nicardipine has been researched along with Cancer of Lung in 3 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Enhancements of cytotoxic effects of adriamycin (ADM) and vincristine (VCR) on PC-6 (lung cancer cell line) and Hattori (breast cancer cell line) were investigated by concomitant use of a calmodulin inhibitor: nicardipine, antiplatelet agents: oxyfedrine and trimethazidine and an antihypertensive agent: trichlormethiazide." | 3.67 | [Enhanced cytotoxic effect of Adriamycin and vincristine against PC-6 (human lung cancer cell line) and Hattori (human breast cancer cell line)]. ( Inoue, K; Mitsui, I; Mukaiyama, T; Ogawa, M; Terashima, M, 1985) |
| "Inoperable lung adenocarcinoma is currently treated with platinum-based chemotherapy." | 1.42 | Cholesterol reduces the sensitivity to platinum-based chemotherapy via upregulating ABCG2 in lung adenocarcinoma. ( Fan, Y; He, Z; Si, R; Tang, H; Wang, L; Wang, Q; Wu, Y; Xia, S; Zhu, H, 2015) |
| "Nifedipine was included as the standard or reference compound." | 1.28 | In vivo characterization of combination antitumor chemotherapy with calcium channel blockers and cis-diamminedichloroplatinum(II). ( Honn, KV; Nelson, KK; Onoda, JM; Taylor, JD, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, Y | 1 |
| Si, R | 1 |
| Tang, H | 1 |
| He, Z | 2 |
| Zhu, H | 1 |
| Wang, L | 1 |
| Fan, Y | 1 |
| Xia, S | 1 |
| Wang, Q | 1 |
| Onoda, JM | 1 |
| Nelson, KK | 1 |
| Taylor, JD | 1 |
| Honn, KV | 1 |
| Terashima, M | 1 |
| Inoue, K | 1 |
| Mukaiyama, T | 1 |
| Mitsui, I | 1 |
| Ogawa, M | 1 |
3 other studies available for nicardipine and Cancer of Lung
| Article | Year |
|---|---|
Cholesterol reduces the sensitivity to platinum-based chemotherapy via upregulating ABCG2 in lung adenocarcinoma.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Aged; Antineoplastic Agents; Antineoplastic Combined Chemoth | 2015 |
In vivo characterization of combination antitumor chemotherapy with calcium channel blockers and cis-diamminedichloroplatinum(II).
Topics: Animals; Calcium Channel Blockers; Cisplatin; Diltiazem; Drug Evaluation, Preclinical; Drug Resistan | 1989 |
[Enhanced cytotoxic effect of Adriamycin and vincristine against PC-6 (human lung cancer cell line) and Hattori (human breast cancer cell line)].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Small Cell; Cell Line; | 1985 |