Page last updated: 2024-11-01

nicardipine and Coronary Artery Disease

nicardipine has been researched along with Coronary Artery Disease in 10 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Coronary Artery Disease: Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.

Research Excerpts

ExcerptRelevanceReference
"Nicardipine proved to be a safe and effective option in the management of complications such as no reflow in patients receiving therapies to restore blood flow following CAD."7.01Therapeutic and safety outcomes of intracoronary nicardipine in coronary artery disease patients: a systematic review. ( Ahmed, J; Asghar, MS; Hussain, HU; Imran, L; Islam, MS; Javed, SO; Rehan, ST; Salim, A; Sohail, A; Yasmin, F, 2023)
"Nicardipine proved to be a safe and effective option in the management of complications such as no reflow in patients receiving therapies to restore blood flow following CAD."3.01Therapeutic and safety outcomes of intracoronary nicardipine in coronary artery disease patients: a systematic review. ( Ahmed, J; Asghar, MS; Hussain, HU; Imran, L; Islam, MS; Javed, SO; Rehan, ST; Salim, A; Sohail, A; Yasmin, F, 2023)
"Angiographic progression of coronary atherosclerosis is frequently observed in clinical practice and is used as an end point in clinical trials; however, its prognostic significance is unclear."2.67Prognostic significance of progression of coronary atherosclerosis. ( Craven, TE; Lespérance, J; Waters, D, 1993)
"or placebo."2.67Retardation of development and progression of coronary atherosclerosis: a new indication for calcium antagonists? ( Alle, M; Cieslinski, G; Kaltenbach, M; Kober, G; Noack, H; Reifart, N; Roebruck, P; Schneider, W, 1990)
"Nicardipine was administered as a 200 μg IC bolus, after which repeat angiography was performed."1.51The Spontaneous Coronary Slow-Flow Phenomenon: Reversal by Intracoronary Nicardipine. ( Finley, JJ; Fischman, DL; McCarey, M; Mehta, HH; Morris, M; Ruggiero, N; Savage, MP; Walinsky, P, 2019)
"Nicardipine therapy was well tolerated without adverse hemodynamic or chronotropic effects."1.33Efficacy of intracoronary nicardipine in the treatment of no-reflow during percutaneous coronary intervention. ( Awar, M; Fischman, DL; Frankil, C; Huang, RI; Ogilby, JD; Patel, P; Savage, MP; Walinsky, P, 2006)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's3 (30.00)18.2507
2000's3 (30.00)29.6817
2010's1 (10.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Rehan, ST1
Imran, L1
Salim, A1
Javed, SO1
Sohail, A1
Hussain, HU1
Ahmed, J1
Yasmin, F1
Islam, MS1
Asghar, MS1
Jiang, Q1
Yang, Y1
Sun, H1
Tang, Y1
Lv, F1
Hu, S1
Mehta, HH1
Morris, M1
Fischman, DL2
Finley, JJ1
Ruggiero, N1
Walinsky, P2
McCarey, M1
Savage, MP2
Arora, S1
Alfayoumi, F1
Khawaja, AT1
Dua, A1
Srinivasan, V1
Gradman, AH1
Fischell, T1
Haller, S1
Ashraf, K1
Huang, RI1
Patel, P1
Ogilby, JD1
Awar, M1
Frankil, C1
Waters, D3
Craven, TE1
Lespérance, J3
Francetich, M1
Causey, D1
Théroux, P2
Chiang, YK1
Hudon, G2
Lemarbre, L2
Reitman, M1
Joyal, M2
Schneider, W1
Kober, G1
Roebruck, P1
Noack, H1
Alle, M1
Cieslinski, G1
Reifart, N1
Kaltenbach, M1
Freedman, D1
Kamm, B1
Dyrda, I1
Gosselin, G1

Reviews

1 review available for nicardipine and Coronary Artery Disease

ArticleYear
Therapeutic and safety outcomes of intracoronary nicardipine in coronary artery disease patients: a systematic review.
    Future cardiology, 2023, Volume: 19, Issue:3

    Topics: Adult; Angioplasty, Balloon, Coronary; Coronary Artery Disease; Coronary Circulation; Humans; Nicard

2023

Trials

6 trials available for nicardipine and Coronary Artery Disease

ArticleYear
Stable Hemodynamics within "No-Touch" Saphenous Vein Graft.
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2020, Apr-20, Volume: 26, Issue:2

    Topics: Aged; Beijing; Blood Flow Velocity; Coronary Artery Bypass, Off-Pump; Coronary Artery Disease; Femal

2020
Effect of intracoronary nicardipine on cardiac enzymes after elective percutaneous coronary intervention.
    Clinical cardiology, 2009, Volume: 32, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Biomarkers; Calcium Channel Blockers; Coronary Artery Disease; Creat

2009
Prognostic significance of progression of coronary atherosclerosis.
    Circulation, 1993, Volume: 87, Issue:4

    Topics: Coronary Angiography; Coronary Artery Disease; Female; Follow-Up Studies; Humans; Male; Middle Aged;

1993
A controlled clinical trial to assess the effect of a calcium channel blocker on the progression of coronary atherosclerosis.
    Circulation, 1990, Volume: 82, Issue:6

    Topics: Adult; Aged; Angiography; Calcium Channel Blockers; Cholesterol; Coronary Angiography; Coronary Arte

1990
Retardation of development and progression of coronary atherosclerosis: a new indication for calcium antagonists?
    European journal of clinical pharmacology, 1990, Volume: 39 Suppl 1

    Topics: Animals; Coronary Artery Bypass; Coronary Artery Disease; Diet, Atherogenic; Diltiazem; Female; Huma

1990
Design features of a controlled clinical trial to assess the effect of a calcium entry blocker upon the progression of coronary artery disease.
    Controlled clinical trials, 1987, Volume: 8, Issue:3

    Topics: Adult; Aged; Angiocardiography; Clinical Trials as Topic; Coronary Artery Disease; Coronary Disease;

1987

Other Studies

3 other studies available for nicardipine and Coronary Artery Disease

ArticleYear
The Spontaneous Coronary Slow-Flow Phenomenon: Reversal by Intracoronary Nicardipine.
    The Journal of invasive cardiology, 2019, Volume: 31, Issue:3

    Topics: Adult; Angina Pectoris; Cohort Studies; Coronary Angiography; Coronary Artery Disease; Coronary Circ

2019
Intragraft nicardipine prophylaxis to prevent no-reflow in triple-vessel saphenous vein graft intervention.
    The Journal of invasive cardiology, 2005, Volume: 17, Issue:6

    Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Coronary Artery Bypass; Coronary Artery Dis

2005
Efficacy of intracoronary nicardipine in the treatment of no-reflow during percutaneous coronary intervention.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2006, Volume: 68, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Coronary A

2006