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nicardipine and Coronary Disease

nicardipine has been researched along with Coronary Disease in 72 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Research Excerpts

ExcerptRelevanceReference
"Nicardipine treatment has been evaluated in patients with chronic stable effort angina or with angina at rest due to coronary spasm."7.76Usefulness of nicardipine for angina pectoris. ( Lambert, CR; Pepine, CJ, 1987)
"The efficacy of nicardipine and nitroprusside in preventing poststernotomy hypertension was compared in two groups of 45 patients undergoing coronary artery surgery."7.67The efficacy of nicardipine and nitroprusside in preventing poststernotomy hypertension. ( Deen, L; Dijkhuis, JP; Koolen, JJ; Leyssius, AT; Meyne, NG; van Wezel, HB; Vergroesen, I; Visser, CA, 1989)
"To examine whether nicardipine, a dihydropyridine derivative, limits size of myocardial infarction, and to compare the protective effects of nicardipine administered before and early and late after coronary artery occlusion, 99mTc-labeled albumin microspheres were injected into the left atrium during 5 min temporary coronary artery occlusion to determine the extent of the hypoperfused zone (the area at risk)."7.67Comparative effects of nicardipine, a new calcium antagonist, on size of myocardial infarction after coronary artery occlusion in dogs. ( Endo, T; Fujita, S; Hayakawa, H; Iida, N; Kikuchi, K; Kiuchi, K; Nejima, J; Okumura, H, 1986)
"Nicardipine is a potent coronary and systemic vasodilating drug that improves exercise tolerance and myocardial metabolic response to pacing stress, the mechanism for which appears to be partially mediated through increased coronary blood flow."5.27Effects of nicardipine on exercise- and pacing-induced myocardial ischemia in angina pectoris. ( Feldman, RL; Hill, JA; Lambert, CR; Pepine, CJ, 1987)
"We assessed the efficacy of a continuous infusion of nicardipine and nitroglycerin in reducing the incidence and severity of perioperative myocardial ischemia during elective coronary artery bypass grafting procedures in a prospective, randomized, controlled study."5.09Antiischemic effects of nicardipine and nitroglycerin after coronary artery bypass grafting. ( Apostolidou, IA; Despotis, GJ; Hauptmann, EL; Hogue, CW; Lappas, DG; McCawley, CA; Skubas, NJ, 1999)
"The new calcium antagonist nicardipine (barizine) was tested for effects on platelet function and transient myocardial ischemia in 23 patients with coronary heart disease."5.07[Characteristics of nicardipine treatment of patients with ischemic heart disease]. ( Barinov, VG; Galichenko, IV; Makarovskiĭ, VV; Martynov, AI; Styrova, TK; Vertkin, AL; Zharov, EI, 1991)
"Altogether 12 patients with stable angina pectoris of effort were examined for the efficacy of nicardipine as compared to nifedipine and placebo by means of pharmacodynamic studies using treadmill."5.06[The comparative efficacy of nicardipine and nifedipine in stenocardia patients]. ( Martsevich, SIu; Metelitsa, VI; Simkhaev, LS; Slastnikova, ID, 1990)
"The efficacy of nicardipine vs nitroprusside in controlling hypertension after sternotomy was compared in 120 patients undergoing coronary artery bypass grafting and anesthetized with fentanyl (100 micrograms/kg)."5.06Antihypertensive and anti-ischemic effects of nicardipine and nitroprusside in patients undergoing coronary artery bypass grafting. ( Deen, L; Dijkhuis, JP; Koolen, JJ; Moulijn, AC; van Wezel, HB; Vergroesen, I; Visser, CA, 1989)
"We have used a modified noninvasive echo-Doppler cardiac output device, based on the principle of attenuated compensation volume flow, to assess the cardiovascular effects of the slow-calcium antagonist nicardipine in coronary disease."5.06Hemodynamic assessment of nicardipine alone and with atenolol in coronary artery disease using a modified echo-Doppler device. ( Silke, B; Taylor, SH; Verma, SP; Zezulka, AV, 1989)
"Nicardipine treatment has been evaluated in patients with chronic stable effort angina or with angina at rest due to coronary spasm."3.76Usefulness of nicardipine for angina pectoris. ( Lambert, CR; Pepine, CJ, 1987)
"Hepatic function was studied in 31 patients with coronary heart disease before and after treatment with nicardipine."3.68[Effects of nicardipine on the functional state of the liver in patients with ischemic heart disease]. ( Makarovskiĭ, VV; Makeeva, LG; Martynov, AI; Shafranskiĭ, IuA; Svetova, SD; Vertkin, AL, 1991)
"To assess the effect of nicardipine on left ventricular (LV) diastolic function independent of concurrent effects on loading conditions in patients with LV systolic dysfunction due to coronary artery disease, equihypotensive doses of intravenous nitroprusside and nicardipine were administered to 12 patients with congestive heart failure due to previous myocardial infarction (LV ejection fraction less than 0."3.68Left ventricular diastolic function in patients with left ventricular systolic dysfunction due to coronary artery disease and effect of nicardipine. ( Aroney, CN; Boucher, CA; Dec, GW; Fifer, MA; Semigran, MJ, 1991)
"The efficacy of nicardipine and nitroprusside in preventing poststernotomy hypertension was compared in two groups of 45 patients undergoing coronary artery surgery."3.67The efficacy of nicardipine and nitroprusside in preventing poststernotomy hypertension. ( Deen, L; Dijkhuis, JP; Koolen, JJ; Leyssius, AT; Meyne, NG; van Wezel, HB; Vergroesen, I; Visser, CA, 1989)
"Pharmacokinetic, haemodynamic and radionuclide studies explored the acute pharmacokinetic and pharmacodynamic actions of nicardipine in patients with coronary heart disease."3.67Pharmacokinetic, haemodynamic and radionuclide studies with nicardipine in coronary artery disease. ( Finlayson, JR; Frais, MA; Graham, DJ; Reynolds, G; Silke, B; Taylor, SH; Verma, SP, 1986)
"To examine whether nicardipine, a dihydropyridine derivative, limits size of myocardial infarction, and to compare the protective effects of nicardipine administered before and early and late after coronary artery occlusion, 99mTc-labeled albumin microspheres were injected into the left atrium during 5 min temporary coronary artery occlusion to determine the extent of the hypoperfused zone (the area at risk)."3.67Comparative effects of nicardipine, a new calcium antagonist, on size of myocardial infarction after coronary artery occlusion in dogs. ( Endo, T; Fujita, S; Hayakawa, H; Iida, N; Kikuchi, K; Kiuchi, K; Nejima, J; Okumura, H, 1986)
"Orthostatic hypotension is a dangerous problem in elderly patients, often exacerbated by vasodilator medications."2.68Cardiovascular adaptation to orthostatic stress during vasodilator therapy. ( Abernethy, D; Connelly, CM; Kelley-Gagnon, M; Kiely, DK; Lipsitz, LA; Waksmonski, C, 1996)
" After a stable control period, dose-response curves were constructed for each drug with hemodynamics measured 10 minutes after intravenous boluses."2.66Comparative hemodynamic dose-response effects of five slow calcium channel-blocking agents in coronary artery disease. ( Frais, MA; Jackson, N; Midtbo, KA; Reynolds, G; Sharma, S; Silke, B; Taylor, SH; Verma, SP, 1987)
"Nicardipine or saline was randomly infused during the first or second pacing."2.66Effects of intracoronary infusion of nicardipine during silent ischaemia on myocardial metabolism and function. ( Caucheteux, D; Gurné, O; Hanet, C; Hue, L; Pouleur, H; Rousseau, MF, 1988)
"Nicardipine has high affinity for the dihydropyridine-binding site and has been shown to inhibit the influx of extracellular calcium through membrane slow channels."2.37Animal pharmacology of nicardipine and its clinical relevance. ( Whiting, RL, 1987)
"Nicardipine is a powerful systemic vasodilator with minimal effects on myocardial inotropic state, even in patients with compromised left ventricular function and patients receiving beta blocker therapy."2.37Hemodynamics of nicardipine in coronary artery disease. ( Dunning, AJ; Koolen, JJ; van Wezel, H; Visser, CA, 1987)
"Nicardipine was administered as a 2 mg bolus followed by an infusion, titrated to maintain a 10 to 20 mm Hg decrease in systolic arterial pressure."1.28Acute antianginal hemodynamic effects of nicardipine in coronary artery disease. ( Lambert, CR; Pepine, CJ, 1990)
"Nicardipine-based treatment is therefore effective, safe, and well tolerated in elderly hypertensive patients with concomitant disease."1.28The clinical performance of nicardipine in elderly hypertensive patients with concomitant diseases. ( Leonetti, G, 1989)
"Nicardipine is a powerful arteriodilator without detectable negative inotropic effects and prolongs the time to pacing induced angina."1.27Effect of nicardipine on left ventricular function and on angina induced by atrial pacing in patients with coronary artery disease. ( Lipkin, DP; Poole-Wilson, PA, 1985)
"Nicardipine is a potent coronary and systemic vasodilating drug that improves exercise tolerance and myocardial metabolic response to pacing stress, the mechanism for which appears to be partially mediated through increased coronary blood flow."1.27Effects of nicardipine on exercise- and pacing-induced myocardial ischemia in angina pectoris. ( Feldman, RL; Hill, JA; Lambert, CR; Pepine, CJ, 1987)
"Nicardipine was administered as a 2 mg bolus (i."1.27Effects of nicardipine on left ventricular function and energetics in man. ( Feldman, RL; Hill, JA; Lambert, CR; Pepine, CJ, 1986)
"When nicardipine (0."1.27Effects of nicardipine on ischemic mechanical failure and tissue injury in isolated perfused rat heart. ( Noshiro, O; Ohhata, I; Ohta, A; Shikama, H, 1985)
"The haemodynamic dose-response effects of the slow channel blocking agent nicardipine were evaluated in 10 male patients with angiographically confirmed coronary artery disease."1.27Haemodynamic dose-response effects of i.v. nicardipine in coronary artery disease. ( Hussain, M; Nelson, GI; Silke, B; Taylor, SH; Verma, SP, 1984)
"Nicardipine is a potent vasodilator, which produced a marked reduction of systemic vascular resistance and left ventricular end-diastolic pressure during exercise."1.27Immediate and longer-term effects of nicardipine, at rest and during exercise, in patients with coronary artery disease. ( Jaarsma, W; Kan, G; Lie, KI; Visser, CA, 1984)
"nicardipine was given to 9 patients with coronary artery disease, pretreated with propranolol (0."1.27Effects of nicardipine or nifedipine added to propranolol in patients with coronary artery disease. ( Brasseur, LA; Charlier, AA; Etienne, J; Pouleur, H; Rousseau, MF; Van Eyll, C; Van Mechelen, H, 1984)

Research

Studies (72)

TimeframeStudies, this research(%)All Research%
pre-199047 (65.28)18.7374
1990's21 (29.17)18.2507
2000's4 (5.56)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Casthely, PA2
Bunik, T1
Yoganathan, T1
Komer, C1
Mekhjian, H1
Silke, B6
Verma, SP6
Nelson, GI1
Hussain, M1
Taylor, SH6
Lipkin, D1
Poole-Wilson, PA2
Visser, CA5
Jaarsma, W2
Kan, G2
Lie, KI2
Pouleur, H5
Etienne, J1
Van Mechelen, H1
Van Eyll, C3
Charlier, AA3
Brasseur, LA1
Rousseau, MF5
Sunamori, M1
Okamura, T1
Amano, J1
Suzuki, A1
Hopf, R1
Becker, HJ1
Kober, G1
Dowinsky, S1
Kaltenbach, M1
Nakaya, H1
Kanno, M1
Kaufmann, P1
Vassalli, G1
Utzinger, U1
Hess, OM1
Lam, JY1
Latour, JG1
Lespérance, J2
Waters, D2
Nomura, M1
Miura, Y1
Uchida, K1
Nagasawa, C1
Takahashi, K1
Kawai, N1
Nomura, Y1
Fujita, M1
Suzuki, H1
Lambert, CR9
Grady, T1
Hashimi, W1
Blakely, M1
Panayioutou, H1
Lipsitz, LA1
Connelly, CM1
Kelley-Gagnon, M1
Kiely, DK1
Abernethy, D1
Waksmonski, C1
Apostolidou, IA1
Despotis, GJ1
Hogue, CW1
Skubas, NJ1
McCawley, CA1
Hauptmann, EL1
Lappas, DG1
Fugit, MD1
Rubal, BJ1
Donovan, DJ1
Williams, MJ1
Low, CJ1
Wilkins, GT1
Stewart, RA1
Chanda, J1
Canver, CC1
Engberding, R1
Reinbach, R1
Frommelt, T1
Zezulka, AV2
Sharma, S2
Goldhammer, E1
Jackson, N3
Makeeva, LG1
Svetova, SD1
Martynov, AI3
Vertkin, AL3
Makarovskiĭ, VV2
Shafranskiĭ, IuA1
Timour, Q1
Larbre, JP1
Aupetit, JF1
Gerentes-Chassagne, I1
Loufoua-Moundanga, J1
Kioueh, I1
Faucon, G1
Tamburino, C1
Russo, G1
Di Paola, R1
Passaniti, A1
Zisa, MB1
Felis, S1
Calvi, V1
Alì, A1
Cinnirella, C1
Giuffrida, G1
Zharov, EI2
Styrova, TK2
Galichenko, IV2
Barinov, VG1
Hano, O1
Silverman, HS1
Blank, PS1
Mellits, ED1
Baumgardner, R1
Lakatta, EG1
Stern, MD1
Aroney, CN1
Semigran, MJ1
Dec, GW1
Boucher, CA1
Fifer, MA1
Sedov, VP1
Rocha, P2
Guerret, M1
David, D2
Marchand, X1
Kahn, JC2
Slastnikova, ID1
Martsevich, SIu1
Simkhaev, LS1
Metelitsa, VI1
Markham, A1
Morgan, RM1
Sweetman, AJ1
Pepine, CJ8
Tachibana, H1
Whiting, RL1
Feldman, RL5
MacDonald, RG1
Hill, JA5
Horiuchi, K1
van Wezel, HB2
Koolen, JJ4
Vergroesen, I2
Leyssius, AT1
Dijkhuis, JP2
Meyne, NG1
Deen, L2
Zadionchenko, VS1
Kamenker, ES1
Chikvashvili, IA1
Baba, A1
Arita, M1
Masuyama, Y1
Moulijn, AC1
McCarthy, G1
Kenny, D1
Lipkin, DP1
Leonetti, G1
Di Biase, M1
Massari, V1
Amodio, G1
Favale, S1
Rizzon, P1
Hanet, C3
Vincent, MF1
Lavenne-Pardonge, E1
Bélichard, P1
Pruneau, D1
Rochette, L1
Frais, MA3
Midtbo, KA1
Reynolds, G3
Custro, N1
Scafidi, V1
Berland, J1
Savin, T1
Saoudi, N1
Cribier, A1
Letac, B1
Prida, XE1
Gurné, O2
Hue, L1
Caucheteux, D1
Rodrigues, EA2
Kohli, RS1
Hains, AD1
Lahiri, A2
Raftery, EB2
van Wezel, H1
Dunning, AJ1
Thomassen, AR1
Bagger, JP1
Nielsen, TT1
Miyamori, R1
Nakamura, Y1
Mori, H1
Miyazaki, T1
Kojima, S1
Abe, S1
Takahashi, M1
Hattori, S1
Imai, H1
Matsui, K1
Ochi, S1
Nakazawa, M1
Nakagawa, Y1
Imai, S1
Freedman, D1
Theroux, P1
Lemarbre, L1
Kamm, B1
Joyal, M1
Dyrda, I1
Gosselin, G1
Hudon, G1
Graham, DJ1
Finlayson, JR1
Endo, T1
Nejima, J1
Fujita, S1
Kiuchi, K1
Iida, N1
Kikuchi, K1
Hayakawa, H1
Okumura, H1
Bongrani, S1
Schiantarelli, P1
Acerbi, D1
Ciampalini, G1
Ferrari, R1
Zannier, D1
Baron, B1
Pathe, M1
Shikama, H1
Noshiro, O1
Ohta, A1
Ohhata, I1

Reviews

6 reviews available for nicardipine and Coronary Disease

ArticleYear
[Treatment of angina pectoris with calcium antagonists].
    Herz, 1982, Volume: 7, Issue:4

    Topics: Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Diltiazem; Drug Therapy, Combination; E

1982
Cardiovascular effects of nicardipine.
    Angiology, 1990, Volume: 41, Issue:11 Pt 2

    Topics: Animals; Arrhythmias, Cardiac; Cardiovascular System; Coronary Disease; Heart; Heart Failure; Hemody

1990
Animal pharmacology of nicardipine and its clinical relevance.
    The American journal of cardiology, 1987, Jun-30, Volume: 59, Issue:17

    Topics: Action Potentials; Animals; Calcium; Coronary Disease; Dose-Response Relationship, Drug; Drug Evalua

1987
Effects of nicardipine on coronary blood flow.
    American heart journal, 1988, Volume: 116, Issue:1 Pt 1

    Topics: Animals; Coronary Circulation; Coronary Disease; Coronary Vessels; Hemodynamics; Humans; Muscle, Smo

1988
Usefulness of nicardipine for angina pectoris.
    The American journal of cardiology, 1987, Jun-30, Volume: 59, Issue:17

    Topics: Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Heart; Humans; Myocardium; Nicardipine;

1987
Hemodynamics of nicardipine in coronary artery disease.
    The American journal of cardiology, 1987, Jun-30, Volume: 59, Issue:17

    Topics: Coronary Disease; Coronary Vessels; Dose-Response Relationship, Drug; Drug Evaluation; Hemodynamics;

1987

Trials

22 trials available for nicardipine and Coronary Disease

ArticleYear
Nicardipine or nitroglycerin in patients with failed percutaneous coronary angioplasty: effect on myocardial diastolic function.
    Journal of cardiothoracic and vascular anesthesia, 2003, Volume: 17, Issue:5

    Topics: Adult; Angioplasty, Balloon, Coronary; Biomarkers; Blood Flow Velocity; Calcium Channel Blockers; Co

2003
Effect of nicardipine on myocardial contractility and on angina induced by atrial pacing in patients with coronary artery disease (abstract).
    Postgraduate medical journal, 1984, Volume: 60 Suppl 4

    Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Cardiac Pacing, Artificial;

1984
Platelet aggregation, coronary artery disease progression and future coronary events.
    The American journal of cardiology, 1994, Feb-15, Volume: 73, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; beta-Thromboglobulin; Coronary Angiography; Coronary Disease; Double-B

1994
Hemodynamic and angiographic comparison of intravenous nitroglycerin and nicardipine mainly in subjects without coronary artery disease.
    The American journal of cardiology, 1993, Feb-15, Volume: 71, Issue:5

    Topics: Adult; Aged; Cardiac Catheterization; Chest Pain; Coronary Angiography; Coronary Circulation; Corona

1993
Cardiovascular adaptation to orthostatic stress during vasodilator therapy.
    Clinical pharmacology and therapeutics, 1996, Volume: 60, Issue:4

    Topics: Aged; Aged, 80 and over; Coronary Disease; Cross-Over Studies; Double-Blind Method; Echocardiography

1996
Antiischemic effects of nicardipine and nitroglycerin after coronary artery bypass grafting.
    The Annals of thoracic surgery, 1999, Volume: 67, Issue:2

    Topics: Aged; Coronary Artery Bypass; Coronary Disease; Dose-Response Relationship, Drug; Electrocardiograph

1999
Effects of intracoronary nicardipine, diltiazem and verapamil on coronary blood flow.
    The Journal of invasive cardiology, 2000, Volume: 12, Issue:2

    Topics: Aged; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Coronary Vessels; Diltiazem;

2000
Randomised comparison of the effects of nicardipine and esmolol on coronary artery wall stress: implications for the risk of plaque rupture.
    Heart (British Cardiac Society), 2000, Volume: 84, Issue:4

    Topics: Adrenergic beta-Antagonists; Aged; Blood Pressure; Calcium Channel Blockers; Coronary Angiography; C

2000
How does posture influence the haemodynamic assessment of a cardiovascular drug? Experience with nicardipine.
    Journal of cardiovascular pharmacology, 1990, Volume: 16, Issue:1

    Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Cardiac Output; Cardiovascular Agents; Coronary Diseas

1990
[Characteristics of nicardipine treatment of patients with ischemic heart disease].
    Kardiologiia, 1991, Volume: 31, Issue:3

    Topics: Adult; Coronary Disease; Humans; Male; Middle Aged; Nicardipine; Platelet Aggregation; Platelet Aggr

1991
[The comparative efficacy of nicardipine and nifedipine in stenocardia patients].
    Terapevticheskii arkhiv, 1990, Volume: 62, Issue:10

    Topics: Angina Pectoris; Chronic Disease; Coronary Disease; Electrocardiography; Exercise Test; Humans; Male

1990
Antihypertensive and anti-ischemic effects of nicardipine and nitroprusside in patients undergoing coronary artery bypass grafting.
    The American journal of cardiology, 1989, Oct-17, Volume: 64, Issue:15

    Topics: Aged; Clinical Trials as Topic; Coronary Artery Bypass; Coronary Disease; Electrocardiography; Fenta

1989
Hemodynamic assessment of nicardipine alone and with atenolol in coronary artery disease using a modified echo-Doppler device.
    The American journal of cardiology, 1989, Oct-17, Volume: 64, Issue:15

    Topics: Adult; Aged; Atenolol; Coronary Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination

1989
Myocardial protection by intracoronary nicardipine administration during percutaneous transluminal coronary angioplasty.
    The American journal of cardiology, 1987, May-01, Volume: 59, Issue:12

    Topics: Angina Pectoris; Angioplasty, Balloon; Coronary Disease; Coronary Vessels; Epoprostenol; Humans; Hyp

1987
Comparative hemodynamic dose-response effects of five slow calcium channel-blocking agents in coronary artery disease.
    Clinical pharmacology and therapeutics, 1987, Volume: 42, Issue:4

    Topics: Amlodipine; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Diltiazem; Dose-Re

1987
[Effects of chronic administration of several calcium antagonists on pituitary release of TSH].
    La Clinica terapeutica, 1987, Aug-31, Volume: 122, Issue:4

    Topics: Adult; Atenolol; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Humans; Hyper

1987
Effects of intracoronary infusion of nicardipine during silent ischaemia on myocardial metabolism and function.
    European heart journal, 1988, Volume: 9 Suppl N

    Topics: Adult; Aged; Angina Pectoris; Cardiac Catheterization; Coronary Disease; Glutamine; Heart; Hemodynam

1988
Comparison of nicardipine and verapamil in the management of chronic stable angina.
    International journal of cardiology, 1988, Volume: 18, Issue:3

    Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Double-Bli

1988
Usefulness of nicardipine for angina pectoris.
    The American journal of cardiology, 1987, Jun-30, Volume: 59, Issue:17

    Topics: Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Heart; Humans; Myocardium; Nicardipine;

1987
Improvement in left ventricular diastolic function in patients with stable angina after chronic treatment with verapamil and nicardipine.
    European heart journal, 1987, Volume: 8, Issue:6

    Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Diastole; Double-Blind Method; Female; Heart Functio

1987
Design features of a controlled clinical trial to assess the effect of a calcium entry blocker upon the progression of coronary artery disease.
    Controlled clinical trials, 1987, Volume: 8, Issue:3

    Topics: Adult; Aged; Angiocardiography; Clinical Trials as Topic; Coronary Artery Disease; Coronary Disease;

1987
Haemodynamic analysis of the effects of nicardipine and metoprolol alone and in combination in coronary artery disease.
    European heart journal, 1985, Volume: 6, Issue:11

    Topics: Adult; Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Drug Therapy, Combination; Femal

1985

Other Studies

45 other studies available for nicardipine and Coronary Disease

ArticleYear
Haemodynamic dose-response effects of i.v. nicardipine in coronary artery disease.
    British journal of clinical pharmacology, 1984, Volume: 18, Issue:5

    Topics: Adult; Calcium Channel Blockers; Coronary Disease; Dose-Response Relationship, Drug; Heart; Hemodyna

1984
Immediate and longer-term effects of nicardipine, at rest and during exercise, in patients with coronary artery disease.
    Postgraduate medical journal, 1984, Volume: 60 Suppl 4

    Topics: Aged; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Coronary Disease; F

1984
Effects of nicardipine or nifedipine added to propranolol in patients with coronary artery disease.
    Postgraduate medical journal, 1984, Volume: 60 Suppl 4

    Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Coronary Disease; Drug Therapy, Combination;

1984
[Protective effect of nicardipine hydrochloride on the perfused ischemic canine myocardium].
    Kokyu to junkan. Respiration & circulation, 1983, Volume: 31, Issue:11

    Topics: Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Dogs; Hemodynamics; Myoca

1983
Assessment of regional left ventricular relaxation in patients with coronary artery disease: importance of geometric factors and changes in wall thickness.
    Circulation, 1984, Volume: 69, Issue:4

    Topics: Adult; Aged; Coronary Disease; Heart Ventricles; Humans; Middle Aged; Muscle Relaxation; Nicardipine

1984
Effects of nicardipine, a new dihydropyridine vasodilator, on coronary circulation and ischemia-induced conduction delay in dogs.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:6

    Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Dogs; Electrophysiology; Female; He

1982
Coronary vasomotion during dynamic exercise: influence of intravenous and intracoronary nicardipine.
    Journal of the American College of Cardiology, 1995, Volume: 26, Issue:3

    Topics: Aged; Analysis of Variance; Cardiac Catheterization; Coronary Angiography; Coronary Disease; Coronar

1995
[Effects on hemodynamics and myocardial metabolism of nicardipine and nitroglycerin during aortic cross clamp in dogs with experimentally produced coronary stenosis].
    Masui. The Japanese journal of anesthesiology, 1994, Volume: 43, Issue:3

    Topics: Animals; Aorta; Constriction; Coronary Circulation; Coronary Disease; Dogs; Hemodynamics; Lactates;

1994
Reversal of preexisting vasospasm in coronary artery conduits.
    The Annals of thoracic surgery, 2001, Volume: 72, Issue:2

    Topics: Arteries; Calcium Channel Blockers; Coronary Artery Bypass; Coronary Disease; Culture Techniques; Di

2001
The influence of nicardipine on left ventricular hemodynamics and compliance in patients with coronary heart disease.
    Journal of cardiovascular pharmacology, 1990, Volume: 16 Suppl 2

    Topics: Aged; Case-Control Studies; Coronary Disease; Female; Hemodynamics; Humans; Male; Middle Aged; Nicar

1990
[Effects of nicardipine on the functional state of the liver in patients with ischemic heart disease].
    Klinicheskaia meditsina, 1991, Volume: 69, Issue:10

    Topics: Adult; Coronary Disease; Humans; Liver; Liver Function Tests; Middle Aged; Nicardipine

1991
Protection against ischaemic ventricular fibrillation by blocking agents of myocardial cell calcium influx. Electrophysiological study in the pig in situ heart.
    Fundamental & clinical pharmacology, 1991, Volume: 5, Issue:7

    Topics: Animals; Calcium; Calcium Channel Blockers; Coronary Disease; Diltiazem; Electrophysiology; Myocardi

1991
[Bolus nicardipine in the hemodynamic assessment for heart transplantation of patients with severe failure of ischemic origin and high pulmonary resistance].
    Giornale italiano di cardiologia, 1991, Volume: 21, Issue:10

    Topics: Adult; Cardiac Catheterization; Coronary Angiography; Coronary Disease; Female; Heart Failure; Heart

1991
Nicardipine prevents calcium loading and "oxygen paradox" in anoxic single rat myocytes by a mechanism independent of calcium channel blockade.
    Circulation research, 1991, Volume: 69, Issue:6

    Topics: Animals; Calcium; Cell Survival; Coronary Disease; Dose-Response Relationship, Drug; Hypoxia; In Vit

1991
Left ventricular diastolic function in patients with left ventricular systolic dysfunction due to coronary artery disease and effect of nicardipine.
    The American journal of cardiology, 1991, Apr-15, Volume: 67, Issue:9

    Topics: Atrial Function, Right; Blood Pressure; Cardiac Output; Coronary Disease; Diastole; Female; Gated Bl

1991
[Effects of nicardipine in silent myocardial ischemia].
    Kardiologiia, 1991, Volume: 31, Issue:2

    Topics: Adult; Angina Pectoris; Coronary Disease; Drug Evaluation; Electrocardiography; Heart; Humans; Male;

1991
Kinetics and hemodynamic effects of intravenous nicardipine modified by previous propranolol oral treatment.
    Cardiovascular drugs and therapy, 1990, Volume: 4, Issue:6

    Topics: Administration, Oral; Adult; Catheterization, Swan-Ganz; Coronary Disease; Drug Interactions; Hemody

1990
Determination of the extent of ischemic damage and the effect of the calcium antagonist, verapamil following coronary artery ligation in the rat.
    Methods and findings in experimental and clinical pharmacology, 1990, Volume: 12, Issue:7

    Topics: Animals; Calcium; Constriction; Coronary Disease; Creatine Kinase; L-Lactate Dehydrogenase; Male; My

1990
Acute antianginal hemodynamic effects of nicardipine in coronary artery disease.
    American heart journal, 1990, Volume: 119, Issue:2 Pt 2

    Topics: Aged; Angina Pectoris; Cardiac Pacing, Artificial; Coronary Disease; Exercise; Hemodynamics; Humans;

1990
[Functional and metabolic effects of nicardipine on ischemic rat hearts with multidose potassium cardioplegia].
    [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai, 1990, Volume: 38, Issue:4

    Topics: Animals; Cardioplegic Solutions; Coronary Disease; Heart; Heart Arrest, Induced; In Vitro Techniques

1990
Effect of nicardipine on determinants of myocardial ischemia occurring during acute coronary occlusion produced by percutaneous transluminal coronary angioplasty.
    The American journal of cardiology, 1987, Aug-01, Volume: 60, Issue:4

    Topics: Aged; Angioplasty, Balloon; Collateral Circulation; Coronary Circulation; Coronary Disease; Electroc

1987
[Improvement of ischemic tolerance during percutaneous transluminal coronary angioplasty (PTCA) by nicardipine and trinitroglyceride (TNG)].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1989, Volume: 78, Issue:9

    Topics: Angioplasty, Balloon, Coronary; Coronary Disease; Electrocardiography; Hemodynamics; Humans; Lactate

1989
The efficacy of nicardipine and nitroprusside in preventing poststernotomy hypertension.
    Journal of cardiothoracic anesthesia, 1989, Volume: 3, Issue:6

    Topics: Blood Pressure; Cardiac Output; Coronary Artery Bypass; Coronary Disease; Heart Rate; Humans; Hypert

1989
[Changes in the platelet-vascular system of hemostasis in patients with ischemic heart disease and hypertension after the treatment].
    Kardiologiia, 1989, Volume: 29, Issue:10

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Blood Coagulation; Calcium Channel Blockers; Cor

1989
[New approach to the development of Ca antagonists].
    Nihon rinsho. Japanese journal of clinical medicine, 1989, Volume: 47, Issue:8

    Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Disease; Humans; Hypertension; Nic

1989
Nicardipine in systemic sclerosis.
    The Journal of rheumatology, 1989, Volume: 16, Issue:3

    Topics: Coronary Circulation; Coronary Disease; Humans; Nicardipine; Scleroderma, Systemic

1989
Effect of nicardipine on left ventricular function and on angina induced by atrial pacing in patients with coronary artery disease.
    International journal of cardiology, 1985, Volume: 9, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Cardiac Pacing,

1985
The clinical performance of nicardipine in elderly hypertensive patients with concomitant diseases.
    American heart journal, 1989, Volume: 117, Issue:1

    Topics: Aged; Arterial Occlusive Diseases; Blood Pressure; Coronary Disease; Diabetes Complications; Humans;

1989
Electrophysiologic evaluation of intravenous nicardipine in man.
    International journal of cardiology, 1989, Volume: 22, Issue:2

    Topics: Blood Pressure; Bundle of His; Cardiomyopathy, Hypertrophic; Coronary Disease; Electrocardiography;

1989
[Arterial hypertension, myocardial hypertrophy and disorders of cardiac rhythm induced by ligation of the left coronary artery in the rat].
    Archives des maladies du coeur et des vaisseaux, 1987, Volume: 80, Issue:6

    Topics: Animals; Cardiomegaly; Coronary Disease; Coronary Vessels; Hypertension; Ligation; Male; Nicardipine

1987
[Systemic and coronary hemodynamic effects of intravenous nicardipine at rest and in ischemia induced by rapid atrial stimulation].
    Archives des maladies du coeur et des vaisseaux, 1987, Volume: 80, Issue:10

    Topics: Adult; Angina Pectoris; Cardiac Pacing, Artificial; Coronary Circulation; Coronary Disease; Female;

1987
Systemic and coronary hemodynamics of labetalol in normotensive patients with ischemic heart disease.
    Cardiovascular drugs and therapy, 1988, Volume: 2, Issue:3

    Topics: Coronary Circulation; Coronary Disease; Diltiazem; Hemodynamics; Humans; Labetalol; Nicardipine

1988
Hemodynamic and cardiac metabolic changes during nicardipine-induced myocardial ischemia.
    Catheterization and cardiovascular diagnosis, 1988, Volume: 14, Issue:1

    Topics: Angina Pectoris; Coronary Disease; Electrocardiography; Exercise Test; Hemodynamics; Humans; Male; M

1988
Beneficial effects of intracoronary nicardipine on hypoxic myocardium.
    Japanese heart journal, 1987, Volume: 28, Issue:6

    Topics: Adenine Nucleotides; Animals; Coronary Disease; Coronary Vessels; Dogs; Energy Metabolism; Infusions

1987
Effects of the new dihydropyridine derivative 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid methyl 6-(5-phenyl-3-pyrazolyloxy)hexyl ester on the cardiohemodynamics and the energy metabolism of ischemic myocardium.
    Arzneimittel-Forschung, 1987, Volume: 37, Issue:12

    Topics: Animals; Blood Pressure; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Coronary Circulati

1987
Effects of nicardipine on exercise- and pacing-induced myocardial ischemia in angina pectoris.
    The American journal of cardiology, 1987, Sep-01, Volume: 60, Issue:7

    Topics: Angina Pectoris; Cardiac Catheterization; Cardiac Pacing, Artificial; Coronary Circulation; Coronary

1987
Pharmacokinetic, haemodynamic and radionuclide studies with nicardipine in coronary artery disease.
    European journal of clinical pharmacology, 1986, Volume: 29, Issue:6

    Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Cardiac Output; Coronary Disease; Heart Rate; Hemodyna

1986
Comparative effects of nicardipine, a new calcium antagonist, on size of myocardial infarction after coronary artery occlusion in dogs.
    Circulation, 1986, Volume: 74, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Coronary Circulation; Coronary Disease; Dogs; Female; Hemodynamics; M

1986
[Protective effect of nicardipine in an experimental model of transient myocardial ischemia in anesthetized dogs].
    Cardiologia (Rome, Italy), 1986, Volume: 31, Issue:1

    Topics: Animals; Coronary Disease; Dogs; Electrocardiography; Female; Hemodynamics; Lactates; Lactic Acid; M

1986
Impaired regional diastolic distensibility in coronary artery disease: relations with dynamic left ventricular compliance.
    American heart journal, 1986, Volume: 112, Issue:4

    Topics: Adult; Angina Pectoris; Coronary Circulation; Coronary Disease; Humans; Middle Aged; Myocardial Cont

1986
Acute hemodynamic effects of intravenous nicardipine in patients treated chronically with propranolol for coronary artery disease.
    The American journal of cardiology, 1987, Apr-01, Volume: 59, Issue:8

    Topics: Adult; Aged; Blood Pressure; Cardiac Output; Coronary Disease; Drug Therapy, Combination; Heart Rate

1987
Effects of nicardipine on left ventricular function and energetics in man.
    International journal of cardiology, 1986, Volume: 10, Issue:3

    Topics: Angina Pectoris; Calcium Channel Blockers; Cardiac Output; Coronary Circulation; Coronary Disease; H

1986
Myocardial ischemia during intravenous nicardipine administration.
    The American journal of cardiology, 1985, Mar-01, Volume: 55, Issue:6

    Topics: Aged; Coronary Disease; Hemodynamics; Humans; Male; Nicardipine; Nifedipine; Oxygen Consumption; Vas

1985
Immediate and long-term effects of nicardipine, at rest and during exercise, in patients with coronary artery disease.
    British journal of clinical pharmacology, 1985, Volume: 20 Suppl 1

    Topics: Aged; Calcium Channel Blockers; Coronary Disease; Female; Hemodynamics; Humans; Male; Middle Aged; N

1985
Effects of nicardipine on ischemic mechanical failure and tissue injury in isolated perfused rat heart.
    Japanese heart journal, 1985, Volume: 26, Issue:5

    Topics: Adenine Nucleotides; Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Creatine Kinas

1985