Page last updated: 2024-11-01

nicardipine and Cirrhosis, Liver

nicardipine has been researched along with Cirrhosis, Liver in 4 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Research Excerpts

ExcerptRelevanceReference
"The present study was designed to compare the pharmacokinetic handling of a single oral dose of nicardipine in normal subjects and in patients with hepatic cirrhosis and to compare the sensitivity of the two groups to its hypotensive effect."1.28The effect of hepatic cirrhosis on the pharmacokinetics and blood pressure response to nicardipine. ( Conway, EL; Drummer, OH; Louis, WJ; McNeil, JJ; Razak, TA; Sewell, RB; Smallwood, RA, 1990)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
García-Pagán, JC1
Feu, F1
Luca, A1
Fernández, M1
Pizcueta, P1
Bosch, J1
Rodés, J1
Iwao, T2
Toyonaga, A2
Ikegami, M2
Oho, K2
Sumino, M2
Sakaki, M2
Shigemori, H1
Nakayama, M1
Sasaki, E1
Tanikawa, K1
Sugawara, H1
Takagi, K1
Ohkubo, K1
Inoue, R1
Razak, TA1
McNeil, JJ1
Sewell, RB1
Drummer, OH1
Smallwood, RA1
Conway, EL1
Louis, WJ1

Trials

2 trials available for nicardipine and Cirrhosis, Liver

ArticleYear
Nicardipine increases hepatic blood flow and the hepatic clearance of indocyanine green in patients with cirrhosis.
    Journal of hepatology, 1994, Volume: 20, Issue:6

    Topics: Aged; Female; Hemodynamics; Humans; Hypertension, Portal; Indocyanine Green; Liver Circulation; Live

1994
Effects of vasopressin and nicardipine on hemodynamics and liver function in patients with cirrhosis: comparison with vasopressin alone.
    Journal of hepatology, 1993, Volume: 19, Issue:3

    Topics: Aged; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension, Portal; Liver; Liver Ci

1993

Other Studies

2 other studies available for nicardipine and Cirrhosis, Liver

ArticleYear
Nicardipine infusion improved hepatic function but failed to reduce hepatic venous pressure gradient in patients with cirrhosis.
    The American journal of gastroenterology, 1992, Volume: 87, Issue:3

    Topics: Adult; Aged; Female; Hemodynamics; Humans; Hypertension, Portal; Infusions, Intravenous; Liver; Live

1992
The effect of hepatic cirrhosis on the pharmacokinetics and blood pressure response to nicardipine.
    Clinical pharmacology and therapeutics, 1990, Volume: 47, Issue:4

    Topics: Adult; Aged; Antipyrine; Biotransformation; Blood Pressure; Female; Half-Life; Humans; Liver; Liver

1990