nicardipine has been researched along with Asthma in 11 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The bronchodilatory activity of one beta 2-stimulation (procaterol) and one calcium antagonist (nicardipine) both recently introduced was compared in a group of chronic asthmatics in the clinical remission phase." | 9.06 | [Comparison of the bronchodilating activity of procaterol and nicardipine in chronic forms of bronchial asthma]. ( Ardizzi, A; Barberis, S; Ciotta, D; Galietti, F; Giorgis, GE; Oliaro, A, 1987) |
| "The inhibitory effect of nicardipine, a calcium antagonist, on the antigen- and anti-IgE-induced histamine release from basophilic leucocytes of patients with bronchial asthma was examined." | 7.67 | The calcium antagonist, nicardipine, inhibits antigen-stimulated and anti-IgE-induced histamine release from basophilic leucocytes of atopic asthmatics. ( Kimura, I; Kitani, H; Komagoe, H; Maeda, M; Morinaga, H; Nakagawa, S; Ohtani, J; Takahashi, K; Tanizaki, Y, 1985) |
| "A study was carried out in 10 patients with chronic non-severe asthma to investigate the effects of prolonged treatment with the calcium blocker, nicardipine." | 7.67 | Some effects of prolonged treatment with nicardipine in chronic bronchial asthma. ( Bottino, G; Gianotti, A; Moscatelli, P, 1987) |
| "The bronchodilatory activity of one beta 2-stimulation (procaterol) and one calcium antagonist (nicardipine) both recently introduced was compared in a group of chronic asthmatics in the clinical remission phase." | 5.06 | [Comparison of the bronchodilating activity of procaterol and nicardipine in chronic forms of bronchial asthma]. ( Ardizzi, A; Barberis, S; Ciotta, D; Galietti, F; Giorgis, GE; Oliaro, A, 1987) |
| "A comparison is presented of the protective effect of ultrasound mist induced by nicardipine + fenoterol and nicardipine + fenoterol + ipratropium bromide in a group of 11 patients with chronic bronchial asthma in a phase of relative clinical stability." | 5.06 | [Comparison of protective effects induced by the ultrasonic mist of nicardipine + fenoterol versus nicardipine + fenoterol + ipratropium bromide]. ( Barberis, S; Ciotta, D; Galietti, F; Giorgis, GE; Miravalle, C; Oliaro, A, 1988) |
| "We tested the effect of nicardipine in experimental allergic asthma." | 3.74 | Calcium channel blocker prevents T helper type 2 cell-mediated airway inflammation. ( Cabral, MD; Druet, P; Gallard, A; Gomes, B; Guéry, JC; Leclerc, C; Mariamé, B; Moreau, M; Paulet, P; Pelletier, L; Savignac, M, 2007) |
| "The inhibitory effect of nicardipine, a calcium antagonist, on the antigen- and anti-IgE-induced histamine release from basophilic leucocytes of patients with bronchial asthma was examined." | 3.67 | The calcium antagonist, nicardipine, inhibits antigen-stimulated and anti-IgE-induced histamine release from basophilic leucocytes of atopic asthmatics. ( Kimura, I; Kitani, H; Komagoe, H; Maeda, M; Morinaga, H; Nakagawa, S; Ohtani, J; Takahashi, K; Tanizaki, Y, 1985) |
| "A study was carried out in 10 patients with chronic non-severe asthma to investigate the effects of prolonged treatment with the calcium blocker, nicardipine." | 3.67 | Some effects of prolonged treatment with nicardipine in chronic bronchial asthma. ( Bottino, G; Gianotti, A; Moscatelli, P, 1987) |
| "In 43 patients suffering from bronchial asthma, the data on patients with normal and high systemic arterial pressure were correlated on the basis of studying external respiratory function and pulmonary circulation." | 1.28 | [The characteristics of the lung microcirculation and external respiratory function in bronchial asthma patients with systemic arterial hypertension]. ( Amosov, VI; Iartseva, EE; Sinitsyna, TM; Zhdanov, VF, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (72.73) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baraldi, PG | 1 |
| Preti, D | 1 |
| Materazzi, S | 1 |
| Geppetti, P | 1 |
| Gomes, B | 1 |
| Cabral, MD | 1 |
| Gallard, A | 1 |
| Savignac, M | 1 |
| Paulet, P | 1 |
| Druet, P | 1 |
| Mariamé, B | 1 |
| Moreau, M | 1 |
| Leclerc, C | 1 |
| Guéry, JC | 1 |
| Pelletier, L | 1 |
| Koshino, T | 2 |
| Zhdanov, VF | 1 |
| Amosov, VI | 1 |
| Sinitsyna, TM | 1 |
| Iartseva, EE | 1 |
| Tanizaki, Y | 2 |
| Komagoe, H | 2 |
| Morinaga, H | 1 |
| Ohtani, J | 2 |
| Nakagawa, S | 1 |
| Maeda, M | 1 |
| Kitani, H | 2 |
| Takahashi, K | 2 |
| Kimura, I | 2 |
| Sudo, M | 1 |
| Tada, S | 1 |
| Ardizzi, A | 1 |
| Barberis, S | 2 |
| Giorgis, GE | 2 |
| Oliaro, A | 2 |
| Galietti, F | 2 |
| Ciotta, D | 2 |
| Miravalle, C | 1 |
| Moscatelli, P | 2 |
| Bottino, G | 2 |
| Gianotti, A | 2 |
| Costa, E | 1 |
| Fujimura, M | 1 |
| Nishioka, S | 1 |
| Okafuji, K | 1 |
| Minami, S | 1 |
| Kanamori, K | 1 |
| Matsuda, T | 1 |
| Ishizaki, T | 1 |
| Saga, T | 1 |
| Miyabo, S | 1 |
1 review available for nicardipine and Asthma
| Article | Year |
|---|---|
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Asthma; Humans; Ion Channel Gating; Neurons; Pain; Pe | 2010 |
3 trials available for nicardipine and Asthma
| Article | Year |
|---|---|
[Comparison of the bronchodilating activity of procaterol and nicardipine in chronic forms of bronchial asthma].
Topics: Adult; Asthma; Bronchodilator Agents; Chronic Disease; Double-Blind Method; Ethanolamines; Female; H | 1987 |
[Comparison of protective effects induced by the ultrasonic mist of nicardipine + fenoterol versus nicardipine + fenoterol + ipratropium bromide].
Topics: Aerosols; Asthma; Atropine Derivatives; Clinical Trials as Topic; Double-Blind Method; Drug Combinat | 1988 |
Effect of nicardipine on acetylcholine-induced bronchoconstriction in asthmatic subjects.
Topics: Acetylcholine; Adolescent; Adult; Asthma; Bronchial Spasm; Double-Blind Method; Hemodynamics; Humans | 1988 |
7 other studies available for nicardipine and Asthma
| Article | Year |
|---|---|
Calcium channel blocker prevents T helper type 2 cell-mediated airway inflammation.
Topics: Administration, Intranasal; Animals; Asthma; Bronchoalveolar Lavage Fluid; Calcium; Calcium Channel | 2007 |
[The effects of Ca++ antagonists nifedipine and nicardipine on slow reacting substance of anaphylaxis (SRS-A) mediated bronchoconstriction in guinea pig].
Topics: Animals; Asthma; Calcium Channel Blockers; Depression, Chemical; Guinea Pigs; Male; Mast Cells; Nica | 1984 |
[The characteristics of the lung microcirculation and external respiratory function in bronchial asthma patients with systemic arterial hypertension].
Topics: Adult; Asthma; Fenoterol; Humans; Hypertension; Lung; Microcirculation; Middle Aged; Nicardipine; Re | 1991 |
The calcium antagonist, nicardipine, inhibits antigen-stimulated and anti-IgE-induced histamine release from basophilic leucocytes of atopic asthmatics.
Topics: Antibodies, Anti-Idiotypic; Antigens; Asthma; Basophils; Calcium Channel Blockers; Histamine Release | 1985 |
[Inhibition of a calcium antagonist, nicardipine, of histamine release from basophil leukocytes of patients with bronchial asthma].
Topics: Adolescent; Adult; Aged; Asthma; Basophils; Calcium Channel Blockers; Child; Depression, Chemical; F | 1985 |
Some effects of prolonged treatment with nicardipine in chronic bronchial asthma.
Topics: Administration, Oral; Adolescent; Adult; Asthma; Chronic Disease; Drug Evaluation; Female; Forced Ex | 1987 |
Effects of Ca2+ antagonist, nicardipine, on experimental asthma with special reference to slow reacting substance of anaphylaxis.
Topics: Airway Resistance; Animals; Antigens; Asthma; Calcium Channel Blockers; Guinea Pigs; Male; Nicardipi | 1985 |