nicardipine has been researched along with Cardiovascular Diseases in 7 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nicardipine is an antagonist of calcium influx through the slow channel of the cell membrane and has been shown to be an effective and relatively well-tolerated treatment for stable effort angina and rest angina due to coronary artery spasm, and mild to moderate hypertension." | 8.77 | Nicardipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in the treatment of angina pectoris, hypertension and related cardiovascular disorders. ( Clissold, SP; Sorkin, EM, 1987) |
| "Nicardipine is an antagonist of calcium influx through the slow channel of the cell membrane and has been shown to be an effective and relatively well-tolerated treatment for stable effort angina and rest angina due to coronary artery spasm, and mild to moderate hypertension." | 4.77 | Nicardipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in the treatment of angina pectoris, hypertension and related cardiovascular disorders. ( Clissold, SP; Sorkin, EM, 1987) |
| " With nicardipine poisoning, survival was also prolonged in the ILE group (71." | 3.81 | The effects of intravenous lipid emulsion on prolongation of survival in a rat model of calcium channel blocker toxicity. ( Jeong, JH; Kang, C; Kang, TS; Kim, DH; Kim, RB; Kim, SC; Lee, DH; Lee, SH; Shin, IW, 2015) |
| "Cardiovascular diseases are a leading cause of hospitalizations and death in the United States and elsewhere in the world." | 2.46 | Cardiovascular pharmacology: an update. ( Fox, CJ; Kaye, AD; Liu, H; Zhang, S, 2010) |
| "Nicardipine has been shown to be effective in the treatment of mild to moderate hypertension both as monotherapy and in combination with other antihypertensive agents." | 2.37 | Intravenous nicardipine: cardiovascular effects and clinical relevance. ( Pepine, CJ, 1988) |
| "Bepridil is an effective antianginal drug, but, because of its proarrhythmic potential, it should probably not be used as a first-line agent." | 2.37 | Nicardipine, nitrendipine, and bepridil: new calcium antagonists for cardiovascular disorders. ( Hasegawa, GR, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kang, C | 1 |
| Kim, DH | 1 |
| Kim, SC | 1 |
| Lee, SH | 1 |
| Jeong, JH | 1 |
| Kang, TS | 1 |
| Shin, IW | 1 |
| Kim, RB | 1 |
| Lee, DH | 1 |
| Liu, H | 1 |
| Fox, CJ | 1 |
| Zhang, S | 1 |
| Kaye, AD | 1 |
| Kuramoto, K | 1 |
| Poelaert, J | 1 |
| Roosens, C | 1 |
| Pepine, CJ | 1 |
| Hasegawa, GR | 1 |
| Sorkin, EM | 1 |
| Clissold, SP | 1 |
5 reviews available for nicardipine and Cardiovascular Diseases
| Article | Year |
|---|---|
Cardiovascular pharmacology: an update.
Topics: Animals; Cardiovascular Agents; Cardiovascular Diseases; Diastole; Heart Failure; Humans; Hydrazones | 2010 |
Perioperative use of dihydropyridine calcium channel blockers.
Topics: Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Dihydropyridines; Humans; Intraop | 2000 |
Intravenous nicardipine: cardiovascular effects and clinical relevance.
Topics: Animals; Cardiovascular Diseases; Hemodynamics; Humans; Nicardipine | 1988 |
Nicardipine, nitrendipine, and bepridil: new calcium antagonists for cardiovascular disorders.
Topics: Bepridil; Calcium Channel Blockers; Cardiovascular Diseases; Humans; Nicardipine; Nitrendipine; Pyrr | 1988 |
Nicardipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in the treatment of angina pectoris, hypertension and related cardiovascular disorders.
Topics: Angina Pectoris; Cardiovascular Diseases; Humans; Hypertension; Kinetics; Nicardipine | 1987 |
1 trial available for nicardipine and Cardiovascular Diseases
| Article | Year |
|---|---|
Treatment of elderly hypertensives in Japan: National Intervention Cooperative Study in Elderly Hypertensives. The National Intervention Cooperative Study Group.
Topics: Aged; Cardiovascular Diseases; Cerebrovascular Disorders; Double-Blind Method; Female; Humans; Hyper | 1994 |
1 other study available for nicardipine and Cardiovascular Diseases
| Article | Year |
|---|---|
The effects of intravenous lipid emulsion on prolongation of survival in a rat model of calcium channel blocker toxicity.
Topics: Animals; Antidotes; Arterial Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; | 2015 |