nicardipine has been researched along with Aortic Dissection in 9 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "While nitroprusside is commonly used to treat severe hypertension, it is an extremely toxic drug that should only be used in rare circumstances." | 2.41 | The diagnosis and management of hypertensive crises. ( Marik, PE; Varon, J, 2000) |
| "The antenatal diagnosis of aortic dissection carries a grave prognosis." | 1.39 | Successful management of aortic dissection in a patient with Marfan syndrome during pregnancy. ( Chang, CY; Chen, PH; Lam, CW; Yang, JM, 2013) |
| "There was no death related to aortic dissection." | 1.30 | Outcome of medically treated Stanford type B aortic dissection. ( Iguchi, A; Tabayashi, K, 1998) |
| "Treatment with metoprolol and nicardipine kept his blood pressure below 130/90 mm Hg while he was supine at rest and after walking." | 1.27 | Spontaneous resolution of a dissection of the descending aorta after medical treatment with a beta blocker and a calcium antagonist. ( Hoshino, T; Ohmae, M; Sakai, A, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wong, MF | 1 |
| Yen, ZS | 1 |
| Chang, CY | 1 |
| Yang, JM | 1 |
| Lam, CW | 1 |
| Chen, PH | 1 |
| Takaba, T | 1 |
| Yokokawa, H | 1 |
| Moriyasu, K | 1 |
| Matsuo, Y | 1 |
| Nishikawa, T | 1 |
| Kataoka, D | 1 |
| Shinpo, H | 1 |
| Mizumoto, T | 1 |
| Shimono, T | 1 |
| Shikano, K | 1 |
| Takeuchi, Y | 1 |
| Tanaka, K | 1 |
| Yada, K | 1 |
| Yuasa, H | 1 |
| Kusagawa, M | 1 |
| Hirotani, T | 2 |
| Kato, Y | 1 |
| Shirota, S | 2 |
| Kameda, T | 2 |
| Mayuzumi, S | 1 |
| Iguchi, A | 1 |
| Tabayashi, K | 1 |
| Varon, J | 1 |
| Marik, PE | 1 |
| Kumamoto, T | 1 |
| Hoshino, T | 1 |
| Ohmae, M | 1 |
| Sakai, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| NICardipine Neuroprotection in AortiC Surgery (NICNACS)[NCT00508118] | Phase 2 | 7 participants (Actual) | Interventional | 2008-01-31 | Terminated (stopped due to 3/7 subjects experienced hypotension. Study was terminated.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT00508118)
Timeframe: Day of surgery
| Intervention | Time (minutes) (Median) |
|---|---|
| NICARDIPINE GROUP | 45 |
1 review available for nicardipine and Aortic Dissection
| Article | Year |
|---|---|
The diagnosis and management of hypertensive crises.
Topics: Antihypertensive Agents; Aortic Aneurysm; Aortic Dissection; Clonidine; Diazoxide; Enalaprilat; Fema | 2000 |
8 other studies available for nicardipine and Aortic Dissection
| Article | Year |
|---|---|
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. BET 1. Nicardipine hydrochloride for hypertensive crisis in patients with aortic dissection.
Topics: Aortic Aneurysm; Aortic Dissection; Critical Illness; Emergency Medicine; Emergency Service, Hospita | 2011 |
Successful management of aortic dissection in a patient with Marfan syndrome during pregnancy.
Topics: Adult; Aortic Aneurysm; Aortic Dissection; Blood Pressure; Calcium Channel Blockers; Coronary Angiog | 2013 |
[Antihypertensive therapy using nicardipine hydrochloride in the treatment of aortic aneurysm].
Topics: Adult; Aged; Aortic Aneurysm, Thoracic; Aortic Dissection; Female; Heart Rate; Humans; Hypertension; | 1995 |
[Selective cerebral perfusion and pharmacological cerebral protection in the patients with aortic arch aneurysm].
Topics: Adult; Aged; Aged, 80 and over; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Blood | 1993 |
[Surgical treatment of type A acute aortic dissection--experience of hypothermic circulatory arrest associated with the cerebroplegia].
Topics: Acute Disease; Adult; Aged; Aortic Aneurysm, Thoracic; Aortic Dissection; Blood Vessel Prosthesis; C | 1997 |
Outcome of medically treated Stanford type B aortic dissection.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aortic Aneurysm; Aortic Dis | 1998 |
Aortic arch repair using hypothermic circulatory arrest technique associated with pharmacological brain protection.
Topics: Adult; Aged; Aged, 80 and over; Aortic Aneurysm, Thoracic; Aortic Dissection; Aortic Rupture; Blood | 2000 |
Spontaneous resolution of a dissection of the descending aorta after medical treatment with a beta blocker and a calcium antagonist.
Topics: Aorta, Thoracic; Aortic Aneurysm; Aortic Dissection; Drug Therapy, Combination; Humans; Male; Metopr | 1987 |