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nicardipine and Dementia, Vascular

nicardipine has been researched along with Dementia, Vascular in 3 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Dementia, Vascular: An imprecise term referring to dementia associated with CEREBROVASCULAR DISORDERS, including CEREBRAL INFARCTION (single or multiple), and conditions associated with chronic BRAIN ISCHEMIA. Diffuse, cortical, and subcortical subtypes have been described. (From Gerontol Geriatr 1998 Feb;31(1):36-44)

Research Excerpts

ExcerptRelevanceReference
"Treatment with nicardipine countered microanatomical changes occurring in SHR, whereas hydralazine displayed a less pronounced effect."5.32Treatment with nicardipine protects brain in an animal model of hypertension-induced damage. ( Amenta, F; Tomassoni, D, 2004)
"Nicardipine is a dihydropyridine-type Ca(2+) channel blocker (CCB) with strong antihypertensive activity and with a peculiar cerebrovascular profile."2.45Nicardipine use in cerebrovascular disease: a review of controlled clinical studies. ( Amenta, F; Lanari, A; Mignini, F; Silvestrelli, G; Tomassoni, D; Traini, E, 2009)
"Nicardipine is a dihydropyridine-type calcium channel blocker (CCB) with a peculiar cerebrovascular profile developed approximately 30 years ago."2.44Nicardipine: a hypotensive dihydropyridine-type calcium antagonist with a peculiar cerebrovascular profile. ( Amenta, F; Mignini, F; Tomassoni, D; Traini, E; Veglio, F, 2008)
"Treatment with nicardipine countered microanatomical changes occurring in SHR, whereas hydralazine displayed a less pronounced effect."1.32Treatment with nicardipine protects brain in an animal model of hypertension-induced damage. ( Amenta, F; Tomassoni, D, 2004)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amenta, F3
Tomassoni, D3
Traini, E2
Mignini, F2
Veglio, F1
Lanari, A1
Silvestrelli, G1

Reviews

2 reviews available for nicardipine and Dementia, Vascular

ArticleYear
Nicardipine: a hypotensive dihydropyridine-type calcium antagonist with a peculiar cerebrovascular profile.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2008, Volume: 30, Issue:8

    Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cerebrovascular Disorders; Dement

2008
Nicardipine use in cerebrovascular disease: a review of controlled clinical studies.
    Journal of the neurological sciences, 2009, Aug-15, Volume: 283, Issue:1-2

    Topics: Antihypertensive Agents; Calcium Channel Blockers; Cerebrovascular Disorders; Cognition; Cognition D

2009

Other Studies

1 other study available for nicardipine and Dementia, Vascular

ArticleYear
Treatment with nicardipine protects brain in an animal model of hypertension-induced damage.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2004, Volume: 26, Issue:4

    Topics: Animals; Antihypertensive Agents; Astrocytes; Blood Pressure; Dementia, Vascular; Disease Models, An

2004