nicardipine has been researched along with Colonic Diseases, Functional in 4 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
Colonic Diseases, Functional: Chronic or recurrent colonic disorders without an identifiable structural or biochemical explanation. The widely recognized IRRITABLE BOWEL SYNDROME falls into this category.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nicardipine was administered orally in standard (20 mg) and sustained-release (30 mg twice a day) formulations." | 2.67 | Effect of oral nicardipine on anorectal function in normal human volunteers and patients with irritable bowel syndrome. ( Edwards, CA; Prior, A; Rao, SS; Read, NW; Sun, WM, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sandle, GI | 1 |
| Butterfield, I | 1 |
| Higgs, NB | 1 |
| Warhurst, G | 1 |
| Maxton, DG | 1 |
| Whorwell, PJ | 2 |
| Sun, WM | 1 |
| Edwards, CA | 1 |
| Prior, A | 2 |
| Rao, SS | 1 |
| Read, NW | 1 |
| Harris, SR | 1 |
2 trials available for nicardipine and Colonic Diseases, Functional
| Article | Year |
|---|---|
Effect of intra-colonic nicardipine on colonic motility in irritable bowel syndrome.
Topics: Adult; Colon; Colonic Diseases, Functional; Female; Gastrointestinal Motility; Humans; Male; Middle | 1990 |
Effect of oral nicardipine on anorectal function in normal human volunteers and patients with irritable bowel syndrome.
Topics: Administration, Oral; Adult; Aged; Anal Canal; Colonic Diseases, Functional; Delayed-Action Preparat | 1990 |
2 other studies available for nicardipine and Colonic Diseases, Functional
| Article | Year |
|---|---|
Direct inhibitory effect of nicardipine on basolateral K+ channels in human colonic crypts.
Topics: Animals; Bucladesine; Calcium; Calcium Channel Blockers; Cell Membrane; Chlorides; Colon; Colonic Di | 1999 |
Reduction of colonic motility by intravenous nicardipine in irritable bowel syndrome.
Topics: Adult; Colon; Colonic Diseases, Functional; Female; Food; Gastrointestinal Motility; Humans; Male; M | 1987 |