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nicardipine and Arrhythmia

nicardipine has been researched along with Arrhythmia in 12 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Research Excerpts

ExcerptRelevanceReference
"In an open, randomized, multicenter trial, intravenous nicardipine was compared with sodium nitroprusside in 74 patients with hypertension (mean arterial pressure [MAP] greater than or equal to 100 mm Hg) following coronary artery bypass surgery."9.07Comparison of nicardipine and sodium nitroprusside in the treatment of paroxysmal hypertension following aortocoronary bypass surgery. ( David, D; Dubois, C; Loria, Y, 1991)
"The aim of the study was to compare the effect of slow-release (SR) nicardipine, placebo and chlorthalidone on hypertension-related arrhythmias evaluating 24-h ambulatory ECG."9.06Hypertension and arrhythmias: effects of slow-release nicardipine vs chlorthalidone: a double-blind crossover study. ( Celentano, A; de Divitiis, O; Galderisi, M; Garofalo, M; Mureddu, GF; Tammaro, P, 1990)
"To examine whether nicardipine, a dihydropyridine derivative, limits size of myocardial infarction, and to compare the protective effects of nicardipine administered before and early and late after coronary artery occlusion, 99mTc-labeled albumin microspheres were injected into the left atrium during 5 min temporary coronary artery occlusion to determine the extent of the hypoperfused zone (the area at risk)."7.67Comparative effects of nicardipine, a new calcium antagonist, on size of myocardial infarction after coronary artery occlusion in dogs. ( Endo, T; Fujita, S; Hayakawa, H; Iida, N; Kikuchi, K; Kiuchi, K; Nejima, J; Okumura, H, 1986)
"In an open, randomized, multicenter trial, intravenous nicardipine was compared with sodium nitroprusside in 74 patients with hypertension (mean arterial pressure [MAP] greater than or equal to 100 mm Hg) following coronary artery bypass surgery."5.07Comparison of nicardipine and sodium nitroprusside in the treatment of paroxysmal hypertension following aortocoronary bypass surgery. ( David, D; Dubois, C; Loria, Y, 1991)
"The aim of the study was to compare the effect of slow-release (SR) nicardipine, placebo and chlorthalidone on hypertension-related arrhythmias evaluating 24-h ambulatory ECG."5.06Hypertension and arrhythmias: effects of slow-release nicardipine vs chlorthalidone: a double-blind crossover study. ( Celentano, A; de Divitiis, O; Galderisi, M; Garofalo, M; Mureddu, GF; Tammaro, P, 1990)
" Nicardipine provides a good control of vasoconstriction during phaeochromocytoma surgery with limited risk of serious hypotension after tumour removal."3.70Haemodynamic heterogeneity and treatment with the calcium channel blocker nicardipine during phaeochromocytoma surgery. ( Colson, P; Dareau, S; Mann, C; Ribstein, J; Ryckwaert, F, 1998)
"To examine whether nicardipine, a dihydropyridine derivative, limits size of myocardial infarction, and to compare the protective effects of nicardipine administered before and early and late after coronary artery occlusion, 99mTc-labeled albumin microspheres were injected into the left atrium during 5 min temporary coronary artery occlusion to determine the extent of the hypoperfused zone (the area at risk)."3.67Comparative effects of nicardipine, a new calcium antagonist, on size of myocardial infarction after coronary artery occlusion in dogs. ( Endo, T; Fujita, S; Hayakawa, H; Iida, N; Kikuchi, K; Kiuchi, K; Nejima, J; Okumura, H, 1986)
"Verapamil was more effective than diltiazem."1.27Comparison of the effects of calcium channel blockers and antiarrhythmic drugs on digitalis-induced oscillatory afterpotentials on canine Purkinje fiber. ( Endou, K; Sato, T; Yamamoto, H, 1987)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19903 (25.00)18.7374
1990's5 (41.67)18.2507
2000's4 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Guo, D1
Zhao, X1
Wu, Y1
Liu, T1
Kowey, PR1
Yan, GX1
Grant, AO1
Tranquillo, J1
Nozawa, H1
Akiyama, Y1
Sunaga, S1
Tsurita, G1
Colson, P1
Ryckwaert, F1
Ribstein, J1
Mann, C1
Dareau, S1
Atlee, JL1
Dhamee, MS1
Olund, TL1
George, V1
David, D1
Dubois, C1
Loria, Y1
Pepine, CJ1
Lambert, CR1
Matsuda, F1
Kinney, WW1
Wright, W1
Kambam, JR1
Galderisi, M1
Celentano, A1
Tammaro, P1
Garofalo, M1
Mureddu, GF1
de Divitiis, O1
Baba, A1
Arita, M1
Masuyama, Y1
Endou, K1
Yamamoto, H1
Sato, T1
Endo, T1
Nejima, J1
Fujita, S1
Kiuchi, K1
Iida, N1
Kikuchi, K1
Hayakawa, H1
Okumura, H1

Reviews

1 review available for nicardipine and Arrhythmia

ArticleYear
Cardiovascular effects of nicardipine.
    Angiology, 1990, Volume: 41, Issue:11 Pt 2

    Topics: Animals; Arrhythmias, Cardiac; Cardiovascular System; Coronary Disease; Heart; Heart Failure; Hemody

1990

Trials

3 trials available for nicardipine and Arrhythmia

ArticleYear
The use of esmolol, nicardipine, or their combination to blunt hemodynamic changes after laryngoscopy and tracheal intubation.
    Anesthesia and analgesia, 2000, Volume: 90, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Anesthesia, Inhalation; Arrhythmias, Ca

2000
Comparison of nicardipine and sodium nitroprusside in the treatment of paroxysmal hypertension following aortocoronary bypass surgery.
    Journal of cardiothoracic and vascular anesthesia, 1991, Volume: 5, Issue:4

    Topics: Arrhythmias, Cardiac; Blood Pressure; Blood Transfusion; Cardiac Output; Coronary Artery Bypass; Fem

1991
Hypertension and arrhythmias: effects of slow-release nicardipine vs chlorthalidone: a double-blind crossover study.
    International journal of clinical pharmacology, therapy, and toxicology, 1990, Volume: 28, Issue:10

    Topics: Adult; Arrhythmias, Cardiac; Chlorthalidone; Delayed-Action Preparations; Double-Blind Method; Elect

1990

Other Studies

8 other studies available for nicardipine and Arrhythmia

ArticleYear
L-type calcium current reactivation contributes to arrhythmogenesis associated with action potential triangulation.
    Journal of cardiovascular electrophysiology, 2007, Volume: 18, Issue:2

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers;

2007
Action potential and QT prolongation not sufficient to cause Torsade de Pointes: role of action potential triangulation.
    Journal of cardiovascular electrophysiology, 2007, Volume: 18, Issue:2

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers;

2007
Ischemic colitis following colonoscopy in an elderly patient on cardiovascular medication.
    Endoscopy, 2007, Volume: 39 Suppl 1

    Topics: Aged, 80 and over; Arrhythmias, Cardiac; Cardiovascular Agents; Colitis, Ischemic; Colonic Neoplasms

2007
Haemodynamic heterogeneity and treatment with the calcium channel blocker nicardipine during phaeochromocytoma surgery.
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:9

    Topics: Adrenal Gland Neoplasms; Adult; Aged; Arrhythmias, Cardiac; Calcium Channel Blockers; Female; Hemody

1998
Nicardipine reduces the cardio-respiratory toxicity of intravenously administered bupivacaine in rats.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:8

    Topics: Analysis of Variance; Anesthesia, Conduction; Animals; Apnea; Arrhythmias, Cardiac; Bupivacaine; Hea

1990
[New approach to the development of Ca antagonists].
    Nihon rinsho. Japanese journal of clinical medicine, 1989, Volume: 47, Issue:8

    Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Disease; Humans; Hypertension; Nic

1989
Comparison of the effects of calcium channel blockers and antiarrhythmic drugs on digitalis-induced oscillatory afterpotentials on canine Purkinje fiber.
    Japanese heart journal, 1987, Volume: 28, Issue:5

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Digitalis; Diltiaze

1987
Comparative effects of nicardipine, a new calcium antagonist, on size of myocardial infarction after coronary artery occlusion in dogs.
    Circulation, 1986, Volume: 74, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Coronary Circulation; Coronary Disease; Dogs; Female; Hemodynamics; M

1986