nicardipine has been researched along with Bradycardia in 10 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We compared the efficacy of the combination of enalaprilat/labetalol with that of enalaprilat/nicardipine to prevent emergence postcraniotomy hypertension." | 9.09 | A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery. ( Broad, C; Ferri, E; Kross, RA; Leung, D; Melendez, JA; Pratila, M; Veronesi, M, 2000) |
| "In patients with hemorrhagic stroke, nicardipine appeared to have similar efficacy as clevidipine in SBP reduction, with a more likely reduction of rebound hypertension and drug cost." | 8.12 | Comparison of Clevidipine and Nicardipine for Acute Blood Pressure Reduction in Hemorrhagic Stroke. ( Breslin, J; Hanify, J; Heierman, T; Larizadeh, K; Phipps, W; Saldana, S; Sanchez, M, 2022) |
| "To assess the safety and efficacy of continuous infusion (CIV)-labetalol compared to -nicardipine in controlling blood pressure (BP) in the acute stroke setting." | 8.02 | Blood Pressure Control in Acute Stroke: Labetalol or Nicardipine? ( El-Ghoroury, H; Hecht, JP; Sudekum, DM, 2021) |
| "Nicardipine is a dihydropyridine calcium-channel blocker that is frequently used in the acute treatment of hypertension in the emergency department (ED)." | 7.83 | Bradycardia caused by intravenous nicardipine in an elderly patient with acute ischemic infarct. ( Abboud, ME; Frasure, SE, 2016) |
| "Nicardipine-induced bradycardia has been reported in experimental animals but not in clinical patients." | 7.71 | Profound sinus bradycardia after intravenous nicardipine. ( Ando, H; Arima, H; Katsuya, H; Morishima, T; Sobue, K; Tanaka, S, 2002) |
| "We compared the efficacy of the combination of enalaprilat/labetalol with that of enalaprilat/nicardipine to prevent emergence postcraniotomy hypertension." | 5.09 | A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery. ( Broad, C; Ferri, E; Kross, RA; Leung, D; Melendez, JA; Pratila, M; Veronesi, M, 2000) |
| "In patients with hemorrhagic stroke, nicardipine appeared to have similar efficacy as clevidipine in SBP reduction, with a more likely reduction of rebound hypertension and drug cost." | 4.12 | Comparison of Clevidipine and Nicardipine for Acute Blood Pressure Reduction in Hemorrhagic Stroke. ( Breslin, J; Hanify, J; Heierman, T; Larizadeh, K; Phipps, W; Saldana, S; Sanchez, M, 2022) |
| "To assess the safety and efficacy of continuous infusion (CIV)-labetalol compared to -nicardipine in controlling blood pressure (BP) in the acute stroke setting." | 4.02 | Blood Pressure Control in Acute Stroke: Labetalol or Nicardipine? ( El-Ghoroury, H; Hecht, JP; Sudekum, DM, 2021) |
| "Nicardipine is a dihydropyridine calcium-channel blocker that is frequently used in the acute treatment of hypertension in the emergency department (ED)." | 3.83 | Bradycardia caused by intravenous nicardipine in an elderly patient with acute ischemic infarct. ( Abboud, ME; Frasure, SE, 2016) |
| "We encountered a 91-year-old woman with atrial fibrillation complicating bradycardia while she was receiving therapy with an L/N-type calcium channel blocker, cilnidipine, for hypertension, which is an unusual observation for the dihydropyridine class of calcium channel blockers." | 3.73 | Comparison of the direct negative dromotropic effect of a new calcium channel blocker, cilnidipine, with that of nicardipine. ( Ando, K; Hashimoto, K; Nakamura, Y; Satoh, Y; Sugiyama, A; Takahara, A, 2005) |
| " This study was designed to investigate the acute effects of local application of a SMF to neck or pelvic region under pharmacologically modulated BP; norepinephrine (NE)-induced hypertension as well as an L-type voltage-gated Ca(2+) channel blocker, nicardipine (NIC)-induced hypotension in conscious rabbits." | 3.73 | Effects of neck exposure to 5.5 mT static magnetic field on pharmacologically modulated blood pressure in conscious rabbits. ( Ohkubo, C; Okano, H, 2005) |
| "Nicardipine-induced bradycardia has been reported in experimental animals but not in clinical patients." | 3.71 | Profound sinus bradycardia after intravenous nicardipine. ( Ando, H; Arima, H; Katsuya, H; Morishima, T; Sobue, K; Tanaka, S, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 4 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saldana, S | 1 |
| Breslin, J | 1 |
| Hanify, J | 1 |
| Heierman, T | 1 |
| Larizadeh, K | 1 |
| Sanchez, M | 1 |
| Phipps, W | 1 |
| Lee, S | 1 |
| Ahn, YN | 1 |
| Lee, J | 1 |
| Kwon, S | 1 |
| Kang, HY | 1 |
| Ibarra, F | 1 |
| Holzmann, S | 1 |
| Shah, S | 1 |
| Fountain, C | 1 |
| Saleh, S | 1 |
| Kapoor, V | 1 |
| Dang, T | 1 |
| El-Ghoroury, H | 1 |
| Sudekum, DM | 1 |
| Hecht, JP | 1 |
| Abboud, ME | 1 |
| Frasure, SE | 1 |
| White, PF | 1 |
| Perdue, L | 1 |
| Downing, M | 1 |
| Thornton, L | 1 |
| Sugiyama, A | 1 |
| Satoh, Y | 1 |
| Takahara, A | 1 |
| Ando, K | 1 |
| Nakamura, Y | 1 |
| Hashimoto, K | 1 |
| Okano, H | 1 |
| Ohkubo, C | 1 |
| Kross, RA | 1 |
| Ferri, E | 1 |
| Leung, D | 1 |
| Pratila, M | 1 |
| Broad, C | 1 |
| Veronesi, M | 1 |
| Melendez, JA | 1 |
| Arima, H | 1 |
| Sobue, K | 1 |
| Tanaka, S | 1 |
| Morishima, T | 1 |
| Ando, H | 1 |
| Katsuya, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficiency of Intravenous Lidocaine to Reduce Coughing and the Hemodynamic Changes Associated to Tracheal Extubation[NCT03731429] | Phase 4 | 144 participants (Anticipated) | Interventional | 2019-04-05 | Recruiting | ||
| Nicardipine Versus Esmolol for Management of Emergence Hypertension After Craniotomy[NCT01951950] | Phase 1 | 40 participants (Actual) | Interventional | 2013-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT01951950)
Timeframe: 1 hour postoperatively
| Intervention | participants (Number) |
|---|---|
| Nicardipine | 1 |
| Esmolol | 11 |
2 trials available for nicardipine and Bradycardia
8 other studies available for nicardipine and Bradycardia
| Article | Year |
|---|---|
Comparison of Clevidipine and Nicardipine for Acute Blood Pressure Reduction in Hemorrhagic Stroke.
Topics: Acute Kidney Injury; Adult; Antihypertensive Agents; Blood Pressure; Bradycardia; Hematoma; Hemorrha | 2022 |
Utility of nicardipine in the management of hypertensive crises in adults with reduced ejection fractions.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Bradycardia; Heart Failure; Humans; Hypertension; Hy | 2024 |
Blood Pressure Control in Acute Stroke: Labetalol or Nicardipine?
Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pre | 2021 |
Bradycardia caused by intravenous nicardipine in an elderly patient with acute ischemic infarct.
Topics: Aged; Antihypertensive Agents; Bradycardia; Brain Ischemia; Calcium Channel Blockers; Humans; Hypert | 2016 |
Use of a bolus injection of nicardipine to prevent severe electroconvulsive therapy-induced bradycardia.
Topics: Bradycardia; Calcium Channel Blockers; Electroconvulsive Therapy; Humans; Injections, Intravenous; M | 2005 |
Comparison of the direct negative dromotropic effect of a new calcium channel blocker, cilnidipine, with that of nicardipine.
Topics: Aged; Analysis of Variance; Animals; Atrial Fibrillation; Bradycardia; Calcium Channel Blockers; Dih | 2005 |
Effects of neck exposure to 5.5 mT static magnetic field on pharmacologically modulated blood pressure in conscious rabbits.
Topics: Animals; Baroreflex; Blood Pressure; Bradycardia; Calcium Channel Blockers; Carotid Sinus; Conscious | 2005 |
Profound sinus bradycardia after intravenous nicardipine.
Topics: Aged; Arrhythmia, Sinus; Bradycardia; Calcium Channel Blockers; Electrocardiography; Esophageal Neop | 2002 |