nicardipine has been researched along with Anoxia, Brain in 8 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We compared the effects of the systemic hypotensive drugs prostaglandin E1 (PGE1) and nicardipine on the cerebral microcirculation and on the cerebrovascular reactivities to hypercapnia and hypoxia." | 3.72 | The comparative effects of prostaglandin E1 and nicardipine on cerebral microcirculation in rabbits. ( Dohi, S; Iida, H; Iida, M; Takenaka, M; Uchida, M, 2003) |
| "To provide evidence to support the calcium hypothesis of cerebral ischemia, we examined the effects of extracellular calcium and calcium antagonists (verapamil, flunarizine, nicardipine) on in vitro 'ischemia' using guinea pig hippocampal slices." | 3.68 | Effects of calcium and calcium antagonists against deprivation of glucose and oxygen in guinea pig hippocampal slices. ( Amagasa, M; Ogawa, A; Yoshimoto, T, 1990) |
| "Nicardipine was effective in 87% of the patients (with intravenous beta blockers in 4 patients), with a 19." | 2.73 | Management of hypertensive emergencies in acute brain disease: evaluation of the treatment effects of intravenous nicardipine on cerebral oxygenation. ( Narotam, PK; Nathoo, N; Puri, V; Roberts, JM; Taylon, C; Vora, Y, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Narotam, PK | 1 |
| Puri, V | 1 |
| Roberts, JM | 1 |
| Taylon, C | 1 |
| Vora, Y | 1 |
| Nathoo, N | 1 |
| Takenaka, M | 1 |
| Iida, H | 1 |
| Iida, M | 1 |
| Uchida, M | 1 |
| Dohi, S | 1 |
| Amagasa, M | 1 |
| Ogawa, A | 1 |
| Yoshimoto, T | 1 |
| Levene, MI | 1 |
| Gibson, NA | 1 |
| Fenton, AC | 1 |
| Papathoma, E | 1 |
| Barnett, D | 1 |
| Yamazaki, M | 1 |
| Yamamoto, M | 1 |
| Masuda, A | 1 |
| Ito, Y | 1 |
| Kawahara, M | 1 |
| Nakagomi, T | 1 |
| Kassell, NF | 1 |
| Sasaki, T | 1 |
| Fujiwara, S | 1 |
| Lehman, RM | 1 |
| Johshita, H | 1 |
| Torner, JC | 1 |
| Shimizu, Y | 1 |
| Montero, JL | 1 |
| Grau, M | 1 |
| Balasch, J | 1 |
1 trial available for nicardipine and Anoxia, Brain
| Article | Year |
|---|---|
Management of hypertensive emergencies in acute brain disease: evaluation of the treatment effects of intravenous nicardipine on cerebral oxygenation.
Topics: Acute Disease; Adult; Aged; Antihypertensive Agents; Blood Pressure; Brain; Brain Injuries; Cerebral | 2008 |
7 other studies available for nicardipine and Anoxia, Brain
| Article | Year |
|---|---|
The comparative effects of prostaglandin E1 and nicardipine on cerebral microcirculation in rabbits.
Topics: Alprostadil; Animals; Arterioles; Blood Pressure; Calcium Channel Blockers; Cerebrovascular Circulat | 2003 |
Effects of calcium and calcium antagonists against deprivation of glucose and oxygen in guinea pig hippocampal slices.
Topics: Action Potentials; Animals; Brain Ischemia; Calcium; Calcium Channel Blockers; Disease Models, Anima | 1990 |
The use of a calcium-channel blocker, nicardipine, for severely asphyxiated newborn infants.
Topics: Asphyxia Neonatorum; Blood Pressure; Brain Damage, Chronic; Cerebral Cortex; Cerebrovascular Circula | 1990 |
[The effects of nicardipine on morphological changes and calcium accumulation during ischemic hypoxia in pyramidal nerve cells in the rat cerebral cortex].
Topics: Animals; Brain Ischemia; Calcium; Hypoxia, Brain; Male; Nicardipine; Pyramidal Tracts; Rats; Rats, I | 1989 |
Effect of hypoxia on the contractile response to KCl, prostaglandin F2 alpha, and hemoglobin.
Topics: Animals; Basilar Artery; Calcium; Dinoprost; Dogs; Endothelium, Vascular; Female; Hemoglobins; Hypox | 1987 |
[Effect of the calcium entry blockers nicardipine and nimodipine on cerebral function following global anoxia in the rat].
Topics: Animals; Brain; Calcium Channel Blockers; Hypoxia, Brain; Male; Nicardipine; Nicotinic Acids; Nifedi | 1986 |
Nicardipine: protection against brain hypoxia.
Topics: Animals; Cerebral Cortex; Electroencephalography; Hypoxia, Brain; Male; Mice; Nicardipine; Nifedipin | 1986 |