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nicardipine and Esophageal Achalasia

nicardipine has been researched along with Esophageal Achalasia in 1 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Esophageal Achalasia: A motility disorder of the ESOPHAGUS in which the LOWER ESOPHAGEAL SPHINCTER (near the CARDIA) fails to relax resulting in functional obstruction of the esophagus, and DYSPHAGIA. Achalasia is characterized by a grossly contorted and dilated esophagus (megaesophagus).

Research Excerpts

ExcerptRelevanceReference
"Esophageal achalasia (EA) is a rare disease in man and animals and there are many discussions on its higher risk of esophageal cancer."5.30High incidence of esophageal cancer in esophageal achalasia by the oral administration of N-amyl-N-methylnitrosamine and its prevention by nicardipine hydrochloride in mice. ( Baskar, R; Fukuda, K; Hongyo, T; Kurooka, M; Li, LY; Matsuda, H; Miyata, M; Nakajima, H; Nomura, T; Sutoh, K, 1998)
"Esophageal achalasia (EA) is a rare disease in man and animals and there are many discussions on its higher risk of esophageal cancer."1.30High incidence of esophageal cancer in esophageal achalasia by the oral administration of N-amyl-N-methylnitrosamine and its prevention by nicardipine hydrochloride in mice. ( Baskar, R; Fukuda, K; Hongyo, T; Kurooka, M; Li, LY; Matsuda, H; Miyata, M; Nakajima, H; Nomura, T; Sutoh, K, 1998)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kurooka, M1
Hongyo, T1
Nakajima, H1
Baskar, R1
Li, LY1
Fukuda, K1
Sutoh, K1
Miyata, M1
Matsuda, H1
Nomura, T1

Other Studies

1 other study available for nicardipine and Esophageal Achalasia

ArticleYear
High incidence of esophageal cancer in esophageal achalasia by the oral administration of N-amyl-N-methylnitrosamine and its prevention by nicardipine hydrochloride in mice.
    Cancer letters, 1998, May-15, Volume: 127, Issue:1-2

    Topics: Administration, Oral; Animals; Calcium Channel Blockers; Carcinogens; Carcinoma, Squamous Cell; Esop

1998