Page last updated: 2024-11-01

nicardipine and Aortic Aneurysm, Ruptured

nicardipine has been researched along with Aortic Aneurysm, Ruptured in 3 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Research Excerpts

ExcerptRelevanceReference
" Using a propensity-score model, this patient cohort was compared to patients in the Subarachnoid Hemorrhage International Trialists (SAHIT) repository who did not receive IT nicardipine."8.12Does intrathecal nicardipine for cerebral vasospasm following subarachnoid hemorrhage correlate with reduced delayed cerebral ischemia? A retrospective propensity score-based analysis. ( Akbik, F; Ameli, P; Asbury, W; Barrow, DL; Cawley, CM; Danyluk, L; Feng, C; Garner, K; Jaja, BNR; Kolenda, J; Kraft, J; Macdonald, RL; Martin, KS; Mathew, S; Mei, Y; Moore, R; Pearce, D; Pimentel, C; Pujari, A; Sadan, O; Samuels, O; Taylor, A; Waddel, H, 2022)
" Using a propensity-score model, this patient cohort was compared to patients in the Subarachnoid Hemorrhage International Trialists (SAHIT) repository who did not receive IT nicardipine."4.12Does intrathecal nicardipine for cerebral vasospasm following subarachnoid hemorrhage correlate with reduced delayed cerebral ischemia? A retrospective propensity score-based analysis. ( Akbik, F; Ameli, P; Asbury, W; Barrow, DL; Cawley, CM; Danyluk, L; Feng, C; Garner, K; Jaja, BNR; Kolenda, J; Kraft, J; Macdonald, RL; Martin, KS; Mathew, S; Mei, Y; Moore, R; Pearce, D; Pimentel, C; Pujari, A; Sadan, O; Samuels, O; Taylor, A; Waddel, H, 2022)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Sadan, O1
Waddel, H1
Moore, R1
Feng, C1
Mei, Y1
Pearce, D1
Kraft, J1
Pimentel, C1
Mathew, S1
Akbik, F1
Ameli, P1
Taylor, A1
Danyluk, L1
Martin, KS1
Garner, K1
Kolenda, J1
Pujari, A1
Asbury, W1
Jaja, BNR1
Macdonald, RL1
Cawley, CM1
Barrow, DL1
Samuels, O1
Lassié, P1
Tentillier, E1
Thicoïpé, M1
Pinaquy, C1
Laborde, N1
Hirotani, T1
Kameda, T1
Kumamoto, T1
Shirota, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
NICardipine Neuroprotection in AortiC Surgery (NICNACS)[NCT00508118]Phase 27 participants (Actual)Interventional2008-01-31Terminated (stopped due to 3/7 subjects experienced hypotension. Study was terminated.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Duration From Initiation of Cardiopulmonary Bypass (CPB) to Electrocerebral Silence (ECS), Defined as no Discernable Electroencephalographic Activity at an Amplification of 2 Micro Volts (μV)/mm, Confirmed for 3 Minutes

(NCT00508118)
Timeframe: Day of surgery

InterventionTime (minutes) (Median)
NICARDIPINE GROUP45

Other Studies

3 other studies available for nicardipine and Aortic Aneurysm, Ruptured

ArticleYear
Does intrathecal nicardipine for cerebral vasospasm following subarachnoid hemorrhage correlate with reduced delayed cerebral ischemia? A retrospective propensity score-based analysis.
    Journal of neurosurgery, 2022, Jan-01, Volume: 136, Issue:1

    Topics: Adult; Age Factors; Aged; Aneurysm, Ruptured; Aortic Rupture; Calcium Channel Blockers; Critical Car

2022
[Traumatic rupture of the aortic isthmus in a patient with severe head injury].
    Annales francaises d'anesthesie et de reanimation, 1993, Volume: 12, Issue:1

    Topics: Adult; Aortic Rupture; Blood Pressure; Brain Injuries; Constriction; Emergencies; Humans; Intracrani

1993
Aortic arch repair using hypothermic circulatory arrest technique associated with pharmacological brain protection.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2000, Volume: 18, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aortic Aneurysm, Thoracic; Aortic Dissection; Aortic Rupture; Blood

2000