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nicardipine and Hypertension, Portal

nicardipine has been researched along with Hypertension, Portal in 4 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Hypertension, Portal: Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN.

Research Excerpts

ExcerptRelevanceReference
"Portal hypertension was induced in rats by partial portal vein ligation."1.29Effects of calcium antagonists on hepatic and systemic hemodynamics in awake portal hypertensive rats. ( Kawasaki, T; Nagasawa, M; Yoshimi, T, 1996)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
García-Pagán, JC1
Feu, F1
Luca, A1
Fernández, M1
Pizcueta, P1
Bosch, J1
Rodés, J1
Iwao, T2
Toyonaga, A2
Ikegami, M2
Oho, K2
Sumino, M2
Sakaki, M2
Shigemori, H1
Nakayama, M1
Sasaki, E1
Tanikawa, K1
Nagasawa, M1
Kawasaki, T1
Yoshimi, T1
Sugawara, H1
Takagi, K1
Ohkubo, K1
Inoue, R1

Trials

2 trials available for nicardipine and Hypertension, Portal

ArticleYear
Nicardipine increases hepatic blood flow and the hepatic clearance of indocyanine green in patients with cirrhosis.
    Journal of hepatology, 1994, Volume: 20, Issue:6

    Topics: Aged; Female; Hemodynamics; Humans; Hypertension, Portal; Indocyanine Green; Liver Circulation; Live

1994
Effects of vasopressin and nicardipine on hemodynamics and liver function in patients with cirrhosis: comparison with vasopressin alone.
    Journal of hepatology, 1993, Volume: 19, Issue:3

    Topics: Aged; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension, Portal; Liver; Liver Ci

1993

Other Studies

2 other studies available for nicardipine and Hypertension, Portal

ArticleYear
Effects of calcium antagonists on hepatic and systemic hemodynamics in awake portal hypertensive rats.
    Journal of gastroenterology, 1996, Volume: 31, Issue:3

    Topics: Animals; Calcium Channel Blockers; Consciousness; Diltiazem; Hemodynamics; Hypertension, Portal; Liv

1996
Nicardipine infusion improved hepatic function but failed to reduce hepatic venous pressure gradient in patients with cirrhosis.
    The American journal of gastroenterology, 1992, Volume: 87, Issue:3

    Topics: Adult; Aged; Female; Hemodynamics; Humans; Hypertension, Portal; Infusions, Intravenous; Liver; Live

1992