Page last updated: 2024-11-01

nicardipine and Electrolytes

nicardipine has been researched along with Electrolytes in 7 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Electrolytes: Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed)

Research Excerpts

ExcerptRelevanceReference
"We performed a randomized, crossover study comparing the effects of nicardipine and trichlormethiazide on insulin sensitivity in 8 untreated essential hypertensive patients."9.07Comparison of effects of nicardipine and trichlormethiazide on insulin sensitivity in hypertensive patients. ( Fujita, T; Ishibashi, K; Isogai, Y; Kageyama, S; Mimura, A; Sakurai, T; Yamamoto, J; Yokota, K, 1994)
"Nicardipine treatment significantly reduced Ca2+ accumulation in the middle cerebral artery territory by 60% compared with six untreated rats 6 hours after arterial occlusion."5.27Nicardipine reduces calcium accumulation and electrolyte derangements in regional cerebral ischemia in rats. ( Flamm, ES; Hadani, M; Young, W, 1988)
"We performed a randomized, crossover study comparing the effects of nicardipine and trichlormethiazide on insulin sensitivity in 8 untreated essential hypertensive patients."5.07Comparison of effects of nicardipine and trichlormethiazide on insulin sensitivity in hypertensive patients. ( Fujita, T; Ishibashi, K; Isogai, Y; Kageyama, S; Mimura, A; Sakurai, T; Yamamoto, J; Yokota, K, 1994)
" Parameters measured included blood pressure, blood chemistry (serum creatinine, uric acid, blood urea nitrogen, blood glucose total cholesterol, and electrolytes), plasma renin activity, and plasma aldosterone concentration."3.67Effects of nicardipine on blood pressure and renal function in elderly hypertensive patients with renal dysfunction. ( Saruta, T, 1989)
"The effects of a calcium antagonist [Nicardipine hydrochloride (NH)] on the prostaglandin [prostaglandin E2 (PGE2), and 6-keto-prostaglandin F1 alpha (6-keto-PGF1 alpha)] and thromboxane B2 levels in the blood and urine were examined in 6 patients with essential hypertension following intravenous infusion of NH for 120 minutes."3.67Effects of intravenous administration of a calcium antagonist on prostaglandins and thromboxane in plasma and urine in humans. ( Fukuda, N; Hatano, M; Honda, M; Izumi, Y; Manabe, R; Minato, M; Watanabe, M, 1986)
"Nicardipine treatment significantly reduced Ca2+ accumulation in the middle cerebral artery territory by 60% compared with six untreated rats 6 hours after arterial occlusion."1.27Nicardipine reduces calcium accumulation and electrolyte derangements in regional cerebral ischemia in rats. ( Flamm, ES; Hadani, M; Young, W, 1988)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's2 (28.57)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kageyama, S1
Yamamoto, J1
Mimura, A1
Ishibashi, K1
Sakurai, T1
Yokota, K1
Isogai, Y1
Fujita, T1
Yokoyama, T1
Masuda, Y1
Sakai, T1
Tanaka, S1
Tomita, K1
Nagaoka, A1
Shibota, M1
Saruta, T1
Hadani, M1
Young, W1
Flamm, ES1
Smith, SA1
Rafiqi, EI1
Gardener, EG1
Young, MA1
Littler, WA1
Honda, M1
Manabe, R1
Minato, M1
Watanabe, M1
Fukuda, N1
Izumi, Y1
Hatano, M1

Trials

1 trial available for nicardipine and Electrolytes

ArticleYear
Comparison of effects of nicardipine and trichlormethiazide on insulin sensitivity in hypertensive patients.
    American journal of hypertension, 1994, Volume: 7, Issue:5

    Topics: Adult; Blood Pressure; Electrolytes; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hypert

1994

Other Studies

6 other studies available for nicardipine and Electrolytes

ArticleYear
Effects of NZ-105, a new calcium antagonist, on renal function in anesthetized spontaneously hypertensive rats.
    Journal of cardiovascular pharmacology, 1992, Volume: 19, Issue:6

    Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyrid

1992
Natriuretic action of manidipine hydrochloride, a new calcium channel blocker, in spontaneously hypertensive rats.
    Japanese journal of pharmacology, 1989, Volume: 51, Issue:2

    Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Electrolytes; Male; Natriuresis; Nicardipine; N

1989
Effects of nicardipine on blood pressure and renal function in elderly hypertensive patients with renal dysfunction.
    American heart journal, 1989, Volume: 117, Issue:1

    Topics: Aged; Aldosterone; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Cholesterol; Creatinine; Elec

1989
Nicardipine reduces calcium accumulation and electrolyte derangements in regional cerebral ischemia in rats.
    Stroke, 1988, Volume: 19, Issue:9

    Topics: Animals; Body Water; Brain; Brain Ischemia; Calcium; Carbon Radioisotopes; Electrolytes; Ions; Nicar

1988
Renal effects of nicardipine in essential hypertension: differences between acute and chronic therapy.
    Journal of hypertension, 1987, Volume: 5, Issue:6

    Topics: Adult; Blood Pressure; Diuresis; Drug Administration Schedule; Electrolytes; Female; Glomerular Filt

1987
Effects of intravenous administration of a calcium antagonist on prostaglandins and thromboxane in plasma and urine in humans.
    Prostaglandins, leukotrienes, and medicine, 1986, Volume: 23, Issue:2-3

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aldosterone; Blood Pressure; Calcium Channel Blockers; Dinopros

1986