nicardipine has been researched along with Brain Infarction in 4 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
Brain Infarction: Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Outcome of patients with aneurysmal subarachnoid hemorrhage (SAH) has improved over the last decades." | 2.49 | SAHIT Investigators--on the outcome of some subarachnoid hemorrhage clinical trials. ( Cusimano, MD; Etminan, N; Hanggi, D; Hasan, D; Ilodigwe, D; Jaja, B; Lantigua, H; Le Roux, P; Lo, B; Louffat-Olivares, A; Macdonald, RL; Mayer, S; Molyneux, A; Quinn, A; Schenk, T; Schweizer, TA; Singh, J; Spears, J; Todd, M; Torner, J; Vergouwen, MD; Wong, GK, 2013) |
| "In a rat model of transient cerebral ischemia and reperfusion, we evaluated the effect of the calcium antagonist, nicardipine, on intracranial pressure (ICP)." | 1.35 | Intravenous infusion of calcium antagonist, nicardipine, does not increase intracranial pressure: evaluation in a rat model of transient cerebral ischemia and reperfusion. ( Harada, T; Kano, T; Katayama, Y; Matsuzaki, T; Nakamura, S, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Macdonald, RL | 1 |
| Jaja, B | 1 |
| Cusimano, MD | 1 |
| Etminan, N | 1 |
| Hanggi, D | 1 |
| Hasan, D | 1 |
| Ilodigwe, D | 1 |
| Lantigua, H | 1 |
| Le Roux, P | 1 |
| Lo, B | 1 |
| Louffat-Olivares, A | 1 |
| Mayer, S | 1 |
| Molyneux, A | 1 |
| Quinn, A | 1 |
| Schweizer, TA | 1 |
| Schenk, T | 1 |
| Spears, J | 1 |
| Todd, M | 1 |
| Torner, J | 1 |
| Vergouwen, MD | 1 |
| Wong, GK | 1 |
| Singh, J | 1 |
| Kurowski, D | 1 |
| Mullen, MT | 1 |
| Messé, SR | 1 |
| Barth, M | 1 |
| Pena, P | 1 |
| Seiz, M | 1 |
| Thomé, C | 1 |
| Muench, E | 1 |
| Weidauer, S | 1 |
| Hattingen, E | 1 |
| Kasuya, H | 1 |
| Schmiedek, P | 1 |
| Matsuzaki, T | 1 |
| Kano, T | 1 |
| Katayama, Y | 1 |
| Nakamura, S | 1 |
| Harada, T | 1 |
1 review available for nicardipine and Brain Infarction
| Article | Year |
|---|---|
SAHIT Investigators--on the outcome of some subarachnoid hemorrhage clinical trials.
Topics: Antioxidants; Brain Infarction; Calcium Channel Blockers; Critical Care; Dioxanes; Drug Therapy, Com | 2013 |
1 trial available for nicardipine and Brain Infarction
| Article | Year |
|---|---|
Feasibility of intraventricular nicardipine prolonged release implants in patients following aneurysmal subarachnoid haemorrhage.
Topics: Adult; Aged; Angiography, Digital Subtraction; Brain Infarction; Cerebral Ventricles; Delayed-Action | 2011 |
2 other studies available for nicardipine and Brain Infarction
| Article | Year |
|---|---|
Pearls & Oy-sters: Iatrogenic relative hypotension leading to diffuse internal borderzone infarctions and coma.
Topics: Adult; Antihypertensive Agents; Brain Infarction; Coma; Diffusion Magnetic Resonance Imaging; Fatal | 2016 |
Intravenous infusion of calcium antagonist, nicardipine, does not increase intracranial pressure: evaluation in a rat model of transient cerebral ischemia and reperfusion.
Topics: Analysis of Variance; Animals; Blood Pressure; Brain Infarction; Calcium Channel Blockers; Disease M | 2008 |