nicardipine has been researched along with Decerebrate Posturing in 5 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of two dihydropyridine type calcium entry blockers, nilvadipine and nicardipine hydrochloride (nicardipine), on the liberation of free fatty acids (FFAs) were investigated using an experimental model of global cerebral ischemia in rats, and were compared with their pharmacokinetic properties." | 7.68 | Nilvadipine as a neuroprotective calcium entry blocker in a rat model of global cerebral ischemia. A comparative study with nicardipine hydrochloride. ( Fujiwara, T; Kohsaka, M; Mori, J; Satoh, H; Sogabe, K; Takakura, S; Tokuma, Y; Totsuka, Z, 1992) |
| "The effects of two dihydropyridine type calcium entry blockers, nilvadipine and nicardipine hydrochloride (nicardipine), on the liberation of free fatty acids (FFAs) were investigated using an experimental model of global cerebral ischemia in rats, and were compared with their pharmacokinetic properties." | 3.68 | Nilvadipine as a neuroprotective calcium entry blocker in a rat model of global cerebral ischemia. A comparative study with nicardipine hydrochloride. ( Fujiwara, T; Kohsaka, M; Mori, J; Satoh, H; Sogabe, K; Takakura, S; Tokuma, Y; Totsuka, Z, 1992) |
| "Using a model of global cerebral ischemia in rats, we examined the effects of a dihydropyridine Ca2+ antagonist, nicardipine, on the liberation of free fatty acids (FFAs)." | 3.67 | Ca2+ antagonist and protection of the brain against ischemia. Effects of nicardipine on free fatty acid liberation in the ischemic brain in rats. ( Handa, J; Kidooka, M; Matsuda, M, 1987) |
| " Endotoxin impaired responsiveness to vasopressin, phenylephrine and cirazoline, producing a shift to the right in the dose-response curves without any change in the maximum response." | 1.28 | Endotoxin-induced impairment of vasopressor and vasodepressor responses in the pithed rat. ( Furman, BL; Guc, MO; Parratt, JR, 1990) |
| " In rats treated with the ganglionic blocking agent, pentolinium, nicardipine produced parallel shifts to the right in the dose-response curves for phenylephrine but had no effect on maximal responses to phenylephrine." | 1.27 | Greater vasodepressor sensitivity to nicardipine in spontaneously hypertensive rats (SHR) compared to normotensive rats. ( Armstrong, JM; Atkinson, J; Boillat, N; de Rivaz, JC; Fluckiger, JP; Fouda, AK; Piton, MC; Porchet, PA; Sautel, M; Sonnay, M, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shudo, C | 1 |
| Masuda, Y | 1 |
| Sakai, T | 1 |
| Tanaka, S | 1 |
| Shigenobu, K | 1 |
| Kasuya, Y | 1 |
| Takakura, S | 1 |
| Sogabe, K | 1 |
| Satoh, H | 1 |
| Mori, J | 1 |
| Fujiwara, T | 1 |
| Totsuka, Z | 1 |
| Tokuma, Y | 1 |
| Kohsaka, M | 1 |
| Guc, MO | 1 |
| Furman, BL | 1 |
| Parratt, JR | 1 |
| Atkinson, J | 1 |
| Sautel, M | 1 |
| Sonnay, M | 1 |
| Fluckiger, JP | 1 |
| de Rivaz, JC | 1 |
| Boillat, N | 1 |
| Piton, MC | 1 |
| Porchet, PA | 1 |
| Armstrong, JM | 1 |
| Fouda, AK | 1 |
| Kidooka, M | 1 |
| Matsuda, M | 1 |
| Handa, J | 1 |
5 other studies available for nicardipine and Decerebrate Posturing
| Article | Year |
|---|---|
Studies on the hypotensive mechanisms of NZ-105, a new dihydropyridine derivative, in rats and rabbits.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Decerebrate State; Dihydropyridines; Male; Nicardi | 1993 |
Nilvadipine as a neuroprotective calcium entry blocker in a rat model of global cerebral ischemia. A comparative study with nicardipine hydrochloride.
Topics: Animals; Brain; Brain Ischemia; Calcium Channel Blockers; Decerebrate State; Fatty Acids, Nonesterif | 1992 |
Endotoxin-induced impairment of vasopressor and vasodepressor responses in the pithed rat.
Topics: Animals; Blood Pressure; Decerebrate State; Dose-Response Relationship, Drug; Endothelins; Endotoxin | 1990 |
Greater vasodepressor sensitivity to nicardipine in spontaneously hypertensive rats (SHR) compared to normotensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Brimonidine Tartrate; Decerebrate State; Hemodynam | 1988 |
Ca2+ antagonist and protection of the brain against ischemia. Effects of nicardipine on free fatty acid liberation in the ischemic brain in rats.
Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Decerebrate State; Fatty Acids, Nonesterified; Ma | 1987 |