Page last updated: 2024-11-01

nicardipine and Cognition Disorders

nicardipine has been researched along with Cognition Disorders in 3 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.

Research Excerpts

ExcerptRelevanceReference
"The lipid-soluble calcium channel-blocking drug nicardipine or matching placebo were randomly assigned to 26 patients with major depressive disorder receiving ECT."5.09Nicardipine improves the antidepressant action of ECT but does not improve cognition. ( Buzan, R; Cullum, CM; Dubovsky, SL; Kassner, C; Thomas, M, 2001)
"Nicardipine is a dihydropyridine-type Ca(2+) channel blocker (CCB) with strong antihypertensive activity and with a peculiar cerebrovascular profile."2.45Nicardipine use in cerebrovascular disease: a review of controlled clinical studies. ( Amenta, F; Lanari, A; Mignini, F; Silvestrelli, G; Tomassoni, D; Traini, E, 2009)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amenta, F1
Lanari, A1
Mignini, F1
Silvestrelli, G1
Traini, E1
Tomassoni, D1
Ikegaya, Y1
Nishiyama, N1
Matsuki, N1
Dubovsky, SL1
Buzan, R1
Thomas, M1
Kassner, C1
Cullum, CM1

Reviews

1 review available for nicardipine and Cognition Disorders

ArticleYear
Nicardipine use in cerebrovascular disease: a review of controlled clinical studies.
    Journal of the neurological sciences, 2009, Aug-15, Volume: 283, Issue:1-2

    Topics: Antihypertensive Agents; Calcium Channel Blockers; Cerebrovascular Disorders; Cognition; Cognition D

2009

Trials

1 trial available for nicardipine and Cognition Disorders

ArticleYear
Nicardipine improves the antidepressant action of ECT but does not improve cognition.
    The journal of ECT, 2001, Volume: 17, Issue:1

    Topics: Adult; Age Factors; Calcium Channel Blockers; Cognition Disorders; Depressive Disorder; Double-Blind

2001

Other Studies

1 other study available for nicardipine and Cognition Disorders

ArticleYear
L-type Ca(2+) channel blocker inhibits mossy fiber sprouting and cognitive deficits following pilocarpine seizures in immature mice.
    Neuroscience, 2000, Volume: 98, Issue:4

    Topics: Animals; Animals, Newborn; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Cogn

2000