nicardipine has been researched along with Body Weight in 13 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a double-blind controlled trial 22 patients with mild or moderate essential hypertension were treated with nicardipine 30 mg t." | 9.06 | Comparison of nicardipine and propranolol in the treatment of mild and moderate hypertension. ( Karppinen, K; Naukkarinen, VA; Sarna, S, 1987) |
| "Thirty-nine patients with mild to moderate essential hypertension participated in a parallel, single-blind study comparing 6 weeks' treatment of nicardipine hydrochloride (90 mg/day) with nifedipine (40 mg/day)." | 9.06 | Comparison of the efficacy of nicardipine, a new calcium channel blocker, with nifedipine in the treatment of mild to moderate essential hypertension. ( Armstrong, C; Blackwood, R; Garnham, J, 1987) |
| "Isradipine is an effective, orally administered agent for control of hypertension in children." | 7.70 | Initial experience with isradipine for the treatment of hypertension in children. ( Groshong, T; Strauser, LM; Tobias, JD, 2000) |
| "In a double-blind controlled trial 22 patients with mild or moderate essential hypertension were treated with nicardipine 30 mg t." | 5.06 | Comparison of nicardipine and propranolol in the treatment of mild and moderate hypertension. ( Karppinen, K; Naukkarinen, VA; Sarna, S, 1987) |
| "Thirty-nine patients with mild to moderate essential hypertension participated in a parallel, single-blind study comparing 6 weeks' treatment of nicardipine hydrochloride (90 mg/day) with nifedipine (40 mg/day)." | 5.06 | Comparison of the efficacy of nicardipine, a new calcium channel blocker, with nifedipine in the treatment of mild to moderate essential hypertension. ( Armstrong, C; Blackwood, R; Garnham, J, 1987) |
| "Isradipine is an effective, orally administered agent for control of hypertension in children." | 3.70 | Initial experience with isradipine for the treatment of hypertension in children. ( Groshong, T; Strauser, LM; Tobias, JD, 2000) |
| "The effect of nicardipine on experimental hyperlipemia induced by a 1% cholesterol diet in spontaneously hypertensive rats (SHR) was investigated by the change of hemodynamics and the determination of lipid contents of the serum, liver, heart and aorta." | 3.67 | [Effect of nicardipine on cholesterol-fed S.H.R]. ( Kawashima, I; Nakayama, S; Ohba, T; Sakamoto, K; Tonooka, M; Yasuhara, H, 1985) |
| "Treatment with nicardipine (20 mg/kg/day, s." | 1.31 | Antioxidant enzyme activities and total nitrite/nitrate levels in the collar model. Effect of nicardipine. ( Kerry, Z; Onat, T; Sözmen, EY; Ustünes, L; Uysal, F; Yasa, M; Yetik, G, 2000) |
| "In the drug-untreated group, recurrence of stroke was repeated, deterioration and amelioration of neurological deficits (ND) were repeated, and histological examination and measurement of regional blood flow (rBF) using nonradioactive colored microspheres performed at the end of treatment revealed severe damages and significantly decreased rBF in brain and kidney, respectively." | 1.30 | Therapeutic effects of a calcium antagonist, lacidipine, on stroke-prone spontaneously hypertensive rats with cerebrovascular lesions. ( Funato, H; Uemura, A; Watanabe, M, 1999) |
| "Nicardipine has been shown to have an anti-atherogenic effect in rabbits given a 2% cholesterol diet." | 1.29 | Effects of nicardipine on lipid peroxidation in rabbits given 2% cholesterol diet. ( Hashim, S; Ismail, NM; Jaarin, K; Vasudevan, SK, 1995) |
| " A clear species difference in LD50 values was found in acute toxicity of PP-1466, and rabbits were the most sensitive between animal species used, then dogs, mice and rats in order." | 1.27 | Acute and subacute toxicity of 2,6-dimethyl-3,5-dimethoxycarbonyl-4-(o-difluoromethoxyphenyl)-1 ,4-dihydropyridine (PP-1466). ( Aikawa, K; Fujikura, M; Gomi, T; Hirao, A; Kobayashi, M; Okumura, M; Ozeki, M; Tateishi, T; Yamamoto, H; Yumoto, S, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (38.46) | 18.7374 |
| 1990's | 6 (46.15) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takenaka, T | 1 |
| Suzuki, H | 1 |
| Ikenaga, H | 1 |
| Itaya, Y | 1 |
| Yamakawa, H | 1 |
| Sakamaki, Y | 1 |
| Saruta, T | 1 |
| Ueda, M | 1 |
| Masui, M | 1 |
| Kawakami, M | 1 |
| Matsunaga, K | 1 |
| Gemba, T | 1 |
| Ninomiya, M | 1 |
| Nakano, A | 1 |
| Torii, M | 1 |
| Adachi, I | 1 |
| Ito, H | 1 |
| Ismail, NM | 1 |
| Jaarin, K | 1 |
| Vasudevan, SK | 1 |
| Hashim, S | 1 |
| Kerry, Z | 2 |
| Yasa, M | 2 |
| Akpinar, R | 1 |
| Sevin, G | 1 |
| Yetik, G | 2 |
| Tosun, M | 1 |
| Ozdemir, N | 1 |
| Erhan, Y | 1 |
| Ustünes, L | 2 |
| Ozer, A | 1 |
| Funato, H | 1 |
| Watanabe, M | 1 |
| Uemura, A | 1 |
| Strauser, LM | 1 |
| Groshong, T | 1 |
| Tobias, JD | 1 |
| Sözmen, EY | 1 |
| Uysal, F | 1 |
| Onat, T | 1 |
| Kamata, K | 1 |
| Inoue, K | 1 |
| Kasuya, Y | 1 |
| Morimoto, S | 1 |
| Ohyama, T | 1 |
| Hisaki, K | 1 |
| Matsumura, Y | 1 |
| Naukkarinen, VA | 1 |
| Karppinen, K | 1 |
| Sarna, S | 1 |
| Armstrong, C | 1 |
| Garnham, J | 1 |
| Blackwood, R | 1 |
| Gomi, T | 1 |
| Yamamoto, H | 1 |
| Ozeki, M | 1 |
| Fujikura, M | 1 |
| Hirao, A | 1 |
| Kobayashi, M | 1 |
| Tateishi, T | 1 |
| Yumoto, S | 1 |
| Okumura, M | 1 |
| Aikawa, K | 1 |
| Ohba, T | 1 |
| Tonooka, M | 1 |
| Kawashima, I | 1 |
| Nakayama, S | 1 |
| Yasuhara, H | 1 |
| Sakamoto, K | 1 |
2 trials available for nicardipine and Body Weight
| Article | Year |
|---|---|
Comparison of nicardipine and propranolol in the treatment of mild and moderate hypertension.
Topics: Adult; Blood Pressure; Body Weight; Cholesterol; Clinical Trials as Topic; Double-Blind Method; Huma | 1987 |
Comparison of the efficacy of nicardipine, a new calcium channel blocker, with nifedipine in the treatment of mild to moderate essential hypertension.
Topics: Adult; Aged; Blood Pressure; Body Weight; Female; Heart Rate; Humans; Hypertension; Male; Middle Age | 1987 |
11 other studies available for nicardipine and Body Weight
| Article | Year |
|---|---|
Effects of a calcium channel blocker, nicardipine, on pressure-natriuresis in Dahl salt-sensitive rats.
Topics: Animals; Blood Pressure; Body Weight; Diet, Sodium-Restricted; Glomerular Filtration Rate; Homeostas | 1994 |
Pharmacological studies on a new dihydrothienopyridine calcium antagonist. 4th communication: prophylactic and therapeutic effects of S-(+)-methyl-4,7-dihydro-3-isobutyl-6-methyl-4-(3-nitrophenyl)thieno[2, 3- b]pyridine-5-carboxylate in stroke-prone spont
Topics: Animals; Behavior, Animal; Blood Pressure; Body Weight; Brain; Calcium Channel Blockers; Cerebrovasc | 1993 |
Effects of nicardipine on lipid peroxidation in rabbits given 2% cholesterol diet.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Body Weight; Cholesterol; Cholesterol, Dietary; Injections | 1995 |
Effects of nicardipine on collar-induced intimal thickening and vascular reactivity in the rabbit.
Topics: Acetylcholine; Animals; Body Weight; Calcium Channel Blockers; Carotid Arteries; Carotid Artery Dise | 1999 |
Therapeutic effects of a calcium antagonist, lacidipine, on stroke-prone spontaneously hypertensive rats with cerebrovascular lesions.
Topics: Animals; Blood Pressure; Body Weight; Brain; Calcium Channel Blockers; Cerebellum; Cerebrovascular D | 1999 |
Initial experience with isradipine for the treatment of hypertension in children.
Topics: Administration, Oral; Antihypertensive Agents; Blood Pressure; Body Weight; Calcium Channel Blockers | 2000 |
Antioxidant enzyme activities and total nitrite/nitrate levels in the collar model. Effect of nicardipine.
Topics: Animals; Antioxidants; Body Weight; Calcium Channel Blockers; Carotid Arteries; Catalase; Cholestero | 2000 |
Changes in muscarinic responsiveness, muscarinic receptor density and Ca2+ mobilization of the urinary bladder in streptozotocin-induced diabetic rats.
Topics: Acetylcholine; Animals; Blood Glucose; Body Weight; Calcium; Calcium Channels; Diabetes Mellitus, Ex | 1992 |
Effects of CV-4093, a new dihydropyridine calcium channel blocker, on renal hemodynamics and function in stroke-prone spontaneously hypertensive rats (SHRSP).
Topics: Animals; Body Weight; Calcium Channel Blockers; Cerebrovascular Disorders; Dihydropyridines; Hemodyn | 1989 |
Acute and subacute toxicity of 2,6-dimethyl-3,5-dimethoxycarbonyl-4-(o-difluoromethoxyphenyl)-1 ,4-dihydropyridine (PP-1466).
Topics: Administration, Oral; Animals; Blood Chemical Analysis; Body Weight; Calcium Channel Blockers; Dogs; | 1985 |
[Effect of nicardipine on cholesterol-fed S.H.R].
Topics: Animals; Aorta; Arteriosclerosis; Body Weight; Heart Rate; Hyperlipidemias; Hypertension; Lipids; Li | 1985 |