nicardipine has been researched along with Hypertension, Renal in 15 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
Hypertension, Renal: Persistent high BLOOD PRESSURE due to KIDNEY DISEASES, such as those involving the renal parenchyma, the renal vasculature, or tumors that secrete RENIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Isradipine is an effective, orally administered agent for control of hypertension in children." | 7.70 | Initial experience with isradipine for the treatment of hypertension in children. ( Groshong, T; Strauser, LM; Tobias, JD, 2000) |
| "Isradipine is an effective, orally administered agent for control of hypertension in children." | 3.70 | Initial experience with isradipine for the treatment of hypertension in children. ( Groshong, T; Strauser, LM; Tobias, JD, 2000) |
| "3-3 mg/kg), dose-response curves of the antihypertensive effect did not change and body weight gain was equal to that of the vehicle-treated group." | 1.28 | Antihypertensive effects of MPC-1304, a novel calcium antagonist, in experimental hypertensive rats and dogs. ( Haruno, A; Kanda, A; Miyake, H; Nagasaka, M, 1992) |
| " Tolerance of the antihypertensive effect of TC-81 in daily dosing for 2 weeks and the rebound phenomena after discontinuance of the treatment were not observed in RHD." | 1.28 | Antihypertensive effect of the new dihydropyridine calcium antagonist (+-)-3-(benzylmethylamino)-2,2-dimethylpropyl methyl 4-(2-fluoro-5-nitrophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedica rbo xylate hydrochloride in dogs. ( Aoki, K; Kishimoto, T; Naruchi, T; Okamiya, Y; Sunakawa, K; Takeshita, T; Tanabe, H, 1992) |
| " In conclusion, nicardipine, alone or in combination with enalapril, is an effective and well tolerated drug for use in treatment of hypertension secondary to chronic renal disease." | 1.28 | [Nicardipine, alone or in combination with enalapril, in the therapy of arterial hypertension secondary to chronic nephropathy]. ( Feriozzi, S; Mavrikakis, G; Morabito, S; Pecci, G; Pierucci, A; Roscia, E; Simonetti, BM, 1989) |
| " Nisoldipine had the lowest maximum plasma concentration and the longest elimination half-life among the four 1,4-dihydropyridines, resulting in no significant difference in the area under the plasma concentration-time curve." | 1.27 | Comparative study on acute antihypertensive effects and pharmacokinetics of nisoldipine, nifedipine, nimodipine and nicardipine administered orally to conscious renal hypertensive dogs. ( Kato, H; Takata, Y, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (20.00) | 18.7374 |
| 1990's | 10 (66.67) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kumagai, H | 2 |
| Suzuki, H | 2 |
| Ichikawa, M | 1 |
| Nishizawa, M | 1 |
| Ryuzaki, M | 2 |
| Kumagai, K | 1 |
| Saruta, T | 2 |
| Hoshino, J | 1 |
| Sakamaki, T | 1 |
| Nakamura, T | 1 |
| Kobayashi, M | 1 |
| Kato, M | 1 |
| Sakamoto, H | 1 |
| Kurashina, T | 1 |
| Yagi, A | 1 |
| Sato, K | 1 |
| Ono, Z | 1 |
| Kido, H | 1 |
| Nishikawa, M | 1 |
| Hayashi, K | 1 |
| Kubo, Y | 1 |
| Ohtaki, Y | 1 |
| Fujino, Y | 1 |
| Egi, Y | 1 |
| Ebisu, H | 1 |
| Inoue, S | 1 |
| Yamanaga, K | 1 |
| Uchida, T | 1 |
| Nakamura, N | 1 |
| Michael, J | 1 |
| Groshong, T | 2 |
| Tobias, JD | 2 |
| Sabbatini, M | 1 |
| Leonardi, A | 1 |
| Testa, R | 1 |
| Vitaioli, L | 1 |
| Amenta, F | 1 |
| Strauser, LM | 1 |
| Kanda, A | 1 |
| Haruno, A | 1 |
| Miyake, H | 1 |
| Nagasaka, M | 1 |
| Matsumura, Y | 1 |
| Melina, D | 1 |
| Guerrera, G | 1 |
| Santoliquido, A | 1 |
| Guerrera, C | 1 |
| Musumeci, V | 1 |
| Nicolò, G | 1 |
| Cataldo, R | 1 |
| Okamiya, Y | 1 |
| Kishimoto, T | 1 |
| Sunakawa, K | 1 |
| Aoki, K | 1 |
| Tanabe, H | 1 |
| Takeshita, T | 1 |
| Naruchi, T | 1 |
| Bianchi, S | 1 |
| Bigazzi, R | 1 |
| Baldari, G | 1 |
| Campese, VM | 1 |
| Oizumi, K | 1 |
| Miyamoto, M | 1 |
| Koike, H | 1 |
| Pecci, G | 1 |
| Feriozzi, S | 1 |
| Morabito, S | 1 |
| Mavrikakis, G | 1 |
| Roscia, E | 1 |
| Simonetti, BM | 1 |
| Pierucci, A | 1 |
| Karasawa, A | 1 |
| Ikeda, J | 1 |
| Yamada, K | 1 |
| Kubo, K | 1 |
| Oka, T | 1 |
| Nakamizo, N | 1 |
| Takata, Y | 1 |
| Kato, H | 1 |
1 trial available for nicardipine and Hypertension, Renal
| Article | Year |
|---|---|
Long-term effects of enalapril and nicardipine on urinary albumin excretion in patients with chronic renal insufficiency: a 1-year follow-up.
Topics: Albuminuria; Enalapril; Female; Follow-Up Studies; Humans; Hypertension, Renal; Kidney Failure, Chro | 1991 |
14 other studies available for nicardipine and Hypertension, Renal
| Article | Year |
|---|---|
Different responses of renal blood flow and sympathetic nerve activity to captopril and nicardipine in conscious renal hypertensive rabbits.
Topics: Analysis of Variance; Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Captopril; Dise | 1995 |
Exaggerated vascular response due to endothelial dysfunction and role of the renin-angiotensin system at early stage of renal hypertension in rats.
Topics: Acetylcholine; Animals; Blood Vessels; Endothelium, Vascular; Hypertension, Renal; Male; Nicardipine | 1994 |
[Antihypertensive effects of a novel calcium antagonist, AE0047, in various hypertensive models].
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; De | 1997 |
Nicardipine for hypertensive emergencies in children with renal disease.
Topics: Adolescent; Calcium Channel Blockers; Child; Emergency Medical Services; Female; Humans; Hypertensio | 1998 |
Effect of calcium antagonists on glomerular arterioles in spontaneously hypertensive rats.
Topics: Albuminuria; Animals; Arterioles; Calcium; Calcium Channel Blockers; Dihydropyridines; Hydralazine; | 2000 |
Initial experience with isradipine for the treatment of hypertension in children.
Topics: Administration, Oral; Antihypertensive Agents; Blood Pressure; Body Weight; Calcium Channel Blockers | 2000 |
Antihypertensive effects of MPC-1304, a novel calcium antagonist, in experimental hypertensive rats and dogs.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Co | 1992 |
Differential effects of captopril and nicardipine on baroreflex control of sympathetic nerve activity and heart rate in renal hypertension.
Topics: Angiotensin II; Animals; Arginine; Blood Pressure; Captopril; Female; Heart Rate; Hypertension, Rena | 1992 |
[Efficacy of the combination of nicardipine-enalapril and atenolol in severe hypertension secondary to chronic renal disease].
Topics: Adult; Atenolol; Chronic Disease; Drug Therapy, Combination; Enalapril; Female; Humans; Hypertension | 1992 |
Antihypertensive effect of the new dihydropyridine calcium antagonist (+-)-3-(benzylmethylamino)-2,2-dimethylpropyl methyl 4-(2-fluoro-5-nitrophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedica rbo xylate hydrochloride in dogs.
Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyrid | 1992 |
Antihypertensive effect of CS-905, a novel dihydropyridine calcium blocker, in conscious hypertensive dogs.
Topics: Animals; Antihypertensive Agents; Azetidinecarboxylic Acid; Azetines; Calcium Channel Blockers; Dihy | 1990 |
[Nicardipine, alone or in combination with enalapril, in the therapy of arterial hypertension secondary to chronic nephropathy].
Topics: Adult; Drug Evaluation; Drug Therapy, Combination; Enalapril; Female; Glomerulonephritis, IGA; Glome | 1989 |
Antihypertensive effects of the new calcium antagonist benidipine hydrochloride in conscious, renal-hypertensive dogs.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chemical Phenomena; Chem | 1988 |
Comparative study on acute antihypertensive effects and pharmacokinetics of nisoldipine, nifedipine, nimodipine and nicardipine administered orally to conscious renal hypertensive dogs.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Dogs; Dose-Response Relation | 1986 |