Page last updated: 2024-11-01

nicardipine and Esophageal Neoplasms

nicardipine has been researched along with Esophageal Neoplasms in 4 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Esophageal Neoplasms: Tumors or cancer of the ESOPHAGUS.

Research Excerpts

ExcerptRelevanceReference
"Nicardipine-induced bradycardia has been reported in experimental animals but not in clinical patients."7.71Profound sinus bradycardia after intravenous nicardipine. ( Ando, H; Arima, H; Katsuya, H; Morishima, T; Sobue, K; Tanaka, S, 2002)
"Esophageal achalasia (EA) is a rare disease in man and animals and there are many discussions on its higher risk of esophageal cancer."5.30High incidence of esophageal cancer in esophageal achalasia by the oral administration of N-amyl-N-methylnitrosamine and its prevention by nicardipine hydrochloride in mice. ( Baskar, R; Fukuda, K; Hongyo, T; Kurooka, M; Li, LY; Matsuda, H; Miyata, M; Nakajima, H; Nomura, T; Sutoh, K, 1998)
"Nicardipine-induced bradycardia has been reported in experimental animals but not in clinical patients."3.71Profound sinus bradycardia after intravenous nicardipine. ( Ando, H; Arima, H; Katsuya, H; Morishima, T; Sobue, K; Tanaka, S, 2002)
"Esophageal achalasia (EA) is a rare disease in man and animals and there are many discussions on its higher risk of esophageal cancer."1.30High incidence of esophageal cancer in esophageal achalasia by the oral administration of N-amyl-N-methylnitrosamine and its prevention by nicardipine hydrochloride in mice. ( Baskar, R; Fukuda, K; Hongyo, T; Kurooka, M; Li, LY; Matsuda, H; Miyata, M; Nakajima, H; Nomura, T; Sutoh, K, 1998)
"Nicardipine and diltiazem were used as the calcium-channel blockers, which were given orally or intravenously."1.27[Cancer chemotherapy combined with a calcium antagonist in patients with hematologic malignancies and solid tumors resistant to standard chemotherapy]. ( Sampi, K, 1987)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Akazawa, S1
Honda, T1
Sampi, K2
Futatsuki, K1
Kurooka, M1
Hongyo, T1
Nakajima, H1
Baskar, R1
Li, LY1
Fukuda, K1
Sutoh, K1
Miyata, M1
Matsuda, H1
Nomura, T1
Arima, H1
Sobue, K1
Tanaka, S1
Morishima, T1
Ando, H1
Katsuya, H1

Other Studies

4 other studies available for nicardipine and Esophageal Neoplasms

ArticleYear
[Combination chemotherapy of nicardipine and vindesine sulfate, cis-diammine dichloroplatinum (II) for patients with advanced esophageal carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Calcium Channel Blockers; Carcinoma, Squamous Cell;

1984
High incidence of esophageal cancer in esophageal achalasia by the oral administration of N-amyl-N-methylnitrosamine and its prevention by nicardipine hydrochloride in mice.
    Cancer letters, 1998, May-15, Volume: 127, Issue:1-2

    Topics: Administration, Oral; Animals; Calcium Channel Blockers; Carcinogens; Carcinoma, Squamous Cell; Esop

1998
Profound sinus bradycardia after intravenous nicardipine.
    Anesthesia and analgesia, 2002, Volume: 95, Issue:1

    Topics: Aged; Arrhythmia, Sinus; Bradycardia; Calcium Channel Blockers; Electrocardiography; Esophageal Neop

2002
[Cancer chemotherapy combined with a calcium antagonist in patients with hematologic malignancies and solid tumors resistant to standard chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:3 Pt 2

    Topics: Acute Disease; Administration, Oral; Antibiotics, Antineoplastic; Diltiazem; Drug Therapy, Combinati

1987