Blood Pressure; Bundle of His; Cardiomyopathy, Hypertrophic; Coronary Disease; Electrocardiography; | 1989 |
[Arterial hypertension, myocardial hypertrophy and disorders of cardiac rhythm induced by ligation of the left coronary artery in the rat].
Topics: Animals; Cardiomegaly; Coronary Disease; Coronary Vessels; Hypertension; Ligation; Male; Nicardipine | 1987 |
[Effects of nicardipine in the treatment of essential arterial hypertension].
Topics: Aged; Calcium Channel Blockers; Humans; Hypertension; Middle Aged; Nicardipine | 1988 |
[Effects of medium- and long-term treatment with nicardipine on arterial blood pressure, hemodynamics and renal function in patients with arterial hypertension of mild and moderate degree].
Topics: Adult; Aged; Blood Pressure; Female; Follow-Up Studies; Humans; Hypertension; Kidney; Male; Middle A | 1988 |
[Echocardiographic analysis of anatomical and functional changes in the left heart ventricle during antihypertensive treatment with nicardipine].
Topics: Adult; Blood Pressure; Cardiomegaly; Drug Evaluation; Echocardiography; Female; Heart; Hemodynamics; | 1988 |
[Influence of sodium intake on antihypertensive effect of calcium antagonist].
Topics: Administration, Oral; Aldosterone; Blood Pressure; Catecholamines; Female; Heart Rate; Humans; Hyper | 1988 |
Natriuretic and renal hemodynamic effects of nicardipine in essential hypertension.
Topics: Administration, Oral; Aldosterone; Blood Pressure; Heart Rate; Hemodynamics; Humans; Hypertension; I | 1988 |
Antihypertensive drugs and sodium restriction. Analysis of their interaction based on pressure-natriuresis relationship.
Topics: Antihypertensive Agents; Blood Pressure; Captopril; Diet, Sodium-Restricted; Female; Humans; Hyperte | 1988 |
Antihypertensive effects of the new calcium antagonist benidipine hydrochloride in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chemical Phenomena; Chem | 1988 |
[Acute response to calcium inhibitors in secondary arterial hypertension: does renin play a role?].
Topics: Adult; Aldosterone; Blood Pressure; Heart Rate; Humans; Hyperaldosteronism; Hypertension; Hypertensi | 1988 |
[Treatment of hypertensive attacks in children with nicardipine].
Topics: Acute Disease; Adolescent; Blood Pressure; Child; Child, Preschool; Female; Heart Rate; Humans; Hype | 1988 |
Antihypertensive effects of intravenous administration of benidipine hydrochloride and some other calcium antagonists in conscious, spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diltiazem; Dose-Response | 1988 |
[Evaluation of anatomical and functional changes in the left heart ventricle during the treatment with nicardipine: clinical significance of M-mode echocardiographic indices].
Topics: Echocardiography; Heart; Hemodynamics; Humans; Hypertension; Nicardipine | 1988 |
[Influence of nicardipine on endocrine functions in post-operative patients].
Topics: Aged; Endocrine Glands; Humans; Hypertension; Middle Aged; Nicardipine; Postoperative Complications | 1988 |
Intravenous nicardipine for the treatment of severe hypertension.
Topics: Adult; Aged; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Infusions, Intravenous; Male; | 1988 |
Renal effects of nicardipine in essential hypertension: differences between acute and chronic therapy.
Topics: Adult; Blood Pressure; Diuresis; Drug Administration Schedule; Electrolytes; Female; Glomerular Filt | 1987 |
Effects of calcium entry blockers on blood pressure and heart rate in neurogenic hypertensive dogs.
Topics: Animals; Bepridil; Blood Pressure; Calcium Channel Blockers; Denervation; Diltiazem; Dogs; Female; H | 1987 |
Effects of intravenous administration of a calcium antagonist on prostaglandins and thromboxane in plasma and urine in humans.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aldosterone; Blood Pressure; Calcium Channel Blockers; Dinopros | 1986 |
Influence of baseline hemodynamic status and sympathetic activity on the response to nicardipine, a new dihydropyridine, in patients with hypertension or chronic congestive heart failure.
Topics: Adult; Aged; Female; Heart Failure; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nicardipi | 1987 |
Comparative antihypertensive effects of nifedipine and nicardipine in adult and aged spontaneously hypertensive rats.
Topics: Aging; Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Hypertension; Nicardipine; Nife | 1987 |
[Nicardipine in the treatment of arterial hypertension: echocardiographic evaluation].
Topics: Adult; Echocardiography; Female; Heart; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nicar | 1987 |
Systemic and pulmonary hemodynamic responses to nicardipine during graded ergometric exercise in patients with moderate to severe essential hypertension.
Topics: Adult; Aged; Female; Hemodynamics; Hormones; Humans; Hypertension; Male; Middle Aged; Nicardipine; P | 1987 |
Effects of nicardipine on the systemic and renal hemodynamics in acutely elevated blood pressure induced by vasoactive agents in conscious rabbits.
Topics: Angiotensin II; Animals; Blood Pressure; Denervation; Drug Evaluation, Preclinical; Female; Heart Ra | 1987 |
[Nicardipine: a calcium antagonist for the treatment of arterial hypertension].
Topics: Aged; Drug Evaluation; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine | 1987 |
Use of nicardipine in the anesthetic management of pheochromocytoma.
Topics: Adult; Anesthesia, Local; Blood Pressure; Cardiac Output; Epinephrine; Female; Fentanyl; Heart Rate; | 1986 |
[Impaired diastolic function and its mechanism in mild hypertension--assessment by exercise echocardiography and calcium antagonist].
Topics: Adult; Calcium Channel Blockers; Diastole; Echocardiography; Exercise Test; Hemodynamics; Humans; Hy | 1986 |
[Influence of long-term antihypertensive treatment on cerebral ischemia induced by bilateral common carotid artery ligation in SHRSR--protective effect of nicardipine hydrochloride].
Topics: Animals; Blood Pressure; Brain; Brain Ischemia; Carotid Arteries; Cerebral Arteries; Hypertension; L | 1987 |
Vasodilatory effect of nicardipine and verapamil in the forearm of hypertensive as compared with normotensive man.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Forearm; Humans; Hypertension; Middle Aged; N | 1985 |
Calcium channel blockers--are they diuretics?
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Diuretics; Female; Humans; Hypertension; Kidney Tub | 1985 |
Cardiovascular, baroreflex and humoral responses in hypertensive patients during nicardipine therapy.
Topics: Adult; Aldosterone; Carotid Arteries; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle A | 1985 |
[Acute and chronic effects of a new calcium blocker, nicardipine, on renal hemodynamics in arterial hypertension].
Topics: Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine; | 1985 |
A study of the long-term efficacy and tolerability of oral nicardipine in hypertensive patients.
Topics: Administration, Oral; Adult; Aged; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Mid | 1985 |
The effect of acute and chronic nicardipine therapy on forearm arterial haemodynamics in essential hypertension.
Topics: Blood Pressure; Calcium; Calcium Channel Blockers; Female; Forearm; Heart Rate; Hemodynamics; Humans | 1985 |
The effect of nicardipine on blood pressure, its variability and reflex cardiac control.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Female; Heart Rate; Humans; Hypertension; Male; Mid | 1985 |
[Treatment of arterial hypertension with a calcium-channel blocking agent, nicardipine hydrochloride].
Topics: Adult; Aged; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine; | 1985 |
[Effect of nicardipine on cholesterol-fed S.H.R].
Topics: Animals; Aorta; Arteriosclerosis; Body Weight; Heart Rate; Hyperlipidemias; Hypertension; Lipids; Li | 1985 |
Nicardipine and nifedipine: effects on diuresis and serum aldosterone levels in spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Blood Pressure; Diuresis; Hypertension; Male; Nicardipine; Nifedipine; Rats; R | 1985 |