Page last updated: 2024-11-01

nicardipine and Goldblatt Syndrome

nicardipine has been researched along with Goldblatt Syndrome in 10 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Research Excerpts

ExcerptRelevanceReference
"Nicardipine treatment allowed blood pressure control, reduction of left ventricular mass, and improvement in mechanical performance, but was unable to restore minimal coronary vascular resistance."5.28Nicardipine and cardiac hypertrophy: effects on left ventricular mass. Haemodynamics and mechanical performance in renovascular hypertensive rats. ( Besse, P; Bonoron-Adèle, S; Grellet, J; Stuyvers, B; Tariosse, L, 1991)
" These results suggested that AJ-2615 has potential as a long-acting (once daily dosage regimen) antihypertensive drug without causing a steep blood pressure fall and tachycardia."1.29Antihypertensive effects of AJ-2615, a new calcium antagonist with alpha 1-adrenergic blocking activity in experimental hypertensive animals. ( Fukuya, F; Hosoki, K; Ikeno, A; Karasawa, T; Minato, H; Nose, I; Takeyama, K, 1993)
"Nicardipine treatment allowed blood pressure control, reduction of left ventricular mass, and improvement in mechanical performance, but was unable to restore minimal coronary vascular resistance."1.28Nicardipine and cardiac hypertrophy: effects on left ventricular mass. Haemodynamics and mechanical performance in renovascular hypertensive rats. ( Besse, P; Bonoron-Adèle, S; Grellet, J; Stuyvers, B; Tariosse, L, 1991)
"Nicardipine treatment (10 to 15 mg intraperitoneal dosage during 8 weeks), led to: an efficient but incomplete control of hypertension."1.27[Effects of nicardipine on left ventricular hypertrophy of the rat with renovascular arterial hypertension]. ( Besse, P; Bonoron-Adèle, S; Grellet, J; Stuyvers, B; Tariosse, L, 1988)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19904 (40.00)18.7374
1990's5 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tsuchida, T1
Yano, H1
Raita, Y1
Kinjo, M1
Ikeno, A1
Nose, I1
Fukuya, F1
Minato, H1
Takeyama, K1
Hosoki, K1
Karasawa, T1
Kato, T1
Noguchi, K1
Sakanashi, M1
Kumagai, H1
Suzuki, H1
Ichikawa, M1
Matsumura, Y1
Jimbo, M1
Ryuzaki, M1
Saruta, T1
Grellet, J2
Bonoron-Adèle, S2
Stuyvers, B2
Tariosse, L2
Besse, P2
Chauveau, D1
Houillier, P1
Azizi, M1
Sassano, P2
Guyenne, TT1
Jeunemaître, X2
Plouin, PF2
Corvol, P2
Yang, Y1
Chen, K1
Chen, DG1
Kessler, M1
Netter, P1
Renoult, E1
Jonon, B1
Mur, JM1
Trechot, P1
Dousset, B1
Valenta de Almeida, L1
Farge, D1
Guyene, TT1
Julien, J1

Reviews

1 review available for nicardipine and Goldblatt Syndrome

ArticleYear
[Use of intravenous nicardipine for the diagnosis of renovascular hypertension].
    Archives des maladies du coeur et des vaisseaux, 1991, Volume: 84, Issue:8

    Topics: Adult; Aged; Clinical Protocols; Female; Humans; Hypertension; Hypertension, Renovascular; Injection

1991

Trials

1 trial available for nicardipine and Goldblatt Syndrome

ArticleYear
[Use of intravenous nicardipine for the diagnosis of renovascular hypertension].
    Archives des maladies du coeur et des vaisseaux, 1991, Volume: 84, Issue:8

    Topics: Adult; Aged; Clinical Protocols; Female; Humans; Hypertension; Hypertension, Renovascular; Injection

1991

Other Studies

9 other studies available for nicardipine and Goldblatt Syndrome

ArticleYear
Nephrotic range proteinuria and metabolic alkalosis in Takayasu arteritis.
    BMJ case reports, 2019, Apr-15, Volume: 12, Issue:4

    Topics: Adolescent; Alkalosis; Amlodipine; Antihypertensive Agents; Female; Glomerulosclerosis, Focal Segmen

2019
Antihypertensive effects of AJ-2615, a new calcium antagonist with alpha 1-adrenergic blocking activity in experimental hypertensive animals.
    Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:5

    Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Bloc

1993
Evaluation of the long-lasting antihypertensive action of 7-O-ethylfangchinoline.
    Japanese journal of pharmacology, 1994, Volume: 66, Issue:1

    Topics: Alkaloids; Animals; Antihypertensive Agents; Benzylisoquinolines; Blood Pressure; Clonidine; Desoxyc

1994
Central and peripheral vasopressin interact differently with sympathetic nervous system and renin-angiotensin system in renal hypertensive rabbits.
    Circulation research, 1993, Volume: 72, Issue:6

    Topics: Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Captopril; Clonidine; Disease Models,

1993
Nicardipine and cardiac hypertrophy: effects on left ventricular mass. Haemodynamics and mechanical performance in renovascular hypertensive rats.
    Cardiovascular research, 1991, Volume: 25, Issue:6

    Topics: Animals; Cardiomegaly; Hemodynamics; Hypertension, Renovascular; Male; Myocardial Contraction; Nephr

1991
[Clonidine stimulates central nervous alpha 2 adrenoceptors not mediating Ca2+ channels].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1989, Volume: 10, Issue:6

    Topics: Animals; Blood Pressure; Calcium Channels; Clonidine; Dogs; Female; Heart Rate; Hypertension, Renova

1989
Influence of nicardipine on renal function and plasma cyclosporin in renal transplant patients.
    European journal of clinical pharmacology, 1989, Volume: 36, Issue:6

    Topics: Adult; Animals; Creatinine; Cyclosporins; Drug Interactions; Female; Humans; Hypertension, Renovascu

1989
[Effects of nicardipine on left ventricular hypertrophy of the rat with renovascular arterial hypertension].
    Archives des maladies du coeur et des vaisseaux, 1988, Volume: 81 Spec No

    Topics: Animals; Cardiomegaly; Coronary Circulation; Hemodynamics; Hypertension, Renovascular; Male; Myocard

1988
[Acute response to calcium inhibitors in secondary arterial hypertension: does renin play a role?].
    Archives des maladies du coeur et des vaisseaux, 1988, Volume: 81 Spec No

    Topics: Adult; Aldosterone; Blood Pressure; Heart Rate; Humans; Hyperaldosteronism; Hypertension; Hypertensi

1988