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nicardipine and Cardiac Output, Low

nicardipine has been researched along with Cardiac Output, Low in 4 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Cardiac Output, Low: A state of subnormal or depressed cardiac output at rest or during stress. It is a characteristic of CARDIOVASCULAR DISEASES, including congenital, valvular, rheumatic, hypertensive, coronary, and cardiomyopathic. The serious form of low cardiac output is characterized by marked reduction in STROKE VOLUME, and systemic vasoconstriction resulting in cold, pale, and sometimes cyanotic extremities.

Research Excerpts

ExcerptRelevanceReference
"Nicardipine is a potent arteriolar vasodilator with a negligible negative inotropic effect."2.68Determining the optimum dose for the intravenous administration of nicardipine in the treatment of acute heart failure--a multicenter study. The Nicardipine Heart Failure Study Group. ( Hirota, Y; Hori, R; Kawai, C; Kawamura, K; Kinoshita, M; Kumada, T; Kusukawa, R; Ogawa, H; Okumura, K, 1997)
"Nicardipine hydrochloride is a newer agent that has undergone extensive evaluation in recent years."2.38Clinical pharmacology, pharmacokinetics, and hemodynamic effects of nicardipine. ( Josephson, MA; Singh, BN, 1990)
" The purpose of the present study was to investigate whether the use of nicardipine (Nc) and phentolamine (Ph) in combination with NE could ameliorate the adverse vasoconstrictive action of NE."1.30Hemodynamic effects of nicardipine and phentolamine in combination with norepinephrine in a canine low-output-state model. ( Hashiyada, H; Kugimiya, T; Miyagawa, N; Shibata, R; Takagi, M; Yamada, T; Yamauchi, H, 1997)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hirota, Y1
Kawai, C1
Hori, R1
Okumura, K1
Kinoshita, M1
Kumada, T1
Ogawa, H1
Kawamura, K1
Kusukawa, R1
Shibata, R1
Takagi, M1
Kugimiya, T1
Yamauchi, H1
Yamada, T1
Hashiyada, H1
Miyagawa, N1
Singh, BN1
Josephson, MA1
Fifer, MA1
Aroney, CN1
Semigran, MJ1
Herrmann, HC1
Dec, GW1
Boucher, CA1

Reviews

2 reviews available for nicardipine and Cardiac Output, Low

ArticleYear
Clinical pharmacology, pharmacokinetics, and hemodynamic effects of nicardipine.
    American heart journal, 1990, Volume: 119, Issue:2 Pt 2

    Topics: Adrenergic beta-Antagonists; Animals; Cardiac Output, Low; Chemical Phenomena; Chemistry; Electrophy

1990
Techniques for assessing inotropic effects of drugs in patients with heart failure: application to the evaluation of nicardipine.
    American heart journal, 1990, Volume: 119, Issue:2 Pt 2

    Topics: Aged; Blood Pressure; Blood Volume; Cardiac Output, Low; Female; Heart Function Tests; Hemodynamics;

1990

Trials

1 trial available for nicardipine and Cardiac Output, Low

ArticleYear
Determining the optimum dose for the intravenous administration of nicardipine in the treatment of acute heart failure--a multicenter study. The Nicardipine Heart Failure Study Group.
    Japanese circulation journal, 1997, Volume: 61, Issue:5

    Topics: Acute Disease; Aged; Calcium Channel Blockers; Cardiac Output, Low; Dose-Response Relationship, Drug

1997

Other Studies

1 other study available for nicardipine and Cardiac Output, Low

ArticleYear
Hemodynamic effects of nicardipine and phentolamine in combination with norepinephrine in a canine low-output-state model.
    Japanese heart journal, 1997, Volume: 38, Issue:5

    Topics: Animals; Cardiac Output, Low; Dogs; Drug Therapy, Combination; Female; Hemodynamics; Male; Myocardia

1997