nicardipine has been researched along with Hypertension, Pulmonary in 8 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pulmonary vascular response to the inhalation of various concentrations of oxygen (FIO2) was studied under basal conditions and after nicardipine in 10 patients with pulmonary hypertension secondary to chronic bronchitis." | 10.17 | [Acute effects of nicardipine on the vascular reactivity of oxygen in patients with respiratory insufficiency and pulmonary hypertension]. ( Lévy, S; Paganelli, F; Philip-Joët, F; Saadjian, A; Saadjian, M, 1993) |
| "We compared the acute effects of nicardipine and a placebo on the response of pulmonary and systemic circulation to different inspiratory fractional concentrations of O2 (FiO2) in 10 patients with pulmonary hypertension secondary to chronic obstructive lung disease." | 9.07 | Effects of nicardipine on pulmonary and systemic vascular reactivity to oxygen in patients with pulmonary hypertension secondary to chronic obstructive lung disease. ( Arnaud, A; Durand, A; Hot, B; Levy, S; Philip-Joët, F; Reynaud-Gaubert, M; Saadjian, A, 1991) |
| "Pulmonary vascular response to the inhalation of various concentrations of oxygen (FIO2) was studied under basal conditions and after nicardipine in 10 patients with pulmonary hypertension secondary to chronic bronchitis." | 6.17 | [Acute effects of nicardipine on the vascular reactivity of oxygen in patients with respiratory insufficiency and pulmonary hypertension]. ( Lévy, S; Paganelli, F; Philip-Joët, F; Saadjian, A; Saadjian, M, 1993) |
| "We compared the acute effects of nicardipine and a placebo on the response of pulmonary and systemic circulation to different inspiratory fractional concentrations of O2 (FiO2) in 10 patients with pulmonary hypertension secondary to chronic obstructive lung disease." | 5.07 | Effects of nicardipine on pulmonary and systemic vascular reactivity to oxygen in patients with pulmonary hypertension secondary to chronic obstructive lung disease. ( Arnaud, A; Durand, A; Hot, B; Levy, S; Philip-Joët, F; Reynaud-Gaubert, M; Saadjian, A, 1991) |
| "The potent vasodilators nicardipine and prostaglandin E1 (PGE1) are useful for the treatment of systemic hypertension or pulmonary hypertension during aortic surgery." | 3.74 | The comparative effects of intravenous nicardipine and prostaglandin E1 on the cerebral pial arteriolar constriction seen after unclamping of an aortic cross-clamp in rabbits. ( Dohi, S; Iida, H; Iida, M; Kumazawa, M; Takenaka, M; Uchida, M, 2007) |
| "Nicardipine was administered by short-time continuous infusion (1 μg·kg⁻¹·min⁻¹ for 5 min and 2 μg·kg⁻¹·min⁻¹ for 5 min) followed by bolus injection (5 μg/kg)." | 1.38 | Acute vasoreactivity testing with nicardipine in patients with pulmonary arterial hypertension. ( Akagi, S; Fujio, H; Fuke, S; Ito, H; Kiyooka, T; Kohno, K; Kusano, KF; Matsubara, H; Miyaji, K; Mizoguchi, H; Morita, H; Nagase, S; Nakamura, K; Ogawa, A; Ohe, T; Saito, Y, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamamura, A | 1 |
| Aoshima, D | 1 |
| Murata, T | 1 |
| Hori, M | 1 |
| Ozaki, H | 1 |
| Saito, Y | 1 |
| Nakamura, K | 1 |
| Miyaji, K | 1 |
| Akagi, S | 1 |
| Mizoguchi, H | 1 |
| Ogawa, A | 1 |
| Fuke, S | 1 |
| Fujio, H | 1 |
| Kiyooka, T | 1 |
| Nagase, S | 1 |
| Kohno, K | 1 |
| Morita, H | 1 |
| Kusano, KF | 1 |
| Matsubara, H | 1 |
| Ohe, T | 1 |
| Ito, H | 1 |
| Kumazawa, M | 1 |
| Iida, H | 1 |
| Uchida, M | 1 |
| Iida, M | 1 |
| Takenaka, M | 1 |
| Dohi, S | 1 |
| Saadjian, A | 2 |
| Philip-Joët, F | 2 |
| Paganelli, F | 1 |
| Saadjian, M | 1 |
| Lévy, S | 2 |
| Uren, NG | 1 |
| Ludman, PF | 1 |
| Crake, T | 1 |
| Oakley, CM | 1 |
| Hot, B | 1 |
| Reynaud-Gaubert, M | 1 |
| Durand, A | 1 |
| Arnaud, A | 1 |
| Tamburino, C | 1 |
| Russo, G | 1 |
| Di Paola, R | 1 |
| Passaniti, A | 1 |
| Zisa, MB | 1 |
| Felis, S | 1 |
| Calvi, V | 1 |
| Alì, A | 1 |
| Cinnirella, C | 1 |
| Giuffrida, G | 1 |
2 reviews available for nicardipine and Hypertension, Pulmonary
| Article | Year |
|---|---|
Molecular Mechanism of Dihydropyridine Ca
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Dihydropyridines; Disease Models, Ani | 2016 |
[Acute effects of nicardipine on the vascular reactivity of oxygen in patients with respiratory insufficiency and pulmonary hypertension].
Topics: Blood Gas Analysis; Clinical Protocols; Hemodynamics; Humans; Hypertension, Pulmonary; Male; Nicardi | 1993 |
2 trials available for nicardipine and Hypertension, Pulmonary
| Article | Year |
|---|---|
[Acute effects of nicardipine on the vascular reactivity of oxygen in patients with respiratory insufficiency and pulmonary hypertension].
Topics: Blood Gas Analysis; Clinical Protocols; Hemodynamics; Humans; Hypertension, Pulmonary; Male; Nicardi | 1993 |
Effects of nicardipine on pulmonary and systemic vascular reactivity to oxygen in patients with pulmonary hypertension secondary to chronic obstructive lung disease.
Topics: Blood Gas Analysis; Cardiac Output; Hemodynamics; Humans; Hypertension, Pulmonary; Lung Diseases, Ob | 1991 |
5 other studies available for nicardipine and Hypertension, Pulmonary
| Article | Year |
|---|---|
Time-dependent phenotypic and contractile changes of pulmonary artery in chronic hypoxia-induced pulmonary hypertension.
Topics: Actins; Amides; Animals; Cell Proliferation; Endothelin-1; Hypertension, Pulmonary; Hypoxia; Immunoh | 2009 |
Acute vasoreactivity testing with nicardipine in patients with pulmonary arterial hypertension.
Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Cardiac Output; Dose-Response Relationship | 2012 |
The comparative effects of intravenous nicardipine and prostaglandin E1 on the cerebral pial arteriolar constriction seen after unclamping of an aortic cross-clamp in rabbits.
Topics: Alprostadil; Animals; Aorta; Arteries; Blood Pressure; Cerebrovascular Circulation; Hypertension; Hy | 2007 |
Response of the pulmonary circulation to acetylcholine, calcitonin gene-related peptide, substance P and oral nicardipine in patients with primary pulmonary hypertension.
Topics: Acetylcholine; Adult; Calcitonin Gene-Related Peptide; Endothelium, Vascular; Female; Humans; Hypert | 1992 |
[Bolus nicardipine in the hemodynamic assessment for heart transplantation of patients with severe failure of ischemic origin and high pulmonary resistance].
Topics: Adult; Cardiac Catheterization; Coronary Angiography; Coronary Disease; Female; Heart Failure; Heart | 1991 |