nicardipine has been researched along with Autonomic Dysreflexia in 2 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
Autonomic Dysreflexia: A syndrome associated with damage to the spinal cord above the mid thoracic level (see SPINAL CORD INJURIES) characterized by a marked increase in the sympathetic response to minor stimuli such as bladder or rectal distention. Manifestations include HYPERTENSION; TACHYCARDIA (or reflex bradycardia); FEVER; FLUSHING; and HYPERHIDROSIS. Extreme hypertension may be associated with a STROKE. (From Adams et al., Principles of Neurology, 6th ed, pp538 and 1232; J Spinal Cord Med 1997;20(3):355-60)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Then nicardipine 1 mg i." | 5.35 | [Case of autonomic hyperreflexia treated with intravenous nicardipine]. ( Hirota, K; Ishihara, H; Kimura, F; Saito, J, 2009) |
| "Autonomic dysreflexia is a hypertensive episode in spinal cord-injured individuals induced by exaggerated sympathetic activity and thought to be alpha-adrenergic mediated." | 2.75 | Sympathetic nonadrenergic transmission contributes to autonomic dysreflexia in spinal cord-injured individuals. ( Danser, AH; Deinum, J; Geurts, AC; Groothuis, JT; Hopman, MT; Pickkers, P; Rongen, GA; Smits, P, 2010) |
| "Then nicardipine 1 mg i." | 1.35 | [Case of autonomic hyperreflexia treated with intravenous nicardipine]. ( Hirota, K; Ishihara, H; Kimura, F; Saito, J, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saito, J | 1 |
| Kimura, F | 1 |
| Ishihara, H | 1 |
| Hirota, K | 1 |
| Groothuis, JT | 1 |
| Rongen, GA | 1 |
| Deinum, J | 1 |
| Pickkers, P | 1 |
| Danser, AH | 1 |
| Geurts, AC | 1 |
| Smits, P | 1 |
| Hopman, MT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pilot Study of Mecamylamine for Autonomic Dysreflexia Prophylaxis[NCT03914677] | Phase 4 | 5 participants (Anticipated) | Interventional | 2019-06-13 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for nicardipine and Autonomic Dysreflexia
| Article | Year |
|---|---|
Sympathetic nonadrenergic transmission contributes to autonomic dysreflexia in spinal cord-injured individuals.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Angiotensin II; Autonomic Dysreflexia; Autonomic Nervous | 2010 |
1 other study available for nicardipine and Autonomic Dysreflexia
| Article | Year |
|---|---|
[Case of autonomic hyperreflexia treated with intravenous nicardipine].
Topics: Adult; Anesthesia, Intravenous; Autonomic Dysreflexia; Colostomy; Humans; Infusions, Intravenous; In | 2009 |