nicardipine has been researched along with Diabetic Nephropathies in 4 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
Diabetic Nephropathies: KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the renal effects of nicardipine, a calcium entry blocker, in eight patients with essential hypertension (group A, WHO I or II), six hypertensive type II diabetics with mild-to-moderate nephropathy (group B, urinary albumin 200-789 mg/day), and six hypertensive type II diabetics with severe or advanced nephropathy (group C, urinary albumin 1,596-4,300 mg/day)." | 5.06 | Renal effects of nicardipine, a calcium entry blocker, in hypertensive type II diabetic patients with nephropathy. ( Aoyagi, K; Baba, T; Ido, Y; Ishizaki, T; Murabayashi, S; Takebe, K, 1986) |
| "The renal effects of oral maintenance doses of nicardipine 60-120 mg/day have been studied in 18 hypertensive patients with Type 2 (non-insulin-dependent) diabetes mellitus: 6 with normoalbuminuria (urinary albumin excretion rate, AER less than 20 micrograms." | 3.68 | Renal effects of nicardipine, a calcium antagonist, in hypertensive type 2 (non-insulin-dependent) diabetic patients with and without nephropathy. ( Baba, T; Murabayashi, S; Takebe, K; Tomiyama, T, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sato, Y | 1 |
| Iwase, M | 1 |
| Wakisaka, M | 1 |
| Yoshizumi, H | 1 |
| Nunoi, K | 1 |
| Yoshinari, M | 1 |
| Fujishima, M | 1 |
| Baba, T | 2 |
| Tomiyama, T | 1 |
| Murabayashi, S | 2 |
| Takebe, K | 2 |
| Stornello, M | 1 |
| Valvo, EV | 1 |
| Scapellato, L | 1 |
| Ishizaki, T | 1 |
| Ido, Y | 1 |
| Aoyagi, K | 1 |
2 trials available for nicardipine and Diabetic Nephropathies
| Article | Year |
|---|---|
Hemodynamic, renal, and humoral effects of the calcium entry blocker nicardipine and converting enzyme inhibitor captopril in hypertensive type II diabetic patients with nephropathy.
Topics: Adult; Blood Pressure; Captopril; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Combinatio | 1989 |
Renal effects of nicardipine, a calcium entry blocker, in hypertensive type II diabetic patients with nephropathy.
Topics: Adult; Albuminuria; Clinical Trials as Topic; Diabetic Nephropathies; Female; Glomerular Filtration | 1986 |
2 other studies available for nicardipine and Diabetic Nephropathies
| Article | Year |
|---|---|
Renoprotective effect of enalapril in uninephrectomized spontaneously hypertensive rats with neonatal streptozotocin-induced diabetes.
Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Antihyper | 1995 |
Renal effects of nicardipine, a calcium antagonist, in hypertensive type 2 (non-insulin-dependent) diabetic patients with and without nephropathy.
Topics: Albuminuria; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glomerular Filtration Rate; | 1990 |